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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Luzp1 | Rat | 1,2-dichloroethane | increases expression | ISO | Luzp1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of LUZP1 mRNA | CTD | PMID:28960355 | Luzp1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LUZP1 mRNA | CTD | PMID:22206623 | Luzp1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LUZP1 mRNA | CTD | PMID:22298810 and PMID:34747641 | Luzp1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Luzp1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LUZP1 mRNA | CTD | PMID:21570461 and PMID:26377647 | Luzp1 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with pyrogallol 1 more ... | CTD | PMID:38598786 | Luzp1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of LUZP1 mRNA | CTD | PMID:21346803 | Luzp1 | Rat | 2-methylcholine | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of LUZP1 mRNA | CTD | PMID:21179406 | Luzp1 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of LUZP1 mRNA | CTD | PMID:18648102 | Luzp1 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | LUZP1 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of LUZP1 gene | CTD | PMID:31601247 | Luzp1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of LUZP1 mRNA | CTD | PMID:24780913 | Luzp1 | Rat | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of LUZP1 protein | CTD | PMID:33236894 | Luzp1 | Rat | aflatoxin B1 | increases methylation | ISO | LUZP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of LUZP1 intron | CTD | PMID:30157460 | Luzp1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of LUZP1 mRNA | CTD | PMID:16483693 | Luzp1 | Rat | antirheumatic drug | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of LUZP1 mRNA | CTD | PMID:24449571 | Luzp1 | Rat | aristolochic acid A | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of LUZP1 mRNA | CTD | PMID:33212167 | Luzp1 | Rat | arsenite(3-) | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to LUZP1 mRNA] | CTD | PMID:32406909 | Luzp1 | Rat | benzo[a]pyrene | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of LUZP1 mRNA | CTD | PMID:19770486 | Luzp1 | Rat | benzo[a]pyrene | affects methylation | ISO | LUZP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LUZP1 5' UTR and Benzo(a)pyrene affects the methylation of LUZP1 promoter | CTD | PMID:27901495 | Luzp1 | Rat | benzo[a]pyrene | increases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LUZP1 mRNA | CTD | PMID:22228805 | Luzp1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LUZP1 mRNA | CTD | PMID:25181051 | Luzp1 | Rat | bisphenol A | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LUZP1 gene | CTD | PMID:31601247 | Luzp1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LUZP1 mRNA | CTD | PMID:32145629 and PMID:34947998 | Luzp1 | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of LUZP1 protein | CTD | PMID:28903499 | Luzp1 | Rat | cadmium atom | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of LUZP1 mRNA | CTD | PMID:23369406 | Luzp1 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of LUZP1 mRNA | CTD | PMID:33453195 | Luzp1 | Rat | cadmium dichloride | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of LUZP1 mRNA | CTD | PMID:38568856 | Luzp1 | Rat | cadmium dichloride | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of LUZP1 mRNA | CTD | PMID:24982889 | Luzp1 | Rat | caffeine | affects phosphorylation | ISO | LUZP1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of LUZP1 protein | CTD | PMID:35688186 | Luzp1 | Rat | carbamazepine | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of LUZP1 mRNA | CTD | PMID:25979313 | Luzp1 | Rat | carbon nanotube | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of LUZP1 mRNA | CTD | PMID:25554681 | Luzp1 | Rat | carnosic acid | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | salvin results in decreased expression of LUZP1 protein | CTD | PMID:35926579 | Luzp1 | Rat | chromium(6+) | affects expression | ISO | Luzp1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of LUZP1 mRNA | CTD | PMID:28472532 | Luzp1 | Rat | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of LUZP1 protein | CTD | PMID:22023808 | Luzp1 | Rat | cisplatin | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of LUZP1 mRNA | CTD | PMID:27392435 | Luzp1 | Rat | cobalt dichloride | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of LUZP1 mRNA | CTD | PMID:19320972 | Luzp1 | Rat | coumarin | affects phosphorylation | ISO | LUZP1 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of LUZP1 protein | CTD | PMID:35688186 | Luzp1 | Rat | crocidolite asbestos | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Asbestos and Crocidolite affects the expression of LUZP1 mRNA | CTD | PMID:24160326 | Luzp1 | Rat | cyclosporin A | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of LUZP1 mRNA | CTD | PMID:27989131 | Luzp1 | Rat | Dibutyl phosphate | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of LUZP1 mRNA | CTD | PMID:37042841 | Luzp1 | Rat | dibutyl phthalate | increases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of LUZP1 mRNA | CTD | PMID:21266533 | Luzp1 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of LUZP1 mRNA | CTD | PMID:21266533 | Luzp1 | Rat | dorsomorphin | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LUZP1 mRNA | CTD | PMID:27188386 | Luzp1 | Rat | doxorubicin | increases oxidation | EXP | | 6480464 | Doxorubicin results in increased oxidation of LUZP1 protein | CTD | PMID:28818578 | Luzp1 | Rat | enzyme inhibitor | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of LUZP1 protein | CTD | PMID:23301498 | Luzp1 | Rat | fenthion | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of LUZP1 mRNA | CTD | PMID:34813904 | Luzp1 | Rat | folic acid | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of LUZP1 mRNA | CTD | PMID:21867686 | Luzp1 | Rat | FR900359 | affects phosphorylation | ISO | LUZP1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of LUZP1 protein | CTD | PMID:37730182 | Luzp1 | Rat | fulvestrant | increases methylation | ISO | LUZP1 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of LUZP1 gene | CTD | PMID:31601247 | Luzp1 | Rat | fulvestrant | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LUZP1 gene | CTD | PMID:31601247 | Luzp1 | Rat | furfural | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of LUZP1 protein and [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of LUZP1 protein | CTD | PMID:38598786 | Luzp1 | Rat | glyphosate | increases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Glyphosate results in increased expression of LUZP1 mRNA | CTD | PMID:35897073 | Luzp1 | Rat | isobutanol | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LUZP1 mRNA | CTD | PMID:29432896 | Luzp1 | Rat | ivermectin | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LUZP1 protein | CTD | PMID:32959892 | Luzp1 | Rat | methylmercury chloride | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of LUZP1 mRNA | CTD | PMID:28001369 | Luzp1 | Rat | paracetamol | affects expression | ISO | Luzp1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LUZP1 mRNA | CTD | PMID:17562736 | Luzp1 | Rat | paracetamol | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of LUZP1 mRNA | CTD | PMID:22230336 | Luzp1 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of LUZP1 mRNA | CTD | PMID:37995155 | Luzp1 | Rat | quercetin | decreases phosphorylation | ISO | LUZP1 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of LUZP1 protein | CTD | PMID:35688186 | Luzp1 | Rat | SB 431542 | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LUZP1 mRNA | CTD | PMID:27188386 | Luzp1 | Rat | serpentine asbestos | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Asbestos and Serpentine affects the expression of LUZP1 mRNA | CTD | PMID:24160326 | Luzp1 | Rat | silicon dioxide | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of LUZP1 mRNA | CTD | PMID:25895662 | Luzp1 | Rat | sodium arsenite | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of LUZP1 mRNA | CTD | PMID:38568856 | Luzp1 | Rat | sodium chloride | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of LUZP1 protein more ... | CTD | PMID:38598786 | Luzp1 | Rat | sunitinib | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of LUZP1 mRNA | CTD | PMID:31533062 | Luzp1 | Rat | thimerosal | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Thimerosal results in decreased expression of LUZP1 mRNA | CTD | PMID:24675092 | Luzp1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of LUZP1 mRNA | CTD | PMID:34492290 | Luzp1 | Rat | thiram | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Thiram results in increased expression of LUZP1 mRNA | CTD | PMID:38568856 | Luzp1 | Rat | titanium dioxide | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of LUZP1 mRNA | CTD | PMID:23557971 | Luzp1 | Rat | titanium dioxide | decreases methylation | ISO | Luzp1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of LUZP1 promoter | CTD | PMID:35295148 | Luzp1 | Rat | titanium dioxide | increases methylation | ISO | Luzp1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of LUZP1 promoter | CTD | PMID:35295148 | Luzp1 | Rat | trichostatin A | decreases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of LUZP1 mRNA | CTD | PMID:26272509 | Luzp1 | Rat | trichostatin A | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | trichostatin A affects the expression of LUZP1 mRNA | CTD | PMID:28542535 | Luzp1 | Rat | trichostatin A | multiple interactions | ISO | LUZP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LUZP1 mRNA | CTD | PMID:27188386 | Luzp1 | Rat | triphenyl phosphate | affects expression | ISO | LUZP1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of LUZP1 mRNA | CTD | PMID:37042841 | Luzp1 | Rat | troglitazone | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of LUZP1 mRNA | CTD | PMID:28973697 | Luzp1 | Rat | urethane | increases expression | ISO | LUZP1 (Homo sapiens) | 6480464 | Urethane results in increased expression of LUZP1 mRNA | CTD | PMID:28818685 | Luzp1 | Rat | valproic acid | decreases expression | ISO | Luzp1 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of LUZP1 mRNA | CTD | PMID:21427059 | Luzp1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LUZP1 mRNA | CTD | PMID:23555832 | |