Comt<sup>em1Mcwi</sup> (catechol-O-methyltransferase; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) - Rat Genome Database

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Gene: Comtem1Mcwi (catechol-O-methyltransferase; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) Rattus norvegicus
Symbol: Comtem1Mcwi
Name: catechol-O-methyltransferase; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
RGD ID: 5687725
Description: This allele was made by ZFN mutagenesis. The resulting mutation is a 14-bp frameshift deletion in exon 4 (del 639-652)
Type: allele  of Comt  
Previously known as: Comt^[em1Mcwi]; Comtem1Mcwi
Is Marker For: Strains:   SS-Comtem1Mcwi  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Cytogenetic Map11 RGD


References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains


Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Comtem1Mcwi-var1 chr11 86731828 86731841 CTCAATGGGGCATC - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Comtem1Mcwi



Nucleotide Sequences
RefSeq Transcripts NM_012531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Additional Information