Cdh13<sup>em1Mcwi</sup> (cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) - Rat Genome Database

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Gene: Cdh13em1Mcwi (cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) Rattus norvegicus
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Symbol: Cdh13em1Mcwi
Name: cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
RGD ID: 5131919
Description: This allele was made by zinc finger nuclease mutagenesis. The resulting mutation is an 8-bp frameshift deletion in exon 1 (del 104-111).
ASSOCIATED WITH abnormal cue-induced reinstatement of an extinguished operant behavior for a cocaine reinforcer; saccharin preference; ASSOCIATED WITH substance-related disorder
Type: allele  of Cdh13  
Previously known as: Cdh13^[em1Mcwi]; Cdh13em1Mcwi
Is Marker For: Strains:   SS-Cdh13em1Mcwi  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map19 RGD




Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning. King CP, etal., Genes Brain Behav. 2017 Sep;16(7):686-698. doi: 10.1111/gbb.12382. Epub 2017 May 2.
3. PhysGen Knockouts PhysGen Knockout strains

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Cdh13em1Mcwi-var1 chr19 50848896 50848903 CTGCTGTC - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Cdh13em1Mcwi
SS-Cdh13em1Mcwi    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_138889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information