Pde6b<sup>em1Baek</sup> (phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek) - Rat Genome Database

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Gene: Pde6bem1Baek (phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek) Rattus norvegicus
Symbol: Pde6bem1Baek
Name: phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek
RGD ID: 42721979
Description: Cpf1-CRISPR system was injected to SD embryos to induced an 11-bp deletion in exon 1 of rat Pde6b.
ASSOCIATED WITH abnormal retina blood vessel pattern; increased retina apoptosis; retina degeneration; ASSOCIATED WITH retinitis pigmentosa
Type: allele  of Pde6b  
Previously known as: Pde6b^[em1Baek]
Is Marker For: Strains:   SD-Pde6bem1Baek  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Disease Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. Development of a Pde6b Gene Knockout Rat Model for Studies of Degenerative Retinal Diseases. Yeo JH, etal., Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1519-1526. doi: 10.1167/iovs.18-25556.


Related Rat Strains
The following Strains have been annotated to Pde6bem1Baek



Nucleotide Sequences

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-25 Pde6bem1Baek  phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek  Pde6bem1Baek    Name changed 629549 APPROVED