Lrp5<sup>em1Vari</sup> (LDL receptor related protein 5;CRISPR/Cas9 induced mutant 1, Vari) - Rat Genome Database

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Gene: Lrp5em1Vari (LDL receptor related protein 5;CRISPR/Cas9 induced mutant 1, Vari) Rattus norvegicus
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Symbol: Lrp5em1Vari
Name: LDL receptor related protein 5;CRISPR/Cas9 induced mutant 1, Vari
RGD ID: 41404647
Description: CRISPR/Cas9 system was used to introduce a 18-bp deletion of exon 2 in the rat Lrp5 gene of Crl:SD embryos.
ASSOCIATED WITH abnormal femur morphology; abnormal retina blood vessel morphology; abnormal retina blood vessel pattern
Type: allele  of Lrp5  
Previously known as: Lrp5^[em1Vari]
Is Marker For: Strains:   SD-Lrp5em1Vari   SD-Lrp5em1Vari/Rrrc  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Low-Density Lipoprotein Receptor-Related Protein 5-Deficient Rats Have Reduced Bone Mass and Abnormal Development of the Retinal Vasculature. Ubels JL, etal., CRISPR J. 2020 Aug;3(4):284-298. doi: 10.1089/crispr.2020.0009.

Genomics


Related Rat Strains
The following Strains have been annotated to Lrp5em1Vari


Expression


Sequence

Nucleotide Sequences


Additional Information