Ets1<sup>em1Mcwi</sup> (v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ets1em1Mcwi (v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin) Rattus norvegicus
Analyze
Symbol: Ets1em1Mcwi
Name: v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
RGD ID: 4139856
Description: This allele was made by zinc finger nuclease mutagenesis. The resulting mutation is an 8-bp frameshift deletion in exon 3 (del 515-522).
ASSOCIATED WITH decreased circulating creatinine level
Type: allele  of Ets1  
Previously known as: Ets1em1Mcwi
Is Marker For: Strains:   SS-Ets1em1Mcwi   SS-Ets1em1Mcwi-/+  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map8 RGD


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat. Feng W, etal., Kidney Int. 2020 Mar;97(3):528-537. doi: 10.1016/j.kint.2019.09.025. Epub 2019 Oct 22.
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains

Genomics


Related Rat Strains
The following Strains have been annotated to Ets1em1Mcwi


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information