LOC120093086 (sulfotransferase 1C2-like) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: LOC120093086 (sulfotransferase 1C2-like) Rattus norvegicus
Analyze
Symbol: LOC120093086 (Ensembl: Sult1c2)
Name: sulfotransferase 1C2-like (Ensembl:sulfotransferase family 1C member 2)
RGD ID: 41320429
Description: Enables aryl sulfotransferase activity. Involved in sulfation. Located in lysosome.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: sulfotransferase 1C2; sulfotransferase 1C2A; sulfotransferase 1C2A-like
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr897,032,812 - 7,051,281 (+)NCBIGRCr8
mRatBN7.296,962,604 - 7,131,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl96,745,700 - 7,131,245 (+)EnsemblmRatBN7.2 Ensembl
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
sulfation  (IBA,IDA)

Cellular Component
cytoplasm  (IBA,IEA)
lysosome  (IDA)
mitochondrion  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Enzymatic properties, tissue-specific expression, and lysosomal location of two highly homologous rat SULT1C2 sulfotransferases. Xiangrong L, etal., Biochem Biophys Res Commun 2000 May 27;272(1):242-50.

Genomics

Variants

.
Variants in LOC120093086
401 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_039084404   ⟹   XP_038940332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr897,032,813 - 7,051,281 (+)NCBI
mRatBN7.297,112,800 - 7,131,268 (+)NCBI
RefSeq Acc Id: XM_039084405   ⟹   XP_038940333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr897,032,812 - 7,051,281 (+)NCBI
mRatBN7.297,112,800 - 7,131,268 (+)NCBI
RefSeq Acc Id: XM_039084409   ⟹   XP_038940337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr897,037,147 - 7,051,281 (+)NCBI
mRatBN7.297,117,102 - 7,131,268 (+)NCBI
RefSeq Acc Id: XP_038940332   ⟸   XM_039084404
- Peptide Label: isoform X1
- UniProtKB: Q9WUW8 (UniProtKB/Swiss-Prot),   Q3ZAV3 (UniProtKB/Swiss-Prot),   F1LZL1 (UniProtKB/Swiss-Prot),   A0A0G2JUM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940333   ⟸   XM_039084405
- Peptide Label: isoform X1
- UniProtKB: Q9WUW8 (UniProtKB/Swiss-Prot),   Q3ZAV3 (UniProtKB/Swiss-Prot),   F1LZL1 (UniProtKB/Swiss-Prot),   A0A0G2JUM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940337   ⟸   XM_039084409
- Peptide Label: isoform X2
- UniProtKB: A6KQA1 (UniProtKB/TrEMBL)
Protein Domains
Sulfotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LNK1-F1-model_v2 AlphaFold F1LNK1 1-141 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-28385 BioCyc
Ensembl Genes ENSRNOG00000065530 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061864.5 UniProtKB/TrEMBL
  ENSRNOT00000082579.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
NCBI Gene LOC120093086 ENTREZGENE
PANTHER SULFOTRANSFERASE 1C2 UniProtKB/TrEMBL
  SULFOTRANSFERASE SULT UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/TrEMBL
PhenoGen LOC120093086 PhenoGen
RatGTEx ENSRNOG00000065530 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JUM0 ENTREZGENE, UniProtKB/TrEMBL
  A6KQA1 ENTREZGENE, UniProtKB/TrEMBL
  F1LZI5_RAT UniProtKB/TrEMBL
  F1LZL1 ENTREZGENE
  Q3ZAV3 ENTREZGENE
  Q9WUW8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-27 LOC120093086  sulfotransferase 1C2-like      Symbol and Name status set to provisional 70820 PROVISIONAL