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Gene: Vldlr (very low density lipoprotein receptor) Rattus norvegicus
Symbol: Vldlr
Name: very low density lipoprotein receptor
RGD ID: 3963
Description: Predicted to have several functions, including reelin receptor activity; very-low-density lipoprotein particle binding activity; and very-low-density lipoprotein particle receptor activity. Involved in several processes, including cellular response to glucose starvation; cellular response to interleukin-1; and cellular response to lipopolysaccharide. Localizes to several cellular components, including apical part of cell; cell surface; and perinuclear region of cytoplasm. Biomarker of focal segmental glomerulosclerosis and nephrotic syndrome. Human ortholog(s) of this gene implicated in Alzheimer's disease; cerebellar ataxia, mental retardation and dysequlibrium syndrome; and dementia. Orthologous to human VLDLR (very low density lipoprotein receptor); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: very low-density lipoprotein receptor; VLDL receptor; VLDL-R
Homo sapiens (human) : VLDLR (very low density lipoprotein receptor)  HGNC  Alliance
Mus musculus (house mouse) : Vldlr (very low density lipoprotein receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vldlr (very low density lipoprotein receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : VLDLR (very low density lipoprotein receptor)
Canis lupus familiaris (dog) : VLDLR (very low density lipoprotein receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vldlr (very low density lipoprotein receptor)
Sus scrofa (pig) : VLDLR (very low density lipoprotein receptor)
Chlorocebus sabaeus (African green monkey) : VLDLR (very low density lipoprotein receptor)
Heterocephalus glaber (naked mole-rat) : Vldlr (very low density lipoprotein receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01245,236,819 - 245,273,688 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,237,736 - 245,269,205 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01252,485,275 - 252,523,202 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41230,666,736 - 230,697,748 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11230,830,758 - 230,861,771 (+)NCBI
Celera1222,002,111 - 222,033,270 (+)NCBICelera
Cytogenetic Map1q52NCBI
RH 3.4 Map11610.4RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Vldlr
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3963
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.