Rarres2<sup>em1Msu</sup> (retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rarres2em1Msu (retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu) Rattus norvegicus
Analyze
Symbol: Rarres2em1Msu
Name: retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
RGD ID: 38596341
Description: Rat zygotes, produced by mating superovulated Sprague-Dawley females with males of the same strain [Crl:CD(SD), were microinjected with CRISPR/Cas9 reagents targeting arres2 exon2. The resulting allele lacked the splice site and the first 13 aa of exon 2.
ASSOCIATED WITH decreased circulating aspartate transaminase level; decreased heart rate; decreased mean systemic arterial blood pressure
Type: allele  of Rarres2  
Is Marker For: Strains:   SD-Rarres2em1Msu  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. The chemerin knockout rat reveals chemerin dependence in female, but not male, experimental hypertension. Watts SW, etal., FASEB J. 2018 Jun 15:fj201800479. doi: 10.1096/fj.201800479.

Genomics


Related Rat Strains
The following Strains have been annotated to Rarres2em1Msu


Expression


Sequence

Nucleotide Sequences


Additional Information