Tbc1d4<sup>em1</sup> (TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,) - Rat Genome Database

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Gene: Tbc1d4em1 (TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,) Rattus norvegicus
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Symbol: Tbc1d4em1
Name: TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,
RGD ID: 38596330
Description: A 20-bp substitution deletion (TGGCGACAAGCGTTCCGGC) in the rat Tbc1d4 gene was created in outbred Wistar zygotes with CRISPR/Cas9 system.
ASSOCIATED WITH impaired glucose tolerance; insulin resistance
Type: allele  of Tbc1d4  
Previously known as: Tbc1d4em1M
Is Marker For: Strains:   WI-Tbc1d4em1Gdcz  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Whole body glucoregulation and tissue-specific glucose uptake in a novel Akt substrate of 160 kDa knockout rat model. Arias EB, etal., PLoS One. 2019 Apr 29;14(4):e0216236. doi: 10.1371/journal.pone.0216236. eCollection 2019.
2. In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats. Zheng X, etal., PLoS One. 2020 Feb 13;15(2):e0223340. doi: 10.1371/journal.pone.0223340. eCollection 2020.

Genomics


Related Rat Strains
The following Strains have been annotated to Tbc1d4em1


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-09-03 Tbc1d4em1  TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,  Tbc1d4em1M  TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,  Symbol changed 629549 APPROVED