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Imported Disease Annotations - MGIObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Syn3 | Rat | autism spectrum disorder | | ISS | Syn3 (Mus musculus) | 13592920 | | MouseDO | | |
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Imported Disease Annotations - MGIObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Syn3 | Rat | autism spectrum disorder | | ISS | Syn3 (Mus musculus) | 13592920 | | MouseDO | | |
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# | Reference Title | Reference Citation |
1. | Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. | Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
4. | Synapsin III, a novel synapsin with an unusual regulation by Ca2+. | Hosaka M and Sudhof TC, J Biol Chem 1998 May 29;273(22):13371-4. |
5. | Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. | Jaffrey SR, etal., Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3199-204. Epub 2002 Feb 26. |
6. | A third member of the synapsin gene family. | Kao HT, etal., Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4667-72. |
7. | A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. | Lam PP, etal., Mol Biol Cell. 2007 Jul;18(7):2473-80. Epub 2007 Apr 18. |
8. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
9. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
10. | GOA pipeline | RGD automated data pipeline |
11. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
12. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:10358015 | PMID:12040043 | PMID:15071120 | PMID:17114649 | PMID:25843720 |
Syn3 (Rattus norvegicus - Norway rat) |
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SYN3 (Homo sapiens - human) |
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Syn3 (Mus musculus - house mouse) |
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Syn3 (Chinchilla lanigera - long-tailed chinchilla) |
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SYN3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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SYN3 (Canis lupus familiaris - dog) |
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Syn3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SYN3 (Sus scrofa - pig) |
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SYN3 (Chlorocebus sabaeus - green monkey) |
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Syn3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Syn3
15313 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
D7Mgh9 |
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D7Rat40 |
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D7Rat216 |
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RH128273 |
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RH129267 |
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RH94615 |
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RH143027 |
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RH144261 |
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BI278238 |
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BF400160 |
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RH135110 |
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RH141014 |
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Timp3 |
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G45201 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_017109 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_063263102 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063263103 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063263104 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063263105 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC133425 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC136584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AC136645 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AF056704 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473960 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000037918 ⟹ ENSRNOP00000036740 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_017109 ⟹ NP_058805 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063263102 ⟹ XP_063119172 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063263103 ⟹ XP_063119173 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063263104 ⟹ XP_063119174 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063263105 ⟹ XP_063119175 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_058805 | (Get FASTA) | NCBI Sequence Viewer |
XP_063119172 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063119173 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063119174 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063119175 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAC24521 | (Get FASTA) | NCBI Sequence Viewer |
EDM17123 | (Get FASTA) | NCBI Sequence Viewer | |
EDM17124 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000036740 | ||
ENSRNOP00000036740.6 | |||
GenBank Protein | O70441 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_058805 ⟸ NM_017109 |
- UniProtKB: | O70441 (UniProtKB/Swiss-Prot), A6IFC2 (UniProtKB/TrEMBL), A0A096MIT7 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000036740 ⟸ ENSRNOT00000037918 |
RefSeq Acc Id: | XP_063119173 ⟸ XM_063263103 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70441 (UniProtKB/Swiss-Prot), A6IFC2 (UniProtKB/TrEMBL), A0A096MIT7 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063119172 ⟸ XM_063263102 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70441 (UniProtKB/Swiss-Prot), A6IFC2 (UniProtKB/TrEMBL), A0A096MIT7 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063119175 ⟸ XM_063263105 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70441 (UniProtKB/Swiss-Prot), A6IFC2 (UniProtKB/TrEMBL), A0A096MIT7 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063119174 ⟸ XM_063263104 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70441 (UniProtKB/Swiss-Prot), A6IFC2 (UniProtKB/TrEMBL), A0A096MIT7 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-O70441-F1-model_v2 | AlphaFold | O70441 | 1-579 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:3799 | AgrOrtholog |
BioCyc Gene | G2FUF-34667 | BioCyc |
Ensembl Genes | ENSRNOG00000026866 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000037918 | UniProtKB/TrEMBL |
ENSRNOT00000037918.6 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 3.30.1490.20 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
3.40.50.20 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
ATP-grasp fold, B domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | ATP_grasp_subdomain_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PreATP-grasp_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Synapsin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Synapsin_ATP-bd_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Synapsin_CS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Synapsin_P_site | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Synapsin_pre-ATP-grasp_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:29130 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NCBI Gene | 29130 | ENTREZGENE |
PANTHER | SYNAPSIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SYNAPSIN-3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Synapsin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Synapsin_C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Synapsin_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Syn3 | PhenoGen |
PRINTS | SYNAPSIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | SYNAPSIN_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SYNAPSIN_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000026866 | RatGTEx |
ENSRNOG00055021973 | RatGTEx | |
ENSRNOG00060026372 | RatGTEx | |
ENSRNOG00065024903 | RatGTEx | |
Superfamily-SCOP | Glutathione synthetase ATP-binding domain-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF52440 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A096MIT7 | ENTREZGENE, UniProtKB/TrEMBL |
A6IFC2 | ENTREZGENE, UniProtKB/TrEMBL | |
O70441 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2021-03-09 | Syn3 | synapsin III | LOC100910134 | synapsin-3-like | Data merged from RGD:6500248 | 737654 | PROVISIONAL |
2012-07-05 | LOC100910134 | synapsin-3-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2004-09-10 | Syn3 | synapsin III | synapsin 3 | Name updated | 1299863 | APPROVED | |
2002-06-10 | Syn3 | synapsin 3 | Name updated | 70585 | PROVISIONAL |
Note Type | Note | Reference |
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gene_function | binds ATP with high affinity and ADP with a lower affinity | 70029 |
gene_regulation | ATP binding is inhibited by Ca2+ | 70029 |