(-)-selegiline multiple interactions ISO RGD:733186 6480464 Selegiline inhibits the reaction [1 more ... CTD PMID:12880480 , PMID:15114628 (25R)-cholest-5-ene-3beta,26-diol increases expression ISO RGD:733186 6480464 27-hydroxycholesterol results in increased expression of SNCA mRNA, 27-hydroxycholesterol results in increased expression of SNCA protein CTD PMID:18841091 (3,4-dihydroxyphenyl)acetic acid decreases abundance ISO RGD:735748 6480464 SNCA protein mutant form results in decreased abundance of 3, 4-Dihydroxyphenylacetic Acid CTD PMID:18622040 (R)-lipoic acid multiple interactions ISO RGD:733186 6480464 [Acetylcarnitine co-treated with Thioctic Acid] inhibits the reaction [Rotenone results in increased expression of SNCA protein], Thioctic Acid inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:20414966 (R,R,R)-alpha-tocopherol multiple interactions ISO RGD:733186 6480464 alpha-Tocopherol inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:16439141 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline increases expression ISO RGD:733186 6480464 1 more ... CTD PMID:15114628 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline multiple interactions ISO RGD:733186 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [1 more ... CTD PMID:15114628 (S)-amphetamine decreases expression ISO RGD:735748 6480464 Dextroamphetamine results in decreased expression of SNCA mRNA CTD PMID:12558987 (S)-naringenin increases expression EXP 6480464 naringenin results in increased expression of SNCA mRNA CTD PMID:34655599 (S)-naringenin multiple interactions EXP 6480464 naringenin inhibits the reaction [Paraquat results in increased expression of SNCA mRNA] CTD PMID:34655599 (S)-nicotine increases expression ISO RGD:733186 6480464 Nicotine results in increased expression of SNCA mRNA CTD PMID:18247414 1,2-dimethylhydrazine increases expression ISO RGD:735748 6480464 1, 2-Dimethylhydrazine results in increased expression of SNCA mRNA CTD PMID:22206623 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:735748 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:15099020 more ... 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:735748 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:19857570 more ... 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:733186 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:19857570 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:733186 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:19857570 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 U 0126 promotes the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:19857570 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:19857570 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine affects response to substance ISO RGD:735748 6480464 SNCA affects the susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:12732244 , PMID:19032594 1-nitropyrene decreases expression ISO RGD:733186 6480464 1-nitropyrene results in decreased expression of SNCA mRNA CTD PMID:19041380 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of SNCA mRNA CTD PMID:12075121 17beta-estradiol multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] results in increased expression of SNCA mRNA CTD PMID:32741896 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735748 6480464 Tetrachlorodibenzodioxin results in increased expression of SNCA mRNA CTD PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SNCA mRNA CTD PMID:32109520 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:735748 6480464 2 more ... CTD PMID:16451863 , PMID:18550172 2-butoxyethanol increases expression ISO RGD:735748 6480464 n-butoxyethanol results in increased expression of SNCA mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression ISO RGD:733186 6480464 Lactic Acid results in increased expression of SNCA mRNA CTD PMID:30851411 2-methylcholine affects expression ISO RGD:733186 6480464 beta-methylcholine affects the expression of SNCA mRNA CTD PMID:21179406 2-naphthylamine increases expression ISO RGD:733186 6480464 2-Naphthylamine results in increased expression of SNCA mRNA CTD PMID:18247414 26-hydroxycholesterol increases expression ISO RGD:733186 6480464 27-hydroxycholesterol results in increased expression of SNCA mRNA, 27-hydroxycholesterol results in increased expression of SNCA protein CTD PMID:18841091 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of SNCA mRNA CTD PMID:28970181 3-hydroxybutyric acid multiple interactions ISO RGD:733186 6480464 3-Hydroxybutyric Acid inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone], 3-Hydroxybutyric Acid promotes the reaction [ursodoxicoltaurine inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone]] CTD PMID:16239214 3-hydroxybutyric acid multiple interactions ISO RGD:735748 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein]] more ... CTD PMID:36435477 3-methyladenine multiple interactions ISO RGD:733186 6480464 3-methyladenine inhibits the reaction [Rotenone results in decreased expression of SNCA mRNA], 3-methyladenine inhibits the reaction [Rotenone results in decreased expression of SNCA protein] CTD PMID:27133439 3-phenylprop-2-enal multiple interactions ISO RGD:735748 6480464 cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein] CTD PMID:31187328 4,4'-sulfonyldiphenol multiple interactions ISO RGD:733186 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in increased methylation of SNCA gene CTD PMID:31601247 4-hydroxyphenyl retinamide decreases expression ISO RGD:735748 6480464 Fenretinide results in decreased expression of SNCA mRNA CTD PMID:28973697 4-phenylbutyric acid multiple interactions ISO RGD:735748 6480464 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of SNCA protein], 4-phenylbutyric acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:17459145 , PMID:21372141 5,6,7,8-tetrahydrobiopterin increases abundance ISO RGD:733186 6480464 SNCA mutant form results in increased abundance of sapropterin CTD PMID:24148766 5-aza-2'-deoxycytidine decreases methylation ISO RGD:733186 6480464 Decitabine results in decreased methylation of SNCA promoter CTD PMID:23441691 5-aza-2'-deoxycytidine increases expression ISO RGD:733186 6480464 Decitabine results in increased expression of SNCA mRNA CTD PMID:19151715 , PMID:23441691 5-aza-2'-deoxycytidine affects expression ISO RGD:733186 6480464 Decitabine affects the expression of SNCA mRNA CTD PMID:23300844 5-aza-2'-deoxycytidine multiple interactions ISO RGD:733186 6480464 [Decitabine co-treated with trichostatin A] results in increased expression of SNCA mRNA CTD PMID:17891453 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SNCA mRNA CTD PMID:24780913 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of SNCA mRNA CTD PMID:24780913 8-Br-cAMP increases expression ISO RGD:733186 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SNCA mRNA CTD PMID:22079614 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SNCA mRNA CTD PMID:31881176 acetylsalicylic acid decreases expression ISO RGD:735748 6480464 Aspirin results in decreased expression of SNCA mRNA CTD PMID:21353610 acrolein affects binding ISO RGD:733186 6480464 Acrolein binds to SNCA protein CTD PMID:17690948 acrolein affects metabolic processing ISO RGD:733186 6480464 Acrolein affects the metabolism of SNCA protein CTD PMID:17690948 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [FGF2 protein results in increased expression of SNCA protein] CTD PMID:12562524 alcohol increases expression ISO RGD:733186 6480464 Alcohols results in increased expression of SNCA protein CTD PMID:18055133 all-trans-retinoic acid increases expression ISO RGD:733186 6480464 Tretinoin results in increased expression of SNCA mRNA CTD PMID:21934132 all-trans-retinol increases expression EXP 6480464 Vitamin A results in increased expression of SNCA protein CTD PMID:22274401 aluminium atom affects response to substance ISO RGD:733186 6480464 SNCA protein affects the susceptibility to Aluminum CTD PMID:23106139 aluminium(0) affects response to substance ISO RGD:733186 6480464 SNCA protein affects the susceptibility to Aluminum CTD PMID:23106139 ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of SNCA mRNA CTD PMID:16483693 ammonium chloride increases expression ISO RGD:733186 6480464 Ammonium Chloride results in increased expression of SNCA protein CTD PMID:23984410 anthocyanin decreases expression ISO RGD:733186 6480464 Anthocyanins results in decreased expression of SNCA protein CTD PMID:29976995 antimycin A increases expression ISO RGD:733186 6480464 Antimycin A results in increased expression of SNCA mRNA CTD PMID:33512557 antirheumatic drug decreases expression ISO RGD:733186 6480464 Antirheumatic Agents results in decreased expression of SNCA mRNA CTD PMID:24449571 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:28389404 apocynin multiple interactions EXP 6480464 acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased phosphorylation of SNCA protein] CTD PMID:29859868 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in decreased expression of SNCA mRNA CTD PMID:23912714 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SNCA protein CTD PMID:16174552 arsane affects methylation ISO RGD:733186 6480464 Arsenic affects the methylation of SNCA gene CTD PMID:25304211 arsane multiple interactions ISO RGD:733186 6480464 Arsenic promotes the reaction [SNCA protein binds to SNCA protein] CTD PMID:27413109 arsane increases expression ISO RGD:735748 6480464 Arsenic results in increased expression of SNCA protein CTD PMID:27413109 arsenic acid decreases expression EXP 6480464 arsenic acid results in decreased expression of SNCA CTD PMID:25639566 arsenic atom affects methylation ISO RGD:733186 6480464 Arsenic affects the methylation of SNCA gene CTD PMID:25304211 arsenic atom multiple interactions ISO RGD:733186 6480464 Arsenic promotes the reaction [SNCA protein binds to SNCA protein] CTD PMID:27413109 arsenic atom increases expression ISO RGD:735748 6480464 Arsenic results in increased expression of SNCA protein CTD PMID:27413109 arsenite(3-) increases phosphorylation ISO RGD:735748 6480464 arsenite results in increased phosphorylation of SNCA protein CTD PMID:33053406 arsenite(3-) increases methylation ISO RGD:733186 6480464 arsenite results in increased methylation of SNCA promoter CTD PMID:23974009 arsenous acid decreases expression ISO RGD:733186 6480464 Arsenic Trioxide results in decreased expression of SNCA mRNA CTD PMID:20458559 ATP multiple interactions ISO RGD:733186 6480464 GW8510 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate], SB 216763 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:24989254 ATP decreases abundance ISO RGD:733186 6480464 SNCA protein results in decreased abundance of Adenosine Triphosphate CTD PMID:24989254 atrazine increases expression EXP 6480464 Atrazine results in increased expression of SNCA mRNA CTD PMID:31185338 azoxystrobin increases expression ISO RGD:733186 6480464 azoxystrobin results in increased expression of SNCA mRNA CTD PMID:33512557 bafilomycin A1 multiple interactions ISO RGD:735748 6480464 [bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein CTD PMID:26031332 bafilomycin A1 increases expression ISO RGD:735748 6480464 bafilomycin A1 results in increased expression of SNCA protein CTD PMID:26031332 baicalein multiple interactions ISO RGD:735748 6480464 baicalein inhibits the reaction [Rotenone promotes the reaction [SNCA protein binds to SNCA protein]], baicalein inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:27425033 baicalein multiple interactions ISO RGD:733186 6480464 baicalein inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:27425033 BAPTA multiple interactions EXP 6480464 1 more ... CTD PMID:25433145 benzo[a]pyrene increases expression ISO RGD:733186 6480464 Benzo(a)pyrene results in increased expression of SNCA mRNA CTD PMID:18247414 benzo[a]pyrene multiple interactions ISO RGD:735748 6480464 Benzo(a)pyrene promotes the reaction [SNCA protein mutant form results in increased expression of and results in increased phosphorylation of SNCA protein], Benzo(a)pyrene promotes the reaction [SNCA protein mutant form results in increased expression of SNCA mRNA] CTD PMID:34332006 benzo[a]pyrene decreases expression ISO RGD:733186 6480464 Benzo(a)pyrene results in decreased expression of SNCA mRNA CTD PMID:34332006 benzo[a]pyrene affects methylation ISO RGD:733186 6480464 Benzo(a)pyrene affects the methylation of SNCA 5' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:733186 6480464 Benzo(a)pyrene results in increased methylation of SNCA promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:735748 6480464 Benzo(a)pyrene results in decreased expression of SNCA mRNA CTD PMID:17942131 more ... beta-naphthoflavone decreases expression ISO RGD:733186 6480464 beta-Naphthoflavone results in decreased expression of SNCA mRNA CTD PMID:32858204 bisphenol A decreases expression ISO RGD:735748 6480464 bisphenol A results in decreased expression of SNCA mRNA CTD PMID:26063408 , PMID:32156529 bisphenol A increases methylation ISO RGD:733186 6480464 bisphenol A results in increased methylation of SNCA gene CTD PMID:31601247 bisphenol A decreases expression ISO RGD:733186 6480464 bisphenol A results in decreased expression of SNCA protein CTD PMID:33376534 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SNCA mRNA CTD PMID:32145629 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SNCA mRNA CTD PMID:25181051 more ... bisphenol F decreases expression EXP 6480464 4, 4'-bisphenol F results in decreased expression of SNCA mRNA CTD PMID:26186136 bortezomib increases expression ISO RGD:733186 6480464 Bortezomib results in increased expression of SNCA mRNA CTD PMID:17895889 buta-1,3-diene increases expression ISO RGD:735748 6480464 1, 3-butadiene results in increased expression of SNCA mRNA CTD PMID:29038090 butanal increases expression ISO RGD:733186 6480464 butyraldehyde results in increased expression of SNCA mRNA CTD PMID:26079696 butanal increases methylation ISO RGD:733186 6480464 butyraldehyde results in increased methylation of SNCA gene CTD PMID:30002397 cadmium atom multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SNCA mRNA] CTD PMID:34816377 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of SNCA mRNA CTD PMID:34816377 cadmium dichloride increases expression ISO RGD:735748 6480464 Cadmium Chloride results in increased expression of SNCA mRNA CTD PMID:20061341 calcium atom multiple interactions EXP 6480464 omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] CTD PMID:17179863 calcium atom increases uptake EXP 6480464 SNCA protein results in increased uptake of Calcium CTD PMID:17179863 calcium(0) multiple interactions EXP 6480464 omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] CTD PMID:17179863 calcium(0) increases uptake EXP 6480464 SNCA protein results in increased uptake of Calcium CTD PMID:17179863 Calpeptin multiple interactions ISO RGD:733186 6480464 calpeptin inhibits the reaction [Paraquat results in increased expression of SNCA protein alternative form] CTD PMID:24509835 carbon nanotube decreases expression ISO RGD:735748 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO RGD:733186 6480464 CGP 52608 promotes the reaction [RORA protein binds to SNCA gene] CTD PMID:28238834 chlorogenic acid multiple interactions ISO RGD:735748 6480464 Chlorogenic Acid inhibits the reaction [Rotenone results in increased expression of SNCA protein], Chlorogenic Acid inhibits the reaction [Rotenone results in increased phosphorylation of SNCA protein] CTD PMID:36048341 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of SNCA mRNA CTD PMID:21968025 chlorpyrifos increases phosphorylation EXP 6480464 Chlorpyrifos results in increased phosphorylation of SNCA protein CTD PMID:29859868 chlorpyrifos multiple interactions ISO RGD:735748 6480464 Chlorpyrifos promotes the reaction [Paraquat results in increased expression of SNCA protein] CTD PMID:26884967 chlorpyrifos multiple interactions EXP 6480464 acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased phosphorylation of SNCA protein] CTD PMID:29859868 chlorpyrifos increases expression ISO RGD:735748 6480464 Chlorpyrifos results in increased expression of SNCA mRNA CTD PMID:37019170 cis-caffeic acid multiple interactions ISO RGD:733186 6480464 caffeic acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 cisplatin affects expression ISO RGD:733186 6480464 Cisplatin affects the expression of SNCA mRNA CTD PMID:23300844 cobalt dichloride decreases expression ISO RGD:733186 6480464 cobaltous chloride results in decreased expression of SNCA mRNA CTD PMID:19320972 cobalt dichloride affects folding ISO RGD:733186 6480464 cobaltous chloride affects the folding of SNCA protein CTD PMID:11553618 cocaine increases expression ISO RGD:733186 6480464 Cocaine results in increased expression of SNCA mRNA, Cocaine results in increased expression of SNCA protein CTD PMID:12684441 more ... cocaine affects expression ISO RGD:733186 6480464 Cocaine affects the expression of SNCA protein CTD PMID:19393250 coenzyme Q10 multiple interactions EXP 6480464 coenzyme Q10 inhibits the reaction [Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]] CTD PMID:21843543 coenzyme Q10 multiple interactions ISO RGD:735748 6480464 [coenzyme Q10 co-treated with Creatine] results in decreased expression of SNCA protein CTD PMID:19476553 coenzyme Q10 multiple interactions ISO RGD:733186 6480464 coenzyme Q10 inhibits the reaction [1 more ... CTD PMID:15114628 conduritol B epoxide multiple interactions ISO RGD:735748 6480464 [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which affects the localization of SNCA protein, [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein CTD PMID:19576930 conduritol B epoxide multiple interactions ISO RGD:733186 6480464 [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein CTD PMID:19576930 copper atom decreases expression EXP 6480464 Copper results in decreased expression of SNCA mRNA CTD PMID:22465980 copper atom multiple interactions ISO RGD:735748 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SNCA protein CTD PMID:36775208 copper atom multiple interactions ISO RGD:733186 6480464 Copper binds to and results in decreased folding of SNCA protein CTD PMID:22355530 copper atom increases expression EXP 6480464 Copper results in increased expression of SNCA mRNA CTD PMID:19781568 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of SNCA mRNA CTD PMID:22465980 copper(0) multiple interactions ISO RGD:735748 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SNCA protein CTD PMID:36775208 copper(0) multiple interactions ISO RGD:733186 6480464 Copper binds to and results in decreased folding of SNCA protein CTD PMID:22355530 copper(0) increases expression EXP 6480464 Copper results in increased expression of SNCA mRNA CTD PMID:19781568 copper(II) chloride affects folding ISO RGD:733186 6480464 cupric chloride affects the folding of SNCA protein CTD PMID:11553618 copper(II) sulfate multiple interactions ISO RGD:735748 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SNCA protein CTD PMID:36775208 Corynoxine B multiple interactions ISO RGD:733186 6480464 corynoxine B inhibits the reaction [manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]] CTD PMID:30578841 creatine multiple interactions ISO RGD:735748 6480464 [coenzyme Q10 co-treated with Creatine] results in decreased expression of SNCA protein CTD PMID:19476553 crocin-1 multiple interactions EXP 6480464 crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA], crocin inhibits the reaction [Malathion results in increased expression of SNCA protein] CTD PMID:35274200 curcumin multiple interactions ISO RGD:735748 6480464 [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of SNCA protein] more ... CTD PMID:31187328 , PMID:31820278 cyclosporin A decreases expression ISO RGD:735748 6480464 Cyclosporine results in decreased expression of SNCA mRNA CTD PMID:17942131 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [cypermethrin promotes the reaction [SNCA protein binds to SNCA protein]], Cyclosporine inhibits the reaction [cypermethrin results in increased expression of SNCA protein] CTD PMID:25370934 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of SNCA protein CTD PMID:25370934 cypermethrin increases expression ISO RGD:733186 6480464 cypermethrin results in increased expression of SNCA mRNA CTD PMID:27704156 cypermethrin multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [cypermethrin promotes the reaction [SNCA protein binds to SNCA protein]] more ... CTD PMID:25370934 cytarabine multiple interactions ISO RGD:733186 6480464 Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to ferrous chloride], Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron] CTD PMID:14535945 dabigatran multiple interactions EXP 6480464 Dabigatran inhibits the reaction [Rotenone results in increased expression of SNCA mRNA] CTD PMID:28585189 deguelin decreases expression ISO RGD:733186 6480464 deguelin results in decreased expression of SNCA mRNA CTD PMID:33512557 diarsenic trioxide decreases expression ISO RGD:733186 6480464 Arsenic Trioxide results in decreased expression of SNCA mRNA CTD PMID:20458559 dibenz[a,h]anthracene decreases expression ISO RGD:735748 6480464 1 more ... CTD PMID:26377693 dibenziodolium multiple interactions ISO RGD:735748 6480464 [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with diphenyleneiodonium] inhibits the reaction [SNCA protein mutant form results in increased susceptibility to Lipopolysaccharides] CTD PMID:21245015 dibutyl phthalate increases expression ISO RGD:735748 6480464 Dibutyl Phthalate results in increased expression of SNCA mRNA CTD PMID:21266533 dichloroacetic acid decreases expression ISO RGD:735748 6480464 Dichloroacetic Acid results in decreased expression of SNCA mRNA CTD PMID:28962523 dichlorvos multiple interactions EXP 6480464 coenzyme Q10 inhibits the reaction [Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]], Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein] CTD PMID:21843543 dichlorvos affects localization EXP 6480464 Dichlorvos affects the localization of SNCA protein CTD PMID:21073741 diclofenac increases expression ISO RGD:735748 6480464 Diclofenac results in increased expression of SNCA mRNA CTD PMID:26934552 dieldrin multiple interactions ISO RGD:735748 6480464 Dieldrin promotes the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:16809432 dieldrin multiple interactions EXP 6480464 SNCA protein promotes the reaction [Dieldrin results in increased expression of CASP3 protein] CTD PMID:15987830 dieldrin increases expression ISO RGD:735748 6480464 Dieldrin results in increased expression of SNCA protein CTD PMID:17291500 diethyldithiocarbamic acid increases expression EXP 6480464 Ditiocarb results in increased expression of SNCA protein CTD PMID:22874009 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of SNCA mRNA CTD PMID:17005392 dimethylarsinic acid decreases expression EXP 6480464 Cacodylic Acid results in decreased expression of SNCA CTD PMID:25639566 dioxygen multiple interactions ISO RGD:735748 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SNCA mRNA CTD PMID:30529165 dopamine increases response to substance ISO RGD:733186 6480464 SNCA gene mutant form results in increased susceptibility to Dopamine CTD PMID:15234109 dopamine decreases abundance ISO RGD:733186 6480464 SNCA protein results in decreased abundance of Dopamine CTD PMID:27026137 dopamine affects uptake ISO RGD:733186 6480464 SNCA protein affects the uptake of Dopamine CTD PMID:19032594 dopamine multiple interactions ISO RGD:733186 6480464 [SNCA protein affects the localization of SLC6A3 protein] which affects the uptake of Dopamine more ... CTD PMID:19032594 more ... dopamine increases abundance EXP 6480464 SNCA protein results in increased abundance of Dopamine CTD PMID:26075822 dopamine multiple interactions EXP 6480464 SNCA protein promotes the reaction [Rotenone results in decreased abundance of Dopamine] CTD PMID:26075822 dopamine decreases abundance ISO RGD:735748 6480464 SNCA protein mutant form results in decreased abundance of Dopamine CTD PMID:18622040 dopamine affects response to substance ISO RGD:735748 6480464 SNCA affects the susceptibility to Dopamine CTD PMID:19409267 dopamine affects abundance ISO RGD:733186 6480464 SNCA protein affects the abundance of Dopamine CTD PMID:17131421 , PMID:22319455 dopaminechrome (enol form) multiple interactions ISO RGD:733186 6480464 aminochrome 1 promotes the reaction [SNCA protein binds to SNCA protein], NQO1 protein inhibits the reaction [aminochrome 1 promotes the reaction [SNCA protein binds to SNCA protein]] CTD PMID:25634539 dorsomorphin multiple interactions ISO RGD:733186 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:735748 6480464 Doxorubicin results in decreased expression of SNCA mRNA CTD PMID:25896364 echinacoside multiple interactions ISO RGD:733186 6480464 echinacoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA] CTD PMID:27432061 empagliflozin multiple interactions EXP 6480464 empagliflozin inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:35654124 entacapone multiple interactions ISO RGD:733186 6480464 entacapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 entinostat increases expression ISO RGD:733186 6480464 entinostat results in increased expression of SNCA mRNA CTD PMID:27188386 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of SNCA mRNA CTD PMID:17920746 ethanol affects splicing ISO RGD:735748 6480464 Ethanol affects the splicing of SNCA mRNA CTD PMID:30319688 ethanol increases expression ISO RGD:735748 6480464 Ethanol results in increased expression of SNCA mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:733186 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of SNCA mRNA CTD PMID:29432896 fasudil multiple interactions EXP 6480464 fasudil inhibits the reaction [propionic acid results in increased expression of SNCA mRNA] CTD PMID:32481507 fenpyroximate increases response to substance ISO RGD:733186 6480464 SNCA protein results in increased susceptibility to fenpyroximate CTD PMID:16239214 ferrostatin-1 multiple interactions ISO RGD:735748 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:36435477 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of SNCA mRNA CTD PMID:18035473 folic acid decreases expression ISO RGD:735748 6480464 Folic Acid results in decreased expression of SNCA mRNA CTD PMID:25629700 fulvestrant multiple interactions ISO RGD:733186 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in increased methylation of SNCA gene CTD PMID:31601247 gallic acid multiple interactions ISO RGD:733186 6480464 Gallic Acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 gamma-tocopherol increases expression ISO RGD:735748 6480464 Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 geraniol multiple interactions ISO RGD:735748 6480464 geraniol inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:24103762 geraniol multiple interactions ISO RGD:733186 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of SNCA protein] more ... CTD PMID:27026137 , PMID:30141137 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]] CTD PMID:23353026 glutathione multiple interactions ISO RGD:733186 6480464 Dopamine inhibits the reaction [SNCA protein results in decreased abundance of Glutathione] more ... CTD PMID:27026137 , PMID:27424009 glutathione decreases abundance ISO RGD:733186 6480464 SNCA protein results in decreased abundance of Glutathione CTD PMID:27026137 , PMID:27424009 glutathione disulfide decreases abundance ISO RGD:733186 6480464 SNCA protein results in decreased abundance of Glutathione Disulfide CTD PMID:27424009 glyburide multiple interactions ISO RGD:735748 6480464 Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of SNCA protein] more ... CTD PMID:32375810 , PMID:34052309 glyphosate increases expression ISO RGD:733186 6480464 glyphosate results in increased expression of SNCA mRNA CTD PMID:31874349 GTP multiple interactions EXP 6480464 manganese chloride promotes the reaction [SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate]], SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]] CTD PMID:29289693 GTP affects binding EXP 6480464 SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate] CTD PMID:29289693 GW 3965 increases expression ISO RGD:733186 6480464 GW 3965 results in increased expression of SNCA mRNA, GW 3965 results in increased expression of SNCA protein CTD PMID:18841091 heptanal increases methylation ISO RGD:733186 6480464 heptanal results in increased methylation of SNCA gene CTD PMID:30002397 hexanal increases methylation ISO RGD:733186 6480464 n-hexanal results in increased methylation of SNCA gene CTD PMID:30002397 hydrogen peroxide increases expression ISO RGD:733186 6480464 Hydrogen Peroxide results in increased expression of SNCA mRNA alternative form CTD PMID:19857570 hydrogen peroxide affects response to substance ISO RGD:733186 6480464 SNCA protein affects the susceptibility to Hydrogen Peroxide CTD PMID:22319455 hydrogen peroxide multiple interactions ISO RGD:733186 6480464 [SNCA gene mutant form results in increased susceptibility to Hydrogen Peroxide] which results in increased metabolism of MEF2C protein CTD PMID:24290359 hydrogen peroxide increases response to substance ISO RGD:733186 6480464 SNCA gene mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:24290359 hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide promotes the reaction [manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]] CTD PMID:23353026 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of SNCA mRNA CTD PMID:23353026 hydroxyurea multiple interactions ISO RGD:733186 6480464 Hydroxyurea promotes the reaction [SNCA protein mutant form results in increased susceptibility to ferrous chloride], Hydroxyurea promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron] CTD PMID:14535945 iron atom multiple interactions ISO RGD:733186 6480464 Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron] more ... CTD PMID:14535945 , PMID:27324791 iron atom multiple interactions ISO RGD:735748 6480464 EUK-189 results in decreased susceptibility to [Iron co-treated with Paraquat co-treated with SNCA gene mutant form] CTD PMID:21039522 iron atom increases response to substance ISO RGD:733186 6480464 SNCA protein mutant form results in increased susceptibility to Iron CTD PMID:14535945 iron atom affects localization ISO RGD:733186 6480464 Iron affects the localization of SNCA protein CTD PMID:12401952 iron dichloride multiple interactions ISO RGD:733186 6480464 Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to ferrous chloride], Hydroxyurea promotes the reaction [SNCA protein mutant form results in increased susceptibility to ferrous chloride] CTD PMID:14535945 iron dichloride affects folding ISO RGD:733186 6480464 ferrous chloride affects the folding of SNCA protein CTD PMID:11553618 iron dichloride increases response to substance ISO RGD:733186 6480464 SNCA protein mutant form results in increased susceptibility to ferrous chloride CTD PMID:14535945 iron(0) multiple interactions ISO RGD:733186 6480464 Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron] more ... CTD PMID:14535945 , PMID:27324791 iron(0) affects localization ISO RGD:733186 6480464 Iron affects the localization of SNCA protein CTD PMID:12401952 iron(0) multiple interactions ISO RGD:735748 6480464 EUK-189 results in decreased susceptibility to [Iron co-treated with Paraquat co-treated with SNCA gene mutant form] CTD PMID:21039522 iron(0) increases response to substance ISO RGD:733186 6480464 SNCA protein mutant form results in increased susceptibility to Iron CTD PMID:14535945 iron(2+) sulfate (anhydrous) multiple interactions ISO RGD:733186 6480464 ferrous sulfate inhibits the reaction [SNCA protein results in decreased abundance of Glutathione] more ... CTD PMID:27424009 ivermectin decreases expression ISO RGD:733186 6480464 Ivermectin results in decreased expression of SNCA protein CTD PMID:32959892 L-ascorbic acid increases expression ISO RGD:735748 6480464 Ascorbic Acid results in increased expression of SNCA mRNA CTD PMID:15305145 lactacystin multiple interactions ISO RGD:733186 6480464 lactacystin promotes the reaction [SNCA protein mutant form binds to SNCA protein mutant form] CTD PMID:16584840 lactacystin decreases expression EXP 6480464 lactacystin results in decreased expression of SNCA protein CTD PMID:18818210 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of SNCA protein CTD PMID:22811615 lead nitrate affects localization ISO RGD:735748 6480464 lead nitrate affects the localization of SNCA protein CTD PMID:19542206 lead nitrate multiple interactions ISO RGD:735748 6480464 MT1 protein promotes the reaction [lead nitrate results in increased expression of SNCA mRNA] CTD PMID:19542206 lead nitrate increases expression ISO RGD:735748 6480464 lead nitrate results in increased expression of SNCA mRNA CTD PMID:19542206 lead(0) decreases expression ISO RGD:733186 6480464 Lead results in decreased expression of SNCA mRNA CTD PMID:19921347 lead(0) multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Lead results in increased expression of SNCA mRNA] CTD PMID:34816377 lead(0) increases expression EXP 6480464 Lead results in increased expression of SNCA mRNA CTD PMID:34816377 linsidomine increases expression ISO RGD:733186 6480464 linsidomine results in increased expression of SNCA protein CTD PMID:12880480 linsidomine multiple interactions ISO RGD:733186 6480464 Selegiline inhibits the reaction [linsidomine results in increased expression of SNCA protein] CTD PMID:12880480 lipoic acid multiple interactions ISO RGD:733186 6480464 [Acetylcarnitine co-treated with Thioctic Acid] inhibits the reaction [Rotenone results in increased expression of SNCA protein], Thioctic Acid inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:20414966 lipopolysaccharide multiple interactions ISO RGD:735748 6480464 [Lipopolysaccharides co-treated with SNCA protein] results in increased expression of IL1B mRNA, [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with diphenyleneiodonium] inhibits the reaction [SNCA protein mutant form results in increased susceptibility to Lipopolysaccharides] CTD PMID:21245015 , PMID:22122884 lipopolysaccharide increases response to substance ISO RGD:735748 6480464 SNCA protein mutant form results in increased susceptibility to Lipopolysaccharides CTD PMID:21245015 lipopolysaccharide increases metabolic processing ISO RGD:735748 6480464 Lipopolysaccharides results in increased metabolism of SNCA protein CTD PMID:21245015 lithium atom multiple interactions EXP 6480464 Lithium inhibits the reaction [Rotenone results in increased expression of and results in increased phosphorylation of SNCA protein] CTD PMID:25433145 lithium chloride increases expression ISO RGD:733186 6480464 Lithium Chloride results in increased expression of SNCA mRNA CTD PMID:23527032 lithium hydride multiple interactions EXP 6480464 Lithium inhibits the reaction [Rotenone results in increased expression of and results in increased phosphorylation of SNCA protein] CTD PMID:25433145 malathion increases expression EXP 6480464 Malathion results in increased expression of SNCA mRNA, Malathion results in increased expression of SNCA protein CTD PMID:35274200 malathion multiple interactions EXP 6480464 crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA] more ... CTD PMID:35274200 maneb multiple interactions ISO RGD:735748 6480464 [Maneb co-treated with Paraquat] results in increased phosphorylation of SNCA protein more ... CTD PMID:23017109 more ... maneb increases response to substance ISO RGD:733186 6480464 SNCA gene mutant form results in increased susceptibility to Maneb CTD PMID:24290359 maneb multiple interactions ISO RGD:733186 6480464 [Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]] which results in increased abundance of Nitric Oxide more ... CTD PMID:23017109 more ... manganese atom increases expression EXP 6480464 Manganese results in increased expression of SNCA mRNA CTD PMID:19781568 manganese atom multiple interactions ISO RGD:733186 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of SNCA protein more ... CTD PMID:24452053 more ... manganese atom multiple interactions EXP 6480464 Manganese affects the reaction [P4HB protein binds to SNCA protein], Manganese promotes the reaction [SNCA protein binds to and results in increased expression of SNCA protein] CTD PMID:24777576 manganese(0) increases expression EXP 6480464 Manganese results in increased expression of SNCA mRNA CTD PMID:19781568 manganese(0) multiple interactions ISO RGD:733186 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of SNCA protein more ... CTD PMID:24452053 more ... manganese(0) multiple interactions EXP 6480464 Manganese affects the reaction [P4HB protein binds to SNCA protein], Manganese promotes the reaction [SNCA protein binds to and results in increased expression of SNCA protein] CTD PMID:24777576 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of SNCA more ... CTD PMID:19276553 more ... manganese(II) chloride increases expression ISO RGD:733186 6480464 manganese chloride results in increased expression of SNCA mRNA, manganese chloride results in increased expression of SNCA protein CTD PMID:28986288 , PMID:30578841 manganese(II) chloride multiple interactions ISO RGD:733186 6480464 [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA more ... CTD PMID:24452053 more ... manganese(II) chloride multiple interactions EXP 6480464 Glutathione inhibits the reaction [manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]] more ... CTD PMID:23353026 more ... manganese(II) chloride affects folding ISO RGD:733186 6480464 manganese chloride affects the folding of SNCA protein CTD PMID:11553618 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Rotenone results in increased expression of SNCA protein], Melatonin inhibits the reaction [sodium arsenite promotes the reaction [SNCA protein binds to SNCA protein]] CTD PMID:17645694 , PMID:18289173 melatonin multiple interactions ISO RGD:735748 6480464 Melatonin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:34808223 mercury dibromide decreases expression ISO RGD:733186 6480464 mercuric bromide results in decreased expression of SNCA mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:733186 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCA mRNA CTD PMID:27188386 methamphetamine increases response to substance ISO RGD:733186 6480464 SNCA gene SNP results in increased susceptibility to Methamphetamine CTD PMID:15542733 methamphetamine increases response to substance ISO RGD:735748 6480464 SNCA protein results in increased susceptibility to Methamphetamine CTD PMID:32278788 methamphetamine multiple interactions ISO RGD:735748 6480464 [SNCA protein co-treated with Methamphetamine] results in decreased expression of NR4A2 protein more ... CTD PMID:31783120 more ... methamphetamine affects localization ISO RGD:733186 6480464 Methamphetamine affects the localization of SNCA protein modified form CTD PMID:32569805 methamphetamine affects localization ISO RGD:735748 6480464 Methamphetamine affects the localization of SNCA protein modified form CTD PMID:32569805 methamphetamine multiple interactions ISO RGD:733186 6480464 PRKN protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein] more ... CTD PMID:31059759 , PMID:31783120 methamphetamine increases expression ISO RGD:733186 6480464 Methamphetamine results in increased expression of SNCA protein CTD PMID:31059759 , PMID:31783120 methamphetamine multiple interactions EXP 6480464 CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein], Methamphetamine promotes the reaction [SNCA protein binds to SNCA protein] CTD PMID:25090657 , PMID:31059759 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of SNCA protein CTD PMID:17904249 more ... methamphetamine affects response to substance ISO RGD:735748 6480464 SNCA affects the susceptibility to Methamphetamine CTD PMID:12732244 methamphetamine increases expression ISO RGD:735748 6480464 Methamphetamine results in increased expression of SNCA protein CTD PMID:16181420 more ... methylmercury chloride decreases expression ISO RGD:735748 6480464 methylmercuric chloride results in decreased expression of SNCA mRNA CTD PMID:20061341 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of SNCA mRNA, cyanoginosin LR results in increased expression of SNCA protein CTD PMID:22430071 morphine increases expression EXP 6480464 Morphine results in increased expression of SNCA mRNA CTD PMID:15183518 N-acetyl-L-cysteine multiple interactions ISO RGD:733186 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:15114628 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SNCA mRNA] more ... CTD PMID:27613482 , PMID:34816377 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:733186 6480464 1-Methyl-4-phenylpyridinium promotes the reaction [SNCA protein binds to SNCA protein] more ... CTD PMID:12151787 more ... N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SNCA protein CTD PMID:31351185 , PMID:33204711 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:735748 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein]] more ... CTD PMID:31187328 , PMID:36435477 N-methyl-4-phenylpyridinium affects uptake ISO RGD:733186 6480464 SNCA protein affects the uptake of 1-Methyl-4-phenylpyridinium CTD PMID:19032594 N-methyl-4-phenylpyridinium increases expression ISO RGD:735748 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SNCA mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein CTD PMID:26056851 more ... N-methyl-4-phenylpyridinium decreases methylation ISO RGD:733186 6480464 1-Methyl-4-phenylpyridinium results in decreased methylation of SNCA promoter CTD PMID:23441691 N-methyl-4-phenylpyridinium increases expression ISO RGD:733186 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SNCA more ... CTD PMID:16678164 more ... N-methyl-4-phenylpyridinium increases response to substance ISO RGD:733186 6480464 SNCA protein mutant form results in increased susceptibility to 1-Methyl-4-phenylpyridinium more ... CTD PMID:12151787 more ... N-methyl-4-phenylpyridinium affects response to substance ISO RGD:735748 6480464 SNCA protein affects the susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:20079841 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 1-Methyl-4-phenylpyridinium promotes the reaction [SNCA protein binds to SNCA protein] more ... CTD PMID:17280646 more ... N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein, 1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein modified form CTD PMID:17280646 more ... N-methyl-4-phenylpyridinium affects response to substance ISO RGD:733186 6480464 SNCA mRNA affects the susceptibility to 1-Methyl-4-phenylpyridinium, SNCA protein affects the susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:17131421 more ... nickel atom decreases expression ISO RGD:733186 6480464 Nickel results in decreased expression of SNCA mRNA CTD PMID:24768652 , PMID:25583101 nickel sulfate increases expression ISO RGD:733186 6480464 nickel sulfate results in increased expression of SNCA mRNA CTD PMID:22714537 niclosamide increases expression ISO RGD:733186 6480464 Niclosamide results in increased expression of SNCA mRNA CTD PMID:36318118 nicotine increases expression ISO RGD:733186 6480464 Nicotine results in increased expression of SNCA mRNA CTD PMID:18247414 nicotinic acid multiple interactions ISO RGD:735748 6480464 [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of SNCA protein], Niacin inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:31820278 nitric oxide multiple interactions ISO RGD:733186 6480464 [Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]] which results in increased abundance of Nitric Oxide, [Paraquat promotes the reaction [SNCA gene mutant form results in increased susceptibility to Maneb]] which results in increased abundance of Nitric Oxide CTD PMID:24290359 nonanal increases methylation ISO RGD:733186 6480464 nonanal results in increased methylation of SNCA gene CTD PMID:30002397 Nookatone multiple interactions EXP 6480464 nootkatone inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:35833337 O-acetyl-L-carnitine multiple interactions ISO RGD:733186 6480464 [Acetylcarnitine co-treated with Thioctic Acid] inhibits the reaction [Rotenone results in increased expression of SNCA protein], Acetylcarnitine inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:20414966 octanal increases methylation ISO RGD:733186 6480464 caprylic aldehyde results in increased methylation of SNCA gene CTD PMID:30002397 omega-conotoxin GVIA multiple interactions EXP 6480464 omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] CTD PMID:17179863 oxidopamine increases expression ISO RGD:733186 6480464 Oxidopamine results in increased expression of SNCA mRNA alternative form CTD PMID:19857570 oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of SNCA protein CTD PMID:22016808 , PMID:31022188 oxidopamine increases response to substance ISO RGD:733186 6480464 SNCA protein mutant form results in increased susceptibility to Oxidopamine CTD PMID:16297908 ozone multiple interactions ISO RGD:735748 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SNCA mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of SNCA mRNA CTD PMID:34911549 paracetamol decreases expression ISO RGD:735748 6480464 Acetaminophen results in decreased expression of SNCA mRNA CTD PMID:17942131 paraquat multiple interactions ISO RGD:733186 6480464 [Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]] which results in increased abundance of Nitric Oxide more ... CTD PMID:15234109 more ... paraquat multiple interactions EXP 6480464 naringenin inhibits the reaction [Paraquat results in increased expression of SNCA mRNA] CTD PMID:34655599 paraquat increases expression EXP 6480464 Paraquat results in increased expression of SNCA mRNA CTD PMID:34655599 paraquat affects response to substance ISO RGD:733186 6480464 SNCA protein affects the susceptibility to Paraquat CTD PMID:24509835 paraquat increases expression ISO RGD:733186 6480464 Paraquat results in increased expression of SNCA mRNA more ... CTD PMID:17934957 more ... paraquat increases response to substance ISO RGD:733186 6480464 SNCA gene mutant form results in increased susceptibility to Paraquat, SNCA protein results in increased susceptibility to Paraquat CTD PMID:23934919 more ... paraquat affects response to substance ISO RGD:735748 6480464 SNCA gene affects the susceptibility to Paraquat CTD PMID:21039522 paraquat increases expression ISO RGD:735748 6480464 Paraquat results in increased expression of SNCA mRNA, Paraquat results in increased expression of SNCA protein CTD PMID:11707429 more ... paraquat multiple interactions ISO RGD:735748 6480464 [Maneb co-treated with Paraquat] results in increased phosphorylation of SNCA protein more ... CTD PMID:17879265 more ... paraquat decreases response to substance ISO RGD:733186 6480464 SNCA protein results in decreased susceptibility to Paraquat CTD PMID:12716914 , PMID:15234109 PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:23829299 pentanal increases expression ISO RGD:733186 6480464 pentanal results in increased expression of SNCA mRNA CTD PMID:26079696 pentanal increases methylation ISO RGD:733186 6480464 pentanal results in increased methylation of SNCA gene CTD PMID:30002397 permethrin increases expression ISO RGD:735748 6480464 Permethrin results in increased expression of SNCA protein CTD PMID:14575646 permethrin increases expression EXP 6480464 Permethrin results in increased expression of SNCA mRNA CTD PMID:31175960 phenobarbital affects expression ISO RGD:735748 6480464 Phenobarbital affects the expression of SNCA mRNA CTD PMID:23091169 potassium dichromate decreases expression ISO RGD:735748 6480464 Potassium Dichromate results in decreased expression of SNCA mRNA CTD PMID:23608068 proanthocyanidin decreases expression ISO RGD:733186 6480464 Proanthocyanidins results in decreased expression of SNCA protein CTD PMID:29976995 probucol multiple interactions ISO RGD:733186 6480464 Probucol inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone] CTD PMID:16239214 propanal increases expression ISO RGD:733186 6480464 propionaldehyde results in increased expression of SNCA mRNA CTD PMID:26079696 propanal increases methylation ISO RGD:733186 6480464 propionaldehyde results in increased methylation of SNCA gene CTD PMID:30002397 propionic acid increases expression EXP 6480464 propionic acid results in increased expression of SNCA mRNA CTD PMID:32481507 propionic acid multiple interactions EXP 6480464 fasudil inhibits the reaction [propionic acid results in increased expression of SNCA mRNA] CTD PMID:32481507 pyridaben increases response to substance ISO RGD:733186 6480464 SNCA protein results in increased susceptibility to pyridaben CTD PMID:16239214 pyrogallol multiple interactions ISO RGD:733186 6480464 Pyrogallol inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 quercetin multiple interactions ISO RGD:733186 6480464 Quercetin inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 rac-lactic acid increases expression ISO RGD:733186 6480464 Lactic Acid results in increased expression of SNCA mRNA CTD PMID:30851411 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of SNCA mRNA CTD PMID:16079270 reactive nitrogen species multiple interactions ISO RGD:733186 6480464 SNCA gene inhibits the reaction [DJR-1.1 mutant form promotes the reaction [manganese chloride results in increased abundance of Reactive Nitrogen Species]], SNCA gene inhibits the reaction [PDR-1 mutant form promotes the reaction [manganese chloride results in increased abundance of Reactive Nitrogen Species]] CTD PMID:24452053 reactive oxygen species multiple interactions ISO RGD:733186 6480464 ferrous sulfate promotes the reaction [SNCA protein results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:24452053 , PMID:27424009 reactive oxygen species increases abundance ISO RGD:733186 6480464 SNCA protein results in increased abundance of Reactive Oxygen Species CTD PMID:27424009 reserpine affects response to substance ISO RGD:735748 6480464 SNCA protein mutant form affects the susceptibility to Reserpine CTD PMID:18622040 resveratrol affects binding ISO RGD:733186 6480464 resveratrol binds to [SNCA protein binds to SNCA protein] CTD PMID:17597573 resveratrol multiple interactions EXP 6480464 Resveratrol affects the reaction [MIR141 mRNA affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SNCA protein]], Resveratrol inhibits the reaction [MIR141 mRNA inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SNCA protein]] CTD PMID:33204711 resveratrol multiple interactions ISO RGD:733186 6480464 BECN1 protein affects the reaction [resveratrol results in increased degradation of SNCA protein] CTD PMID:21778691 resveratrol increases degradation ISO RGD:733186 6480464 resveratrol results in increased degradation of SNCA protein CTD PMID:21778691 rifampicin multiple interactions EXP 6480464 Rifampin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein modified form], UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:17280646 , PMID:28132806 rifampicin increases sumoylation EXP 6480464 Rifampin results in increased sumoylation of SNCA protein CTD PMID:28132806 rotenone multiple interactions ISO RGD:733186 6480464 3-Hydroxybutyric Acid inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone] more ... CTD PMID:15280438 more ... rotenone increases phosphorylation ISO RGD:735748 6480464 Rotenone results in increased phosphorylation of SNCA protein CTD PMID:36048341 rotenone affects response to substance ISO RGD:733186 6480464 SNCA protein affects the susceptibility to Rotenone CTD PMID:22319455 , PMID:27585560 rotenone decreases expression ISO RGD:733186 6480464 Rotenone results in decreased expression of SNCA mRNA, Rotenone results in decreased expression of SNCA protein CTD PMID:27133439 rotenone decreases degradation EXP 6480464 Rotenone results in decreased degradation of SNCA protein CTD PMID:25433145 rotenone increases response to substance EXP 6480464 SNCA protein results in increased susceptibility to Rotenone CTD PMID:26075822 rotenone increases expression ISO RGD:735748 6480464 Rotenone results in increased expression of SNCA mRNA, Rotenone results in increased expression of SNCA protein CTD PMID:17459145 more ... rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SNCA protein CTD PMID:25430725 rotenone increases expression EXP 6480464 Rotenone results in increased expression of SNCA mRNA, Rotenone results in increased expression of SNCA protein CTD PMID:16219024 more ... rotenone increases expression ISO RGD:733186 6480464 Rotenone results in increased expression of SNCA mRNA alternative form, Rotenone results in increased expression of SNCA protein CTD PMID:12177198 more ... rotenone increases response to substance ISO RGD:733186 6480464 SNCA gene mutant form results in increased susceptibility to Rotenone more ... CTD PMID:12151787 more ... rotenone decreases response to substance ISO RGD:733186 6480464 SNCA protein results in decreased susceptibility to Rotenone CTD PMID:16239214 , PMID:17041725 rotenone increases ubiquitination EXP 6480464 Rotenone results in increased ubiquitination of SNCA protein CTD PMID:19626387 rotenone affects localization EXP 6480464 Rotenone affects the localization of SNCA protein, Rotenone affects the localization of SNCA protein modified form CTD PMID:11100151 more ... rotenone multiple interactions EXP 6480464 1 more ... CTD PMID:18289173 more ... rotenone affects localization ISO RGD:735748 6480464 Rotenone affects the localization of SNCA protein CTD PMID:20464527 rotenone multiple interactions ISO RGD:735748 6480464 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of SNCA protein] more ... CTD PMID:15099020 more ... rotenone affects localization ISO RGD:733186 6480464 Rotenone affects the localization of SNCA protein, Rotenone affects the localization of SNCA protein mutant form CTD PMID:19628769 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO RGD:733186 6480464 Buthionine Sulfoximine results in increased expression of SNCA protein CTD PMID:15114628 sapropterin increases abundance ISO RGD:733186 6480464 SNCA mutant form results in increased abundance of sapropterin CTD PMID:24148766 sarin decreases expression ISO RGD:733186 6480464 Sarin results in decreased expression of SNCA mRNA CTD PMID:19522546 sarin decreases expression EXP 6480464 Sarin results in decreased expression of SNCA protein CTD PMID:28973502 SB 431542 multiple interactions ISO RGD:733186 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide increases expression ISO RGD:733186 6480464 Silicon Dioxide analog results in increased expression of SNCA mRNA CTD PMID:25895662 silicon dioxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased expression of SNCA protein] CTD PMID:27613482 silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of SNCA protein CTD PMID:27613482 silver atom increases expression ISO RGD:735748 6480464 Silver results in increased expression of SNCA mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:735748 6480464 Silver results in increased expression of SNCA mRNA CTD PMID:27131904 sirolimus multiple interactions ISO RGD:733186 6480464 Sirolimus inhibits the reaction [Paraquat results in increased expression of SNCA protein] CTD PMID:32306690 sirtinol multiple interactions EXP 6480464 sirtinol affects the reaction [MIR141 mRNA affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SNCA protein]] CTD PMID:33204711 SKF 38393 affects localization EXP 6480464 2 more ... CTD PMID:25852303 sodium arsenite multiple interactions ISO RGD:733186 6480464 sodium arsenite promotes the reaction [SNCA protein binds to SNCA protein] CTD PMID:27413109 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of SNCA CTD PMID:25639566 sodium arsenite affects localization EXP 6480464 sodium arsenite affects the localization of SNCA protein CTD PMID:17681577 sodium arsenite multiple interactions EXP 6480464 ATG7 mutant form inhibits the reaction [sodium arsenite results in decreased expression of SNCA] more ... CTD PMID:17645694 , PMID:25639566 sodium arsenite increases expression ISO RGD:735748 6480464 sodium arsenite results in increased expression of SNCA protein CTD PMID:27413109 sodium arsenite increases expression ISO RGD:733186 6480464 sodium arsenite results in increased expression of SNCA mRNA CTD PMID:22714537 staurosporine multiple interactions ISO RGD:733186 6480464 [Staurosporine co-treated with Rotenone] promotes the reaction [SNCA protein binds to SNCA protein], SNCA protein affects the reaction [Staurosporine results in increased activity of SLC6A3 protein] CTD PMID:19032594 , PMID:19114014 stigmatellin A increases response to substance ISO RGD:733186 6480464 SNCA protein results in increased susceptibility to stigmatellin CTD PMID:16239214 tacrine decreases expression EXP 6480464 Tacrine results in decreased expression of SNCA mRNA CTD PMID:12832660 tamoxifen affects expression ISO RGD:733186 6480464 Tamoxifen affects the expression of SNCA mRNA CTD PMID:14699072 taurine multiple interactions ISO RGD:735748 6480464 Taurine inhibits the reaction [[Paraquat co-treated with Maneb] promotes the reaction [SNCA protein binds to SNCA protein]] CTD PMID:29568078 tauroursodeoxycholic acid multiple interactions ISO RGD:733186 6480464 3-Hydroxybutyric Acid promotes the reaction [ursodoxicoltaurine inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone]], ursodoxicoltaurine inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone] CTD PMID:16239214 telmisartan multiple interactions ISO RGD:735748 6480464 telmisartan inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23747572 temozolomide decreases expression ISO RGD:733186 6480464 Temozolomide results in decreased expression of SNCA mRNA CTD PMID:31758290 testosterone multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] results in increased expression of SNCA mRNA CTD PMID:32741896 testosterone enanthate affects expression ISO RGD:733186 6480464 testosterone enanthate affects the expression of SNCA mRNA CTD PMID:17440010 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SNCA mRNA CTD PMID:17805973 titanium dioxide increases expression ISO RGD:735748 6480464 titanium dioxide results in increased expression of SNCA mRNA CTD PMID:23557971 tocopherol increases expression ISO RGD:735748 6480464 Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 tolcapone multiple interactions ISO RGD:733186 6480464 tolcapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of SNCA mRNA CTD PMID:25729387 trans-caffeic acid multiple interactions ISO RGD:733186 6480464 caffeic acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 Tributyltin oxide decreases expression ISO RGD:735748 6480464 bis(tri-n-butyltin)oxide results in decreased expression of SNCA mRNA CTD PMID:17942131 trichloroethene multiple interactions EXP 6480464 Trichloroethylene results in increased expression of and results in increased phosphorylation of SNCA protein CTD PMID:33636387 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SNCA mRNA CTD PMID:33387578 trichostatin A multiple interactions ISO RGD:733186 6480464 [decitabine co-treated with trichostatin A] results in increased expression of SNCA mRNA CTD PMID:17891453 trichostatin A increases expression ISO RGD:733186 6480464 trichostatin A results in increased expression of SNCA mRNA CTD PMID:24935251 tungsten decreases expression ISO RGD:735748 6480464 Tungsten results in decreased expression of SNCA mRNA CTD PMID:30912803 valproic acid multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [Rotenone affects the localization of SNCA protein modified form], Valproic Acid inhibits the reaction [Rotenone results in increased ubiquitination of SNCA protein] CTD PMID:19626387 valproic acid increases expression EXP 13506279 valproic acid increases expression of Snca protein in rat cerebellum and frontal cortex RGD valproic acid increases expression ISO RGD:733186 6480464 Valproic Acid results in increased expression of SNCA mRNA CTD PMID:19101580 more ... valproic acid multiple interactions ISO RGD:733186 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SNCA mRNA CTD PMID:27188386 valproic acid affects expression ISO RGD:733186 6480464 Valproic Acid affects the expression of SNCA mRNA CTD PMID:25979313 Vinpocetine multiple interactions EXP 6480464 vinpocetine inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:36965781 ziram increases expression EXP 6480464 Ziram results in increased expression of SNCA protein CTD PMID:18818210
