Pfkfb2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pfkfb2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2) Rattus norvegicus
Analyze
Symbol: Pfkfb2
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
RGD ID: 3309
Description: Enables fructose-2,6-bisphosphate 2-phosphatase activity and kinase binding activity. Involved in several processes, including monocarboxylic acid metabolic process; positive regulation of glucokinase activity; and positive regulation of insulin secretion. Located in cytoplasm. Orthologous to human PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); PARTICIPATES IN fructose and mannose metabolic pathway; glycolysis pathway; INTERACTS WITH 2-ethoxyethanol; 2-methoxyethanol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart); 6-phosphofructo-2-kinase/fructose-26-bisphosphatase 2 (heart); 6-phosphofructo-2-kinase/fructose-26-bisphosphatase 2 (heart) (conflicting physical mapping); 6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme; fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase; PFK-2; PFK-2/FBPase-2; PFK/FBPase 2; RH2K
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21342,147,473 - 42,174,699 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1347,413,458 - 47,440,682 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01347,413,453 - 47,440,682 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01352,502,121 - 52,529,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,624,838 - 43,652,660 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11343,641,369 - 43,666,703 (-)NCBI
Celera1342,498,231 - 42,525,453 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
cytosol  (IBA)
nucleoplasm  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1299004   PMID:2837207   PMID:7612629   PMID:8889548   PMID:9464277   PMID:10095107   PMID:11069105   PMID:14623077   PMID:15896703   PMID:17553851   PMID:18199594   PMID:18710022  
PMID:19140452   PMID:23457334  


Genomics

Comparative Map Data
Pfkfb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21342,147,473 - 42,174,699 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1347,413,458 - 47,440,682 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01347,413,453 - 47,440,682 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01352,502,121 - 52,529,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,624,838 - 43,652,660 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11343,641,369 - 43,666,703 (-)NCBI
Celera1342,498,231 - 42,525,453 (-)NCBICelera
Cytogenetic Map13q13NCBI
PFKFB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1207,034,366 - 207,081,024 (+)EnsemblGRCh38hg38GRCh38
GRCh381207,053,063 - 207,081,027 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371207,226,620 - 207,254,372 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,293,243 - 205,320,991 (+)NCBINCBI36hg18NCBI36
Build 341203,615,037 - 203,634,707NCBI
Celera1180,478,124 - 180,505,909 (+)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1177,923,976 - 177,951,760 (+)NCBIHuRef
CHM1_11208,499,231 - 208,527,022 (+)NCBICHM1_1
Pfkfb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,616,780 - 130,656,990 (-)NCBIGRCm39mm39
GRCm39 Ensembl1130,616,919 - 130,656,990 (-)Ensembl
GRCm39 Ensembl1130,597,946 - 130,643,536 (-)Ensembl
GRCm381130,689,043 - 130,729,253 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,689,182 - 130,729,253 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,670,209 - 130,715,799 (-)EnsemblGRCm38mm10GRCm38
MGSCv371132,585,620 - 132,625,830 (-)NCBIGRCm37mm9NCBIm37
MGSCv361132,516,728 - 132,543,360 (-)NCBImm8
Celera1133,312,034 - 133,352,649 (-)NCBICelera
Cytogenetic Map1E4NCBI
Pfkfb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,574,450 - 42,598,109 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540642,573,210 - 42,601,994 (+)NCBIChiLan1.0ChiLan1.0
PFKFB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11186,934,229 - 186,962,001 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,934,446 - 186,961,995 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01182,655,487 - 182,683,881 (+)NCBIMhudiblu_PPA_v0panPan3
PFKFB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,193,519 - 6,220,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl76,196,656 - 6,218,397 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha75,756,664 - 5,783,300 (+)NCBI
ROS_Cfam_1.075,882,130 - 5,908,755 (+)NCBI
UMICH_Zoey_3.175,815,825 - 5,842,428 (+)NCBI
UNSW_CanFamBas_1.075,917,370 - 5,943,986 (+)NCBI
UU_Cfam_GSD_1.075,960,072 - 5,984,198 (+)NCBI
Pfkfb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,319,391 - 68,344,685 (-)NCBI
SpeTri2.0NW_0049365575,559,993 - 5,584,912 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFKFB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl967,680,507 - 67,709,522 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1967,681,786 - 67,716,921 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2974,061,189 - 74,080,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PFKFB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,277,692 - 22,306,057 (-)NCBI
ChlSab1.1 Ensembl2522,286,305 - 22,305,490 (-)Ensembl
Vero_WHO_p1.0NW_02366605522,919,723 - 22,948,072 (-)NCBI
Pfkfb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248074,420,577 - 4,442,842 (-)NCBI

Position Markers
D13Mgh12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,155,534 - 42,155,659 (+)MAPPERmRatBN7.2
Rnor_6.01347,421,515 - 47,421,639NCBIRnor6.0
Rnor_5.01352,510,179 - 52,510,303UniSTSRnor5.0
RGSC_v3.41343,633,492 - 43,633,617RGDRGSC3.4
RGSC_v3.41343,633,493 - 43,633,617UniSTSRGSC3.4
RGSC_v3.11343,647,535 - 43,647,660RGD
Celera1342,506,292 - 42,506,410UniSTS
RH 3.4 Map13110.5UniSTS
RH 3.4 Map13110.5RGD
RH 2.0 Map13322.5RGD
Cytogenetic Map13q24-q25UniSTS
RH144599  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,173,824 - 42,173,999 (+)MAPPERmRatBN7.2
Rnor_6.01347,439,808 - 47,439,982NCBIRnor6.0
Rnor_5.01352,528,472 - 52,528,646UniSTSRnor5.0
RGSC_v3.41343,651,786 - 43,651,960UniSTSRGSC3.4
Celera1342,524,579 - 42,524,753UniSTS
RH 3.4 Map13111.2UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map13q24-q25UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13147622148Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13901674250513953Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131409633059096330Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131409633059096330Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131444158250799665Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131444158251577031Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131981081464810814Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)132005247765052477Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132148248158537177Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132800833873008338Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132858445273584452Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133614753364868393Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134644457050799665Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:346
Count of miRNA genes:156
Interacting mature miRNAs:184
Transcripts:ENSRNOT00000005729, ENSRNOT00000037679, ENSRNOT00000050354, ENSRNOT00000050859, ENSRNOT00000067445
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 15 14 8 14 8 68 27 35 11
Low 1 28 43 33 5 33 8 11 6 8 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_080477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001840769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB040530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB040531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB040532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB040533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB041950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE113134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY312091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ422137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ422138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ438758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ438759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X61956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000005729   ⟹   ENSRNOP00000005729
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1347,415,351 - 47,440,682 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000037679   ⟹   ENSRNOP00000030819
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1347,413,458 - 47,440,682 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000050354   ⟹   ENSRNOP00000044506
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1347,415,351 - 47,440,682 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000050859   ⟹   ENSRNOP00000044027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1347,421,129 - 47,440,682 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000067445   ⟹   ENSRNOP00000060044
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1347,421,696 - 47,438,360 (-)Ensembl
RefSeq Acc Id: NM_001033964   ⟹   NP_001029136
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,147,478 - 42,174,699 (-)NCBI
Rnor_6.01347,413,458 - 47,440,682 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
RGSC_v3.41343,624,838 - 43,652,660 (-)RGD
Celera1342,498,231 - 42,525,453 (-)RGD
Sequence:
RefSeq Acc Id: NM_001033965   ⟹   NP_001029137
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,147,478 - 42,174,699 (-)NCBI
Rnor_6.01347,413,458 - 47,440,682 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
RGSC_v3.41343,624,838 - 43,652,660 (-)RGD
Celera1342,498,231 - 42,525,453 (-)RGD
Sequence:
RefSeq Acc Id: NM_080477   ⟹   NP_536725
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,147,478 - 42,174,699 (-)NCBI
Rnor_6.01347,413,458 - 47,440,682 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
RGSC_v3.41343,624,838 - 43,652,660 (-)RGD
Celera1342,498,231 - 42,525,453 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249706   ⟹   XP_006249768
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,173,610 (-)NCBI
Rnor_6.01347,416,584 - 47,439,557 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249707   ⟹   XP_006249769
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,173,761 (-)NCBI
Rnor_6.01347,416,584 - 47,439,693 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249708   ⟹   XP_006249770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,174,699 (-)NCBI
Rnor_6.01347,416,584 - 47,440,682 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249709   ⟹   XP_006249771
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,147,473 - 42,173,610 (-)NCBI
Rnor_6.01347,413,453 - 47,439,557 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249710   ⟹   XP_006249772
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,172,378 (-)NCBI
Rnor_6.01347,416,584 - 47,438,360 (-)NCBI
Rnor_5.01352,502,121 - 52,529,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769425   ⟹   XP_008767647
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,172,379 (-)NCBI
Rnor_6.01347,416,584 - 47,438,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090337   ⟹   XP_038946265
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,174,666 (-)NCBI
RefSeq Acc Id: XM_039090338   ⟹   XP_038946266
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,147,473 - 42,173,785 (-)NCBI
RefSeq Acc Id: XM_039090340   ⟹   XP_038946268
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,166,120 (-)NCBI
RefSeq Acc Id: XM_039090341   ⟹   XP_038946269
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,172,378 (-)NCBI
RefSeq Acc Id: XM_039090342   ⟹   XP_038946270
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,150,604 - 42,172,379 (-)NCBI
RefSeq Acc Id: XM_039090343   ⟹   XP_038946271
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,159,647 - 42,173,785 (-)NCBI
RefSeq Acc Id: XR_005492202
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21342,147,473 - 42,173,785 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001029136 (Get FASTA)   NCBI Sequence Viewer  
  NP_001029137 (Get FASTA)   NCBI Sequence Viewer  
  NP_536725 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249768 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249769 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249770 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249771 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249772 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767647 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946265 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946266 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946268 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946269 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946270 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946271 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41132 (Get FASTA)   NCBI Sequence Viewer  
  ACV65520 (Get FASTA)   NCBI Sequence Viewer  
  ACV65521 (Get FASTA)   NCBI Sequence Viewer  
  ACX42382 (Get FASTA)   NCBI Sequence Viewer  
  ACX42383 (Get FASTA)   NCBI Sequence Viewer  
  BAA96495 (Get FASTA)   NCBI Sequence Viewer  
  BAA96496 (Get FASTA)   NCBI Sequence Viewer  
  BAA96497 (Get FASTA)   NCBI Sequence Viewer  
  BAA96498 (Get FASTA)   NCBI Sequence Viewer  
  BAA96499 (Get FASTA)   NCBI Sequence Viewer  
  EDM09847 (Get FASTA)   NCBI Sequence Viewer  
  EDM09848 (Get FASTA)   NCBI Sequence Viewer  
  EDM09849 (Get FASTA)   NCBI Sequence Viewer  
  EDM09850 (Get FASTA)   NCBI Sequence Viewer  
  EDM09851 (Get FASTA)   NCBI Sequence Viewer  
  EDM09852 (Get FASTA)   NCBI Sequence Viewer  
  EDM09853 (Get FASTA)   NCBI Sequence Viewer  
  Q9JJH5 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_536725   ⟸   NM_080477
- Peptide Label: isoform c
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001029137   ⟸   NM_001033965
- Peptide Label: isoform a
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001029136   ⟸   NM_001033964
- Peptide Label: isoform b
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006249771   ⟸   XM_006249709
- Peptide Label: isoform X5
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006249770   ⟸   XM_006249708
- Peptide Label: isoform X2
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot),   R9PXY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249769   ⟸   XM_006249707
- Peptide Label: isoform X2
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot),   R9PXY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249768   ⟸   XM_006249706
- Peptide Label: isoform X2
- UniProtKB: Q9JJH5 (UniProtKB/Swiss-Prot),   R9PXY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249772   ⟸   XM_006249710
- Peptide Label: isoform X6
- UniProtKB: C9DRP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767647   ⟸   XM_008769425
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000060044   ⟸   ENSRNOT00000067445
RefSeq Acc Id: ENSRNOP00000044506   ⟸   ENSRNOT00000050354
RefSeq Acc Id: ENSRNOP00000044027   ⟸   ENSRNOT00000050859
RefSeq Acc Id: ENSRNOP00000030819   ⟸   ENSRNOT00000037679
RefSeq Acc Id: ENSRNOP00000005729   ⟸   ENSRNOT00000005729
RefSeq Acc Id: XP_038946266   ⟸   XM_039090338
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946265   ⟸   XM_039090337
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038946270   ⟸   XM_039090342
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038946269   ⟸   XM_039090341
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038946268   ⟸   XM_039090340
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038946271   ⟸   XM_039090343
- Peptide Label: isoform X9
Protein Domains
6PF2K

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3309 AgrOrtholog
Ensembl Genes ENSRNOG00000004162 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000005729 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000030819 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000044027 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000044506 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000060044 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005729 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000037679 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000050354 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000050859 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000067445 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 6Pfruct_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6Phosfructo_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_Pase_superF_clade-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PG/BPGM_mutase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24640 UniProtKB/Swiss-Prot
NCBI Gene 24640 ENTREZGENE
PANTHER PTHR10606 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 6PF2K UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  His_Phos_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pfkfb2 PhenoGen
PRINTS 6PFRUCTKNASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PG_MUTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PGAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53254 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C9DRP5_RAT UniProtKB/TrEMBL
  C9DRP6 ENTREZGENE, UniProtKB/TrEMBL
  D0EA88_RAT UniProtKB/TrEMBL
  D0EA89_RAT UniProtKB/TrEMBL
  F262_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  R9PXY6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q64297 UniProtKB/Swiss-Prot
  Q9JHL5 UniProtKB/Swiss-Prot
  Q9JJH4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2  Name updated 1299863 APPROVED
2002-06-10 Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization intracellular 61489
gene_process regulatory molecule that controls glycolysis in all eukaryotic tissues by integrating hormonal and metabolic signals