SRY (sex determining region Y) - Rat Genome Database

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Gene: SRY (sex determining region Y) Pan paniscus
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Symbol: SRY
Name: sex determining region Y
RGD ID: 329347687
Description: ENCODES a protein that exhibits DNA binding, bending (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN male gonad development (ortholog); male sex determination (ortholog); negative regulation of gene expression (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); 46,XX sex reversal 1 (ortholog); 46,XY sex reversal (ortholog); FOUND IN nucleus (ortholog); transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sex-determining region Y protein; TDF; Testis-determining factor
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2Y44,391,717 - 44,406,267 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1Y2,531,737 - 2,532,564 (-)NCBINHGRI_mPanPan1


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SRY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2Y44,391,717 - 44,406,267 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1Y2,531,737 - 2,532,564 (-)NCBINHGRI_mPanPan1
SRY
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y2,786,855 - 2,787,682 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblY2,786,855 - 2,787,682 (-)EnsemblGRCh38hg38GRCh38
GRCh37Y2,654,896 - 2,655,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36Y2,714,896 - 2,715,792 (-)NCBINCBI36Build 36hg18NCBI36
Build 34Y2,698,256 - 2,699,153NCBI
CeleraX88,844,082 - 88,844,978 (-)NCBICelera
Cytogenetic MapYp11.2NCBI
HuRefY7,900 - 8,786 (-)NCBIHuRef
T2T-CHM13v2.0Y2,463,695 - 2,464,522 (-)NCBIT2T-CHM13v2.0
Sry
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39Y2,662,471 - 2,663,658 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblY2,662,471 - 2,663,658 (-)EnsemblGRCm39 Ensembl
GRCm38Y2,662,471 - 2,663,658 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblY2,662,471 - 2,663,658 (-)EnsemblGRCm38mm10GRCm38
MGSCv37Y1,918,381 - 1,919,568 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36Y1,947,341 - 1,948,528 (-)NCBIMGSCv36mm8
CeleraY5,570,827 - 5,572,014 (+)NCBICelera
Cytogenetic MapYpterNCBI
Sry
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8Y465,260 - 465,772 (+)NCBIGRCr8
mRatBN7.2Y441,525 - 442,037 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_UtxY1,408,967 - 1,409,476 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0Y1,568,514 - 1,569,023 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0Y780,432 - 780,941 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0Y327,176 - 327,685 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblY327,166 - 329,299 (+)EnsemblRnor6.0rn6Rnor6.0
Cytogenetic MapYq11NCBI
SRY
(Canis lupus familiaris - dog)
No map positions available.
SRY
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblY40,484,990 - 40,485,700 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1Y40,484,990 - 40,485,700 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2Y279,587 - 280,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapYp12-p13NCBI
SRY
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X927,143 - 928,924 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX927,692 - 928,303 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_063602033   ⟹   XP_063458103
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2Y44,391,717 - 44,406,267 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063458103 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABM54238 (Get FASTA)   NCBI Sequence Viewer  
  CAA60141 (Get FASTA)   NCBI Sequence Viewer  
  Q28778 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_063458103   ⟸   XM_063602033
- UniProtKB: Q28778 (UniProtKB/Swiss-Prot),   A1YG13 (UniProtKB/Swiss-Prot)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH High mobility group box domain UniProtKB/Swiss-Prot
InterPro HMG_box_dom UniProtKB/Swiss-Prot
  HMG_box_dom_sf UniProtKB/Swiss-Prot
  SRY UniProtKB/Swiss-Prot
  SRY-related_HMG-box_TFs UniProtKB/Swiss-Prot
NCBI Gene SRY ENTREZGENE
PANTHER SEX-DETERMINING REGION Y PROTEIN UniProtKB/Swiss-Prot
  SOX TRANSCRIPTION FACTOR UniProtKB/Swiss-Prot
Pfam HMG_box UniProtKB/Swiss-Prot
PIRSF SRY UniProtKB/Swiss-Prot
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot
SMART HMG UniProtKB/Swiss-Prot
Superfamily-SCOP HMG-box UniProtKB/Swiss-Prot
UniProt A1YG13 ENTREZGENE
  Q28778 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A1YG13 UniProtKB/Swiss-Prot