USP18 (ubiquitin specific peptidase 18) - Rat Genome Database

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Gene: USP18 (ubiquitin specific peptidase 18) Pan paniscus
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Symbol: USP18
Name: ubiquitin specific peptidase 18
RGD ID: 329332500
Description: ENCODES a protein that exhibits ISG15-specific peptidase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); negative regulation of type I interferon-mediated signaling pathway (ortholog); regulation of inflammatory response (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); Aicardi-Goutieres syndrome (ortholog); Chronic Hepatitis C (ortholog); FOUND IN cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubl carboxyl-terminal hydrolase 18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22328,464,266 - 28,491,820 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,012,239 - 31,041,912 (+)NCBINHGRI_mPanPan1


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
USP18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22328,464,266 - 28,491,820 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,012,239 - 31,041,912 (+)NCBINHGRI_mPanPan1
USP18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,150,170 - 18,177,397 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,149,843 - 18,177,397 (+)EnsemblGRCh38hg38GRCh38
GRCh372218,632,937 - 18,660,164 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,012,758 - 17,040,164 (+)NCBINCBI36Build 36hg18NCBI36
Build 342217,007,311 - 17,034,714NCBI
Celera222,251,821 - 2,269,866 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef222,445,183 - 2,472,579 (+)NCBIHuRef
CHM1_12218,632,478 - 18,659,884 (+)NCBICHM1_1
T2T-CHM13v2.02218,822,080 - 18,849,307 (+)NCBIT2T-CHM13v2.0
Usp18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396121,222,865 - 121,247,876 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6121,222,865 - 121,247,876 (+)EnsemblGRCm39 Ensembl
GRCm386121,245,906 - 121,270,917 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6121,245,906 - 121,270,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv376121,195,924 - 121,220,935 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366121,211,575 - 121,236,536 (+)NCBIMGSCv36mm8
Celera6123,079,923 - 123,105,170 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.17NCBI
Usp18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84156,143,770 - 156,171,292 (+)NCBIGRCr8
mRatBN7.24154,471,634 - 154,499,154 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4154,471,592 - 154,499,144 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4160,737,808 - 160,765,283 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04156,521,289 - 156,548,767 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04155,144,802 - 155,172,259 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04153,812,312 - 153,834,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4153,805,993 - 153,834,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,901,558 - 220,922,139 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44157,692,720 - 157,694,884 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4143,317,875 - 143,338,351 (+)NCBICelera
Cytogenetic Map4q42NCBI
Usp18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554546,171,569 - 6,203,091 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554546,171,575 - 6,200,879 (+)NCBIChiLan1.0ChiLan1.0
USP18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12745,739,845 - 45,814,668 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha27868,159 - 943,927 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02746,107,395 - 46,183,398 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2746,106,886 - 46,183,378 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12746,041,070 - 46,116,807 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02746,008,145 - 46,083,815 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.027223,830 - 299,560 (-)NCBIUU_Cfam_GSD_1.0
Usp18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945109,829,924 - 109,854,928 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368071,090,882 - 1,114,770 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368071,090,928 - 1,116,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl570,183,308 - 70,229,572 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1570,183,321 - 70,227,990 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2572,536,548 - 72,595,957 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Usp18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247359,158,597 - 9,187,503 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_055105519   ⟹   XP_054961494
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,464,266 - 28,491,820 (+)NCBI
NHGRI_mPanPan12231,012,239 - 31,041,912 (+)NCBI
RefSeq Acc Id: XM_055105520   ⟹   XP_054961495
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,464,307 - 28,491,820 (+)NCBI
NHGRI_mPanPan12231,012,307 - 31,041,912 (+)NCBI
RefSeq Acc Id: XM_063603357   ⟹   XP_063459427
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,464,333 - 28,491,820 (+)NCBI
Protein Sequences
Protein RefSeqs XP_054961494 (Get FASTA)   NCBI Sequence Viewer  
  XP_054961495 (Get FASTA)   NCBI Sequence Viewer  
  XP_063459427 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_054961494   ⟸   XM_055105519
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054961495   ⟸   XM_055105520
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063459427   ⟸   XM_063603357
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
NCBI Gene USP18 ENTREZGENE