Oaz1 (ornithine decarboxylase antizyme 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Oaz1 (ornithine decarboxylase antizyme 1) Rattus norvegicus
Analyze
Symbol: Oaz1
Name: ornithine decarboxylase antizyme 1
RGD ID: 3219
Description: Enables enzyme binding activity and ornithine decarboxylase inhibitor activity. Involved in several processes, including cellular response to leptomycin B; cellular response to oxygen-glucose deprivation; and regulation of catabolic process. Located in cytoplasm and nucleus. Biomarker of brain ischemia. Human ortholog(s) of this gene implicated in coronary restenosis. Orthologous to human OAZ1 (ornithine decarboxylase antizyme 1); PARTICIPATES IN polyamine metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Oaz; ODC-Az; ODCAC; Ornithine decarboxylase antizyme
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Oaz1-ps1  
Allele / Splice: Oaz1-ps1
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,534,530 - 9,536,990 (-)NCBIGRCr8
mRatBN7.278,883,855 - 8,886,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,883,851 - 8,886,310 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,767,904 - 11,770,365 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,643,408 - 13,645,869 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,509,938 - 11,512,399 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,752,127 - 11,754,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,752,412 - 11,754,508 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,919,843 - 11,922,300 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,394,495 - 10,396,952 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,394,494 - 10,396,952 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBICelera
RH 3.4 Map740.6RGD
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA)
nucleus  (IBA,IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Regulation of ornithine decarboxylase and polyamine import by hypoxia in pulmonary artery endothelial cells. Babal P, etal., Am J Physiol Lung Cell Mol Physiol 2002 Apr;282(4):L840-6.
2. Structural elements of antizymes 1 and 2 are required for proteasomal degradation of ornithine decarboxylase. Chen H, etal., J Biol Chem. 2002 Nov 29;277(48):45957-61. Epub 2002 Sep 30.
3. Association of OAZ1 gene polymorphisms with subclinical and clinical vascular events. Dumont J, etal., Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2120-6. doi: 10.1161/ATVBAHA.107.150458. Epub 2007 Aug 30.
4. Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity. Gandre S, etal., Eur J Biochem 2002 Feb;269(4):1316-22.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia. Gubern C, etal., BMC Mol Biol. 2009 Jun 16;10:57. doi: 10.1186/1471-2199-10-57.
8. Structure, organization and expression of the mouse ornithine decarboxylase antizyme gene. Kankare K, etal., Biochem J 1997 Jun 15;324 ( Pt 3):807-13.
9. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
10. Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. Matsufuji S, etal., Cell 1995 Jan 13;80(1):51-60.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Feedback repression of polyamine transport is mediated by antizyme in mammalian tissue-culture cells. Mitchell JL, etal., Biochem J. 1994 Apr 1;299 ( Pt 1)(Pt 1):19-22. doi: 10.1042/bj2990019.
13. Identification of nuclear export signals in antizyme-1. Murai N, etal., J Biol Chem. 2003 Nov 7;278(45):44791-8. doi: 10.1074/jbc.M308059200. Epub 2003 Aug 26.
14. Evidence of a role for antizyme and antizyme inhibitor as regulators of human cancer. Olsen RR and Zetter BR, Mol Cancer Res. 2011 Oct;9(10):1285-93. doi: 10.1158/1541-7786.MCR-11-0178. Epub 2011 Aug 17.
15. Induction of immediate-early, ornithine decarboxylase and antizyme gene expression in the rat small intestine after transient ischaemia. Pujic Z, etal., Life Sci. 1996;58(25):2289-96. doi: 10.1016/0024-3205(96)00229-9.
16. GOA pipeline RGD automated data pipeline
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1572540   PMID:9445370   PMID:12477932   PMID:15277517   PMID:16120325   PMID:16128579   PMID:16916800   PMID:17900240   PMID:18508777   PMID:19349429   PMID:19449338   PMID:21861313  
PMID:24967154  


Genomics

Comparative Map Data
Oaz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,534,530 - 9,536,990 (-)NCBIGRCr8
mRatBN7.278,883,855 - 8,886,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,883,851 - 8,886,310 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,767,904 - 11,770,365 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,643,408 - 13,645,869 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,509,938 - 11,512,399 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,752,127 - 11,754,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,752,412 - 11,754,508 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,919,843 - 11,922,300 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,394,495 - 10,396,952 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,394,494 - 10,396,952 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBICelera
RH 3.4 Map740.6RGD
Cytogenetic Map7q11NCBI
OAZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,269,486 - 2,273,488 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,269,509 - 2,273,492 (+)EnsemblGRCh38hg38GRCh38
GRCh37192,269,485 - 2,273,487 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,220,520 - 2,224,487 (+)NCBINCBI36Build 36hg18NCBI36
Build 34192,220,519 - 2,224,487NCBI
Celera192,203,699 - 2,207,665 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef192,040,604 - 2,044,469 (+)NCBIHuRef
CHM1_1192,269,120 - 2,273,087 (+)NCBICHM1_1
T2T-CHM13v2.0192,243,130 - 2,247,132 (+)NCBIT2T-CHM13v2.0
Oaz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,662,490 - 80,665,124 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,662,516 - 80,665,124 (+)EnsemblGRCm39 Ensembl
GRCm381080,826,656 - 80,829,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,826,656 - 80,829,290 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,289,401 - 80,292,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,229,785 - 80,232,414 (+)NCBIMGSCv36mm8
Celera1081,845,454 - 81,848,088 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Oaz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,871,418 - 5,874,200 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,871,418 - 5,874,200 (-)NCBIChiLan1.0ChiLan1.0
OAZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2206,652,675 - 6,656,615 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,882,022 - 5,885,962 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0191,279,139 - 1,283,079 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1192,250,599 - 2,254,534 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,250,678 - 2,254,179 (+)Ensemblpanpan1.1panPan2
OAZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,769,317 - 56,770,921 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,769,319 - 56,770,930 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,564,657 - 56,567,316 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02057,502,449 - 57,505,111 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2057,502,449 - 57,505,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12056,554,504 - 56,557,154 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,039,687 - 57,042,333 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,240,093 - 57,242,753 (-)NCBIUU_Cfam_GSD_1.0
Oaz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,473,746 - 216,478,014 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,356,769 - 1,361,037 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,356,769 - 1,361,037 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OAZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,293,150 - 76,296,620 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,293,142 - 76,296,626 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2276,854,941 - 76,858,425 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OAZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,061,774 - 2,065,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl62,061,811 - 2,065,265 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660816,645,566 - 6,649,397 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Oaz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,617,727 - 6,620,402 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248286,617,342 - 6,620,466 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Oaz1
6 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:159
Interacting mature miRNAs:177
Transcripts:ENSRNOT00000026341
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat

Markers in Region
RH127959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,883,906 - 8,884,088 (+)MAPPERmRatBN7.2
mRatBN7.21137,084,624 - 37,084,806 (+)MAPPERmRatBN7.2
Rnor_6.01138,214,154 - 38,214,335NCBIRnor6.0
Rnor_6.0711,752,179 - 11,752,360NCBIRnor6.0
Rnor_5.01141,724,203 - 41,724,384UniSTSRnor5.0
Rnor_5.0711,919,894 - 11,920,075UniSTSRnor5.0
RGSC_v3.41137,729,459 - 37,729,640UniSTSRGSC3.4
RGSC_v3.4710,394,546 - 10,394,727UniSTSRGSC3.4
Celera77,068,029 - 7,068,210UniSTS
Celera1136,969,245 - 36,969,426UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map11q12UniSTS
RH142210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,885,265 - 8,885,434 (+)MAPPERmRatBN7.2
Rnor_6.0711,753,538 - 11,753,706NCBIRnor6.0
Rnor_5.0711,921,253 - 11,921,421UniSTSRnor5.0
RGSC_v3.4710,395,905 - 10,396,073UniSTSRGSC3.4
Celera77,069,388 - 7,069,556UniSTS
RH 3.4 Map740.6UniSTS
Cytogenetic Map7q11UniSTS
Oaz1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21137,084,727 - 37,084,884 (+)MAPPERmRatBN7.2
mRatBN7.278,884,009 - 8,884,166 (+)MAPPERmRatBN7.2
Rnor_6.0711,752,282 - 11,752,438NCBIRnor6.0
Rnor_6.01138,214,257 - 38,214,413NCBIRnor6.0
Rnor_5.01141,724,306 - 41,724,462UniSTSRnor5.0
Rnor_5.0711,919,997 - 11,920,153UniSTSRnor5.0
RGSC_v3.41137,729,562 - 37,729,718UniSTSRGSC3.4
RGSC_v3.4710,394,649 - 10,394,805UniSTSRGSC3.4
Celera77,068,132 - 7,068,288UniSTS
Celera1136,969,348 - 36,969,504UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map11q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001297557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC158783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D11372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000026341   ⟹   ENSRNOP00000026341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,883,860 - 8,886,310 (-)Ensembl
Rnor_6.0 Ensembl711,752,412 - 11,754,508 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110971   ⟹   ENSRNOP00000090905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,883,851 - 8,886,310 (-)Ensembl
RefSeq Acc Id: NM_001297557   ⟹   NP_001284486
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,534,530 - 9,536,990 (-)NCBI
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0711,752,127 - 11,754,587 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001301048   ⟹   NP_001287977
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,534,530 - 9,536,990 (-)NCBI
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0711,752,127 - 11,754,587 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139081   ⟹   NP_620781
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,534,530 - 9,536,990 (-)NCBI
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0711,752,127 - 11,754,587 (-)NCBI
Rnor_5.0711,919,843 - 11,922,300 (-)NCBI
RGSC_v3.4710,394,495 - 10,396,952 (-)RGD
Celera77,067,977 - 7,070,437 (-)NCBI
Sequence:
RefSeq Acc Id: NP_620781   ⟸   NM_139081
- Peptide Label: isoform 1
- UniProtKB: P54370 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001287977   ⟸   NM_001301048
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001284486   ⟸   NM_001297557
- Peptide Label: isoform 2
- Sequence:
Ensembl Acc Id: ENSRNOP00000026341   ⟸   ENSRNOT00000026341
Ensembl Acc Id: ENSRNOP00000090905   ⟸   ENSRNOT00000110971

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54370-F1-model_v2 AlphaFold P54370 1-227 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695016
Promoter ID:EPDNEW_R5526
Type:single initiation site
Name:Oaz1_1
Description:ornithine decarboxylase antizyme 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,754,582 - 11,754,642EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3219 AgrOrtholog
BioCyc Gene G2FUF-34971 BioCyc
Ensembl Genes ENSRNOG00000019459 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000110971 ENTREZGENE
Gene3D-CATH 3.40.630.60 UniProtKB/Swiss-Prot
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot
  ODC_AZ UniProtKB/Swiss-Prot
  ODC_AZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:25502 UniProtKB/Swiss-Prot
NCBI Gene 25502 ENTREZGENE
PANTHER PTHR10279 UniProtKB/Swiss-Prot
  PTHR10279:SF8 UniProtKB/Swiss-Prot
Pfam ODC_AZ UniProtKB/Swiss-Prot
PhenoGen Oaz1 PhenoGen
PROSITE ODC_AZ UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019459 RatGTEx
Superfamily-SCOP SSF55729 UniProtKB/Swiss-Prot
UniProt A0A8I6AEN8_RAT UniProtKB/TrEMBL
  A6K8F2_RAT UniProtKB/TrEMBL
  A6K8F4_RAT UniProtKB/TrEMBL
  A6K8F6_RAT UniProtKB/TrEMBL
  F1M8D8_RAT UniProtKB/TrEMBL
  OAZ1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27     Oaz1  ornithine decarboxylase antizyme 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Oaz1  ornithine decarboxylase antizyme 1  Oaz  Ornithine decarboxylase antizyme  Symbol and Name updated 625702 APPROVED
2002-06-10 Oaz  Ornithine decarboxylase antizyme      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation degradation involves functional ubiquitin-dependent proteolytic activity 727347