Slc3a2 (solute carrier family 3 member 2) - Rat Genome Database

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Gene: Slc3a2 (solute carrier family 3 member 2) Rattus norvegicus
Analyze
Symbol: Slc3a2
Name: solute carrier family 3 member 2
RGD ID: 3073
Description: Enables neutral L-amino acid transmembrane transporter activity. Involved in carboxylic acid transport; cellular response to glucose starvation; and response to muscle activity. Located in apical plasma membrane and basal plasma membrane. Biomarker of transitional cell carcinoma. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human SLC3A2 (solute carrier family 3 member 2); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4F2 cell-surface antigen heavy chain; 4F2hc; amino acid transporter heavy chain SLC3A2; antigen identified by monoclonal antibodies 4F2; Mdu1; solute carrier family 3 (activators of dibasic and neutral amino acid transport) member 2; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3, member 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21205,604,468 - 205,618,931 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,604,468 - 205,618,931 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,010,415 - 214,024,888 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,048,034 - 221,062,497 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,740,736 - 213,755,199 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,906,566 - 224,921,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,906,554 - 224,921,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,843,822 - 231,858,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,375,889 - 211,390,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,534,318 - 211,548,743 (-)NCBI
Celera1203,117,365 - 203,131,828 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
andrographolide  (ISO)
antimycin A  (ISO)
apigenin  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
Bardoxolone methyl  (ISO)
beauvericin  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bicalutamide  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
boron nitride  (ISO)
bosentan  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carmustine  (EXP)
celastrol  (ISO)
celecoxib  (ISO)
chloroacetaldehyde  (ISO)
chlorpromazine  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP,ISO)
curcumin  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
Dihydrocorynantheine  (EXP)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enniatin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP,ISO)
fenpyroximate  (ISO)
fipronil  (EXP)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-linolenic acid  (ISO)
gedunin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glutathione  (ISO)
Heptachlor epoxide  (ISO)
Hirsuteine  (EXP)
hydralazine  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
ifosfamide  (ISO)
indometacin  (EXP,ISO)
ionomycin  (ISO)
ivermectin  (ISO)
L-cystine  (ISO)
L-glutamic acid  (EXP)
L-methionine  (ISO)
lamivudine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP,ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
mercaptoethanol  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
metformin  (EXP)
methapyrilene  (EXP)
methotrexate  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
motexafin gadolinium  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
O-methyleugenol  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phorone  (EXP)
phosgene  (ISO)
phytoestrogen  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
procyanidin B1  (EXP)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thapsigargin  (EXP,ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
tioguanine  (EXP)
titanium dioxide  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP,ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)
zidovudine  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Site-directed mutagenesis of rabbit LAT1 at amino acids 219 and 234. Boado RJ, etal., J Neurochem. 2003 Mar;84(6):1322-31. doi: 10.1046/j.1471-4159.2003.01622.x.
2. CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway. Fei F, etal., Ann Surg Oncol. 2014 Dec;21(13):4359-68. doi: 10.1245/s10434-014-3816-1. Epub 2014 Aug 2.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Genetic variations in SLC3A2/CD98 gene as prognosis predictors in non-small cell lung cancer. Guo X, etal., Mol Carcinog. 2015 Jun;54 Suppl 1:E52-60. doi: 10.1002/mc.22167. Epub 2014 Apr 30.
6. Relationship between LAT1 expression and response to platinum-based chemotherapy in non-small cell lung cancer patients with postoperative recurrence. Kaira K, etal., Anticancer Res. 2011 Nov;31(11):3775-82.
7. l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms. Kaira K, etal., Cancer Sci. 2008 Dec;99(12):2380-6. doi: 10.1111/j.1349-7006.2008.00969.x. Epub 2008 Nov 17.
8. Expression of amino acid transporter (LAT1 and 4F2hc) in pulmonary pleomorphic carcinoma. Kaira K, etal., Hum Pathol. 2019 Feb;84:142-149. doi: 10.1016/j.humpath.2018.09.020. Epub 2018 Oct 6.
9. Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma. Kaira K, etal., Lung Cancer. 2009 Oct;66(1):120-6. doi: 10.1016/j.lungcan.2008.12.015. Epub 2009 Jan 26.
10. Clinicopathological significance of L-type amino acid transporter 1 (LAT1) expression in patients with adenoid cystic carcinoma. Kaira K, etal., Pathol Oncol Res. 2013 Oct;19(4):649-56. doi: 10.1007/s12253-013-9624-2. Epub 2013 Mar 21.
11. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). Kanai Y, etal., J Biol Chem 1998 Sep 11;273(37):23629-32.
12. Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinoma. Kume E, etal., Microscopy (Oxf). 2017 Jun 1;66(3):198-203. doi: 10.1093/jmicro/dfx008.
13. Expression of a system L neutral amino acid transporter at the blood-brain barrier. Matsuo H, etal., Neuroreport. 2000 Nov 9;11(16):3507-11. doi: 10.1097/00001756-200011090-00021.
14. Up-regulation of L-type amino acid transporter 1 (LAT1) in cultured rat retinal capillary endothelial cells in response to glucose deprivation. Matsuyama R, etal., Drug Metab Pharmacokinet. 2012;27(3):317-24. doi: 10.2133/dmpk.dmpk-11-rg-122. Epub 2011 Dec 20.
15. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
16. Induction of amino acid transporters expression by endurance exercise in rat skeletal muscle. Murakami T and Yoshinaga M, Biochem Biophys Res Commun. 2013 Oct 4;439(4):449-52. doi: 10.1016/j.bbrc.2013.08.094. Epub 2013 Sep 7.
17. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
18. Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models. Ohkame H, etal., J Surg Oncol. 2001 Dec;78(4):265-71; discussion 271-2. doi: 10.1002/jso.1165.
19. Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development. Park JC, etal., Anat Histol Embryol. 2004 Apr;33(2):119-24. doi: 10.1111/j.1439-0264.2003.00524.x.
20. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
21. Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function. Prasad PD, etal., Biochem Biophys Res Commun. 1999 Feb 16;255(2):283-8. doi: 10.1006/bbrc.1999.0206.
22. GOA pipeline RGD automated data pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
26. Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer. Toyoda M, etal., Br J Cancer. 2014 May 13;110(10):2506-13. doi: 10.1038/bjc.2014.178. Epub 2014 Apr 24.
27. SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer. Wang S, etal., Oncotarget. 2017 Jul 25;8(51):88586-88598. doi: 10.18632/oncotarget.19529. eCollection 2017 Oct 24.
28. Cloning and functional expression of a cDNA from rat jejunal epithelium encoding a protein (4F2hc) with system y+L amino acid transport activity. Yao SY, etal., Biochem J 1998 Mar 1;330 ( Pt 2):745-52.
Additional References at PubMed
PMID:8889548   PMID:12270127   PMID:15489334   PMID:16399997   PMID:17762180   PMID:19056867   PMID:19199708   PMID:19581412   PMID:19946888   PMID:20458337   PMID:21266579   PMID:22658674  
PMID:22871113   PMID:23376485   PMID:23533145   PMID:24534009   PMID:25063885   PMID:25468996   PMID:25998567   PMID:27570548   PMID:29476059   PMID:30867591   PMID:31505169  


Genomics

Comparative Map Data
Slc3a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21205,604,468 - 205,618,931 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,604,468 - 205,618,931 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,010,415 - 214,024,888 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,048,034 - 221,062,497 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,740,736 - 213,755,199 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,906,566 - 224,921,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,906,554 - 224,921,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,843,822 - 231,858,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,375,889 - 211,390,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,534,318 - 211,548,743 (-)NCBI
Celera1203,117,365 - 203,131,828 (-)NCBICelera
Cytogenetic Map1q43NCBI
SLC3A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,856,109 - 62,888,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,856,004 - 62,888,880 (+)EnsemblGRCh38hg38GRCh38
GRCh371162,623,581 - 62,656,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,380,094 - 62,412,929 (+)NCBINCBI36Build 36hg18NCBI36
Build 341162,380,149 - 62,412,840NCBI
Celera1159,946,914 - 59,979,926 (+)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,952,521 - 58,985,401 (+)NCBIHuRef
CHM1_11162,506,504 - 62,539,366 (+)NCBICHM1_1
T2T-CHM13v2.01162,845,504 - 62,878,241 (+)NCBIT2T-CHM13v2.0
Slc3a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,684,931 - 8,700,733 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,684,246 - 8,700,733 (-)EnsemblGRCm39 Ensembl
GRCm38198,706,882 - 8,723,369 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,706,882 - 8,723,369 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,781,372 - 8,797,859 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,773,927 - 8,780,919 (-)NCBIMGSCv36mm8
Celera198,465,148 - 8,481,790 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.44NCBI
Slc3a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599376,245 - 391,311 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955599376,133 - 391,434 (-)NCBIChiLan1.0ChiLan1.0
SLC3A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11165,123,352 - 65,156,538 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,212,395 - 58,241,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,565,664 - 61,594,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,565,680 - 61,594,579 (+)Ensemblpanpan1.1panPan2
SLC3A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,810,468 - 53,819,021 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,810,398 - 53,819,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,416,355 - 52,424,896 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,862,432 - 54,870,971 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,862,008 - 54,870,971 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11853,959,818 - 53,968,341 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,533,954 - 53,542,486 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,325,863 - 54,334,403 (-)NCBIUU_Cfam_GSD_1.0
Slc3a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,311,055 - 10,327,851 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936581424,801 - 441,592 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC3A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,892,089 - 8,919,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.128,892,071 - 8,919,070 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,245,279 - 8,273,049 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC3A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,011,351 - 11,050,494 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,008,120 - 11,050,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,363,791 - 108,393,242 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc3a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,301,584 - 1,315,707 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,301,866 - 1,314,598 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc3a2
41 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:112
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000025196
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1199368955224569684Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat

Markers in Region
D1Bda49  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21205,604,745 - 205,604,966 (+)MAPPERmRatBN7.2
Rnor_6.01224,906,844 - 224,907,064NCBIRnor6.0
Rnor_5.01231,844,100 - 231,844,320UniSTSRnor5.0
RGSC_v3.41211,376,162 - 211,376,382UniSTSRGSC3.4
Celera1203,117,643 - 203,117,863UniSTS
Cytogenetic Map1q43UniSTS
RH137032  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21205,604,568 - 205,604,748 (+)MAPPERmRatBN7.2
Rnor_6.01224,906,667 - 224,906,846NCBIRnor6.0
Rnor_5.01231,843,923 - 231,844,102UniSTSRnor5.0
RGSC_v3.41211,375,985 - 211,376,164UniSTSRGSC3.4
Celera1203,117,466 - 203,117,645UniSTS
RH 3.4 Map11516.9UniSTS
Cytogenetic Map1q43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000025196   ⟹   ENSRNOP00000025196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1205,604,468 - 205,618,931 (-)Ensembl
Rnor_6.0 Ensembl1224,906,554 - 224,921,092 (-)Ensembl
RefSeq Acc Id: NM_001271089   ⟹   NP_001258018
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21205,604,468 - 205,610,537 (-)NCBI
Rnor_6.01224,906,566 - 224,912,635 (-)NCBI
Rnor_5.01231,843,822 - 231,858,285 (-)NCBI
Celera1203,117,365 - 203,123,434 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019283   ⟹   NP_062156
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21205,604,468 - 205,618,931 (-)NCBI
Rnor_6.01224,906,566 - 224,921,029 (-)NCBI
Rnor_5.01231,843,822 - 231,858,285 (-)NCBI
RGSC_v3.41211,375,889 - 211,390,313 (-)RGD
Celera1203,117,365 - 203,131,828 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088488   ⟹   XP_038944416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21205,604,469 - 205,611,137 (-)NCBI
RefSeq Acc Id: XM_039088493   ⟹   XP_038944421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21205,604,469 - 205,610,748 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_062156   ⟸   NM_019283
- Peptide Label: isoform 1
- UniProtKB: A0A0H2UHQ0 (UniProtKB/TrEMBL),   A6HZS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258018   ⟸   NM_001271089
- Peptide Label: isoform 2
- UniProtKB: Q794F9 (UniProtKB/Swiss-Prot),   A6HZS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025196   ⟸   ENSRNOT00000025196
RefSeq Acc Id: XP_038944416   ⟸   XM_039088488
- Peptide Label: isoform X1
- UniProtKB: Q794F9 (UniProtKB/Swiss-Prot),   A6HZS2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944421   ⟸   XM_039088493
- Peptide Label: isoform X1
- UniProtKB: Q794F9 (UniProtKB/Swiss-Prot),   A6HZS2 (UniProtKB/TrEMBL)
Protein Domains
Glycosyl hydrolase family 13 catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q794F9-F1-model_v2 AlphaFold Q794F9 1-527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3073 AgrOrtholog
BioCyc Gene G2FUF-56522 BioCyc
Ensembl Genes ENSRNOG00000018487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025196 ENTREZGENE
  ENSRNOP00000025196.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025196 ENTREZGENE
  ENSRNOT00000025196.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycosidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599495 IMAGE-MGC_LOAD
InterPro Glyco_hydro_13_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLC3A2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLC3A2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:50567 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72480 IMAGE-MGC_LOAD
NCBI Gene 50567 ENTREZGENE
PANTHER 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46673 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Alpha-amylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLC3A2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc3a2 PhenoGen
SMART Aamy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glycosyl hydrolase domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 4F2_RAT UniProtKB/Swiss-Prot
  A0A0H2UHQ0 ENTREZGENE, UniProtKB/TrEMBL
  A6HZS0 ENTREZGENE, UniProtKB/TrEMBL
  A6HZS2 ENTREZGENE, UniProtKB/TrEMBL
  Q794F9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc3a2  solute carrier family 3 member 2  Slc3a2  solute carrier family 3 (amino acid transporter heavy chain), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-02 Slc3a2  solute carrier family 3 (amino acid transporter heavy chain), member 2  Slc3a2  solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc3a2  solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2    solute carrier family 3, member 2  Name updated 1299863 APPROVED
2002-06-10 Slc3a2  solute carrier family 3, member 2      Name updated 70584 APPROVED
2001-12-10 Slc3a2  solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2      Symbol and Name updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in jejunal epithelium 69887
gene_process involved in cell activation, cell growth and cell adhesion 634189
gene_protein composed of two subunits;80 kDa glycosylated heavy chain and 40 kDa nonglycosylated light chain 634189