Matr3 (matrin 3) - Rat Genome Database

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Gene: Matr3 (matrin 3) Rattus norvegicus
Analyze
Symbol: Matr3
Name: matrin 3
RGD ID: 3052
Description: Predicted to enable identical protein binding activity and miRNA binding activity. Predicted to be involved in activation of innate immune response and post-transcriptional regulation of gene expression. Predicted to act upstream of or within blastocyst formation; heart valve development; and ventricular septum development. Located in nuclear matrix. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 21. Orthologous to human MATR3 (matrin 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: matrin-3; nuclear scaffold protein P130/MAT3; P130/MAT3; snhg4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Matr3-ps1   Matr3-ps3  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,428,190 - 27,474,421 (+)NCBIGRCr8
mRatBN7.21827,154,098 - 27,193,212 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,163,714 - 27,193,166 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1827,291,153 - 27,320,586 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,053,486 - 28,082,679 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,388,370 - 27,417,564 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,351,691 - 28,390,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,361,283 - 28,390,717 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,074,345 - 28,103,874 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,171,639 - 28,215,659 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11828,221,884 - 28,242,302 (+)NCBI
Celera1826,897,382 - 26,926,742 (+)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3',5'-cyclic UMP  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
DDT  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
flavonoids  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
irinotecan  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
ozone  (ISO)
paracetamol  (EXP)
PCB138  (EXP)
pentachlorophenol  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
succimer  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear matrix  (IDA)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain. Belgrader P, etal., J Biol Chem 1991 May 25;266(15):9893-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Molecular properties and intracellular localization of rat liver nuclear scaffold protein P130. Hibino Y, etal., Biochim Biophys Acta. 2006 May;1759(5):195-207. Epub 2006 May 22.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:1575753   PMID:8250943   PMID:8357833   PMID:9111204   PMID:9524232   PMID:10860485   PMID:11112453   PMID:16396499   PMID:16641100   PMID:19946888   PMID:21771347   PMID:22082260  
PMID:22658674   PMID:22681889   PMID:22871113   PMID:24625528   PMID:25416956   PMID:25574029   PMID:27869233   PMID:28431233   PMID:28712728   PMID:28755400   PMID:29476059   PMID:30597036  
PMID:35736640  


Genomics

Comparative Map Data
Matr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,428,190 - 27,474,421 (+)NCBIGRCr8
mRatBN7.21827,154,098 - 27,193,212 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,163,714 - 27,193,166 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1827,291,153 - 27,320,586 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,053,486 - 28,082,679 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,388,370 - 27,417,564 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,351,691 - 28,390,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,361,283 - 28,390,717 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,074,345 - 28,103,874 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,171,639 - 28,215,659 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11828,221,884 - 28,242,302 (+)NCBI
Celera1826,897,382 - 26,926,742 (+)NCBICelera
Cytogenetic Map18p11NCBI
MATR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385139,274,101 - 139,331,677 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5139,293,674 - 139,331,677 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl5139,273,752 - 139,331,671 (+)EnsemblGRCh38hg38GRCh38
GRCh375138,609,790 - 138,667,366 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,637,691 - 138,694,029 (+)NCBINCBI36Build 36hg18NCBI36
Build 345138,657,253 - 138,694,023NCBI
Celera5134,731,161 - 134,789,067 (+)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5133,798,796 - 133,857,165 (+)NCBIHuRef
CHM1_15138,042,040 - 138,099,954 (+)NCBICHM1_1
T2T-CHM13v2.05139,800,176 - 139,857,743 (+)NCBIT2T-CHM13v2.0
Matr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,686,462 - 35,724,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,695,191 - 35,726,888 (+)EnsemblGRCm39 Ensembl
GRCm381835,562,158 - 35,592,045 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,562,138 - 35,593,835 (+)EnsemblGRCm38mm10GRCm38
MGSCv371835,721,812 - 35,751,699 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361835,688,242 - 35,717,383 (+)NCBIMGSCv36mm8
Celera1836,018,404 - 36,048,039 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.14NCBI
Matr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,213,503 - 1,269,746 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554181,213,503 - 1,269,755 (-)NCBIChiLan1.0ChiLan1.0
MATR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24134,560,617 - 134,598,387 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15132,700,169 - 132,737,940 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05134,664,893 - 134,702,566 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15140,788,667 - 140,825,064 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5140,788,709 - 140,825,064 (+)Ensemblpanpan1.1panPan2
MATR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,736,728 - 26,790,449 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,758,261 - 26,790,449 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1125,527,245 - 25,559,143 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01127,616,211 - 27,648,180 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1127,594,256 - 27,648,043 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11126,323,723 - 26,355,841 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01126,145,651 - 26,177,531 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01126,810,878 - 26,842,761 (+)NCBIUU_Cfam_GSD_1.0
Matr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,192,756 - 153,239,429 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365318,385,743 - 8,420,836 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365318,385,919 - 8,418,753 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MATR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,179,566 - 141,231,015 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12141,179,515 - 141,230,259 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,010,375 - 147,060,861 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MATR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12341,955,451 - 41,992,280 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2341,969,459 - 41,994,233 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603435,898,083 - 35,935,039 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Matr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,115,544 - 32,146,921 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474332,086,821 - 32,147,079 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Matr3
153 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:88
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000026949
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 57 41 19 41 8 10 74 35 41 11 8
Low 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB205483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC135285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC420149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000026949   ⟹   ENSRNOP00000026949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,163,714 - 27,193,166 (+)Ensembl
Rnor_6.0 Ensembl1828,361,283 - 28,390,696 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083993   ⟹   ENSRNOP00000073436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1828,370,085 - 28,390,717 (+)Ensembl
RefSeq Acc Id: NM_019149   ⟹   NP_062022
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,824 - 27,467,257 (+)NCBI
mRatBN7.21827,163,729 - 27,193,164 (+)NCBI
Rnor_6.01828,361,283 - 28,390,716 (+)NCBI
Rnor_5.01828,074,345 - 28,103,874 (+)NCBI
RGSC_v3.41828,171,639 - 28,215,659 (+)RGD
Celera1826,897,382 - 26,926,742 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254534   ⟹   XP_006254596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,730 - 27,467,258 (+)NCBI
mRatBN7.21827,163,644 - 27,193,212 (+)NCBI
Rnor_6.01828,361,227 - 28,390,764 (+)NCBI
Rnor_5.01828,074,345 - 28,103,874 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600886   ⟹   XP_017456375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,428,190 - 27,467,258 (+)NCBI
mRatBN7.21827,154,098 - 27,193,212 (+)NCBI
Rnor_6.01828,351,691 - 28,390,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600887   ⟹   XP_017456376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,959 - 27,467,258 (+)NCBI
mRatBN7.21827,163,891 - 27,193,212 (+)NCBI
Rnor_6.01828,361,365 - 28,390,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277175   ⟹   XP_063133245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,730 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277176   ⟹   XP_063133246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,837 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277177   ⟹   XP_063133247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,185 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277178   ⟹   XP_063133248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,899 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277179   ⟹   XP_063133249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,185 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277180   ⟹   XP_063133250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,428,191 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277181   ⟹   XP_063133251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,886 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277182   ⟹   XP_063133252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,868 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277183   ⟹   XP_063133253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,183 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277184   ⟹   XP_063133254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,183 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277185   ⟹   XP_063133255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,758 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277186   ⟹   XP_063133256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,784 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277187   ⟹   XP_063133257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,734 - 27,474,421 (+)NCBI
RefSeq Acc Id: NP_062022   ⟸   NM_019149
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254596   ⟸   XM_006254534
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456375   ⟸   XM_017600886
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456376   ⟸   XM_017600887
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000026949   ⟸   ENSRNOT00000026949
RefSeq Acc Id: ENSRNOP00000073436   ⟸   ENSRNOT00000083993
RefSeq Acc Id: XP_063133250   ⟸   XM_063277180
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133245   ⟸   XM_063277175
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133257   ⟸   XM_063277187
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063133255   ⟸   XM_063277185
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063133256   ⟸   XM_063277186
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063133246   ⟸   XM_063277176
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133252   ⟸   XM_063277182
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063133251   ⟸   XM_063277181
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133248   ⟸   XM_063277178
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133254   ⟸   XM_063277184
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063133253   ⟸   XM_063277183
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063133247   ⟸   XM_063277177
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133249   ⟸   XM_063277179
- Peptide Label: isoform X1
Protein Domains
Matrin-type   RRM   U1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P43244-F1-model_v2 AlphaFold P43244 1-845 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700708
Promoter ID:EPDNEW_R11231
Type:initiation region
Name:Matr3_1
Description:matrin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01828,361,286 - 28,361,346EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3052 AgrOrtholog
BioCyc Gene G2FUF-7909 BioCyc
Ensembl Genes ENSRNOG00000019875 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026949.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921221 IMAGE-MGC_LOAD
InterPro MATR3_RRM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATR3_RRM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Matrin/U1-C_Znf_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72856 IMAGE-MGC_LOAD
NCBI Gene 29150 ENTREZGENE
PANTHER MATRIN 3/NUCLEAR PROTEIN 220-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATRIN-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Matr3 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_MATRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019875 RatGTEx
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_U1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217434
UniProt A0A0G2JSR7 ENTREZGENE, UniProtKB/TrEMBL
  A6J2X6 ENTREZGENE, UniProtKB/TrEMBL
  B5DEM0_RAT UniProtKB/TrEMBL
  MATR3_RAT UniProtKB/Swiss-Prot
  O35833 ENTREZGENE
  P43244 ENTREZGENE
  Q5DVW1 ENTREZGENE
  Q6P6H1_RAT UniProtKB/TrEMBL
UniProt Secondary O35833 UniProtKB/Swiss-Prot
  Q5DVW1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Matr3  matrin 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains a highly acidic domain and a putative nuclear targeting signal sequence 69882