Mapk3 (mitogen activated protein kinase 3) - Rat Genome Database

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Gene: Mapk3 (mitogen activated protein kinase 3) Rattus norvegicus
Symbol: Mapk3
Name: mitogen activated protein kinase 3
RGD ID: 3046
Description: Enables ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including MAPK cascade; arachidonic acid metabolic process; and decidualization. Located in caveola; cytoplasm; and nucleoplasm. Part of protein-containing complex. Used to study several diseases, including alcohol dependence; cocaine abuse; drug dependence (multiple); gastric ulcer; and middle cerebral artery infarction. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in Parkinson's disease; carcinoma (multiple); and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ceramide signaling pathway; endothelin signaling pathway; INTERACTS WITH (+)-catechin; (+)-dihydromyricetin; (+)-pilocarpine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Erk-1; ERK1; ERT2; Esrk1; extracellular signal-regulated kinase 1; extracellular-signal-regulated kinase 1; insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAPK 1; MAPK 3; MAPK1; microtubule-associated protein 2 kinase; mitogen activated kinase 3; mitogen-activated 3; mitogen-activated 3 (MAP kinase 3, p44); mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MNK1; p44; p44-ERK1; p44-MAPK; p44erk1; p44mapk; Prkm3; Protein kinase mitogen activated 3 (extracellular-signal-regulated kinase 1 ERK1); Protein kinase, mitogen activated 3 (extracellular-signal-regulated kinase 1, ERK1)
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
GRCr81190,797,189 - 190,803,411 (+)NCBIGRCr8
mRatBN7.21181,366,646 - 181,372,863 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,366,637 - 181,372,863 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,717,952 - 189,724,168 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,904,026 - 196,910,242 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,571,369 - 189,577,596 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,192,773 - 198,198,975 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,192,773 - 198,198,975 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,172,641 - 205,178,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,935,044 - 185,941,245 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,084,924 - 186,091,127 (+)NCBI
Celera1179,022,318 - 179,028,386 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)