Man2b1 (mannosidase, alpha, class 2B, member 1) - Rat Genome Database

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Gene: Man2b1 (mannosidase, alpha, class 2B, member 1) Rattus norvegicus
Analyze
Symbol: Man2b1
Name: mannosidase, alpha, class 2B, member 1
RGD ID: 3039
Description: Enables D-mannose binding activity and alpha-mannosidase activity. Predicted to be involved in oligosaccharide catabolic process and protein modification process. Predicted to act upstream of or within learning or memory and mannose metabolic process. Predicted to be located in extracellular space and nucleoplasm. Predicted to be active in lysosomal lumen. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Orthologous to human MAN2B1 (mannosidase alpha class 2B member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lysosomal alpha-mannosidase; Manb; mannosidase 2, alpha B1; Mannosidase alpha B lysosomal; Mannosidase, alpha B, lysosomal; MGC72561; similar to mannosidase 2, alpha B1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81939,959,964 - 39,979,299 (-)NCBIGRCr8
mRatBN7.21923,055,092 - 23,074,398 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,055,097 - 23,074,389 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1929,877,660 - 29,896,989 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,532,022 - 30,551,353 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,754,699 - 32,774,034 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01926,196,797 - 26,216,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,196,837 - 26,216,267 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01937,172,434 - 37,191,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,711,378 - 24,730,659 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11924,716,204 - 24,735,485 (-)NCBI
Celera1922,613,060 - 22,632,343 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning, expression, purification, and characterization of the murine lysosomal acid alpha-mannosidase. Merkle RK, etal., Biochim Biophys Acta 1997 Aug 29;1336(2):132-46.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Alterations in certain lysosomal glycohydrolases and cathepsins in rats on dexamethasone administration. Rajashree S and Puvanakrishnan R, Mol Cell Biochem. 1996 Jan 26;154(2):165-70.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis. Sleat DE, etal., J Biol Chem. 1996 Aug 9;271(32):19191-8.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8910458   PMID:9355733   PMID:10400983   PMID:16014715   PMID:23376485   PMID:23533145   PMID:25645918   PMID:25797317  


Genomics

Comparative Map Data
Man2b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81939,959,964 - 39,979,299 (-)NCBIGRCr8
mRatBN7.21923,055,092 - 23,074,398 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,055,097 - 23,074,389 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1929,877,660 - 29,896,989 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,532,022 - 30,551,353 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,754,699 - 32,774,034 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01926,196,797 - 26,216,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,196,837 - 26,216,267 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01937,172,434 - 37,191,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,711,378 - 24,730,659 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11924,716,204 - 24,735,485 (-)NCBI
Celera1922,613,060 - 22,632,343 (-)NCBICelera
Cytogenetic Map19q11NCBI
MAN2B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,646,512 - 12,666,742 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,643,831 - 12,666,742 (-)EnsemblGRCh38hg38GRCh38
GRCh371912,757,326 - 12,777,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,618,322 - 12,638,828 (-)NCBINCBI36Build 36hg18NCBI36
Build 341912,618,321 - 12,638,828NCBI
Celera1912,647,038 - 12,667,305 (-)NCBICelera
Cytogenetic Map19p13.13NCBI
HuRef1912,330,278 - 12,350,679 (-)NCBIHuRef
CHM1_11912,757,826 - 12,778,096 (-)NCBICHM1_1
T2T-CHM13v2.01912,771,019 - 12,791,240 (-)NCBIT2T-CHM13v2.0
Man2b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,809,941 - 85,824,215 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl885,809,899 - 85,824,911 (+)EnsemblGRCm39 Ensembl
GRCm38885,082,730 - 85,098,739 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,083,270 - 85,098,282 (+)EnsemblGRCm38mm10GRCm38
MGSCv37887,607,168 - 87,622,638 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36887,973,435 - 87,987,622 (+)NCBIMGSCv36mm8
Celera889,377,736 - 89,392,568 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.55NCBI
Man2b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,743,812 - 31,770,284 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,743,813 - 31,770,560 (-)NCBIChiLan1.0ChiLan1.0
MAN2B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22017,575,076 - 17,595,722 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11916,575,673 - 16,596,297 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01912,208,319 - 12,228,934 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11912,954,103 - 12,974,056 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1912,954,103 - 12,974,056 (-)Ensemblpanpan1.1panPan2
MAN2B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,446,162 - 49,461,812 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,319,770 - 49,335,161 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02049,964,867 - 49,980,270 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,964,838 - 49,985,978 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12049,175,662 - 49,191,234 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,602,404 - 49,618,026 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,844,716 - 49,860,091 (+)NCBIUU_Cfam_GSD_1.0
Man2b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,561,069 - 208,578,396 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,774,773 - 1,793,670 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,776,212 - 1,793,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAN2B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,329,045 - 66,348,056 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1266,329,051 - 66,347,051 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,706,800 - 66,724,791 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAN2B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,334,639 - 11,355,391 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,334,752 - 11,355,334 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660748,442,103 - 8,462,838 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Man2b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624901285,978 - 307,249 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624901285,981 - 307,177 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Man2b1
54 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:98
Count of miRNA genes:88
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000037699
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat

Markers in Region
D19Rat13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21923,069,265 - 23,069,484 (-)MAPPERmRatBN7.2
Rnor_6.01926,201,726 - 26,201,944NCBIRnor6.0
Rnor_5.01937,177,349 - 37,177,567UniSTSRnor5.0
RGSC_v3.41924,725,428 - 24,725,843RGDRGSC3.4
RGSC_v3.41924,725,553 - 24,725,771UniSTSRGSC3.4
RGSC_v3.11924,730,254 - 24,730,669RGD
Celera1922,627,236 - 22,627,454UniSTS
FHH x ACI Map1921.7099RGD
FHH x ACI Map1921.7099UniSTS
Cytogenetic Map19q11UniSTS
AU047579  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21923,059,835 - 23,060,066 (-)MAPPERmRatBN7.2
Rnor_6.01926,211,292 - 26,211,524NCBIRnor6.0
Rnor_5.01937,186,915 - 37,187,147UniSTSRnor5.0
RGSC_v3.41924,716,121 - 24,716,353UniSTSRGSC3.4
Celera1922,617,804 - 22,618,036UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000037699   ⟹   ENSRNOP00000030766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1923,055,097 - 23,074,389 (-)Ensembl
Rnor_6.0 Ensembl1926,196,837 - 26,216,267 (+)Ensembl
RefSeq Acc Id: NM_199404   ⟹   NP_955436
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,959,964 - 39,979,246 (-)NCBI
mRatBN7.21923,055,092 - 23,074,372 (-)NCBI
Rnor_6.01926,196,837 - 26,216,268 (+)NCBI
Rnor_5.01937,172,434 - 37,191,891 (+)NCBI
RGSC_v3.41924,711,378 - 24,730,659 (-)RGD
Celera1922,613,060 - 22,632,343 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255273   ⟹   XP_006255335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,959,968 - 39,979,299 (-)NCBI
mRatBN7.21923,055,096 - 23,074,392 (-)NCBI
Rnor_6.01926,196,798 - 26,216,264 (+)NCBI
Rnor_5.01937,172,434 - 37,191,891 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097817   ⟹   XP_038953745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,959,968 - 39,979,299 (-)NCBI
mRatBN7.21923,055,096 - 23,074,391 (-)NCBI
RefSeq Acc Id: XM_039097818   ⟹   XP_038953746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,959,968 - 39,979,299 (-)NCBI
mRatBN7.21923,055,096 - 23,074,398 (-)NCBI
RefSeq Acc Id: XM_063278113   ⟹   XP_063134183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81939,962,444 - 39,979,299 (-)NCBI
RefSeq Acc Id: NP_955436   ⟸   NM_199404
- Peptide Label: precursor
- UniProtKB: Q6P762 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255335   ⟸   XM_006255273
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000030766   ⟸   ENSRNOT00000037699
RefSeq Acc Id: XP_038953746   ⟸   XM_039097818
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038953745   ⟸   XM_039097817
- Peptide Label: isoform X2
- UniProtKB: F7FG85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134183   ⟸   XM_063278113
- Peptide Label: isoform X4
Protein Domains
Glycoside hydrolase family 38 central

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P762-F1-model_v2 AlphaFold Q6P762 1-1009 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701043
Promoter ID:EPDNEW_R11566
Type:initiation region
Name:Man2b1_1
Description:mannosidase, alpha, class 2B, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01926,196,844 - 26,196,904EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3039 AgrOrtholog
BioCyc Gene G2FUF-6149 BioCyc
Ensembl Genes ENSRNOG00000023910 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037699.4 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.50 UniProtKB/TrEMBL
  2.60.40.1180 UniProtKB/TrEMBL
  2.60.40.1360 UniProtKB/TrEMBL
  3.20.110.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599365 IMAGE-MGC_LOAD
InterPro GH38_C UniProtKB/TrEMBL
  Glyco_hydro-type_carb-bd UniProtKB/TrEMBL
  Glyco_hydro/deAcase_b/a-brl UniProtKB/TrEMBL
  Glyco_hydro_38/57_N UniProtKB/TrEMBL
  Glyco_hydro_38_C UniProtKB/TrEMBL
  Glyco_hydro_38_cen_dom UniProtKB/TrEMBL
  Glyco_hydro_38_cen_sf UniProtKB/TrEMBL
  Glyco_hydro_38_core UniProtKB/TrEMBL
  Glyco_hydro_57/38_cen UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glycosyl_Hydrlase_38 UniProtKB/TrEMBL
  Man2a1-like_dom UniProtKB/TrEMBL
KEGG Report rno:361378 UniProtKB/TrEMBL
MGC_CLONE MGC:72561 IMAGE-MGC_LOAD
NCBI Gene Man2b1 ENTREZGENE
PANTHER ALPHA-MANNOSIDASE UniProtKB/TrEMBL
  ALPHA-MANNOSIDASE 2-RELATED UniProtKB/TrEMBL
Pfam Alpha-mann_mid UniProtKB/TrEMBL
  Glyco_hydro38C2 UniProtKB/TrEMBL
  Glyco_hydro_38 UniProtKB/TrEMBL
  Glyco_hydro_38C UniProtKB/TrEMBL
  Laman-like_dom UniProtKB/TrEMBL
PhenoGen Man2b1 PhenoGen
RatGTEx ENSRNOG00000023910 RatGTEx
SMART Alpha-mann_mid UniProtKB/TrEMBL
Superfamily-SCOP Gal_mut_like UniProtKB/TrEMBL
  Glyco_hydro/deAcase_b/a-brl UniProtKB/TrEMBL
  SSF88688 UniProtKB/TrEMBL
UniProt F7FG85 ENTREZGENE, UniProtKB/TrEMBL
  Q6P762 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-06 Man2b1  mannosidase, alpha, class 2B, member 1  Man2b1  mannosidase 2, alpha B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-28 Man2b1  mannosidase 2, alpha B1  MGC72561  similar to mannosidase 2, alpha B1  Data merged from RGD:735135 737654 APPROVED
2002-11-06 Man2b1  mannosidase 2, alpha B1  Manb  Mannosidase, alpha B, lysosomal  Symbol and Name updated 625702 APPROVED
2002-06-10 Manb  Mannosidase, alpha B, lysosomal      Symbol and Name status set to approved 70586 APPROVED