Itgam (integrin subunit alpha M) - Rat Genome Database

Name: Itgam
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Itgam (integrin subunit alpha M) Rattus norvegicus

Analyze

Symbol:

Itgam

Name:

integrin subunit alpha M

RGD ID:

2926

Description:

Predicted to enable several functions, including complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Predicted to contribute to cargo receptor activity. Predicted to be involved in several processes, including endocytosis; positive regulation of myeloid leukocyte mediated immunity; and positive regulation of neuron death. Predicted to act upstream of or within several processes, including activated T cell proliferation; microglia development; and neutrophil chemotaxis. Predicted to be located in several cellular components, including external side of plasma membrane; extracellular space; and plasma membrane raft. Predicted to be part of integrin alphaM-beta2 complex. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M); PARTICIPATES IN integrin mediated signaling pathway; Entamoebiasis pathway; Leishmaniasis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Cd11b; integrin alpha M; Integrin alpha-M; integrin, alpha M

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	182,659,047 - 182,709,495 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	182,659,000 - 182,709,503 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	191,009,691 - 191,059,554 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	198,195,778 - 198,245,649 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	190,866,175 - 190,916,092 (+)	NCBI	Rnor_WKY
Rnor_6.0	1	199,495,312 - 199,545,738 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	199,495,298 - 199,623,960 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	206,522,794 - 206,573,619 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	187,334,413 - 187,385,583 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	187,484,293 - 187,535,464 (+)	NCBI
Celera	1	180,308,890 - 180,355,319 (+)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute promyelocytic leukemia (ISO)

allergic contact dermatitis (ISO)

branched-chain keto acid dehydrogenase kinase deficiency (ISO)

genetic disease (ISO)

glomerulonephritis (ISO)

hyperglycemia (ISO)

hyperinsulinism (ISO)

ileitis (ISO)

Insulin Resistance (ISO)

Invasive Candidiasis (ISO)

lupus nephritis (ISO)

Lupus Vasculitis, Central Nervous System (ISO)

nephritis (ISO)

Nerve Degeneration (ISO)

Neuralgia (IEP)

obesity (ISO)

systemic lupus erythematosus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(S)-ropivacaine (ISO)

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,5-hexanedione (EXP,ISO)

2-acetyl-1-alkyl-sn-glycero-3-phosphocholine (ISO)

2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid (ISO)

3,3',5-triiodo-L-thyronine (ISO)

3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-mercaptopropanoic acid (ISO)

3-methyladenine (ISO)

3-phenoxybenzoic acid (ISO)

4-hydroxynon-2-enal (ISO)

5-aza-2'-deoxycytidine (ISO)

9-cis-retinoic acid (ISO)

acetamide (EXP)

acetylleucyl-leucyl-norleucinal (ISO)

acrylamide (EXP)

agathisflavone (EXP)

all-trans-4-oxoretinol (ISO)

all-trans-retinoic acid (ISO)

alternariol (ISO)

ammonium chloride (EXP)

anthra[1,9-cd]pyrazol-6(2H)-one (ISO)

Antimony trioxide (ISO)

antirheumatic drug (ISO)

apocynin (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

asperentin (ISO)

atorvastatin calcium (ISO)

auranofin (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bupivacaine (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

Calcimycin (ISO)

calciol (ISO)

calcitriol (ISO)

carbon nanotube (EXP,ISO)

carnosic acid (ISO)

chlordecone (ISO)

chloroprene (ISO)

chloroquine (ISO)

choline (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

curcumin (ISO)

cypermethrin (ISO)

DAPT (ISO)

deguelin (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibenziodolium (ISO)

dichlorvos (EXP)

diclofenac (ISO)

dimemorfan (ISO)

dimethyl sulfoxide (ISO)

dioxygen (EXP,ISO)

disulfiram (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

epalrestat (ISO)

estrone (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

ethylenediaminetetraacetic acid (ISO)

everolimus (ISO)

excitatory amino acid agonist (EXP)

fenvalerate (EXP)

flavonoids (EXP)

fluoxetine (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gefitinib (ISO)

genistein (ISO)

Ginkgoic acid (ISO)

ginsenoside Rb1 (EXP)

glutathione (ISO)

glyburide (EXP)

GW 4064 (ISO)

halothane (ISO)

heparin (ISO)

hydralazine (ISO)

hydrogen peroxide (ISO)

ibuprofen (EXP)

indometacin (ISO)

iron atom (ISO)

iron(0) (ISO)

isoflurane (ISO)

isoliquiritigenin (ISO)

isoprenaline (ISO)

kaempferol (ISO)

kainic acid (ISO)

KT 5720 (ISO)

L-methionine (ISO)

lactacystin (ISO)

lead nitrate (ISO)

leukotriene B4 (ISO)

lidocaine (EXP,ISO)

lipopolysaccharide (EXP,ISO)

lithium chloride (ISO)

lithocholic acid (ISO)

LY294002 (ISO)

maneb (ISO)

manganese atom (EXP)

manganese(0) (EXP)

manganese(II) chloride (EXP)

mechlorethamine (EXP)

memantine (EXP)

methamphetamine (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methyllycaconitine (ISO)

ML-7 (ISO)

Morphine-3-glucuronide (EXP)

mycophenolic acid (ISO)

mycotoxin (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

N-(6-acetamidohexyl)acetamide (ISO)

N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide (ISO)

N-acetyl-L-cysteine (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-formyl-L-methionyl-L-leucyl-L-phenylalanine (ISO)

N-methyl-4-phenylpyridinium (EXP,ISO)

N-tosyl-L-phenylalanyl chloromethyl ketone (ISO)

neoechinulin A (ISO)

nickel atom (ISO)

notoginsenoside R1 (EXP)

ochratoxin A (EXP)

ozone (EXP,ISO)

paclitaxel (EXP,ISO)

paracetamol (ISO)

paraquat (EXP,ISO)

paricalcitol (ISO)

parthenolide (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenethyl caffeate (ISO)

phenobarbital (EXP)

phorbol 13-acetate 12-myristate (ISO)

plaunotol (ISO)

pluronic P-123 (ISO)

Poloxamer (ISO)

poly(I:C) (EXP)

poly(styrene) (ISO)

progesterone (ISO)

pyrithiamine (EXP)

pyrithione (ISO)

quartz (EXP)

quercetin (ISO)

reparixin (ISO)

resveratrol (EXP,ISO)

rimonabant (EXP)

rolipram (ISO)

rotenone (EXP)

rutin (EXP)

ryanodine (ISO)

SB 203580 (ISO)

SB 431542 (ISO)

senecionine (ISO)

sevoflurane (EXP)

silicon dioxide (ISO)

simvastatin (EXP,ISO)

sirolimus (ISO)

sodium arsenite (ISO)

sodium fluoride (EXP)

sodium stibogluconate (ISO)

Soman (EXP)

staurosporine (ISO)

sterigmatocystin (ISO)

streptozocin (EXP)

succimer (ISO)

sulfasalazine (ISO)

sulforaphane (ISO)

sulfoxaflor (EXP)

tacrine (EXP)

tamibarotene (ISO)

tamoxifen (ISO)

Tanshinone I (ISO)

tepoxalin (ISO)

testosterone (EXP)

tetrachloromethane (ISO)

tetracycline (ISO)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (EXP)

tributylstannane (EXP,ISO)

trichostatin A (ISO)

trimethyltin (EXP,ISO)

triptonide (ISO)

tungsten (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

vitamin D (ISO)

xestospongin C (ISO)

Y-27632 (ISO)

zileuton (ISO)

zinc atom (ISO)

zinc protoporphyrin (ISO)

zinc sulfate (ISO)

zinc(0) (ISO)

ziram (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activated T cell proliferation (ISO)

amyloid-beta clearance (ISO)

apoptotic signaling pathway (ISO)

cell adhesion (ISO)

cell surface receptor signaling pathway involved in cell-cell signaling (ISO)

cell-cell adhesion (ISO)

cellular extravasation (ISO)

complement-mediated synapse pruning (ISO)

ectodermal cell differentiation (ISO)

forebrain development (ISO)

integrin-mediated signaling pathway (IEA)

leukocyte adhesion to vascular endothelial cell (ISO)

leukocyte cell-cell adhesion (ISO)

leukocyte migration involved in inflammatory response (ISO)

microglia development (ISO)

microglial cell activation (ISO)

negative regulation of dopamine metabolic process (ISO)

neutrophil apoptotic process (ISO)

neutrophil chemotaxis (ISO)

phagocytosis (ISO)

phagocytosis, engulfment (ISO)

positive regulation of hippocampal neuron apoptotic process (ISO)

positive regulation of mast cell differentiation (ISO)

positive regulation of microglial cell mediated cytotoxicity (ISO)

positive regulation of neuron death (ISO)

positive regulation of neutrophil degranulation (ISO)

positive regulation of oxidative stress-induced neuron death (ISO)

positive regulation of prostaglandin-E synthase activity (ISO)

positive regulation of protein targeting to membrane (ISO)

positive regulation of superoxide anion generation (ISO)

receptor-mediated endocytosis (ISO)

vertebrate eye-specific patterning (ISO)

Cellular Component

cell surface (ISO)

external side of plasma membrane (ISO)

extracellular space (ISO)

integrin alphaM-beta2 complex (ISO)

membrane (ISO)

nucleus (ISO)

plasma membrane (ISO)

plasma membrane raft (ISO)

Molecular Function

cargo receptor activity (ISO)

complement component C3b binding (ISO)

heat shock protein binding (ISO)

heparan sulfate proteoglycan binding (ISO)

heparin binding (ISO)

metal ion binding (IEA)

opsonin binding (ISO)

protein binding (ISO)

protein-containing complex binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

Entamoebiasis pathway (IEA)

integrin mediated signaling pathway (ISO,ISS)

Leishmaniasis pathway (IEA)

phagocytosis pathway (IEA)

Staphylococcus aureus infection pathway (IEA)

tuberculosis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Mac-1 (CD11b/CD18) links inflammation and thrombosis after glomerular injury.	Hirahashi J, etal., Circulation. 2009 Sep 29;120(13):1255-65. Epub 2009 Sep 14.
2.	Integrins: bidirectional, allosteric signaling machines.	Hynes RO Cell 2002 Sep 20;110(6):673-87.
3.	Organ-specific innate immune responses in a mouse model of invasive candidiasis.	Lionakis MS, etal., J Innate Immun. 2011;3(2):180-99. doi: 10.1159/000321157. Epub 2010 Nov 9.
4.	Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease.	Maiguel D, etal., Sci Signal. 2011 Sep 6;4(189):ra57. doi: 10.1126/scisignal.2001811.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.	Sanchez E, etal., Ann Rheum Dis. 2011 Jun 30.
13.	The integrins.	Takada Y, etal., Genome Biol. 2007;8(5):215.
14.	Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies.	Tamatani T, etal., Eur J Immunol. 1991 Mar;21(3):627-33.
15.	Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain.	Tanga FY, etal., Neurochem Int 2004 Jul-Aug;45(2-3):397-407.

Additional References at PubMed

PMID:8043862	PMID:8552190	PMID:8557754	PMID:8562500	PMID:8769481	PMID:8788039	PMID:8986723	PMID:9324354	PMID:9862668	PMID:10528208	PMID:10848813	PMID:12163569
PMID:12496435	PMID:12529407	PMID:14609575	PMID:15072240	PMID:15138196	PMID:15210787	PMID:15457581	PMID:15795238	PMID:15845452	PMID:16093349	PMID:16680014	PMID:16937496
PMID:16973387	PMID:18685038	PMID:18981141	PMID:19015308	PMID:19234460	PMID:19342649	PMID:19575970	PMID:19723499	PMID:20199584	PMID:20228271	PMID:20578039	PMID:20660734
PMID:21193407	PMID:22099750	PMID:22438044	PMID:22632727	PMID:23154389	PMID:23376485	PMID:23533145	PMID:23550035	PMID:23981064	PMID:24029230	PMID:24913911	PMID:25645918
PMID:25667449	PMID:28807980

Genomics

Comparative Map Data

Itgam
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	182,659,047 - 182,709,495 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	182,659,000 - 182,709,503 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	191,009,691 - 191,059,554 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	198,195,778 - 198,245,649 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	190,866,175 - 190,916,092 (+)	NCBI	Rnor_WKY
Rnor_6.0	1	199,495,312 - 199,545,738 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	199,495,298 - 199,623,960 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	206,522,794 - 206,573,619 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	187,334,413 - 187,385,583 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	187,484,293 - 187,535,464 (+)	NCBI
Celera	1	180,308,890 - 180,355,319 (+)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

ITGAM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	31,259,975 - 31,332,877 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	16	31,259,967 - 31,332,892 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	31,271,296 - 31,344,198 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	31,178,789 - 31,251,714 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	31,178,811 - 31,251,691	NCBI
Celera	16	28,953,869 - 29,026,766 (-)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	28,832,071 - 28,904,704 (+)	NCBI		HuRef
CHM1_1	16	32,589,199 - 32,661,884 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	31,647,380 - 31,720,298 (+)	NCBI		T2T-CHM13v2.0

Itgam
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	127,661,812 - 127,717,663 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	127,661,812 - 127,717,663 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	128,062,640 - 128,118,491 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	128,062,640 - 128,118,491 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	135,206,154 - 135,262,005 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	127,853,854 - 127,908,772 (+)	NCBI		MGSCv36	mm8
Celera	7	127,897,978 - 127,954,099 (+)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI

Itgam
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	8,116,834 - 8,260,759 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	8,116,886 - 8,160,806 (+)	NCBI	ChiLan1.0	ChiLan1.0

ITGAM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	16	31,630,983 - 31,702,406 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	31,630,146 - 31,702,406 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	16	23,634,476 - 23,707,147 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ITGAM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	16,944,062 - 16,996,525 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	16,808,971 - 16,996,286 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	18,516,000 - 18,571,559 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	17,068,771 - 17,127,224 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	17,069,907 - 17,127,159 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	16,871,848 - 16,927,654 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	16,791,010 - 16,846,822 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	17,102,490 - 17,158,038 (-)	NCBI		UU_Cfam_GSD_1.0

Itgam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	125,528,028 - 125,576,877 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	8,461,307 - 8,508,524 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936543	8,460,526 - 8,508,524 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITGAM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,957,162 - 28,042,697 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,957,324 - 28,042,691 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	1,400,356 - 1,493,976 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itgam
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	14,318,499 - 14,367,922 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	14,316,505 - 14,367,841 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Itgam
311 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	30
Count of miRNA genes:	28
Interacting mature miRNAs:	29
Transcripts:	ENSRNOT00000026748
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642722	214537671	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383635	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	154561505	199561505	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	155866514	200866514	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	156677124	201278233	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	158633083	203633083	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	213533942	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164747424	209747424	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	164747424	209747424	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	166532971	191278129	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	167909849	212909849	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169112897	197261052	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	169112897	197261052	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	173108781	218108781	Rat
631670	Iddm10	Insulin dependent diabetes mellitus QTL 10	1.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	174133260	196383635	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	174133260	219133260	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	176550523	221550523	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	176869060	221869060	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
1558658	Bw59	Body weight QTL 59	3.5	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	1	178784622	223784622	Rat
2325725	Eae31	Experimental allergic encephalomyelitis QTL 31			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	178810256	188377506	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
1302787	Stl25	Serum triglyceride level QTL 25	2.7	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	180359209	210702199	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	180359209	218108781	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	181133855	226133855	Rat
61378	Bp43	Blood pressure QTL 43	22.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	181746937	196383635	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	181759564	214537555	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	181829673	224569684	Rat
634312	Bp143	Blood pressure QTL 143	3	0.0002	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	182623426	219932796	Rat

Markers in Region

D1Smu10

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	182,657,959 - 182,658,086 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	199,494,211 - 199,494,337	NCBI	Rnor6.0
Rnor_5.0	1	206,521,673 - 206,521,799	UniSTS	Rnor5.0
RGSC_v3.4	1	187,333,197 - 187,333,323	UniSTS	RGSC3.4
Celera	1	180,307,674 - 180,307,800	UniSTS
Cytogenetic Map	1	q36	UniSTS

D1Got166

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	182,657,961 - 182,658,182 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	199,494,213 - 199,494,433	NCBI	Rnor6.0
Rnor_5.0	1	206,521,675 - 206,521,895	UniSTS	Rnor5.0
RGSC_v3.4	1	187,333,198 - 187,333,419	RGD	RGSC3.4
RGSC_v3.4	1	187,333,199 - 187,333,419	UniSTS	RGSC3.4
RGSC_v3.1	1	187,483,080 - 187,483,300	RGD
Celera	1	180,307,676 - 180,307,896	UniSTS
RH 2.0 Map	1	974.9	RGD
Cytogenetic Map	1	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			1		12						2	3
Low	3	27	48	33	7	33	8	11	62	28	28	8	8
Below cutoff		10	8	8		8			10	7	11

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC106629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC123418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF268593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U59801	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000026748 ⟹ ENSRNOP00000026748

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	182,660,679 - 182,709,503 (+)	Ensembl
Rnor_6.0 Ensembl	1	199,495,427 - 199,545,292 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000085336 ⟹ ENSRNOP00000071107

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	199,596,024 - 199,623,670 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000086003 ⟹ ENSRNOP00000073093

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	182,659,000 - 182,709,503 (+)	Ensembl
Rnor_6.0 Ensembl	1	199,495,298 - 199,623,960 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093862 ⟹ ENSRNOP00000088977

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	182,659,000 - 182,709,503 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111931 ⟹ ENSRNOP00000082821

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	182,660,679 - 182,709,503 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117515 ⟹ ENSRNOP00000077846

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	182,661,167 - 182,709,503 (+)	Ensembl

RefSeq Acc Id:

NM_012711 ⟹ NP_036843

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	182,659,176 - 182,709,051 (+)	NCBI
Rnor_6.0	1	199,495,427 - 199,545,292 (+)	NCBI
Rnor_5.0	1	206,522,794 - 206,573,619 (+)	NCBI
RGSC_v3.4	1	187,334,413 - 187,385,583 (+)	RGD
Celera	1	180,308,890 - 180,355,319 (+)	RGD

Sequence:

show sequence

ATGACTCTTAAAGTTCTTCTGGCGACAGTCCTAACCTTGTGTCATGGCTTCAATTTGGACACTG
AAAATCCCATGACCTTCCAAGAGAATGCAAGTGGCTTCGGGCAGAGTGTGATCCAGCTTGGTGA
AACCCGAGTGGTTGTTGCAGCCCCCCAGGAGGTAAAGGCGGTTAACCAGACAGGTGCCCTCTAC
CAGTGTGACTACAGCACAAACCGGTGCGACCCCATTCCCCTGCAAGTACCTCCAGAGGCTGTGA
ATATGTCCTTGGGCCTGTCCCTGGCTGCTACTACCGTCCCTCCACAGCTGCTGGCTTGTGGCCC
CACAGTACACCAGAACTGCAAGGAGAACACTTACGTCAATGGATTGTGCTACCTATTCGGCTCC
AACCTGCTGAGGAAGCCCCAGCAGTTCCCAGAGGCTCTCAGAGGATGTCCTCAGCAGGAGAGCA
ACATTGCCTTCTTGATTGACGGCTCCGGTAGCATCAACACGATCGACTTTCAGAAGATGAAGGA
ATTTGTCTCAACTGTGATGGACCAGTTCCAAAAGTCTAAAACCTTGTTCTCTTTGATGCAGTAC
TCTGATGAATTCCGGACTCACTTCACCTTCAATGATTTCAAGAGAAACCCTGACCCAAAATCAC
ATGTGAGACCCATAAGGCAGCTGAATGGAAGGACAAAAACTGCCTCAGGGATCCGTAAAGTAGT
GAGAGAACTGTTTCAGAAAATCAATGGGGCCCGGGACAATGCCGCGAAGATCCTAGTTGTCATC
ACAGACGGAGAAAAGTTTGGTGACCCCCTAAATTATGAGGATGTCATTCCTGAGGCAGAGGAAG
CAGGGATCATTCGCTACGTTATTGGGGTGGGAAACGCCTTCCACAAACCACAGTCCCGCAGAGA
GCTTGACACCATCGCGTCTAAGCCAGCTGGTGATCACGTGTTCCAAGTGGACAACTTTGAAGCT
CTGAATACCATTCGGAACCAGCTCCAGGAAAAGATCTTTGCAATTGAGGGCACCCAGACAGGAA
GTACCAGCTCCTTTGAGCATGAGATGTCTCAAGAAGGCTTTAGCGCTGCCATTACCTCCAACGG
TCCCTTGCTGGGCTCCGTGGGGAGCTTTGACTGGGCAGGTGGAGCCTTCCTGTATCCATCAAAG
GATAAAGCCAGTTTCATCAACACAACCAGAATAGATTCAGACATGAACGATGCTTACTTGGGTT
ATGCTTCTGCAGTCATCTCGAGGAACCGCGTCCAAAGCTTGGTTTTAGGGGCACCTCGATATCA
GCATATCGGCCTGGTGGTGATGTTCAAGCAGAATTTCGGTGCCTGGGAGCCCCACACTGATATC
AAGGGCAGCCAGATCGGCTCTTATTTTGGGGCCTCCCTCTGTTCTGTGGACATGGACGCTGATG
GCAATACCAACTTGATCCTCATTGGGGCCCCTCATCACTATGAGAAGACCCGAGGGGGCCAGGT
GTCAGTGTGCCCCTTGCCTAGGGGGAGAGCACGGTGGCAGTGTGAAGCTATTCTCCATGGCGAT
CAGGGCCATCCATGGGGTCGCTTTGGGGCAGCATTGACAGTGCTGGGAGATGTGAATGGAGACA
AACTGACAGATGTGGCCATTGGGGCCCCAGGAGAGCAGGAGAATCAGGGTGCTGTCTACATTTT
TCATGGAGCATCAGTAGCCAGCATCAGTACCCCTCACAGCCAGCGGATCGCAGGCGCCCGCTTC
TCCCCCGGGCTCCAGTACTTTGGGCAGTCTCTGAGTGGGGGCAAGGATCTCACAATGGACGGCC
TGATGGACTTGGCTGTGGGGGCGCAGGGGCGTCTTCTGCTGATCAGAGCCCAGCCTGTGCTGAG
ACTGGAGGCAACCATGGAATTCAGCCCCAAGAATCTAGCAAGGAGTGTGTTTGCGTGTCAAGAA
GAAGTAGTCAAAAACAAGGATGCTGGGGAGGTCAGAGTCTGCCTCCAAGTCCGCAAGAACACCA
AGGACAGGCTGCGAGAAGGAGACATCCAGAGCACTGTCACTTATGACCTGGCTTTAGACCCCGG
CCGCTCAGTTGTCCGAGCCTTCTTTGATGAAACAAAGAACGGCATACTCAGGCGCATCCGGGTC
TTTGGATTGACACAGAAATGTGAAACCCTGAAGCTAATTTTACCGGACTGTGTGGACAACTCAG
TGAGTCCCATCATCCTGCGCCTTAATTACACACTGGTTGGGGAGCCCTTGCGGTCCTCTAGGGA
CCTTCGGCCAGTTCTGGCTATGGAGGCTCAGAGGATCTTCACAGCTATGTTTCCCTTTGAGAAG
AATTGTGGCAATGACACCATTTGCCAGGATGATCTCAGCATCACCGTGAGTTCCACACGCGTGA
ACACTTTGGTGGTGGGAGACTCCCGGGACTTTGACGTGAGTGTGACTCTGAGAAATGATGGCGA
GGATTCCTATGGGACCAAGGTTACCTGCTATTACCCATCTGGCTTGTCTTACCGGAAGGTGTCA
GCAAGCCAGAACCAGTTCTCCAAGAAGCCTTGGCGTGTGATAGCTGAGCCCAGTTCTTCTGAAG
GGCAAGGGGTTCTGAAGAGCACCATCTGGGACATAAACCATCCCATCTTTCCCGCTAATTCTGA
GGTCACGTTTAATGTCACATTTGATGTGGACTCTGATGCCTCCCTTGGGAACAAACTGCTCCTC
AAGGTCGTTGTGACCAGTGAGAACAACGTGTCCAGGACCGACAAAACTGAGTCTCAGTTGGAGT
TGCCTGTGAAGTACGCCATCTACATGGTCGTCACCAGTGGTGAGAGTTCTATCAAATATCTCAA
CTTCACAGCTTCAGAGATGACCAGTAAGGTCATACAGCATCAGTACCAGTTCAACAACCTGGGC
CAGAGGAGCTTCCCTGTCAGCGTGGTCTTCTGGATCCCTGTCCAGATCAACAAGGTGACCATAT
GGGATCCTCCCCAGGTCACCTTCTCCCAGAACCTCTCAAGTGTCTGTCGCACTGAGCAGAAATC
CCCCTCTCACTCCAAGTTCCAGGATGAGCTTGAAAGGACCCCAGTGCTGAACTGCTCTGTTGCA
GTCTGCAAGAGAATCCAGTGTGACATCCCTTCCTTCAACAGTAAAGAAATATTCAACGTCACCC
TCCAGGGCAATCTGCTATTTGACTGGTACATCGAGACTTCTCATGACCACCTCCTGCTTGTGAG
CACTGCCGAGATCCTCTTTAACGACTCCGCATTTGCCCTACTTCCGGGGCAGGAGACGTTTGTG
AAGGCTCAGACAGAGACCAAAGTGGAGCCATATACAGTTCACAATCCTGTACCACTCATTGTGG
GCAGCTCCGTCGGAGGCCTGGTGCTCTTGGCTCTCATCACTGCTGGCCTATACAAGCTTGGCTT
TTTCAAACGACAGTACAAGGACATGATGAATGAAGCCGGTGGCCAAGATGGCCCACCTCAGTAA

hide sequence

RefSeq Acc Id:

XM_006230214 ⟹ XP_006230276

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	182,659,047 - 182,709,495 (+)	NCBI
Rnor_6.0	1	199,495,312 - 199,545,738 (+)	NCBI
Rnor_5.0	1	206,522,794 - 206,573,619 (+)	NCBI

Sequence:

show sequence

TTGCCTCTTACTTCTCTATTTTTACCCCTCTTGGCTTTAGTGGCTTCCTCAAAGTGTTTGTGGT
GCCAGCAACCCCGCAGTTCACACATCTCCTAGGGTTTTGTTCCTTTCAGTCATGACTCTTAAAT
TTCTTCTGGTGACAGTCCTAACCTTGTGTCATGGCTTCAATTTGGACACTGAAAATCCCATGAC
CTTCCAAGAGAATGCAAGAGGCTTCGGGCAGAGTGTGATCCAGCTTGGTGAAACCCGAGTGGTT
GTTGCAGCCCCCCAGGAGGTAAAGGCGGTTAACCAGACAGGTGCCCTCTACCAGTGTGACTACA
GCACAAACCGGTGCGACCCCATTCCCCTGCAAGTACCTCCAGAGGCTGTGAATATGTCCTTGGG
CCTGTCCCTGGCTGCTACTACCGTCCCTCCACAGCTGCTGGCTTGTGGCCCCACAGTACACCAG
AACTGCAAGGAGAACACTTACGTCAATGGATTGTGCTACCTATTCGGCTCCAACCTGCTGAGGA
AGCCCCAGCAGTTCCCAGAGGCTCTCAGAGGATGTCCTCAGCAGGAGAGCGACATTGCCTTCTT
GATTGACGGCTCCGGTAGCATCAACAGCATCGACTTTCAGAAGATGAAGGAATTTGTCTCAACT
GTGATGGACCAGTTCCAAAAGTCTAAAACCTTGTTCTCTTTGATGCAGTACTCTGATGAATTCC
GGACTCACTTCACCTTCAATGATTTCAAGAGAAACCCTGACCCAAAATCACATGTGAGACCCAT
AAGGCAGCTGAATGGAAGGACAAAAACTGCCTCAGGGATCCGTAAAGTAGTGAGAGAACTGTTT
CAGAAAATCAATGGGGCCCGGGACAATGCCGCGAAGATCCTAGTTGTCATCACAGACGGAGAAA
AGTTTGGTGACCCCCTAAATTATGAGGATGTCATTCCTGAGGCAGAGGAAGCAGGGATCATTCG
CTACGTTATTGGGGTGGGAAACGCCTTCCACAAACCACAGTCCCGCAGAGAGCTTGACACCATC
GCGTCTAAGCCAGCTGGTGATCACGTGTTCCAAGTGGACAACTTTGAAGCTCTGAATACCATTC
GGAACCAGCTCCAGGAAAAGATCTTTGCAATTGAGGGCACCCAGACAGGAAGTACCAGCTCCTT
TGAGCATGAGATGTCTCAAGAAGGCTTTAGCGCTGCCATTACCTCTAACGGTCCCTTGCTGGGC
TCCGTGGGGAGCTTTGACTGGGCAGGTGGAGCCTTCCTGTATCCATCAAAGGATAAAGCCACTT
TCATCAACACAACCAGAATAGATTCAGACATGAACGATGCTTACTTGGGTTATGCTTCTGCAGT
CATCTCGAGGAACCGCGTCCAAAGCTTGGTTTTAGGGGCACCTCGATATCAGCATATCGGCCTG
GTGGTGATGTTCAAGCAGAATTTCGGTGCCTGGGAGCCCCACACTGATATCAAGGGCAGCCAGA
TCGGCTCTTATTTTGGGGCCTCCCTCTGTTCTGTGGACATGGACGCTGATGGCAATACCAACTT
GATCCTCATTGGGGCCCCTCATCACTATGAGAAGACCCGAGGGGGCCAGGTGTCAGTGTGCCCC
TTGCCTAGGGGGCAGAGAGCACGGTGGCAGTGTGAAGCTATTCTCCATGGCGATCAGGGCCATC
CATGGGGTCGCTTTGGGGCAGCATTGACAGTGCTGGGAGATGTGAATGGAGACAAACTGACAGA
TGTGGCCATTGGGGCCCCAGGAGAGCAGGAGAATCAGGGTGCTGTCTACATTTTTCATGGAGCA
TCAGTAGCCAGCATCAGTACCCCTCACAGCCAGCGGATCGCAGGCGCCCGCTTCTCCCCCGGGC
TCCAGTACTTTGGGCAGTCTCTGAGTGGGGGCAAGGATCTCACAATGGACGGCCTGATGGACTT
GGCTGTGGGGGCGCAGGGGCGTCTTCTGCTGATCAGAGCCCAGCCTGTGCTGAGACTGGAGGCA
ACCATGGAATTCAGCCCCAAGAATCTAGCAAGGAGTGTGTTTGCGTGTCAAGAAGAAGTAGTCA
AAAACAAGGATGCTGGGGAGGTCAGAGTCTGCCTCCATGTCCGCAAGAACACCAAGGACAGGCT
GCGAGAAGGAGACATCCAGAGCACTGTCACTTATGACCTGGCTTTAGACCCCGGCCGCTCAGTT
GTCCGAGCCTTCTTTGATGAAACAAAGAACGGCATACTCAGGCGCATCCGGGTCTTTGGATTGA
CACAGAAATGTGAAACCCTGAAGCTAATTTTACCGGACTGTGTGGACAACTCAGTGAGTCCCAT
CATCCTGCGCCTTAATTACACACTGGTTGGGGAGCCCTTGCGGTCCTCTAGGGACCTTCGGCCA
GTTCTGGCTATGGAGGCTCAGAGGATCTTCACAGCTATGTTTCCCTTTGAGAAGAATTGTGGCA
ATGACACCATTTGCCAGGATGATCTCAGCATCACCGTGAGTTCCATACGCGTGAACACTTTGGT
GGTGGGAGACTCCCGGGACTTTGACGTGAGTGTGACTCTGAGAAATGATGGCGAGGATTCCTAT
GGGACCAAGGTTACCTGTTATTACCCATCTGGCTTGTCTTACCGGAAGGTGTCAGCAAGCCAGA
ACCAGTTCTCCAAGAAGCCTTGGCGTGTGATAGCTGAGCCCAGTTCTTCTGAAGGGCAAGGGGT
TCTGAAGAGCACCATCTGGGATATAAACCATCCCATCTTTCCCGCTAATTCTGAGGTCACGTTT
AATGTCACATTTGATGTGGACTCTGATGCCTCCCTTGGGAACAAACTGCTCCTCAAGGTCGTTG
TGACCAGCGAGAACAACGTGTCCAGGACCGACAAAACTGAGTCTCAGTTGGAGCTGCCTGTGAA
GTACGCCATCTACATGGTCGTCACCAGTGGTGAGAGTTCTATCAAATATCTCAACTTCACAGCT
TCAGAGATGACCAGTAAGGTCATACAGCATCAGTACCAGTTCAACAACCTGGGCCAGAGGAGCT
TCCCTGTCAGCGTGGTCTTCTGGATCCCTGTCCAGATCAACAAGGTGACCATATGGGATCCTCC
CCAGGTCACCTTCTCCCAGAACCTCTCAAGTGTCTGTCGCACTGAGCAGAAATCCCCCTCTCAC
TCCAAGTTCCAGGATGAGCTTGAAAGGACCCCAGTGCTGAACTGCTCTGTTGCAGTCTGCAAGA
GAATCCAGTGTGACATCCCTTCCTTCAACAGTAAAGAAATATTCAACGTCACCCTCCAGGGCAA
TCTGCTATTTGACTGGTACATCGAGACTTCTCACGACCACCTCCTGCTTGTGAGCACTGCCGAG
ATCCTCTTTAACGACTCCGCATTTGCCCTACTTCCGGGGCAGGAGACGTTTGTGAAGGCTCAGA
CAGAGACCAAAGTGGAGCCATATAAAGTTCACAACCCTGTACCACTCATTGTGGGCAGCTCCGT
CGGAGGCCTGGTGCTCTTGGCTCTCATCACTGCTGGCCTGTACAAGCTTGGCTTTTTCAAACGA
CAGTACAAGGACATGATGAATGAAGCCGCTCCCCAAGATGGCCCCCCTCAGTAATGGCCTTTGT
TCCATGGAGTGACCTCTCCAACAACAAGCAGGTCTAGACGGTCAGACCAACAGCGAGGCTGGTG
GACAGACATGTCCTTTAGAAGACTGTTGCCGTGACGTCTTATACAGAAATGGAGTTTCTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTTGGAAGTCAGAACAGCAAAGAACAGCACGCGCGCGCA
CACACACACACACACACACACACACACACGGTTTTAAACAAGTGGTAGCACTTTTTTACTGTTA
TGCATATTGTCTTTTTATTAATATGCTCAAATAATTTTATATAAGTTATAAAGTAGCTCAGAGT
ATTCCCTTGTGATTTAACATATTTAACATTTAATGTAATCTCCTTTGGACATATTATTTCCAGC
CATTTGCTATTGTGAACAATGCTGAATTAATAAATTGGGTATATCTAATTTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_036843	(Get FASTA)	NCBI Sequence Viewer
	XP_006230276	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB03226	(Get FASTA)	NCBI Sequence Viewer
	AAF81280	(Get FASTA)	NCBI Sequence Viewer
	EDM17198	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_036843 ⟸ NM_012711
- Peptide Label:	precursor
- UniProtKB:	A0A0G2K4L8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLKVLLATVLTLCHGFNLDTENPMTFQENASGFGQSVIQLGETRVVVAAPQEVKAVNQTGALY QCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGS NLLRKPQQFPEALRGCPQQESNIAFLIDGSGSINTIDFQKMKEFVSTVMDQFQKSKTLFSLMQY SDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVI TDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEA LNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSK DKASFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDI KGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGRARWQCEAILHGD QGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARF SPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQE EVVKNKDAGEVRVCLQVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRV FGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEK NCGNDTICQDDLSITVSSTRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVS ASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLL KVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLG QRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSVA VCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFV KAQTETKVEPYTVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAGGQDGPPQ hide sequence

RefSeq Acc Id:

XP_006230276 ⟸ XM_006230214

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTLKFLLVTVLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALY
QCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGS
NLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQY
SDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVI
TDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEA
LNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSK
DKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDI
KGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGQRARWQCEAILHG
DQGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGAR
FSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQ
EEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIR
VFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFE
KNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKV
SASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLL
LKVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNL
GQRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSV
AVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETF
VKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ

hide sequence

RefSeq Acc Id:

ENSRNOP00000026748 ⟸ ENSRNOT00000026748

RefSeq Acc Id:

ENSRNOP00000071107 ⟸ ENSRNOT00000085336

RefSeq Acc Id:

ENSRNOP00000073093 ⟸ ENSRNOT00000086003

RefSeq Acc Id:

ENSRNOP00000077846 ⟸ ENSRNOT00000117515

RefSeq Acc Id:

ENSRNOP00000082821 ⟸ ENSRNOT00000111931

RefSeq Acc Id:

ENSRNOP00000088977 ⟸ ENSRNOT00000093862

Protein Domains

VWFA

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690468

Promoter ID:

EPDNEW_R976

Type:

initiation region

Name:

Itgad_1

Description:

integrin subunit alpha D

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	199,495,350 - 199,495,410	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2926	AgrOrtholog
BioCyc Gene	G2FUF-57313	BioCyc
Ensembl Genes	ENSRNOG00000019728	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000026748	ENTREZGENE
	ENSRNOP00000026748.4	UniProtKB/TrEMBL
	ENSRNOP00000073093	ENTREZGENE
	ENSRNOP00000073093.2	UniProtKB/TrEMBL
	ENSRNOP00000077846.1	UniProtKB/TrEMBL
	ENSRNOP00000082821.1	UniProtKB/TrEMBL
	ENSRNOP00000088977.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026748	ENTREZGENE
	ENSRNOT00000026748.5	UniProtKB/TrEMBL
	ENSRNOT00000086003	ENTREZGENE
	ENSRNOT00000086003.2	UniProtKB/TrEMBL
	ENSRNOT00000093862.1	UniProtKB/TrEMBL
	ENSRNOT00000111931.1	UniProtKB/TrEMBL
	ENSRNOT00000117515.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.130	UniProtKB/TrEMBL
	3.40.50.410	UniProtKB/TrEMBL
	Bicelle-embedded integrin alpha(iib) transmembrane segment	UniProtKB/TrEMBL
	Integrin domains. Chain A, domain 2	UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 3	UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 4	UniProtKB/TrEMBL
InterPro	FG-GAP	UniProtKB/TrEMBL
	Int_alpha_beta-p	UniProtKB/TrEMBL
	Integrin_alpha	UniProtKB/TrEMBL
	Integrin_alpha-2	UniProtKB/TrEMBL
	Integrin_alpha_C_CS	UniProtKB/TrEMBL
	Integrin_alpha_N	UniProtKB/TrEMBL
	Integrin_dom	UniProtKB/TrEMBL
	VWF_A	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:25021	UniProtKB/TrEMBL
NCBI Gene	25021	ENTREZGENE
PANTHER	INTEGRIN ALPHA	UniProtKB/TrEMBL
	INTEGRIN ALPHA-M	UniProtKB/TrEMBL
Pfam	FG-GAP	UniProtKB/TrEMBL
	Integrin_alpha	UniProtKB/TrEMBL
	Integrin_alpha2	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
PhenoGen	Itgam	PhenoGen
PRINTS	INTEGRINA	UniProtKB/TrEMBL
	VWFADOMAIN	UniProtKB/TrEMBL
PROSITE	FG_GAP	UniProtKB/TrEMBL
	INTEGRIN_ALPHA	UniProtKB/TrEMBL
	VWFA	UniProtKB/TrEMBL
SMART	Int_alpha	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53300	UniProtKB/TrEMBL
	SSF69179	UniProtKB/TrEMBL
	SSF69318	UniProtKB/TrEMBL
UniProt	A0A0G2K4L8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5Y8A4_RAT	UniProtKB/TrEMBL
	A0A8I5ZVY4_RAT	UniProtKB/TrEMBL
	A0A8I6A686_RAT	UniProtKB/TrEMBL
	G3V8L7_RAT	UniProtKB/TrEMBL
	Q9JI30_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-11	Itgam	integrin subunit alpha M	Itgam	integrin, alpha M	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-12-15	Itgam	integrin, alpha M	Itgam	integrin alpha M	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Itgam	Integrin alpha-M			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)