Il10 (interleukin 10) - Rat Genome Database

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Gene: Il10 (interleukin 10) Rattus norvegicus
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Symbol: Il10
Name: interleukin 10
RGD ID: 2886
Description: Enables interleukin-10 receptor binding activity. Involved in several processes, including cellular response to estradiol stimulus; liver regeneration; and negative regulation of cellular biosynthetic process. Located in extracellular space. Used to study several diseases, including lung disease (multiple); perinatal necrotizing enterocolitis; sciatic neuropathy; toxic encephalopathy; and transient cerebral ischemia. Biomarker of several diseases, including alcohol use disorder; artery disease (multiple); decubitus ulcer; liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Orthologous to human IL10 (interleukin 10); PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-4 signaling pathway; allograft rejection pathway; INTERACTS WITH (+)-pilocarpine; (-)-epigallocatechin 3-gallate; (2E,4E)-hexa-2,4-dienoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CSIF; cytokine synthesis inhibitory factor; If2a; IL-10; IL10X; interferon 2a; interleukin-10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,024,921 - 45,029,586 (+)NCBIGRCr8
mRatBN7.21342,472,625 - 42,477,308 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,472,839 - 42,477,313 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1345,079,495 - 45,083,368 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,367,625 - 46,371,502 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,631,889 - 43,635,783 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,738,933 - 47,743,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,739,526 - 47,743,392 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,824,594 - 52,828,560 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,953,900 - 43,957,766 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11343,967,906 - 43,972,374 (+)NCBI
Celera1342,821,569 - 42,825,416 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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