Gstp1 (glutathione S-transferase pi 1) - Rat Genome Database

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Gene: Gstp1 (glutathione S-transferase pi 1) Rattus norvegicus
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Symbol: Gstp1
Name: glutathione S-transferase pi 1
RGD ID: 2758
Description: Enables organic cyclic compound binding activity; protein kinase binding activity; and toxic substance binding activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to epidermal growth factor stimulus; and negative regulation of smooth muscle cell chemotaxis. Predicted to be located in mitochondrion. Predicted to be part of TRAF2-GSTP1 complex. Predicted to be active in cytosol. Biomarker of cholestasis; pre-malignant neoplasm; prostate carcinoma in situ; prostatic hypertrophy; and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); carcinoma (multiple); hematologic cancer (multiple); reproductive organ cancer (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (glutathione S-transferase pi 1); PARTICIPATES IN glutathione conjugation pathway; paracetamol pharmacokinetics pathway; glutathione metabolic pathway; INTERACTS WITH (3,4-dihydroxyphenyl)acetic acid; (E)-4-hydroxynon-2-enal; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chain 7; glutathione S-transferase P; glutathione S-transferase pi 2; glutathione S-transferase, pi 2; Glutathione-S-transferase placental enzyme pi type; glutathione-S-transferase, pi 1; Glutathione-S-transferase, placental enzyme pi type; GST 7-7; GST class-pi; GST-P; Gst3; Gstp; Gstp2; MGC72668; MGC72669
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Candidate Gene For: Hcar4
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,767,237 - 210,770,242 (-)NCBIGRCr8
mRatBN7.21201,337,762 - 201,340,230 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,321,672 - 201,340,226 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1209,690,040 - 209,692,503 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,783,226 - 216,785,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01209,474,253 - 209,476,723 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,291,679 - 219,294,147 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,291,679 - 219,294,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,162,330 - 226,164,798 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,627,398 - 206,629,866 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11206,780,853 - 206,783,288 (-)NCBI
Celera1198,882,807 - 198,885,275 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
acute kidney failure  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
Aicardi-Goutieres Syndrome 3  (ISO)
Airway Obstruction  (ISO)
allergic disease  (ISO)
Alzheimer's disease  (ISO)
amphetamine abuse  (ISO)
amyotrophic lateral sclerosis  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
bone marrow disease  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
bronchopulmonary dysplasia  (ISO)
bronchus carcinoma  (ISO)
carcinoma  (ISO)
carotid artery disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemotherapy-Induced Febrile Neutropenia  (ISO)
cholangiocarcinoma  (ISO)
Cholangiofibrosis  (IEP)
cholestasis  (IEP)
Chromosome Aberrations  (ISO)
Chronic Cerebral Hypoperfusion  (IDA)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
clear cell renal cell carcinoma  (ISO)
colorectal adenoma  (ISO)
Colorectal Neoplasms  (ISO)
congenital heart disease  (ISO)
conjunctivochalasis  (ISO)
contact dermatitis  (ISO)
Cough  (ISO)
cystic fibrosis  (ISO)
diffuse large B-cell lymphoma  (ISO)
Disease Progression  (ISO)
drug allergy  (ISO)
Drug-Induced Leukopenia  (ISO)
Drug-induced Neutropenia  (ISO)
esophagus squamous cell carcinoma  (ISO)
essential tremor  (ISO)
Experimental Liver Neoplasms  (IEP,ISO)
Experimental Seizures  (IEP)
Focal Nodular Hyperplasia  (IEP)
Gallbladder Neoplasms  (ISO)
Graves' disease  (ISO)
hematopoietic system disease  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Hodgkin's lymphoma  (ISO)
hypertension  (ISO)
intellectual disability  (ISO)
Kidney Calculi  (ISO)
kidney disease  (ISO)
Kuhnt-Junius degeneration  (ISO)
Laryngeal Neoplasms  (ISO)
late onset Parkinson's disease  (ISO)
liver disease  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lymphoid leukemia  (ISO)
malignant astrocytoma  (ISO)
melanoma  (ISO)
meningitis  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
mitochondrial metabolism disease  (ISO)
movement disease  (ISO)
multiple myeloma  (ISO)
multiple sclerosis  (ISO)
myelodysplastic syndrome  (ISO)
myeloid leukemia  (ISO)
Myocardial Ischemia  (ISO)
Necrosis  (ISO)
oral squamous cell carcinoma  (ISO)
osteoporosis  (ISO)
osteosarcoma  (ISO)
ovarian cancer  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
Parkinson's disease  (ISO)
Perennial Allergic Rhinitis  (ISO)
peripheral nervous system disease  (ISO)
peritonitis  (ISO)
Plasmodium falciparum malaria  (ISO)
pre-eclampsia  (ISO)
pre-malignant neoplasm  (IEP,ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (IEP,ISO)
prostatic hypertrophy  (IEP)
Prostatic Neoplasms  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Respiratory Sounds  (ISO)
respiratory system disease  (ISO)
sarcoma  (ISO)
senile cataract  (ISO)
squamous cell carcinoma  (ISO)
Stomach Neoplasms  (ISO)
substance-induced psychosis  (ISO)
testicular cancer  (ISO)
toxic encephalopathy  (ISO)
type 2 diabetes mellitus  (ISO)
Ureteral Calculi  (ISO)
urinary bladder cancer  (IEP,ISO)
vestibular disease  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(3,4-dihydroxyphenyl)acetic acid  (EXP)
(E)-4-hydroxynon-2-enal  (EXP)
(R)-lipoic acid  (EXP)
(RS)-goitrin  (EXP)
1,2-Dibromo-3-chloropropane  (ISO)
1,2-dichlorobenzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dichloropropan-2-ol  (EXP)
1,3-dinitrobenzene  (EXP)
1,4-dioxane  (ISO)
1,4-phenylenediamine  (ISO)
1-\{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl\}-1H-imidazole  (ISO)
1-bromopropane  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-Hydroxypyrene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2,2-tetramine  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,5-di-tert-butylbenzene-1,4-diol  (EXP)
2,5-hexanedione  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP,ISO)
2-acetamidofluorene  (EXP)
2-Acetoxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine  (ISO)
2-allylphenol  (EXP,ISO)
2-amino-4,6-dinitrotoluene  (EXP)
2-amino-7-methyl-1,7-dihydro-6H-purin-6-one  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-hexenal  (ISO)
2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester  (ISO)
2-methoxyethanol  (EXP)
2-nitrofluorene  (EXP)
2-phenylpropanal  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (EXP)
3-nitropropanoic acid  (EXP)
3-phenoxybenzoic acid  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4'-hydroxydiclofenac  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-Chloronitrobenzene  (EXP)
4-hydroxynon-2-enal  (EXP,ISO)
4-Propylphenol  (EXP,ISO)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-hydroxydiclofenac  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
7,12-dimethyltetraphene  (EXP)
acetamide  (EXP)
acetic acid  (ISO)
aclacinomycin A  (ISO)
acridine orange  (ISO)
acridine orange free base  (ISO)
acrolein  (EXP,ISO)
acrylamide  (EXP)
actinomycin D  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin B1 exo-8,9-epoxide  (EXP)
aldehydo-D-glucose  (EXP)
aldosterone  (EXP)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
alpha-hexachlorocyclohexane  (EXP)
alpha-methyl-L-dopa  (ISO)
alpha-naphthoflavone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (EXP)
amphotericin B  (EXP,ISO)
angelica lactone  (ISO)
anthracene-1,8,9-triol  (ISO)
aristolochic acid A  (EXP,ISO)
arotinoid acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
asbestos  (ISO)
atovaquone  (ISO)
ATP  (ISO)
atrazine  (EXP,ISO)
Aurothioglucose  (ISO)
avobenzone  (ISO)
Bardoxolone methyl  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[c]phenanthrene  (ISO)
BENZO[G]CHRYSENE  (ISO)
Benzo[k]fluoranthene  (ISO)
benzopyran  (EXP)
benzyl isothiocyanate  (EXP,ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
betamethasone dipropionate  (ISO)
bifenthrin  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bromindione  (ISO)
Bucillamine  (ISO)
bufalin  (ISO)
buspirone  (EXP)
busulfan  (ISO)
buta-1,3-diene  (ISO)
butylated hydroxyanisole  (EXP,ISO)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cafestol  (EXP)
camptothecin  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
captafol  (ISO)
captan  (ISO)
carbamazepine-10,11-epoxide  (ISO)
carbon nanotube  (ISO)
carboplatin  (ISO)
carmustine  (ISO)
carnosic acid  (EXP,ISO)
cefaloridine  (EXP)
celecoxib  (ISO)
cerium trichloride  (ISO)
CHIR 99021  (ISO)
chlorambucil  (ISO)
chloramphenicol palmitate  (ISO)
chlorobenzene  (ISO)
chloroethene  (ISO)
chloropicrin  (ISO)
chlorotrianisene  (ISO)
chlortetracycline  (ISO)
chromium(6+)  (ISO)
cimetidine  (ISO)
cis-caffeic acid  (EXP)
cisplatin  (EXP,ISO)
Clasto-Lactacystin beta-lactone  (ISO)
clobetasol  (ISO)
clofazimine  (ISO)
clofibrate  (EXP,ISO)
clomipramine  (ISO)
clotrimazole  (ISO)
clozapine  (ISO)
cobamamide  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cortisol  (ISO)
coumarin  (EXP,ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (EXP,ISO)
crystal violet  (ISO)
cumene  (ISO)
cumene hydroperoxide  (ISO)
curcumin  (EXP,ISO)
cyclohexanols  (EXP)
cyclophosphamide  (EXP,ISO)
cycloprothrin  (ISO)
cypermethrin  (EXP)
D-glucose  (EXP)
dapsone  (ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (EXP,ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibenzofurans  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dienestrol  (ISO)
diethyl maleate  (EXP)
diethyldithiocarbamic acid  (EXP)
diethylstilbestrol  (ISO)
dihydrolipoic acid  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (EXP,ISO)
dinophysistoxin 1  (ISO)
dioxygen  (EXP)
diquat  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dopamine  (ISO)
dorsomorphin  (ISO)
doxepin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
ebselen  (EXP)
econazole  (ISO)
elemental selenium  (EXP,ISO)
emodin  (ISO)
endosulfan  (EXP)
enoxacin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP,ISO)
equilin  (ISO)
ergotamine  (ISO)
eriodictyol  (ISO)
erythrosin B  (ISO)
Estradiol 17beta-cyclopentylpropionate  (ISO)
etacrynic acid  (EXP,ISO)
ethanol  (EXP,ISO)
ethoxyquin  (EXP)
ethylbenzene  (ISO)
etoposide  (ISO)
eugenol  (EXP,ISO)
fenbendazole  (ISO)
fenofibrate  (ISO)
fenvalerate  (EXP)
ferric oxide  (EXP)
fipronil  (EXP)
flavonoids  (ISO)
flufenamic acid  (ISO)
flunarizine  (ISO)
Fluocinonide  (ISO)
flurotyl  (ISO)
flutamide  (EXP,ISO)
flutriafol  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
FR900359  (ISO)
fumaraldehyde  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
galangin  (ISO)
gamma-glutamyl-glutathione  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (EXP)
glucose  (EXP)
glutathione  (EXP,ISO)
glycerol  (ISO)
haloperidol  (ISO)
hemin  (ISO)
heptan-2-one  (ISO)
herbicide  (ISO)
hexachlorobenzene  (EXP)
hexachlorophene  (ISO)
homocysteine  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxyzine  (ISO)
hypericin  (EXP,ISO)
ifosfamide  (ISO)
imipramine  (ISO)
indirubin  (ISO)
indole-3-methanol  (EXP,ISO)
iodide salt  (EXP)
iodoquinol  (ISO)
iron dichloride  (ISO)
isomethyleugenol  (EXP,ISO)
isoniazide  (EXP)
isopimpinellin  (ISO)
isothiocyanate  (ISO)
isotretinoin  (ISO)
itraconazole  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
kahweol  (EXP)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
L-cysteine  (ISO)
L-selenocysteine  (EXP)
lansoprazole  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
leflunomide  (EXP,ISO)
lipoic acid  (EXP)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
LY294002  (EXP,ISO)
lycopene  (EXP)
malathion  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
mebendazole  (ISO)
Meclizine  (ISO)
mefenamic acid  (ISO)
MeIQx  (ISO)
melatonin  (EXP,ISO)
melphalan  (ISO)
merbromin  (ISO)
mercury atom  (EXP,ISO)
mercury dibromide  (ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP,ISO)
Mesna  (ISO)
metformin  (EXP)
methamphetamine  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate  (ISO)
methylarsonic acid  (EXP)
methylene blue  (ISO)
methylmercury chloride  (ISO)
microcystin  (EXP)
microcystin RR  (ISO)
microcystin-LR  (ISO)
minocycline  (EXP)
mitomycin C  (ISO)
Mitotane  (ISO)
MK 571  (ISO)
monobromobimane  (ISO)
monocrotophos  (EXP,ISO)
monosodium L-glutamate  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-1,4-benzoquinone imine  (EXP,ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-hydroxy-PhIP  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosomorpholine  (EXP)
naphthalene  (ISO)
naringin  (EXP)
nefazodone  (EXP)
nevirapine  (ISO)
nicotinamide  (EXP)
nifedipine  (ISO)
nimesulide  (EXP)
nisoldipine  (ISO)
nitrendipine  (ISO)
nitrogen dioxide  (ISO)
Nutlin-3  (ISO)
O-acetyl-L-carnitine  (EXP)
O-methyleugenol  (EXP,ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
oltipraz  (EXP,ISO)
omeprazole  (EXP)
orphenadrine  (EXP)
oxaliplatin  (ISO)
oxiconazole  (ISO)
oxidopamine  (EXP,ISO)
oxybenzone  (EXP)
oxyphenbutazone  (ISO)
ozone  (ISO)
p-toluidine  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pararosaniline free base  (ISO)
parathion  (ISO)
pentachlorobenzene  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenethyl caffeate  (EXP)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenolphthalein  (ISO)
Phenoxybenzamine  (ISO)
phenylbutazone  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP,ISO)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramide mustard  (EXP)
phylloquinone  (ISO)
pioglitazone  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
platinum  (ISO)
platinum(0)  (ISO)
plumbagin  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
PRIM-O-GLUCOSYLCIMIFUGIN  (ISO)
propane-1,2-diol  (ISO)
Propiverine  (EXP)
Pyrantel pamoate  (ISO)
pyrazinecarboxamide  (EXP)
Pyridostigmine bromide  (EXP)
pyrimethamine  (ISO)
pyrimidifen  (ISO)
quercetin  (EXP,ISO)
quercitrin  (ISO)
quinidine  (ISO)
quinine  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-hexylglutathione  (ISO)
salvianolic acid B  (ISO)
sanguinarine  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
selenium atom  (EXP,ISO)
selenomethionine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
soybean oil  (EXP)
stavudine  (EXP)
stilbene oxide  (EXP)
streptozocin  (EXP)
styrene  (ISO)
styrene oxide  (ISO)
Sudan I  (EXP)
sulconazole  (ISO)
sulfamethoxazole  (ISO)
sulfaphenazole  (ISO)
sulfasalazine  (EXP)
sulfinpyrazone  (ISO)
sulforaphane  (EXP,ISO)
sulfotep  (ISO)
sulfur dioxide  (ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
Tanshinone I  (ISO)
tauroursodeoxycholic acid  (EXP)
temephos  (ISO)
temozolomide  (ISO)
teniposide  (ISO)
terbinafine  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
Testosterone propionate  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
thiophenes  (ISO)
thiostrepton  (ISO)
Thiotepa  (ISO)
Thonningianin A  (ISO)
thymoquinone  (EXP)
Tiopronin  (ISO)
titanium dioxide  (ISO)
tolnaftate  (ISO)
toluene  (EXP,ISO)
toluene 2,4-diisocyanate  (ISO)
tranilast  (ISO)
trans-caffeic acid  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimethylarsine oxide  (EXP)
triphenyl phosphate  (EXP)
Tris(1-aziridinyl)phosphine oxide  (ISO)
Tris(2,3-dibromopropyl) phosphate  (ISO)
troglitazone  (EXP,ISO)
uranium atom  (EXP)
valproic acid  (ISO)
vincaleukoblastine  (EXP)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin D  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
WR-1065  (ISO)
xanthohumol  (ISO)
XAV939  (ISO)
zearalenone  (ISO)
zerumbone  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (IEP)
cellular oxidant detoxification  (IEA)
cellular response to cell-matrix adhesion  (IEP)
cellular response to epidermal growth factor stimulus  (IEP)
cellular response to glucocorticoid stimulus  (IEP)
cellular response to insulin stimulus  (IEP)
cellular response to lipopolysaccharide  (ISO,ISS)
common myeloid progenitor cell proliferation  (ISO,ISS)
glutathione derivative biosynthetic process  (ISO,ISS)
glutathione metabolic process  (ISO)
hepoxilin biosynthetic process  (ISO,ISS)
linoleic acid metabolic process  (ISO)
negative regulation of biosynthetic process  (ISO)
negative regulation of canonical NF-kappaB signal transduction  (ISO,ISS)
negative regulation of ERK1 and ERK2 cascade  (ISO,ISS)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of fibroblast proliferation  (ISO,ISS)
negative regulation of interleukin-1 beta production  (ISO,ISS)
negative regulation of JUN kinase activity  (ISO)
negative regulation of leukocyte proliferation  (ISO,ISS)
negative regulation of MAP kinase activity  (ISO)
negative regulation of monocyte chemotactic protein-1 production  (ISO,ISS)
negative regulation of nitric-oxide synthase biosynthetic process  (ISO,ISS)
negative regulation of protein kinase activity  (IMP,ISO)
negative regulation of smooth muscle cell chemotaxis  (IMP)
negative regulation of stress-activated MAPK cascade  (ISO,ISS)
negative regulation of tumor necrosis factor production  (ISO,ISS)
negative regulation of vascular associated smooth muscle cell proliferation  (IMP)
oligodendrocyte development  (IEP)
positive regulation of superoxide anion generation  (ISO,ISS)
prostaglandin metabolic process  (ISO,ISS)
regulation of ERK1 and ERK2 cascade  (ISO,ISS)
regulation of stress-activated MAPK cascade  (ISO,ISS)
response to amino acid  (IEP)
response to estradiol  (IEP)
response to ethanol  (IEP)
response to L-ascorbic acid  (IEP)
response to nutrient levels  (IEP)
response to reactive oxygen species  (ISO,ISS)
response to toxic substance  (IEP)
xenobiotic metabolic process  (ISO,TAS)

Cellular Component

References

References - curated
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71. Electronic Transfer of LocusLink and RefSeq Data