Ets1 (ETS proto-oncogene 1, transcription factor) - Rat Genome Database

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Gene: Ets1 (ETS proto-oncogene 1, transcription factor) Rattus norvegicus
Analyze
Symbol: Ets1
Name: ETS proto-oncogene 1, transcription factor
RGD ID: 2583
Description: Enables histone acetyltransferase binding activity and sequence-specific DNA binding activity. Involved in several processes, including angiogenesis involved in wound healing; diencephalon development; and estrous cycle. Located in nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); Ets-1; Etsoncb; MGC124638; p54; protein C-ets-1; Tpl1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ets1em1Mcwi  
Genetic Models: SS-Ets1em1Mcwi-/+ SS-Ets1em1Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2831,045,909 - 31,168,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl831,045,945 - 31,168,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx835,176,570 - 35,239,049 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0833,471,056 - 33,533,529 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0831,333,929 - 31,396,429 (+)NCBIRnor_WKY
Rnor_6.0833,756,634 - 33,879,625 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,816,386 - 33,879,625 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,798,598 - 33,921,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,481,694 - 32,545,237 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1832,490,458 - 32,553,970 (+)NCBI
Celera832,555,513 - 32,617,691 (+)NCBICelera
RH 3.4 Map8268.3RGD
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antimycin A  (ISO)
aripiprazole  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
benzophenanthridine  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
crocidolite asbestos  (ISO)
cumene  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP,ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
etoposide  (ISO)
fenamidone  (ISO)
flavonoids  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
GW 7647  (EXP)
hydrogen peroxide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
leflunomide  (ISO)
mercury dibromide  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
mibolerone  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (EXP,ISO)
nickel sulfate  (EXP)
ouabain  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PD 0325901  (ISO)
phenethyl caffeate  (EXP)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
Rebamipide  (EXP)
resveratrol  (ISO)
rotenone  (EXP)
SB 203580  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
spironolactone  (EXP)
streptozocin  (ISO)
sulindac  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
Tributyltin oxide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis involved in wound healing  (IEP)
cell differentiation  (IBA)
cell motility  (ISO)
cellular response to hydrogen peroxide  (IEP)
DNA-templated transcription  (ISO)
DNA-templated transcription elongation  (ISO)
estrous cycle  (IEP)
female pregnancy  (IEP)
hypothalamus development  (IEP)
immune system process  (IEA)
negative regulation of cell cycle  (ISO)
negative regulation of inflammatory response  (ISO)
obsolete positive regulation of cellular component movement  (ISO)
pituitary gland development  (IEP)
PML body organization  (ISO)
positive regulation of angiogenesis  (IMP,ISO)
positive regulation of blood vessel endothelial cell migration  (ISO)
positive regulation of cell migration  (IMP)
positive regulation of cell population proliferation  (IMP)
positive regulation of DNA-templated transcription  (ISO,ISS)
positive regulation of endothelial cell migration  (ISO,ISS)
positive regulation of erythrocyte differentiation  (ISO,ISS)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of leukocyte adhesion to vascular endothelial cell  (ISO)
positive regulation of miRNA transcription  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
regulation of angiogenesis  (ISO,ISS)
regulation of apoptotic process  (ISO)
regulation of DNA-templated transcription  (ISO)
regulation of extracellular matrix disassembly  (IMP)
regulation of transcription by RNA polymerase II  (IBA,IEA,ISO)
response to antibiotic  (ISO)
response to estradiol  (IEP)
response to hypoxia  (IEP)
response to interleukin-1  (IEP)
response to laminar fluid shear stress  (IEP)
response to mechanical stimulus  (IEP)
response to salt  (IEP)
response to wounding  (IEP)
transcription by RNA polymerase II  (ISO)

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (ISO)
nucleus  (IBA,IDA,IEA,ISO,ISS)
transcription regulator complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Cellular basis of diabetic nephropathy: V. Endoglin expression levels and diabetic nephropathy risk in patients with Type 1 diabetes. Alvarez-Munoz P, etal., J Diabetes Complications. 2009 Apr 21.
2. HLA and non-HLA genetic factors in Japanese IDDM. Aparicio JM Hokkaido Igaku Zasshi. 1991 Nov;66(6):780-93.
3. Non-HLA genetic factors and insulin dependent diabetes mellitus in the Japanese: TCRA, TCRB and TCRG, INS, THY1, CD3D and ETS1. Aparicio JM, etal., Dis Markers. 1990 Sep-Oct;8(5):283-94.
4. Effects of provirus integration in the Tpl-1/Ets-1 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas: levels of expression, polyadenylation, transcriptional initiation, and differential splicing of the Ets-1 mRNA. Bellacosa A, etal., J Virol 1994 Apr;68(4):2320-30.
5. Peroxide-inducible Ets-1 mediates platelet-derived growth factor receptor-alpha gene transcription in vascular smooth muscle cells. Bonello MR, etal., Am J Pathol. 2005 Oct;167(4):1149-59.
6. Coordinated expression of Ets-1, pERK1/2, and VEGF in retina of streptozotocin-induced diabetic rats. Du ZJ, etal., Ophthalmic Res. 2007;39(4):224-31. Epub 2007 Jun 29.
7. Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase-9 expression in rat mesangial cells: involvement of nuclear factor-kappaB and Ets transcription factors. Eberhardt W, etal., Mol Endocrinol. 2002 Aug;16(8):1752-66.
8. Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat. Feng W, etal., Kidney Int. 2020 Mar;97(3):528-537. doi: 10.1016/j.kint.2019.09.025. Epub 2019 Oct 22.
9. Mutant p53: one name, many proteins. Freed-Pastor WA and Prives C, Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112.
10. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
12. The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cells. Hua P, etal., Am J Physiol Renal Physiol. 2012 Jun 1;302(11):F1418-29. doi: 10.1152/ajprenal.00477.2011. Epub 2012 Feb 22.
13. Regulated expression of the ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro. Hultgardh-Nilsson A, etal., Circ Res. 1996 Apr;78(4):589-95.
14. Expression of Ets-1 transcription factor in relation to angiogenesis in the healing process of gastric ulcer. Ito M, etal., Biochem Biophys Res Commun. 1998 May 8;246(1):123-7.
15. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
16. Expression of the c-ets1 gene in the hypothalamus and pituitary during rat development. Laurent-Huck FM, etal., Brain Res Dev Brain Res. 1996 Nov 22;97(1):107-17.
17. Estrogen-induced Ets-1 promotes capillary formation in an in vitro tumor angiogenesis model. Lincoln DW 2nd, etal., Breast Cancer Res Treat. 2003 Mar;78(2):167-78.
18. Shear stress-induced Ets-1 modulates protease inhibitor expression in microvascular endothelial cells. Milkiewicz M, etal., J Cell Physiol. 2008 Nov;217(2):502-10.
19. Transcription factor Ets-1 is essential for mesangial matrix remodeling. Mizui M, etal., Kidney Int. 2006 Jul;70(2):298-305. Epub 2006 May 31.
20. Expression of matrix metalloproteinase-9 associated with ets-1 proto-oncogene in rat tubulointerstitial cells. Naito T, etal., Nephrol Dial Transplant. 2005 Nov;20(11):2333-48. Epub 2005 Jul 26.
21. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
22. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
23. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
24. Mechanical strain induces osteogenic differentiation: Cbfa1 and Ets-1 expression in stretched rat mesenchymal stem cells. Qi MC, etal., Int J Oral Maxillofac Surg. 2008 May;37(5):453-8. Epub 2008 Feb 12.
25. GOA pipeline RGD automated data pipeline
26. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
27. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
28. Inactivation of Ets 1 transcription factor by a specific decoy strategy reduces rat C6 glioma cell proliferation and mmp-9 expression. Sahin A, etal., Int J Mol Med. 2005 May;15(5):771-6.
29. Dominant-negative inhibition of Ets 1 suppresses tumor growth, invasion and migration in rat C6 glioma cells and reveals differentially expressed Ets 1 target genes. Sahin A, etal., Int J Oncol. 2009 Feb;34(2):377-89.
30. Ets-1 stimulates platelet-derived growth factor A-chain gene transcription and vascular smooth muscle cell growth via cooperative interactions with Sp1. Santiago FS and Khachigian LM, Circ Res. 2004 Sep 3;95(5):479-87. Epub 2004 Aug 5.
31. Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells. Seeger FH, etal., PLoS One. 2009;4(2):e4529. Epub 2009 Feb 19.
32. Expression and function of Ets-1 during experimental acute renal failure in rats. Tanaka H, etal., J Am Soc Nephrol. 2004 Dec;15(12):3083-92.
33. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
34. Selective repression of rat prolactin gene by stable expression of dominant-negative Ets in GH4 pituitary cells. Tentler JJ, etal., Endocrine 2003 Feb-Mar;20(1-2):3-12.
35. Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential. Vairaktaris E, etal., In Vivo. 2007 Jul-Aug;21(4):615-21.
36. Thrombin potentiates D-aspartate efflux from cultured astrocytes under conditions of K homeostasis disruption. Vazquez-Juarez E, etal., J Neurochem. 2009 Oct 3.
37. Expression and localization of transcription factor Ets-1 in the rat ovary during the estrous cycle and pregnancy. Xiao X, etal., Fertil Steril. 2009 May;91(5 Suppl):1998-2005. Epub 2008 Apr 25.
38. Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter. Zhang C, etal., J Biol Chem 2003 Jul 25;278(30):27903-9. Epub 2003 May 9.
Additional References at PubMed
PMID:1298911   PMID:1409581   PMID:7753825   PMID:7774816   PMID:8620536   PMID:9266972   PMID:10698492   PMID:11909962   PMID:12119294   PMID:12464608   PMID:12477932   PMID:14730627  
PMID:14751865   PMID:15001984   PMID:15247905   PMID:15253715   PMID:15541767   PMID:15592518   PMID:15994560   PMID:16189269   PMID:17505916   PMID:17658891   PMID:18712054   PMID:20598359  
PMID:21081489   PMID:21310411   PMID:21711453   PMID:22294049   PMID:23246490   PMID:24287791   PMID:25609649   PMID:25624342   PMID:26617730   PMID:26658785   PMID:27349435   PMID:28502794  
PMID:28696249   PMID:29856744   PMID:35338235  


Genomics

Comparative Map Data
Ets1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2831,045,909 - 31,168,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl831,045,945 - 31,168,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx835,176,570 - 35,239,049 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0833,471,056 - 33,533,529 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0831,333,929 - 31,396,429 (+)NCBIRnor_WKY
Rnor_6.0833,756,634 - 33,879,625 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,816,386 - 33,879,625 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,798,598 - 33,921,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,481,694 - 32,545,237 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1832,490,458 - 32,553,970 (+)NCBI
Celera832,555,513 - 32,617,691 (+)NCBICelera
RH 3.4 Map8268.3RGD
Cytogenetic Map8q21NCBI
ETS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811128,458,765 - 128,587,558 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11128,458,761 - 128,587,558 (-)EnsemblGRCh38hg38GRCh38
GRCh3711128,328,660 - 128,457,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611127,833,870 - 127,897,371 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411127,833,871 - 127,897,371NCBI
Celera11125,494,962 - 125,623,626 (-)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11124,277,062 - 124,405,816 (-)NCBIHuRef
CHM1_111128,214,474 - 128,343,214 (-)NCBICHM1_1
T2T-CHM13v2.011128,492,108 - 128,620,806 (-)NCBIT2T-CHM13v2.0
Ets1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39932,547,501 - 32,669,116 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl932,547,517 - 32,669,116 (+)EnsemblGRCm39 Ensembl
GRCm38932,636,241 - 32,757,820 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl932,636,221 - 32,757,820 (+)EnsemblGRCm38mm10GRCm38
MGSCv37932,503,627 - 32,565,405 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36932,445,607 - 32,507,385 (+)NCBIMGSCv36mm8
Celera929,958,312 - 30,019,948 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.97NCBI
Ets1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541229,432,482 - 29,545,580 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541229,433,730 - 29,602,389 (-)NCBIChiLan1.0ChiLan1.0
ETS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111127,174,721 - 127,302,834 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11127,174,721 - 127,288,673 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011123,272,111 - 123,400,413 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ETS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.156,059,023 - 6,189,516 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl56,058,935 - 6,186,232 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha56,115,844 - 6,246,105 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.056,012,469 - 6,143,424 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl56,012,519 - 6,143,417 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.156,071,677 - 6,202,786 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.056,053,510 - 6,184,305 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.056,084,005 - 6,215,159 (+)NCBIUU_Cfam_GSD_1.0
Ets1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947110,654,883 - 110,785,267 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365723,730,327 - 3,795,625 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365723,728,971 - 3,795,612 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl955,377,266 - 55,512,115 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1955,377,264 - 55,512,180 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2961,508,893 - 61,540,092 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ETS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11119,588,476 - 119,736,623 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1119,588,448 - 119,652,299 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660436,367,577 - 6,503,784 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ets1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248122,795,686 - 2,920,274 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248122,795,961 - 2,920,263 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ets1
1416 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1406
Count of miRNA genes:334
Interacting mature miRNAs:430
Transcripts:ENSRNOT00000011925, ENSRNOT00000064687
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83084815440713225Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat

Markers in Region
D8Wox17  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8q21UniSTS
D8Rat221  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,166,581 - 31,166,723 (+)MAPPERmRatBN7.2
Rnor_6.0833,878,197 - 33,878,338NCBIRnor6.0
Rnor_5.0833,920,165 - 33,920,306UniSTSRnor5.0
RGSC_v3.4832,543,808 - 32,543,950RGDRGSC3.4
RGSC_v3.4832,543,809 - 32,543,950UniSTSRGSC3.4
RGSC_v3.1832,552,574 - 32,552,716RGD
Celera832,616,262 - 32,616,403UniSTS
SHRSP x BN Map823.06UniSTS
SHRSP x BN Map823.06RGD
FHH x ACI Map824.3RGD
Cytogenetic Map8q21UniSTS
D8Wox27  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,166,626 - 31,166,775 (+)MAPPERmRatBN7.2
Rnor_6.0833,878,242 - 33,878,390NCBIRnor6.0
Rnor_5.0833,920,210 - 33,920,358UniSTSRnor5.0
RGSC_v3.4832,543,854 - 32,544,002UniSTSRGSC3.4
Celera832,616,307 - 32,616,455UniSTS
Cytogenetic Map8q21UniSTS
RH94701  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,105,420 - 31,105,591 (+)MAPPERmRatBN7.2
Rnor_6.0833,816,394 - 33,816,564NCBIRnor6.0
Rnor_5.0833,858,355 - 33,858,525UniSTSRnor5.0
RGSC_v3.4832,481,702 - 32,481,872UniSTSRGSC3.4
Celera832,555,521 - 32,555,691UniSTS
Cytogenetic Map8q21UniSTS
AI196000  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,167,733 - 31,167,884 (+)MAPPERmRatBN7.2
Rnor_6.0833,879,349 - 33,879,499NCBIRnor6.0
Rnor_5.0833,921,317 - 33,921,467UniSTSRnor5.0
RGSC_v3.4832,544,961 - 32,545,111UniSTSRGSC3.4
Celera832,617,414 - 32,617,565UniSTS
Cytogenetic Map8q21UniSTS
RH138700  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,162,935 - 31,164,432 (+)MAPPERmRatBN7.2
Rnor_6.0833,874,551 - 33,876,047NCBIRnor6.0
Rnor_5.0833,916,519 - 33,918,015UniSTSRnor5.0
RGSC_v3.4832,540,163 - 32,541,659UniSTSRGSC3.4
Celera832,612,613 - 32,614,112UniSTS
RH 3.4 Map8255.7UniSTS
Cytogenetic Map8q21UniSTS
ETS1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,167,800 - 31,167,913 (+)MAPPERmRatBN7.2
Rnor_6.0833,879,416 - 33,879,528NCBIRnor6.0
Rnor_5.0833,921,384 - 33,921,496UniSTSRnor5.0
RGSC_v3.4832,545,028 - 32,545,140UniSTSRGSC3.4
Celera832,617,481 - 32,617,594UniSTS
Cytogenetic Map8q21UniSTS
RH94700  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,166,136 - 31,166,327 (+)MAPPERmRatBN7.2
Rnor_6.0833,877,752 - 33,877,942NCBIRnor6.0
Rnor_5.0833,919,720 - 33,919,910UniSTSRnor5.0
RGSC_v3.4832,543,364 - 32,543,554UniSTSRGSC3.4
Celera832,615,817 - 32,616,007UniSTS
RH 3.4 Map8268.3UniSTS
Cytogenetic Map8q21UniSTS
RH142868  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,141,949 - 31,142,099 (+)MAPPERmRatBN7.2
Rnor_6.0833,853,566 - 33,853,715NCBIRnor6.0
Rnor_5.0833,895,534 - 33,895,683UniSTSRnor5.0
RGSC_v3.4832,519,177 - 32,519,326UniSTSRGSC3.4
Celera832,591,776 - 32,591,925UniSTS
RH 3.4 Map8257.6UniSTS
Cytogenetic Map8q21UniSTS
RH94408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,164,988 - 31,165,085 (+)MAPPERmRatBN7.2
Rnor_6.0833,876,604 - 33,876,700NCBIRnor6.0
Rnor_5.0833,918,572 - 33,918,668UniSTSRnor5.0
RGSC_v3.4832,542,216 - 32,542,312UniSTSRGSC3.4
Celera832,614,669 - 32,614,765UniSTS
Cytogenetic Map8q21UniSTS
RH139077  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,141,944 - 31,142,094 (+)MAPPERmRatBN7.2
Rnor_6.0833,853,561 - 33,853,710NCBIRnor6.0
Rnor_5.0833,895,529 - 33,895,678UniSTSRnor5.0
RGSC_v3.4832,519,172 - 32,519,321UniSTSRGSC3.4
Celera832,591,771 - 32,591,920UniSTS
Cytogenetic Map8q21UniSTS
WS29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,167,790 - 31,167,922 (+)MAPPERmRatBN7.2
Rnor_6.0833,879,406 - 33,879,537NCBIRnor6.0
Rnor_5.0833,921,374 - 33,921,505UniSTSRnor5.0
RGSC_v3.4832,545,018 - 32,545,149UniSTSRGSC3.4
Celera832,617,471 - 32,617,603UniSTS
Cytogenetic Map8q21UniSTS


Genetic Models
This gene Ets1 is modified in the following models/strains

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 43 56 40 19 40 6 7 55 35 34 11 6
Low 1 1 1 1 2 4 19 7 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011925   ⟹   ENSRNOP00000011925
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl831,105,413 - 31,168,010 (+)Ensembl
Rnor_6.0 Ensembl833,816,386 - 33,879,625 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099064   ⟹   ENSRNOP00000090638
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl831,105,375 - 31,164,406 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099961   ⟹   ENSRNOP00000090577
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl831,105,505 - 31,168,010 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102138   ⟹   ENSRNOP00000079875
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl831,105,692 - 31,168,010 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111888   ⟹   ENSRNOP00000083232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl831,045,945 - 31,168,010 (+)Ensembl
RefSeq Acc Id: NM_012555   ⟹   NP_036687
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2831,105,413 - 31,168,010 (+)NCBI
Rnor_6.0833,816,386 - 33,879,625 (+)NCBI
Rnor_5.0833,798,598 - 33,921,593 (+)NCBI
RGSC_v3.4832,481,694 - 32,545,237 (+)RGD
Celera832,555,513 - 32,617,691 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242752   ⟹   XP_006242814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2831,105,344 - 31,168,010 (+)NCBI
Rnor_6.0833,816,338 - 33,879,625 (+)NCBI
Rnor_5.0833,798,598 - 33,921,593 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595451   ⟹   XP_017450940
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2831,045,909 - 31,168,010 (+)NCBI
Rnor_6.0833,756,634 - 33,879,625 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039080790   ⟹   XP_038936718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2831,045,909 - 31,168,010 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036687   ⟸   NM_012555
- UniProtKB: Q3T1H1 (UniProtKB/Swiss-Prot),   P41156 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006242814   ⟸   XM_006242752
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AEK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450940   ⟸   XM_017595451
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000011925   ⟸   ENSRNOT00000011925
RefSeq Acc Id: XP_038936718   ⟸   XM_039080790
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000090577   ⟸   ENSRNOT00000099961
RefSeq Acc Id: ENSRNOP00000079875   ⟸   ENSRNOT00000102138
RefSeq Acc Id: ENSRNOP00000083232   ⟸   ENSRNOT00000111888
RefSeq Acc Id: ENSRNOP00000090638   ⟸   ENSRNOT00000099064
Protein Domains
ETS   PNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P41156-F1-model_v2 AlphaFold P41156 1-441 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695833
Promoter ID:EPDNEW_R6357
Type:initiation region
Name:Ets1_1
Description:ETS proto-oncogene 1, transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0833,816,400 - 33,816,460EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2583 AgrOrtholog
BioCyc Gene G2FUF-31233 BioCyc
Ensembl Genes ENSRNOG00000008941 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011925 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000079875.1 UniProtKB/TrEMBL
  ENSRNOP00000083232 ENTREZGENE
  ENSRNOP00000083232.1 UniProtKB/TrEMBL
  ENSRNOP00000090577 ENTREZGENE
  ENSRNOP00000090577.1 UniProtKB/TrEMBL
  ENSRNOP00000090638.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011925 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000099064.1 UniProtKB/TrEMBL
  ENSRNOT00000099961 ENTREZGENE
  ENSRNOT00000099961.1 UniProtKB/TrEMBL
  ENSRNOT00000102138.1 UniProtKB/TrEMBL
  ENSRNOT00000111888 ENTREZGENE
  ENSRNOT00000111888.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7939228 IMAGE-MGC_LOAD
InterPro Ets1_N_flank UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ets_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pointed_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_PNT-ETS-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transform_prot_C-ets UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24356 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124638 IMAGE-MGC_LOAD
NCBI Gene 24356 ENTREZGENE
PANTHER PTHR11849 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ets UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ets1_N_flank UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_PNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ets1 PhenoGen
PIRSF Transforming_factor_C-ets UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ETS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_PNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218013
UniProt A0A8I5ZPA0_RAT UniProtKB/TrEMBL
  A0A8I5ZWK1_RAT UniProtKB/TrEMBL
  A0A8I6AE74_RAT UniProtKB/TrEMBL
  A0A8I6AEK6 ENTREZGENE, UniProtKB/TrEMBL
  ETS1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q3T1H1 ENTREZGENE
UniProt Secondary Q3T1H1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-11-06 Ets1  v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)    Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)  Name updated 625702 APPROVED
2002-06-10 Ets1  Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)      Symbol and Name status set to approved 70586 APPROVED