(+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of EGFR mRNA CTD PMID:17971868 (+)-Tetrandrine decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 tetrandrine results in decreased phosphorylation of EGFR protein CTD PMID:30549224 (-)-epigallocatechin 3-gallate multiple interactions ISO EGFR (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EGFR mRNA more ... CTD PMID:17616711 more ... (-)-epigallocatechin 3-gallate multiple interactions ISO Egfr (Mus musculus) 6480464 epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] CTD PMID:27058323 (-)-epigallocatechin 3-gallate increases expression ISO EGFR (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of EGFR mRNA CTD PMID:22079256 (1->4)-beta-D-glucan multiple interactions ISO Egfr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EGFR mRNA CTD PMID:36331819 (20R)-protopanaxadiol decreases activity ISO EGFR (Homo sapiens) 6480464 protopanaxadiol results in decreased activity of EGFR protein CTD PMID:31805304 (20R)-protopanaxadiol multiple interactions ISO EGFR (Homo sapiens) 6480464 protopanaxadiol results in decreased expression of and results in increased phosphorylation of EGFR protein CTD PMID:31805304 (20S)-ginsenoside Rg3 multiple interactions ISO EGFR (Homo sapiens) 6480464 EGF protein promotes the reaction [ginsenoside Rg3 affects the phosphorylation of EGFR protein] more ... CTD PMID:25824408 (20S)-ginsenoside Rg3 affects phosphorylation ISO EGFR (Homo sapiens) 6480464 ginsenoside Rg3 affects the phosphorylation of EGFR protein CTD PMID:25824408 (R)-noradrenaline multiple interactions EXP 6480464 EGFR protein inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form] CTD PMID:19168439 (S)-naringenin multiple interactions ISO EGFR (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of EGFR mRNA more ... CTD PMID:25866363 and PMID:36235125 (S)-nicotine increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of EGFR protein CTD PMID:14569062 (S)-nicotine multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Nicotine results in increased phosphorylation of EGFR protein] CTD PMID:14569062 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of EGFR mRNA CTD PMID:11478936 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases phosphorylation ISO EGFR (Homo sapiens) 6480464 2 more ... CTD PMID:28426875 1,2,3,4,7,8-Hexachlorodibenzofuran decreases activity ISO Egfr (Mus musculus) 6480464 1 more ... CTD PMID:2718174 1,2-dichloroethane decreases expression ISO Egfr (Mus musculus) 6480464 ethylene dichloride results in decreased expression of EGFR mRNA CTD PMID:28189721 and PMID:28960355 1,2-dimethylhydrazine decreases expression ISO Egfr (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of EGFR mRNA CTD PMID:22206623 1,2-naphthoquinone multiple interactions ISO EGFR (Homo sapiens) 6480464 1 more ... CTD PMID:24067727 and PMID:33814511 1,2-naphthoquinone increases phosphorylation ISO EGFR (Homo sapiens) 6480464 1 and 2-naphthoquinone results in increased phosphorylation of EGFR protein CTD PMID:33814511 1,4-benzoquinone multiple interactions ISO EGFR (Homo sapiens) 6480464 quinone promotes the reaction [1 and 4-naphthoquinone results in increased phosphorylation of EGFR protein] CTD PMID:33814511 1,4-naphthoquinone multiple interactions ISO EGFR (Homo sapiens) 6480464 1 more ... CTD PMID:33814511 1,4-naphthoquinone increases phosphorylation ISO EGFR (Homo sapiens) 6480464 1 and 4-naphthoquinone results in increased phosphorylation of EGFR protein CTD PMID:33814511 1-chloro-2,4-dinitrobenzene affects binding ISO EGFR (Homo sapiens) 6480464 Dinitrochlorobenzene binds to EGFR protein CTD PMID:32991956 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 lysophosphatidic acid results in increased phosphorylation of EGFR protein CTD PMID:23127547 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO EGFR (Homo sapiens) 6480464 GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] more ... CTD PMID:23127547 16,16-dimethylprostaglandin E2 multiple interactions ISO Egfr (Mus musculus) 6480464 EGFR affects the reaction [16 and 16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein] CTD PMID:15578100 17alpha-ethynylestradiol increases expression ISO Egfr (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of EGFR mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EGFR protein CTD PMID:2197011 and PMID:2786453 17alpha-ethynylestradiol increases stability EXP 6480464 Ethinyl Estradiol results in increased stability of EGFR protein CTD PMID:2197011 17alpha-ethynylestradiol affects expression ISO Egfr (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of EGFR mRNA CTD PMID:17555576 17beta-estradiol multiple interactions ISO Egfr (Mus musculus) 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of EGFR mRNA] more ... CTD PMID:22414604 and PMID:25210133 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of EGFR mRNA CTD PMID:32145629 17beta-estradiol increases activity ISO EGFR (Homo sapiens) 6480464 Estradiol results in increased activity of EGFR protein CTD PMID:15802018 17beta-estradiol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of EGFR protein CTD PMID:20005069 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of EGFR mRNA CTD PMID:20068009 and PMID:31119341 17beta-estradiol multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein] CTD PMID:8888411 17beta-estradiol increases expression ISO EGFR (Homo sapiens) 6480464 Estradiol results in increased expression of EGFR mRNA CTD PMID:19619570 and PMID:31614463 17beta-estradiol decreases expression ISO EGFR (Homo sapiens) 6480464 Estradiol results in decreased expression of EGFR mRNA and Estradiol results in decreased expression of EGFR protein CTD PMID:20005069 17beta-estradiol multiple interactions ISO EGFR (Homo sapiens) 6480464 4-(6-bromo-1 more ... CTD PMID:17622325 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of EGFR mRNA and Estradiol results in increased expression of EGFR protein CTD PMID:35192832 and PMID:8888411 17beta-estradiol increases expression ISO Egfr (Mus musculus) 6480464 Estradiol results in increased expression of EGFR mRNA CTD PMID:25210133 17beta-estradiol 17-glucosiduronic acid multiple interactions EXP 6480464 EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein] more ... CTD PMID:25813982 17beta-estradiol 3-benzoate increases expression EXP 6480464 estradiol 3-benzoate results in increased expression of EGFR protein CTD PMID:15778002 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions EXP 6480464 Metribolone results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:17272394 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO EGFR (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of EGFR mRNA CTD PMID:29581250 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO Egfr (Mus musculus) 6480464 [cypermethrin results in decreased susceptibility to Dihydrotestosterone] which results in decreased phosphorylation of EGFR protein CTD PMID:30974244 2,2',4,4',5,5'-hexachlorobiphenyl affects localization ISO EGFR (Homo sapiens) 6480464 2 more ... CTD PMID:19632255 2,2',4,4',5,5'-hexachlorobiphenyl affects binding ISO EGFR (Homo sapiens) 6480464 2 more ... CTD PMID:29329451 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO EGFR (Homo sapiens) 6480464 2 more ... CTD PMID:29329451 2,2',4,4',5,5'-hexachlorobiphenyl increases phosphorylation ISO EGFR (Homo sapiens) 6480464 2 more ... CTD PMID:19632255 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Egfr (Mus musculus) 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO EGFR (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,3,4,7,8-Pentachlorodibenzofuran decreases activity ISO Egfr (Mus musculus) 6480464 2 more ... CTD PMID:2718174 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO EGFR (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR mRNA more ... CTD PMID:11309286 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases metabolic processing EXP 6480464 Tetrachlorodibenzodioxin results in increased metabolism of EGFR gene CTD PMID:32277265 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Egfr (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR mRNA CTD PMID:14708085 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Egfr (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of EGFR mRNA CTD PMID:21570461 and PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Egfr (Mus musculus) 6480464 CSK protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] more ... CTD PMID:6309801 and PMID:9664232 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EGFR protein CTD PMID:10401681 and PMID:15592923 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO EGFR (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR CTD PMID:1336723 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EGFR protein CTD PMID:20971882 and PMID:26971374 2,3,7,8-tetrachlorodibenzodioxine affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:9163677 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EGFR mRNA CTD PMID:22298810 and PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO EGFR (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA and Tetrachlorodibenzodioxin results in increased expression of EGFR protein CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Egfr (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA and Tetrachlorodibenzodioxin results in increased expression of EGFR protein CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR mRNA and Tetrachlorodibenzodioxin results in decreased expression of EGFR protein CTD PMID:20959002 and PMID:8403215 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR protein more ... CTD PMID:11752688 more ... 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,5-hexanedione increases expression EXP 6480464 2 and 5-hexanedione results in increased expression of EGFR mRNA CTD PMID:16141653 2-acetamidofluorene multiple interactions EXP 6480464 2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:10900465 2-acetamidofluorene decreases expression EXP 6480464 2-Acetylaminofluorene results in decreased expression of EGFR mRNA CTD PMID:22213190 2-deoxy-D-glucose multiple interactions ISO EGFR (Homo sapiens) 6480464 AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 2-deoxy-D-glucose increases import ISO EGFR (Homo sapiens) 6480464 EGFR protein mutant form results in increased import of Deoxyglucose CTD PMID:19625624 2-hydroxypropanoic acid decreases expression ISO EGFR (Homo sapiens) 6480464 Lactic Acid results in decreased expression of EGFR mRNA CTD PMID:30851411 2-methoxy-17beta-estradiol decreases expression ISO EGFR (Homo sapiens) 6480464 2-Methoxyestradiol results in decreased expression of EGFR mRNA and 2-Methoxyestradiol results in decreased expression of EGFR protein CTD PMID:30779072 2-nitrotoluene decreases expression ISO Egfr (Mus musculus) 6480464 2-nitrotoluene results in decreased expression of EGFR mRNA CTD PMID:15618236 3',5'-cyclic AMP multiple interactions ISO Egfr (Mus musculus) 6480464 [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO EGFR (Homo sapiens) 6480464 3 more ... CTD PMID:29329451 3,3',4,4',5-pentachlorobiphenyl affects binding ISO EGFR (Homo sapiens) 6480464 3 more ... CTD PMID:29329451 3,3',5,5'-tetrabromobisphenol A increases phosphorylation ISO EGFR (Homo sapiens) 6480464 tetrabromobisphenol A results in increased phosphorylation of EGFR protein CTD PMID:26718265 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO EGFR (Homo sapiens) 6480464 bisindolylmaleimide I inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein] and bisindolylmaleimide I inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein] CTD PMID:15723263 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of EGFR mRNA CTD PMID:28522335 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of EGFR mRNA CTD PMID:29094188 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of EGFR mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to [Epirubicin co-treated with CMF regimen] CTD PMID:18768436 4,4'-diaminodiphenylmethane increases expression ISO Egfr (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of EGFR mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions ISO EGFR (Homo sapiens) 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of EGFR gene more ... CTD PMID:31601247 and PMID:33605785 4,4'-sulfonyldiphenol increases expression ISO EGFR (Homo sapiens) 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of EGFR protein CTD PMID:31945527 and PMID:34186270 4,4'-sulfonyldiphenol increases expression ISO Egfr (Mus musculus) 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of EGFR mRNA CTD PMID:30951980 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation ISO EGFR (Homo sapiens) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein CTD PMID:16671086 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO EGFR (Homo sapiens) 6480464 Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein] CTD PMID:16671086 4-hydroxyphenyl retinamide increases expression ISO EGFR (Homo sapiens) 6480464 Fenretinide results in increased expression of EGFR mRNA CTD PMID:16570282 4-hydroxyphenyl retinamide decreases expression ISO Egfr (Mus musculus) 6480464 Fenretinide results in decreased expression of EGFR mRNA CTD PMID:28973697 4-nitrophenol increases expression ISO Egfr (Mus musculus) 6480464 4-nitrophenol results in increased expression of EGFR mRNA CTD PMID:34673133 4-nitrotoluene decreases expression ISO Egfr (Mus musculus) 6480464 4-nitrotoluene results in decreased expression of EGFR protein CTD PMID:15618236 4-tert-Octylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 4-tert-Octylphenol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of EGFR protein CTD PMID:32466334 4-vinylcyclohexene dioxide affects expression ISO Egfr (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of EGFR mRNA CTD PMID:20829426 5,6alpha-epoxy-5alpha-cholestan-3beta-ol increases phosphorylation EXP 6480464 cholesterol alpha-oxide results in increased phosphorylation of EGFR protein CTD PMID:20466046 5-aza-2'-deoxycytidine increases expression ISO EGFR (Homo sapiens) 6480464 Decitabine results in increased expression of EGFR mRNA CTD PMID:19151715 5-chloro-7-iodoquinolin-8-ol multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 5-fluorouracil decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene polymorphism results in decreased susceptibility to Fluorouracil CTD PMID:19217205 5-fluorouracil decreases expression ISO EGFR (Homo sapiens) 6480464 Fluorouracil results in decreased expression of EGFR protein CTD PMID:17918158 and PMID:17982676 5-fluorouracil increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Fluorouracil results in increased phosphorylation of EGFR protein CTD PMID:18794807 5-fluorouracil affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Fluorouracil CTD PMID:16836928 and PMID:17169374 5-fluorouracil multiple interactions ISO EGFR (Homo sapiens) 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA more ... CTD PMID:15737843 more ... 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO EGFR (Homo sapiens) 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:25625231 and PMID:30364229 6-chrysenamine multiple interactions ISO Egfr (Mus musculus) 6480464 6-chrysenamine inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of EGFR mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of EGFR mRNA CTD PMID:30047161 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:36863560 7,12-dimethyltetraphene decreases expression ISO Egfr (Mus musculus) 6480464 9 more ... CTD PMID:32553695 7-ketocholesterol increases phosphorylation EXP 6480464 7-ketocholesterol results in increased phosphorylation of EGFR protein CTD PMID:20466046 8-Br-cAMP increases expression ISO EGFR (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGFR mRNA CTD PMID:22079614 9,10-phenanthroquinone multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:32493877 9,10-phenanthroquinone increases phosphorylation ISO EGFR (Homo sapiens) 6480464 9 and 10-phenanthrenequinone results in increased phosphorylation of EGFR protein CTD PMID:32493877 9-cis-retinoic acid decreases expression ISO EGFR (Homo sapiens) 6480464 Alitretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of EGFR mRNA CTD PMID:31881176 acetylsalicylic acid increases expression ISO EGFR (Homo sapiens) 6480464 Aspirin results in increased expression of EGFR mRNA CTD PMID:15456535 acrolein increases activity ISO EGFR (Homo sapiens) 6480464 Acrolein results in increased activity of EGFR protein CTD PMID:11329622 acrolein increases phosphorylation ISO Egfr (Mus musculus) 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:20153347 acrolein increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:11329622 and PMID:15531749 acrolein multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]] and Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:20359552 acrolein multiple interactions ISO EGFR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of EGFR mRNA more ... CTD PMID:15531749 and PMID:32699268 acrylamide affects phosphorylation ISO EGFR (Homo sapiens) 6480464 Acrylamide analog affects the phosphorylation of EGFR protein CTD PMID:11462982 acrylamide increases expression ISO EGFR (Homo sapiens) 6480464 Acrylamide results in increased expression of EGFR protein CTD PMID:24508477 acrylamide multiple interactions ISO EGFR (Homo sapiens) 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein] and epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of EGFR protein] CTD PMID:24508477 acrylamide decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Acrylamide analog results in decreased phosphorylation of EGFR protein CTD PMID:10753475 acteoside decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 acteoside results in decreased phosphorylation of EGFR protein CTD PMID:21756928 and PMID:21967610 acteoside multiple interactions ISO EGFR (Homo sapiens) 6480464 acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein] more ... CTD PMID:21756928 and PMID:21967610 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein] and Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 afatinib decreases activity ISO EGFR (Homo sapiens) 6480464 afatinib results in decreased activity of EGFR protein and afatinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 and PMID:22242139 afatinib decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 afatinib results in decreased phosphorylation of EGFR protein CTD PMID:28787001 afimoxifene decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein results in decreased susceptibility to afimoxifene and EGFR results in decreased susceptibility to afimoxifene CTD PMID:18351453 and PMID:21233418 AH23848 multiple interactions ISO EGFR (Homo sapiens) 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein] and [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of and results in decreased expression of EGFR protein CTD PMID:19407222 AICA ribonucleotide multiple interactions ISO EGFR (Homo sapiens) 6480464 AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of EGFR mRNA CTD PMID:11507004 all-trans-4-oxoretinoic acid decreases expression ISO EGFR (Homo sapiens) 6480464 4-oxoretinoic acid results in decreased expression of EGFR mRNA CTD PMID:15982314 all-trans-retinoic acid decreases expression ISO EGFR (Homo sapiens) 6480464 Tretinoin metabolite results in decreased expression of EGFR mRNA and Tretinoin results in decreased expression of EGFR protein CTD PMID:15970678 more ... all-trans-retinoic acid increases expression ISO EGFR (Homo sapiens) 6480464 Tretinoin results in increased expression of EGFR mRNA CTD PMID:21934132 and PMID:34742744 all-trans-retinoic acid increases phosphorylation ISO Egfr (Mus musculus) 6480464 Tretinoin results in increased phosphorylation of EGFR protein CTD PMID:16357442 all-trans-retinoic acid increases expression ISO Egfr (Mus musculus) 6480464 Tretinoin results in increased expression of EGFR mRNA CTD PMID:16604517 all-trans-retinoic acid multiple interactions ISO Egfr (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EGFR mRNA and HBEGF protein promotes the reaction [Tretinoin results in increased phosphorylation of EGFR protein] CTD PMID:16357442 and PMID:30951980 all-trans-retinol increases expression EXP 6480464 Vitamin A deficiency results in increased expression of EGFR mRNA CTD PMID:7519440 alpha-naphthoflavone multiple interactions ISO EGFR (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:17934341 alpha-pinene multiple interactions ISO EGFR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of EGFR mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of EGFR mRNA CTD PMID:32699268 alprenolol multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Alprenolol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 alprenolol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 [Alprenolol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein CTD PMID:18787115 aluminium oxide increases expression ISO EGFR (Homo sapiens) 6480464 Aluminum Oxide results in increased expression of EGFR mRNA CTD PMID:19464052 AM-251 multiple interactions ISO EGFR (Homo sapiens) 6480464 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein] more ... CTD PMID:27423937 AM-251 increases expression ISO EGFR (Homo sapiens) 6480464 AM 251 results in increased expression of EGFR protein CTD PMID:27423937 amiodarone multiple interactions ISO EGFR (Homo sapiens) 6480464 Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] and RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]] CTD PMID:26515726 amiodarone decreases phosphorylation ISO Egfr (Mus musculus) 6480464 Amiodarone results in decreased phosphorylation of EGFR protein CTD PMID:26515726 amiodarone decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Amiodarone results in decreased phosphorylation of EGFR protein CTD PMID:26515726 amiodarone multiple interactions ISO Egfr (Mus musculus) 6480464 Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein] CTD PMID:26515726 amiodarone decreases expression ISO Egfr (Mus musculus) 6480464 Amiodarone results in decreased expression of EGFR mRNA CTD PMID:24535564 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of EGFR mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EGFR mRNA CTD PMID:16483693 ammonium chloride decreases expression EXP 6480464 Ammonium Chloride results in decreased expression of EGFR protein CTD PMID:16483693 amosite asbestos decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Asbestos and Amosite results in decreased phosphorylation of EGFR protein CTD PMID:15626777 amosite asbestos increases expression EXP 6480464 Asbestos and Amosite results in increased expression of EGFR mRNA CTD PMID:22251266 amphibole asbestos increases expression EXP 6480464 Asbestos and Amphibole results in increased expression of EGFR mRNA CTD PMID:22251266 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression ISO EGFR (Homo sapiens) 6480464 pyrazolanthrone results in decreased expression of EGFR mRNA and pyrazolanthrone results in decreased expression of EGFR protein CTD PMID:15923621 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression EXP 6480464 pyrazolanthrone results in decreased expression of EGFR mRNA and pyrazolanthrone results in decreased expression of EGFR protein CTD PMID:18332871 antimonite increases expression ISO EGFR (Homo sapiens) 6480464 antimonite results in increased expression of EGFR protein CTD PMID:17400267 antirheumatic drug decreases expression ISO EGFR (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of EGFR mRNA CTD PMID:24449571 ANTU increases expression EXP 6480464 alpha-naphthyl thiourea results in increased expression of EGFR mRNA CTD PMID:10755703 apocynin multiple interactions ISO EGFR (Homo sapiens) 6480464 acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 arachidonic acid multiple interactions EXP 6480464 5 more ... CTD PMID:15525798 arecoline multiple interactions ISO Egfr (Mus musculus) 6480464 [Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased phosphorylation of EGFR protein more ... CTD PMID:26464283 aristolochic acid A decreases expression ISO EGFR (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of EGFR mRNA CTD PMID:33212167 arsane increases expression ISO EGFR (Homo sapiens) 6480464 Arsenic results in increased expression of EGFR mRNA and Arsenic results in increased expression of EGFR protein alternative form CTD PMID:17453740 and PMID:19945496 arsane affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene SNP affects the susceptibility to Arsenic CTD PMID:31864032 arsane multiple interactions ISO Egfr (Mus musculus) 6480464 Arsenic results in increased phosphorylation of and affects the localization of EGFR protein and RTKI cpd inhibits the reaction [Arsenic affects the localization of EGFR protein] CTD PMID:32159786 arsane decreases expression ISO EGFR (Homo sapiens) 6480464 Arsenic results in decreased expression of EGFR mRNA CTD PMID:31739468 arsane multiple interactions ISO EGFR (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 arsenic acid increases phosphorylation ISO EGFR (Homo sapiens) 6480464 arsenic acid results in increased phosphorylation of EGFR protein CTD PMID:14674888 arsenic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the reaction [arsenic acid results in increased activity of MAPK1 protein] and EGFR protein affects the reaction [arsenic acid results in increased activity of MAPK3 protein] CTD PMID:14674888 arsenic atom increases expression ISO EGFR (Homo sapiens) 6480464 Arsenic results in increased expression of EGFR mRNA and Arsenic results in increased expression of EGFR protein alternative form CTD PMID:17453740 and PMID:19945496 arsenic atom affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene SNP affects the susceptibility to Arsenic CTD PMID:31864032 arsenic atom multiple interactions ISO Egfr (Mus musculus) 6480464 Arsenic results in increased phosphorylation of and affects the localization of EGFR protein and RTKI cpd inhibits the reaction [Arsenic affects the localization of EGFR protein] CTD PMID:32159786 arsenic atom multiple interactions ISO EGFR (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 arsenic atom decreases expression ISO EGFR (Homo sapiens) 6480464 Arsenic results in decreased expression of EGFR mRNA CTD PMID:31739468 arsenite(3-) decreases degradation ISO EGFR (Homo sapiens) 6480464 arsenite results in decreased degradation of EGFR protein CTD PMID:17400267 arsenite(3-) increases methylation ISO EGFR (Homo sapiens) 6480464 arsenite results in increased methylation of EGFR promoter CTD PMID:23974009 arsenite(3-) affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR affects the susceptibility to arsenite CTD PMID:31773452 arsenite(3-) decreases expression ISO Egfr (Mus musculus) 6480464 arsenite results in decreased expression of EGFR mRNA CTD PMID:33053406 arsenite(3-) multiple interactions ISO EGFR (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to EGFR mRNA] more ... CTD PMID:14674888 more ... arsenite(3-) increases phosphorylation ISO EGFR (Homo sapiens) 6480464 arsenite results in increased phosphorylation of EGFR protein CTD PMID:14674888 and PMID:17400267 arsenite(3-) increases expression ISO EGFR (Homo sapiens) 6480464 arsenite results in increased expression of EGFR protein CTD PMID:17400267 arsenous acid decreases expression ISO Egfr (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:23029451 arsenous acid increases expression ISO EGFR (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of EGFR mRNA CTD PMID:22521957 and PMID:29274334 arsenous acid increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of EGFR protein CTD PMID:22532027 arsenous acid multiple interactions ISO EGFR (Homo sapiens) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15961274 more ... arsenous acid decreases expression ISO EGFR (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of EGFR mRNA and Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:20435036 more ... arsenous acid affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Arsenic Trioxide and EGFR protein mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:29535630 and PMID:30237564 arsenous acid multiple interactions ISO Egfr (Mus musculus) 6480464 [Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein CTD PMID:21434348 astragaloside IV multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein and [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 atenolol multiple interactions ISO EGFR (Homo sapiens) 6480464 Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein] CTD PMID:16671086 atorvastatin calcium multiple interactions ISO Egfr (Mus musculus) 6480464 Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:18360054 ATP increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Adenosine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:26104857 ATP multiple interactions ISO EGFR (Homo sapiens) 6480464 sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of EGFR protein] CTD PMID:26104857 atrazine increases expression ISO EGFR (Homo sapiens) 6480464 Atrazine results in increased expression of EGFR mRNA CTD PMID:22378314 atrazine multiple interactions ISO EGFR (Homo sapiens) 6480464 Atrazine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:29329451 atropine multiple interactions ISO EGFR (Homo sapiens) 6480464 Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 avobenzone increases expression ISO EGFR (Homo sapiens) 6480464 avobenzone results in increased expression of EGFR mRNA CTD PMID:31016361 bafilomycin A1 multiple interactions ISO EGFR (Homo sapiens) 6480464 bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 baicalein multiple interactions ISO EGFR (Homo sapiens) 6480464 baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] and MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of EGFR protein] CTD PMID:25625231 and PMID:33838155 baicalein decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 baicalein results in decreased phosphorylation of EGFR protein CTD PMID:33838155 baicalin multiple interactions ISO EGFR (Homo sapiens) 6480464 baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 benzamide decreases activity ISO EGFR (Homo sapiens) 6480464 benzamide analog results in decreased activity of EGFR protein CTD PMID:15186837 benzamidine decreases activity ISO EGFR (Homo sapiens) 6480464 benzamidine analog results in decreased activity of EGFR protein CTD PMID:15186837 benzene decreases expression EXP 6480464 Benzene results in decreased expression of EGFR mRNA CTD PMID:17905399 benzo[a]pyrene increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Benzo(a)pyrene results in increased phosphorylation of EGFR protein CTD PMID:19181443 benzo[a]pyrene affects methylation ISO EGFR (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of EGFR promoter CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO Egfr (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of EGFR 3' UTR and Benzo(a)pyrene results in decreased methylation of EGFR exon CTD PMID:27901495 benzo[a]pyrene increases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein results in increased susceptibility to Benzo(a)pyrene CTD PMID:8608954 benzo[a]pyrene multiple interactions ISO Egfr (Mus musculus) 6480464 AHR protein affects the reaction [Benzo(a)pyrene inhibits the reaction [EGF protein binds to EGFR protein]] and Benzo(a)pyrene inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 benzo[a]pyrene decreases expression ISO Egfr (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in decreased expression of EGFR mRNA and Benzo(a)pyrene results in decreased expression of EGFR mRNA CTD PMID:19770486 more ... benzo[a]pyrene increases expression ISO EGFR (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of EGFR mRNA CTD PMID:19181443 benzo[a]pyrene diol epoxide I multiple interactions ISO EGFR (Homo sapiens) 6480464 7 more ... CTD PMID:22457794 benzo[a]pyrene diol epoxide I multiple interactions ISO Egfr (Mus musculus) 6480464 7 more ... CTD PMID:6309801 benzo[a]pyrene diol epoxide I decreases expression ISO EGFR (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 benzo[b]fluoranthene multiple interactions ISO EGFR (Homo sapiens) 6480464 benzo(b)fluoranthene affects the localization of and results in increased expression of EGFR protein CTD PMID:21776270 benzo[b]fluoranthene decreases expression ISO Egfr (Mus musculus) 6480464 benzo(b)fluoranthene results in decreased expression of EGFR mRNA CTD PMID:26377693 benzoic acid multiple interactions ISO Egfr (Mus musculus) 6480464 Benzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] CTD PMID:26088127 berberine decreases expression ISO EGFR (Homo sapiens) 6480464 Berberine results in decreased expression of EGFR protein CTD PMID:33325633 betulin multiple interactions ISO EGFR (Homo sapiens) 6480464 [Gefitinib co-treated with betulin] results in decreased expression of and results in decreased phosphorylation of EGFR protein CTD PMID:27447558 betulin decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 betulin results in decreased phosphorylation of EGFR protein CTD PMID:27447558 betulinic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:16077934 and PMID:30136359 betulinic acid increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Betulinic Acid results in increased phosphorylation of EGFR protein CTD PMID:16077934 bicalutamide multiple interactions ISO EGFR (Homo sapiens) 6480464 bicalutamide inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to AR protein]] more ... CTD PMID:29383186 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of EGFR mRNA and Diethylhexyl Phthalate results in decreased expression of EGFR protein CTD PMID:2404574 and PMID:34197824 bis(2-ethylhexyl) phthalate increases expression ISO EGFR (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of EGFR mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA more ... CTD PMID:25607892 and PMID:34197824 bisdemethoxycurcumin decreases expression ISO EGFR (Homo sapiens) 6480464 bisdemethoxycurcumin results in decreased expression of EGFR protein modified form CTD PMID:35735092 bisphenol A decreases expression ISO EGFR (Homo sapiens) 6480464 bisphenol A results in decreased expression of EGFR mRNA and bisphenol A results in decreased expression of EGFR protein CTD PMID:20678512 and PMID:31675489 bisphenol A increases phosphorylation ISO Egfr (Mus musculus) 6480464 bisphenol A results in increased phosphorylation of EGFR protein CTD PMID:32353937 bisphenol A decreases methylation ISO EGFR (Homo sapiens) 6480464 bisphenol A results in decreased methylation of EGFR gene CTD PMID:31601247 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EGFR mRNA CTD PMID:32145629 bisphenol A increases expression ISO Egfr (Mus musculus) 6480464 bisphenol A results in increased expression of EGFR mRNA CTD PMID:30951980 and PMID:32353937 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:30816183 bisphenol A increases expression ISO EGFR (Homo sapiens) 6480464 bisphenol A results in increased expression of EGFR mRNA and bisphenol A results in increased expression of EGFR protein CTD PMID:29275510 more ... bisphenol A multiple interactions ISO EGFR (Homo sapiens) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [bisphenol A results in increased phosphorylation of EGFR protein] more ... CTD PMID:28426875 more ... bisphenol A increases phosphorylation ISO EGFR (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of EGFR protein CTD PMID:28426875 more ... bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of EGFR gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EGFR mRNA and bisphenol A results in increased expression of EGFR protein CTD PMID:25181051 and PMID:31771501 bisphenol A decreases expression ISO Egfr (Mus musculus) 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:26063408 and PMID:32156529 bisphenol F increases expression ISO Egfr (Mus musculus) 6480464 bisphenol F results in increased expression of EGFR mRNA CTD PMID:30951980 bisphenol F multiple interactions ISO Egfr (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EGFR mRNA CTD PMID:30951980 bosutinib decreases activity ISO Egfr (Mus musculus) 6480464 bosutinib results in decreased activity of EGFR protein CTD PMID:18385429 butan-1-ol multiple interactions EXP 6480464 1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:11134345 and PMID:15525798 butane-2,3-dione multiple interactions ISO EGFR (Homo sapiens) 6480464 N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine and 2-aminoethylamide inhibits the reaction [Diacetyl results in increased phosphorylation of EGFR protein] CTD PMID:30851105 butane-2,3-dione increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Diacetyl results in increased phosphorylation of EGFR protein CTD PMID:30851105 butylated hydroxyanisole multiple interactions ISO Egfr (Mus musculus) 6480464 Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:21220312 butylated hydroxyanisole multiple interactions ISO EGFR (Homo sapiens) 6480464 Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of EGFR protein] and Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of EGFR protein] CTD PMID:17028263 Butylbenzyl phthalate multiple interactions ISO EGFR (Homo sapiens) 6480464 fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 Butylbenzyl phthalate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 butylbenzyl phthalate results in increased phosphorylation of EGFR protein CTD PMID:22552774 cadmium atom decreases expression ISO Egfr (Mus musculus) 6480464 Cadmium results in decreased expression of EGFR mRNA CTD PMID:22666406 cadmium atom increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Cadmium results in increased phosphorylation of EGFR protein CTD PMID:26514923 cadmium atom multiple interactions ISO EGFR (Homo sapiens) 6480464 4-(6-bromo-1 more ... CTD PMID:25343777 more ... cadmium atom increases activity ISO EGFR (Homo sapiens) 6480464 Cadmium results in increased activity of EGFR protein CTD PMID:25343777 cadmium dichloride increases expression ISO EGFR (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of EGFR and Cadmium Chloride results in increased expression of EGFR mRNA CTD PMID:18560533 more ... cadmium dichloride increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:25118938 and PMID:26385184 cadmium dichloride increases phosphorylation ISO Egfr (Mus musculus) 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:23948867 and PMID:27279585 cadmium dichloride increases expression ISO Egfr (Mus musculus) 6480464 Cadmium Chloride results in increased expression of EGFR mRNA CTD PMID:23948867 cadmium dichloride multiple interactions ISO EGFR (Homo sapiens) 6480464 4-(6-bromo-1 more ... CTD PMID:23673518 more ... cadmium dichloride multiple interactions ISO Egfr (Mus musculus) 6480464 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:23376140 more ... cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:19233221 cadmium dichloride multiple interactions EXP 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] and RTKI cpd inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 calcitriol increases expression ISO EGFR (Homo sapiens) 6480464 Calcitriol results in increased expression of EGFR mRNA CTD PMID:21592394 calcitriol multiple interactions EXP 6480464 Calcitriol results in increased expression of and binds to EGFR protein CTD PMID:3498716 calcitriol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EGFR mRNA CTD PMID:21592394 calcium atom multiple interactions EXP 6480464 Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 calcium silicate increases activity ISO EGFR (Homo sapiens) 6480464 calcium silicate results in increased activity of EGFR protein CTD PMID:21762757 calcium(0) multiple interactions EXP 6480464 Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 canertinib decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Canertinib results in decreased phosphorylation of EGFR protein CTD PMID:15956251 canertinib multiple interactions ISO Egfr (Mus musculus) 6480464 Canertinib inhibits the reaction [Acetaminophen affects the localization of EGFR protein] and Canertinib inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:28123000 canertinib decreases activity ISO EGFR (Homo sapiens) 6480464 Canertinib results in decreased activity of EGFR protein and Canertinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 canertinib multiple interactions ISO EGFR (Homo sapiens) 6480464 Canertinib inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18927496 cannabidiol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA more ... CTD PMID:31250491 more ... capsaicin decreases expression EXP 6480464 Capsaicin results in decreased expression of EGFR protein CTD PMID:14521749 capsaicin multiple interactions ISO Egfr (Mus musculus) 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein more ... CTD PMID:20660715 capsaicin increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Capsaicin results in increased phosphorylation of EGFR protein CTD PMID:20619260 and PMID:20660715 capsaicin decreases expression ISO EGFR (Homo sapiens) 6480464 Capsaicin results in decreased expression of EGFR protein CTD PMID:19855437 capsaicin multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein] more ... CTD PMID:20619260 more ... carbon nanotube affects expression ISO Egfr (Mus musculus) 6480464 Nanotubes and Carbon affects the expression of EGFR mRNA CTD PMID:23845593 carbon nanotube increases expression ISO Egfr (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 carvacrol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 carvacrol results in increased phosphorylation of EGFR protein CTD PMID:32535744 carvacrol multiple interactions ISO EGFR (Homo sapiens) 6480464 KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein] and TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of EGFR protein] CTD PMID:32535744 carvedilol multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 carvedilol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 [carvedilol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein CTD PMID:18787115 casticin decreases expression ISO Egfr (Mus musculus) 6480464 casticin results in decreased expression of EGFR protein CTD PMID:28444820 CEDRELONE decreases expression ISO EGFR (Homo sapiens) 6480464 cedrelone analog results in decreased expression of EGFR protein CTD PMID:31857088 celastrol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Sulfasalazine co-treated with celastrol] affects the expression of EGFR protein and [Sulfasalazine co-treated with celastrol] results in decreased expression of EGFR protein CTD PMID:20007406 celastrol decreases expression ISO EGFR (Homo sapiens) 6480464 celastrol results in decreased expression of EGFR protein CTD PMID:17010675 celecoxib multiple interactions EXP 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein more ... CTD PMID:15309881 and PMID:17908994 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of EGFR mRNA CTD PMID:23125180 chloroquine multiple interactions ISO EGFR (Homo sapiens) 6480464 Chloroquine inhibits the reaction [EGF protein results in decreased expression of EGFR protein] more ... CTD PMID:20056314 more ... chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:22689575 chloroquine decreases expression ISO EGFR (Homo sapiens) 6480464 Chloroquine results in decreased expression of EGFR protein CTD PMID:20332299 chlorothalonil decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 tetrachloroisophthalonitrile results in decreased phosphorylation of EGFR protein CTD PMID:28426875 chlorpyrifos increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Chlorpyrifos results in increased phosphorylation of EGFR protein CTD PMID:26514924 cholesterol multiple interactions ISO Egfr (Mus musculus) 6480464 [Cholesterol co-treated with 1 and 2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of EGFR mRNA CTD PMID:22129739 choline multiple interactions ISO Egfr (Mus musculus) 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 chromium(6+) increases expression ISO EGFR (Homo sapiens) 6480464 chromium hexavalent ion results in increased expression of EGFR mRNA CTD PMID:19616015 chromium(6+) increases phosphorylation ISO Egfr (Mus musculus) 6480464 chromium hexavalent ion results in increased phosphorylation of EGFR protein CTD PMID:25477514 chromium(6+) decreases expression ISO EGFR (Homo sapiens) 6480464 chromium hexavalent ion results in decreased expression of EGFR mRNA CTD PMID:18053681 chrysin multiple interactions ISO EGFR (Homo sapiens) 6480464 chrysin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 ciglitazone multiple interactions ISO EGFR (Homo sapiens) 6480464 ciglitazone inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 ciglitazone decreases expression ISO EGFR (Homo sapiens) 6480464 ciglitazone results in decreased expression of EGFR protein CTD PMID:21080969 ciguatoxin CTX1B affects expression ISO Egfr (Mus musculus) 6480464 Ciguatoxins affects the expression of EGFR mRNA CTD PMID:18353800 cimetidine multiple interactions ISO EGFR (Homo sapiens) 6480464 Cimetidine inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 cimetidine multiple interactions ISO Egfr (Mus musculus) 6480464 [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 Cinobufagin decreases expression ISO EGFR (Homo sapiens) 6480464 cinobufagin results in decreased expression of EGFR protein CTD PMID:34619160 ciprofibrate decreases expression EXP 6480464 ciprofibrate results in decreased expression of EGFR protein CTD PMID:2404574 cisplatin multiple interactions ISO EGFR (Homo sapiens) 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA more ... CTD PMID:15737843 more ... cisplatin multiple interactions ISO Egfr (Mus musculus) 6480464 Cisplatin promotes the reaction [PRKDC protein binds to EGFR protein] CTD PMID:21266349 cisplatin increases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein results in increased susceptibility to Cisplatin CTD PMID:21324906 cisplatin affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Cisplatin CTD PMID:21431282 cisplatin decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR mRNA results in decreased susceptibility to Cisplatin and EGFR results in decreased susceptibility to Cisplatin CTD PMID:18337622 more ... cisplatin increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Cisplatin results in increased phosphorylation of EGFR protein CTD PMID:20726858 clofibrate decreases expression ISO Egfr (Mus musculus) 6480464 Clofibrate results in decreased expression of EGFR mRNA CTD PMID:17585979 clofibrate decreases expression ISO EGFR (Homo sapiens) 6480464 Clofibrate results in decreased expression of EGFR protein CTD PMID:21080969 clofibrate multiple interactions ISO EGFR (Homo sapiens) 6480464 Clofibrate inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of EGFR protein CTD PMID:2404574 clofibrate multiple interactions ISO Egfr (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of EGFR mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of EGFR mRNA] CTD PMID:17585979 cobalt dichloride increases expression ISO EGFR (Homo sapiens) 6480464 cobaltous chloride results in increased expression of EGFR mRNA CTD PMID:19376846 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of EGFR mRNA CTD PMID:24386269 cocaine decreases expression ISO EGFR (Homo sapiens) 6480464 Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 copper atom multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 more ... copper atom decreases expression ISO Egfr (Mus musculus) 6480464 Copper results in decreased expression of EGFR mRNA CTD PMID:17205981 copper(0) multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 more ... copper(0) decreases expression ISO Egfr (Mus musculus) 6480464 Copper results in decreased expression of EGFR mRNA CTD PMID:17205981 copper(II) sulfate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Copper Sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 coumarin affects phosphorylation ISO EGFR (Homo sapiens) 6480464 coumarin affects the phosphorylation of EGFR protein CTD PMID:35688186 crizotinib decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein mutant form results in decreased susceptibility to crizotinib and EGFR protein results in decreased susceptibility to crizotinib CTD PMID:21791641 and PMID:22235099 crizotinib multiple interactions ISO EGFR (Homo sapiens) 6480464 [EGFR protein results in increased phosphorylation of EGFR protein] which results in decreased susceptibility to crizotinib more ... CTD PMID:22277784 and PMID:22553343 crocidolite asbestos increases activity ISO EGFR (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased activity of EGFR protein CTD PMID:21762757 crocidolite asbestos multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Asbestos more ... CTD PMID:10516208 and PMID:26368632 crocidolite asbestos increases expression EXP 6480464 Asbestos more ... CTD PMID:10516208 more ... crocidolite asbestos increases activity ISO Egfr (Mus musculus) 6480464 Asbestos and Crocidolite results in increased activity of EGFR protein CTD PMID:15520183 crocidolite asbestos multiple interactions ISO Egfr (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Asbestos more ... CTD PMID:12154012 and PMID:15520183 crocidolite asbestos increases phosphorylation ISO Egfr (Mus musculus) 6480464 Asbestos and Crocidolite results in increased phosphorylation of EGFR protein CTD PMID:14737115 crocidolite asbestos increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased phosphorylation of EGFR protein CTD PMID:16908449 and PMID:32006662 crocidolite asbestos affects binding ISO EGFR (Homo sapiens) 6480464 Asbestos and Crocidolite binds to EGFR protein CTD PMID:23672436 crocidolite asbestos increases expression ISO EGFR (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of EGFR protein CTD PMID:21570478 crocidolite asbestos multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:15626777 and PMID:16908449 Cryptotanshinone multiple interactions ISO EGFR (Homo sapiens) 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in increased expression of EGFR protein modified form] CTD PMID:30208247 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of EGFR mRNA CTD PMID:26577399 curcumin multiple interactions ISO EGFR (Homo sapiens) 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein] more ... CTD PMID:10851300 more ... curcumin decreases phosphorylation EXP 6480464 Curcumin results in decreased phosphorylation of EGFR protein CTD PMID:17372590 and PMID:18332871 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of EGFR mRNA and Curcumin results in decreased expression of EGFR protein CTD PMID:18332871 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA] CTD PMID:18006644 curcumin decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Curcumin results in decreased phosphorylation of EGFR protein CTD PMID:15486348 and PMID:34994998 curcumin decreases expression ISO EGFR (Homo sapiens) 6480464 Curcumin analog results in decreased expression of EGFR mRNA more ... CTD PMID:15486348 more ... cyanocob(III)alamin multiple interactions ISO Egfr (Mus musculus) 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 cycloheximide increases expression ISO EGFR (Homo sapiens) 6480464 Cycloheximide results in increased expression of EGFR mRNA CTD PMID:15228094 cycloheximide multiple interactions ISO EGFR (Homo sapiens) 6480464 Cycloheximide promotes the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Asbestos and Crocidolite results in increased expression of EGFR protein] CTD PMID:26368632 cyclophosphamide multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 cyclosporin A increases expression ISO EGFR (Homo sapiens) 6480464 Cyclosporine results in increased expression of EGFR mRNA CTD PMID:20106945 cyclosporin A increases phosphorylation ISO Egfr (Mus musculus) 6480464 Cyclosporine results in increased phosphorylation of EGFR protein CTD PMID:32866465 cyclosporin A decreases expression ISO Egfr (Mus musculus) 6480464 Cyclosporine results in decreased expression of EGFR mRNA CTD PMID:19770486 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of EGFR mRNA and cypermethrin results in decreased expression of EGFR protein CTD PMID:22048644 cypermethrin multiple interactions ISO Egfr (Mus musculus) 6480464 [cypermethrin results in decreased susceptibility to Dihydrotestosterone] which results in decreased phosphorylation of EGFR protein CTD PMID:30974244 cypermethrin decreases phosphorylation EXP 6480464 cypermethrin results in decreased phosphorylation of EGFR protein CTD PMID:22048644 cypermethrin affects binding EXP 6480464 cypermethrin binds to EGFR protein CTD PMID:22048644 cytochalasin B multiple interactions ISO EGFR (Homo sapiens) 6480464 Cytochalasin B inhibits the reaction [Asbestos and Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 cytochalasin D multiple interactions ISO EGFR (Homo sapiens) 6480464 Cytochalasin D inhibits the reaction [Asbestos and Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 dacomitinib multiple interactions ISO Egfr (Mus musculus) 6480464 dacomitinib inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:27491023 daidzein multiple interactions ISO EGFR (Homo sapiens) 6480464 [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA more ... CTD PMID:19347870 DDE multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 deguelin decreases expression ISO EGFR (Homo sapiens) 6480464 deguelin metabolite results in decreased expression of EGFR protein and deguelin results in decreased expression of EGFR protein CTD PMID:19139008 dehydroepiandrosterone multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR protein promotes the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA] CTD PMID:25969534 delphinidin decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 delphinidin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 deoxycholic acid increases activity ISO EGFR (Homo sapiens) 6480464 Deoxycholic Acid results in increased activity of EGFR protein CTD PMID:16213893 deoxycholic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 Deoxycholic Acid results in decreased glycosylation of and results in decreased expression of EGFR protein more ... CTD PMID:14747693 and PMID:22223758 deoxycholic acid increases activity EXP 6480464 Deoxycholic Acid results in increased activity of EGFR protein CTD PMID:14747693 deoxycholic acid decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein results in decreased susceptibility to Deoxycholic Acid CTD PMID:12507930 deoxycholic acid increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Deoxycholic Acid results in increased phosphorylation of EGFR protein CTD PMID:14747693 deoxynivalenol decreases expression ISO EGFR (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of EGFR protein CTD PMID:33890134 desferrioxamine B multiple interactions ISO EGFR (Homo sapiens) 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA more ... CTD PMID:15626777 and PMID:35690295 dexamethasone multiple interactions ISO EGFR (Homo sapiens) 6480464 Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]] more ... CTD PMID:10807665 dexamethasone multiple interactions EXP 6480464 Dexamethasone results in decreased phosphorylation of and results in decreased activity of EGFR protein CTD PMID:15556944 Diallyl sulfide decreases expression ISO EGFR (Homo sapiens) 6480464 allyl sulfide results in decreased expression of EGFR protein CTD PMID:34724321 diallyl trisulfide decreases expression ISO EGFR (Homo sapiens) 6480464 diallyl trisulfide results in decreased expression of EGFR protein CTD PMID:23754639 diarsenic trioxide increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of EGFR protein CTD PMID:22532027 diarsenic trioxide decreases expression ISO Egfr (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:23029451 diarsenic trioxide multiple interactions ISO EGFR (Homo sapiens) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15961274 more ... diarsenic trioxide affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Arsenic Trioxide and EGFR protein mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:29535630 and PMID:30237564 diarsenic trioxide decreases expression ISO EGFR (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of EGFR mRNA and Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:20435036 more ... diarsenic trioxide multiple interactions ISO Egfr (Mus musculus) 6480464 [Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein CTD PMID:21434348 diarsenic trioxide increases expression ISO EGFR (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of EGFR mRNA CTD PMID:22521957 and PMID:29274334 diazinon affects expression EXP 6480464 Diazinon affects the expression of EGFR mRNA CTD PMID:22546817 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:16391241 dibenziodolium multiple interactions ISO EGFR (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 dibutyl phthalate multiple interactions ISO EGFR (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 dibutyl phthalate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Dibutyl Phthalate results in increased phosphorylation of EGFR protein CTD PMID:22552774 diclofenac increases expression ISO Egfr (Mus musculus) 6480464 Diclofenac results in increased expression of EGFR mRNA CTD PMID:26934552 dicrotophos increases expression ISO EGFR (Homo sapiens) 6480464 dicrotophos results in increased expression of EGFR mRNA CTD PMID:28302478 Didecyldimethylammonium decreases expression ISO EGFR (Homo sapiens) 6480464 didecyldimethylammonium results in decreased expression of EGFR protein CTD PMID:32763356 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of EGFR mRNA CTD PMID:22546817 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of EGFR mRNA CTD PMID:17011747 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of EGFR mRNA CTD PMID:16122865 dioxygen multiple interactions ISO EGFR (Homo sapiens) 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of EGFR mRNA more ... CTD PMID:21300668 and PMID:32992648 disodium selenite decreases expression ISO Egfr (Mus musculus) 6480464 Sodium Selenite results in decreased expression of EGFR mRNA CTD PMID:23274088 dobutamine decreases response to substance ISO Egfr (Mus musculus) 6480464 EGFR gene mutant form results in decreased susceptibility to Dobutamine CTD PMID:18599591 dobutamine multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 dorsomorphin multiple interactions ISO EGFR (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of EGFR protein CTD PMID:17974986 doxorubicin affects expression ISO EGFR (Homo sapiens) 6480464 Doxorubicin affects the expression of EGFR protein CTD PMID:35218280 doxorubicin decreases expression ISO EGFR (Homo sapiens) 6480464 Doxorubicin results in decreased expression of EGFR mRNA CTD PMID:29803840 doxorubicin increases expression ISO EGFR (Homo sapiens) 6480464 Doxorubicin results in increased expression of EGFR mRNA CTD PMID:30031762 doxorubicin increases expression ISO Egfr (Mus musculus) 6480464 Doxorubicin results in increased expression of EGFR mRNA CTD PMID:25896364 doxorubicin increases phosphorylation ISO Egfr (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of EGFR protein CTD PMID:17974986 doxorubicin multiple interactions EXP 6480464 Doxorubicin results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:15843167 doxorubicin multiple interactions ISO EGFR (Homo sapiens) 6480464 [[Gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin more ... CTD PMID:15981280 more ... elemental selenium decreases expression ISO EGFR (Homo sapiens) 6480464 Selenium results in decreased expression of EGFR mRNA CTD PMID:17390030 epoxiconazole multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 epoxiconazole decreases expression ISO Egfr (Mus musculus) 6480464 epoxiconazole results in decreased expression of EGFR mRNA CTD PMID:35436446 equol multiple interactions ISO EGFR (Homo sapiens) 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased chemical synthesis of Oxygen] more ... CTD PMID:21300668 Erionite increases expression EXP 6480464 erionite results in increased expression of EGFR protein CTD PMID:26368632 erlotinib hydrochloride multiple interactions ISO EGFR (Homo sapiens) 6480464 [Erlotinib Hydrochloride results in decreased activity of EGFR protein] which results in decreased expression of RAD50 protein more ... CTD PMID:19168569 more ... erlotinib hydrochloride decreases expression ISO EGFR (Homo sapiens) 6480464 Erlotinib Hydrochloride results in decreased expression of EGFR protein modified form CTD PMID:30136359 erlotinib hydrochloride decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein mutant form results in decreased susceptibility to Erlotinib Hydrochloride CTD PMID:16407879 erlotinib hydrochloride decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of EGFR protein CTD PMID:16891461 more ... erlotinib hydrochloride decreases activity ISO EGFR (Homo sapiens) 6480464 Erlotinib Hydrochloride results in decreased activity of EGFR protein CTD PMID:12907618 more ... erlotinib hydrochloride affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Erlotinib Hydrochloride and EGFR protein mutant form affects the susceptibility to Erlotinib Hydrochloride CTD PMID:21080748 estrone multiple interactions ISO Egfr (Mus musculus) 6480464 Estrone inhibits the reaction [LEPR gene mutant form inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein]] and Estrone inhibits the reaction [LEPR gene mutant form results in decreased expression of EGFR mRNA] CTD PMID:1753381 ethanol increases expression EXP 6480464 Ethanol results in increased expression of EGFR mRNA CTD PMID:15353170 ethanol increases expression ISO Egfr (Mus musculus) 6480464 Ethanol results in increased expression of EGFR mRNA CTD PMID:30319688 ethanol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Ethanol co-treated with CYP2E1 protein] results in increased phosphorylation of EGFR protein CTD PMID:22222162 ethanol decreases expression ISO Egfr (Mus musculus) 6480464 Ethanol results in decreased expression of EGFR mRNA CTD PMID:19167417 etoposide decreases expression ISO EGFR (Homo sapiens) 6480464 Etoposide results in decreased expression of EGFR mRNA and Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 eugenol decreases expression ISO Egfr (Mus musculus) 6480464 Eugenol results in decreased expression of EGFR protein CTD PMID:15618236 eugenol increases expression ISO Egfr (Mus musculus) 6480464 Eugenol results in increased expression of EGFR mRNA CTD PMID:15618236 everolimus increases expression ISO EGFR (Homo sapiens) 6480464 Everolimus results in increased expression of EGFR mRNA and Everolimus results in increased expression of EGFR protein CTD PMID:28711525 everolimus multiple interactions ISO EGFR (Homo sapiens) 6480464 platycodin D inhibits the reaction [Everolimus results in increased expression of EGFR protein] CTD PMID:28711525 Evodiamine multiple interactions ISO Egfr (Mus musculus) 6480464 EGFR mutant form inhibits the reaction [evodiamine results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:19854188 Evodiamine increases phosphorylation ISO Egfr (Mus musculus) 6480464 evodiamine results in increased phosphorylation of EGFR protein CTD PMID:19854188 fenamidone increases expression ISO Egfr (Mus musculus) 6480464 fenamidone results in increased expression of EGFR mRNA CTD PMID:27029645 fenofibrate decreases expression ISO Egfr (Mus musculus) 6480464 Fenofibrate results in decreased expression of EGFR mRNA CTD PMID:11798191 ferric oxide increases phosphorylation ISO Egfr (Mus musculus) 6480464 ferric oxide analog results in increased phosphorylation of EGFR protein CTD PMID:24068039 fisetin multiple interactions ISO EGFR (Homo sapiens) 6480464 fisetin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of EGFR protein modified form] CTD PMID:31606474 fluoranthene multiple interactions ISO Egfr (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of EGFR mRNA CTD PMID:28329830 fluoxetine increases phosphorylation ISO Egfr (Mus musculus) 6480464 Fluoxetine results in increased phosphorylation of EGFR protein CTD PMID:18758753 fluoxetine multiple interactions ISO Egfr (Mus musculus) 6480464 [[Fluoxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:18758753 and PMID:19662385 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of EGFR mRNA CTD PMID:24136188 folic acid multiple interactions ISO Egfr (Mus musculus) 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA more ... CTD PMID:23255615 and PMID:33549593 folic acid decreases expression ISO Egfr (Mus musculus) 6480464 Folic Acid results in decreased expression of EGFR mRNA CTD PMID:25629700 formononetin decreases phosphorylation ISO EGFR (Homo sapiens) 151357000 formononetin decreases phosphorylation of EGFR protein in lung RGD fulvestrant multiple interactions ISO EGFR (Homo sapiens) 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of EGFR gene more ... CTD PMID:22552774 more ... furan decreases expression EXP 6480464 furan results in decreased expression of EGFR mRNA CTD PMID:25539665 galangin multiple interactions ISO EGFR (Homo sapiens) 6480464 galangin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 galaxolide increases expression ISO EGFR (Homo sapiens) 6480464 galaxolide results in increased expression of EGFR mRNA CTD PMID:34687775 galaxolide multiple interactions ISO EGFR (Homo sapiens) 6480464 [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of EGFR mRNA CTD PMID:34687775 gallic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:27087131 and PMID:27634460 gedunin decreases expression ISO EGFR (Homo sapiens) 6480464 gedunin results in decreased expression of EGFR protein CTD PMID:17010675 gefitinib decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene mutant form results in decreased susceptibility to Gefitinib and EGFR protein mutant form results in decreased susceptibility to Gefitinib CTD PMID:16740687 more ... gefitinib decreases activity EXP 6480464 Gefitinib results in decreased activity of EGFR protein CTD PMID:29228391 and PMID:32370496 gefitinib multiple interactions EXP 6480464 gefitinib inhibits the reaction [HBEGF protein inhibits the reaction [sodium arsenite results in decreased phosphorylation of and results in decreased activity of EGFR protein]] CTD PMID:29228391 gefitinib decreases activity ISO EGFR (Homo sapiens) 6480464 Gefitinib results in decreased activity of EGFR protein CTD PMID:17938326 more ... gefitinib decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Gefitinib results in decreased phosphorylation of EGFR protein CTD PMID:13680161 more ... gefitinib decreases phosphorylation EXP 6480464 gefitinib results in decreased phosphorylation of EGFR protein CTD PMID:18375820 gefitinib decreases expression EXP 6480464 gefitinib results in decreased expression of EGFR protein modified form CTD PMID:15660382 gefitinib multiple interactions ISO Egfr (Mus musculus) 6480464 [Gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene more ... CTD PMID:15841081 more ... gefitinib decreases expression ISO EGFR (Homo sapiens) 6480464 Gefitinib results in decreased expression of EGFR protein modified form CTD PMID:19288272 and PMID:30136359 gefitinib multiple interactions ISO EGFR (Homo sapiens) 6480464 [[Gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin more ... CTD PMID:13680161 more ... gefitinib increases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene mutant form results in increased susceptibility to gefitinib more ... CTD PMID:16115929 more ... gefitinib affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene mutant form affects the susceptibility to Gefitinib more ... CTD PMID:15976335 more ... geldanamycin multiple interactions ISO EGFR (Homo sapiens) 6480464 geldanamycin promotes the reaction [Sulfasalazine results in decreased expression of EGFR protein] CTD PMID:20007406 geldanamycin multiple interactions EXP 6480464 geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9605431 geldanamycin multiple interactions ISO Egfr (Mus musculus) 6480464 geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9664232 geldanamycin decreases expression ISO EGFR (Homo sapiens) 6480464 geldanamycin results in decreased expression of EGFR protein CTD PMID:20007406 gemcitabine multiple interactions ISO EGFR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein] more ... CTD PMID:17146438 more ... gemcitabine decreases expression ISO EGFR (Homo sapiens) 6480464 Gemcitabine results in decreased expression of EGFR mRNA and Gemcitabine results in decreased expression of EGFR protein CTD PMID:17146438 and PMID:20103597 gemcitabine increases degradation ISO EGFR (Homo sapiens) 6480464 Gemcitabine results in increased degradation of EGFR protein CTD PMID:17146438 gemcitabine increases expression ISO EGFR (Homo sapiens) 6480464 Gemcitabine results in increased expression of EGFR mRNA CTD PMID:17146438 gemcitabine increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Gemcitabine results in increased phosphorylation of EGFR protein CTD PMID:17146438 and PMID:20726858 genistein multiple interactions ISO EGFR (Homo sapiens) 6480464 [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA more ... CTD PMID:19347870 genistein multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Genistein results in increased secretion of Testosterone] CTD PMID:19059320 genistein increases expression EXP 6480464 Genistein results in increased expression of EGFR protein CTD PMID:15781664 genistein decreases expression ISO Egfr (Mus musculus) 6480464 Genistein results in decreased expression of EGFR mRNA CTD PMID:11880592 genistein decreases expression ISO EGFR (Homo sapiens) 6480464 Genistein results in decreased expression of EGFR mRNA CTD PMID:15257099 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of EGFR mRNA CTD PMID:22061828 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of EGFR mRNA CTD PMID:24136188 glutathione multiple interactions ISO EGFR (Homo sapiens) 6480464 Glutathione inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein] CTD PMID:14660655 glutathione multiple interactions ISO Egfr (Mus musculus) 6480464 [Acetaminophen results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein and [phorone results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 glycine betaine multiple interactions ISO Egfr (Mus musculus) 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 glyphosate decreases expression ISO EGFR (Homo sapiens) 6480464 glyphosate results in decreased expression of EGFR mRNA CTD PMID:31295307 Goe 6976 multiple interactions ISO EGFR (Homo sapiens) 6480464 Go 6976 inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein] and Go 6976 inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein] CTD PMID:15723263 Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [EGF protein binds to and results in increased localization of EGFR protein] CTD PMID:11134345 gold atom multiple interactions ISO EGFR (Homo sapiens) 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 gold(0) multiple interactions ISO EGFR (Homo sapiens) 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 helioxanthin multiple interactions ISO Egfr (Mus musculus) 6480464 [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the localization of EGFR protein modified form and helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased phosphorylation of EGFR protein] CTD PMID:26464283 heparin decreases expression ISO EGFR (Homo sapiens) 6480464 Heparin results in decreased expression of EGFR mRNA and Heparin results in decreased expression of EGFR protein CTD PMID:16475731 heparin increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Heparin results in increased phosphorylation of EGFR protein CTD PMID:16556679 herbicide decreases expression EXP 6480464 Herbicides results in decreased expression of EGFR mRNA CTD PMID:32360609 hexachlorobenzene multiple interactions ISO EGFR (Homo sapiens) 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein] more ... CTD PMID:21205633 and PMID:23462309 hexachlorobenzene increases expression ISO Egfr (Mus musculus) 6480464 Hexachlorobenzene results in increased expression of EGFR mRNA CTD PMID:28923513 hexachlorobenzene multiple interactions ISO Egfr (Mus musculus) 6480464 Hexachlorobenzene affects the reaction [AHR protein affects the expression of EGFR mRNA] CTD PMID:28923513 hexachlorobenzene multiple interactions EXP 6480464 AG 1879 inhibits the reaction [SRC protein promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]] more ... CTD PMID:18295415 and PMID:22245120 hexachlorobenzene increases phosphorylation EXP 6480464 Hexachlorobenzene results in increased phosphorylation of EGFR protein CTD PMID:18295415 hexachlorobenzene increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Hexachlorobenzene results in increased phosphorylation of EGFR protein CTD PMID:21205633 hexadecanoic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 histamine multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the reaction [Histamine results in increased secretion of MMP1 protein] CTD PMID:17656145 hyaluronic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 hydrogen chloride multiple interactions EXP 6480464 Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] more ... CTD PMID:15309881 hydrogen chloride increases expression EXP 6480464 Hydrochloric Acid results in increased expression of EGFR protein CTD PMID:15309881 hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of EGFR protein CTD PMID:19885844 hydrogen peroxide affects expression ISO EGFR (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of EGFR protein CTD PMID:21179406 hydrogen peroxide multiple interactions ISO EGFR (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:10640773 more ... hydrogen peroxide multiple interactions ISO Egfr (Mus musculus) 6480464 AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EGFR protein] CTD PMID:14737115 hydrogen peroxide increases phosphorylation ISO Egfr (Mus musculus) 6480464 Hydrogen Peroxide results in increased phosphorylation of EGFR protein CTD PMID:14737115 hydroxamic acid multiple interactions ISO Egfr (Mus musculus) 6480464 Hydroxamic Acids analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] CTD PMID:26088127 hyperforin decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 hyperforin results in decreased phosphorylation of EGFR protein CTD PMID:32485087 hypochlorous acid multiple interactions ISO EGFR (Homo sapiens) 6480464 Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:18156441 icariin multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein and [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 icariside II multiple interactions ISO EGFR (Homo sapiens) 6480464 baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25119583 icariside II decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 baohuoside I results in decreased phosphorylation of EGFR protein CTD PMID:25119583 ICI-164384 multiple interactions ISO EGFR (Homo sapiens) 6480464 ICI 164384 inhibits the reaction [[Estradiol co-treated with EGFR protein] results in increased expression of SIAH2 mRNA] CTD PMID:18629630 indole-3-methanol decreases expression ISO EGFR (Homo sapiens) 6480464 indole-3-carbinol results in decreased expression of EGFR protein CTD PMID:18025290 indometacin increases expression ISO Egfr (Mus musculus) 6480464 Indomethacin results in increased expression of EGFR protein CTD PMID:17977527 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of EGFR mRNA CTD PMID:29523851 indometacin multiple interactions EXP 6480464 Irbesartan inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] and Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 indometacin multiple interactions ISO Egfr (Mus musculus) 6480464 malabaricone B promotes the reaction [Indomethacin results in increased expression of EGFR protein] and malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 inulin multiple interactions ISO Egfr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of EGFR mRNA CTD PMID:36331819 irbesartan multiple interactions EXP 6480464 Irbesartan inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 irinotecan multiple interactions ISO EGFR (Homo sapiens) 6480464 bisindolylmaleimide I inhibits the reaction [Irinotecan metabolite results in increased phosphorylation of EGFR protein] more ... CTD PMID:15723263 iron atom multiple interactions ISO EGFR (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 iron(0) multiple interactions ISO EGFR (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 isoflavones multiple interactions EXP 6480464 Isoflavones inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of EGFR mRNA] CTD PMID:34197824 isoprenaline increases expression ISO Egfr (Mus musculus) 6480464 Isoproterenol results in increased expression of EGFR mRNA CTD PMID:20003209 isoprenaline multiple interactions ISO EGFR (Homo sapiens) 6480464 Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein] CTD PMID:18787115 isotretinoin decreases expression ISO EGFR (Homo sapiens) 6480464 Isotretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 ivermectin decreases expression ISO EGFR (Homo sapiens) 6480464 Ivermectin results in decreased expression of EGFR protein CTD PMID:32959892 JTE-013 multiple interactions ISO EGFR (Homo sapiens) 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of EGFR protein] and JTE 013 inhibits the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:26518876 ketoconazole multiple interactions ISO EGFR (Homo sapiens) 6480464 Ketoconazole inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of EGFR mRNA CTD PMID:37077353 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 KN-93 multiple interactions ISO EGFR (Homo sapiens) 6480464 KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein] CTD PMID:32535744 L-ascorbic acid decreases expression ISO EGFR (Homo sapiens) 6480464 Ascorbic Acid results in decreased expression of EGFR mRNA CTD PMID:21919647 L-methionine multiple interactions ISO Egfr (Mus musculus) 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 lansoprazole increases expression ISO EGFR (Homo sapiens) 6480464 Lansoprazole results in increased expression of EGFR protein CTD PMID:9881512 lapatinib decreases activity ISO EGFR (Homo sapiens) 6480464 lapatinib results in decreased activity of EGFR protein CTD PMID:15665275 more ... lapatinib multiple interactions ISO EGFR (Homo sapiens) 6480464 KRAS protein affects the reaction [EGFR protein affects the susceptibility to lapatinib] more ... CTD PMID:28739874 lapatinib affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to lapatinib CTD PMID:28739874 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of EGFR protein CTD PMID:17298174 lead diacetate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 lead acetate results in increased phosphorylation of EGFR protein CTD PMID:19133285 lead diacetate multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:19133285 lead nitrate multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone] more ... CTD PMID:20850495 lead nitrate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 lead nitrate results in increased phosphorylation of EGFR protein CTD PMID:20850495 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of EGFR protein CTD PMID:17298174 leflunomide increases expression ISO EGFR (Homo sapiens) 6480464 leflunomide results in increased expression of EGFR mRNA CTD PMID:28988120 leflunomide multiple interactions ISO EGFR (Homo sapiens) 6480464 Leflunomide inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:30364229 leukotriene C4 increases expression ISO Egfr (Mus musculus) 6480464 Leukotriene C4 results in increased expression of EGFR mRNA CTD PMID:12388339 linalool increases expression ISO EGFR (Homo sapiens) 6480464 linalool results in increased expression of EGFR mRNA CTD PMID:19922762 linuron multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 linuron decreases expression EXP 6480464 Linuron results in decreased expression of EGFR mRNA CTD PMID:12730624 lipopolysaccharide increases phosphorylation ISO Egfr (Mus musculus) 6480464 Lipopolysaccharides results in increased phosphorylation of EGFR protein CTD PMID:21874253 and PMID:23099361 lipopolysaccharide multiple interactions ISO EGFR (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 lipopolysaccharide multiple interactions ISO Egfr (Mus musculus) 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] and TLR4 mutant form promotes the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] CTD PMID:21874253 and PMID:23099361 lithium chloride increases expression ISO EGFR (Homo sapiens) 6480464 Lithium Chloride results in increased expression of EGFR mRNA and Lithium Chloride results in increased expression of EGFR protein CTD PMID:22493441 lithium chloride multiple interactions ISO EGFR (Homo sapiens) 6480464 [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA more ... CTD PMID:22493441 lovastatin multiple interactions ISO EGFR (Homo sapiens) 6480464 Lovastatin inhibits the reaction [EGF protein promotes the reaction [EGFR protein results in increased phosphorylation of EGFR protein]] and Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:12942316 and PMID:19760159 luteolin multiple interactions ISO EGFR (Homo sapiens) 6480464 EGF protein inhibits the reaction [Luteolin results in decreased phosphorylation of EGFR protein] more ... CTD PMID:10556937 more ... luteolin decreases expression ISO EGFR (Homo sapiens) 6480464 Luteolin results in decreased expression of EGFR mRNA CTD PMID:22926442 luteolin affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Luteolin CTD PMID:12168845 LY294002 multiple interactions ISO EGFR (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 Maduramicin multiple interactions EXP 6480464 maduramicin affects the reaction [EGF protein affects the degradation of EGFR protein] and maduramicin affects the reaction [EGF protein affects the phosphorylation of EGFR protein] CTD PMID:37394175 magnesium dichloride multiple interactions ISO EGFR (Homo sapiens) 6480464 [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 Malabaricone C multiple interactions ISO Egfr (Mus musculus) 6480464 malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 manganese(II) chloride increases activity ISO EGFR (Homo sapiens) 6480464 manganese chloride results in increased activity of EGFR protein CTD PMID:2354210 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of EGFR mRNA CTD PMID:28801915 manganese(II) chloride multiple interactions ISO EGFR (Homo sapiens) 6480464 [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 melittin increases activity ISO EGFR (Homo sapiens) 6480464 Melitten results in increased activity of EGFR protein CTD PMID:22613720 menadione increases phosphorylation EXP 6480464 Vitamin K 3 results in increased phosphorylation of EGFR protein CTD PMID:15843167 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of EGFR mRNA CTD PMID:10901180 mercury dichloride increases expression ISO EGFR (Homo sapiens) 6480464 Mercuric Chloride results in increased expression of EGFR mRNA CTD PMID:37172713 metamizole sodium multiple interactions EXP 6480464 Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of EGFR mRNA CTD PMID:30467583 methidathion increases expression ISO Egfr (Mus musculus) 6480464 methidathion results in increased expression of EGFR mRNA CTD PMID:34813904 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of EGFR mRNA CTD PMID:30047161 methotrexate decreases response to substance ISO Egfr (Mus musculus) 6480464 EGFR mRNA results in decreased susceptibility to Methotrexate CTD PMID:16918715 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of EGFR mRNA CTD PMID:18803016 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of EGFR protein CTD PMID:8888411 methoxychlor increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Methoxychlor results in increased phosphorylation of EGFR protein CTD PMID:28426875 methoxychlor multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 Methylazoxymethanol acetate increases expression EXP 6480464 Methylazoxymethanol Acetate results in increased expression of EGFR mRNA CTD PMID:28349193 methylmercury chloride increases phosphorylation ISO EGFR (Homo sapiens) 6480464 methylmercuric chloride results in increased phosphorylation of EGFR protein CTD PMID:28958600 methylmercury chloride increases expression ISO EGFR (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of EGFR mRNA CTD PMID:28001369 mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]] CTD PMID:20359552 microcystin-LR decreases methylation ISO EGFR (Homo sapiens) 6480464 cyanoginosin LR results in decreased methylation of EGFR gene CTD PMID:29518473 microcystin-LR increases expression ISO EGFR (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of EGFR mRNA CTD PMID:29518473 mifepristone multiple interactions ISO EGFR (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]]] more ... CTD PMID:10807665 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of EGFR mRNA CTD PMID:18591650 and PMID:25972201 MK-2206 increases expression ISO EGFR (Homo sapiens) 6480464 MK 2206 results in increased expression of EGFR protein CTD PMID:27897231 MK-2206 multiple interactions ISO EGFR (Homo sapiens) 6480464 platycodin D inhibits the reaction [MK 2206 results in increased expression of EGFR protein] CTD PMID:27897231 monosodium L-glutamate multiple interactions ISO Egfr (Mus musculus) 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of EGFR mRNA CTD PMID:19001666 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of EGFR mRNA CTD PMID:28954212 myo-inositol hexakisphosphate multiple interactions ISO EGFR (Homo sapiens) 6480464 Phytic Acid inhibits the reaction [Asbestos and Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 myricetin multiple interactions ISO Egfr (Mus musculus) 6480464 myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18995957 myricetin decreases phosphorylation ISO Egfr (Mus musculus) 6480464 myricetin results in decreased phosphorylation of EGFR protein CTD PMID:18995957 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO EGFR (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA] CTD PMID:22493441 N-acetyl-L-cysteine multiple interactions ISO Egfr (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:15520183 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:15849355 more ... N-acetyl-L-cysteine multiple interactions ISO EGFR (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein] more ... CTD PMID:10640773 more ... N-acetylcysteamine decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 2-acetamidoethanethiol analog results in decreased phosphorylation of EGFR protein CTD PMID:20058253 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO EGFR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein] more ... CTD PMID:17146438 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO EGFR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGFR protein CTD PMID:20332299 N-ethyl-N-nitrosourea increases mutagenesis ISO Egfr (Mus musculus) 6480464 Ethylnitrosourea results in increased mutagenesis of EGFR gene CTD PMID:15366372 and PMID:16724327 N-methyl-N'-nitro-N-nitrosoguanidine affects localization ISO EGFR (Homo sapiens) 6480464 Methylnitronitrosoguanidine affects the localization of EGFR protein CTD PMID:15708576 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO EGFR (Homo sapiens) 6480464 Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:15708576 N-methyl-N-nitrosourea multiple interactions EXP 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein more ... CTD PMID:22245120 and PMID:25164625 N-methylformamide decreases expression ISO Egfr (Mus musculus) 6480464 methylformamide analog results in decreased expression of EGFR mRNA and methylformamide results in decreased expression of EGFR mRNA CTD PMID:17040096 N-methylnicotinate multiple interactions ISO EGFR (Homo sapiens) 6480464 trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:33148531 N-methylnicotinate decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 trigonelline results in decreased phosphorylation of EGFR protein CTD PMID:33148531 N-nitrosodiethylamine multiple interactions ISO Egfr (Mus musculus) 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA more ... CTD PMID:17942915 more ... N-nitrosodiethylamine increases expression ISO Egfr (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of EGFR mRNA CTD PMID:27058323 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of EGFR mRNA and Diethylnitrosamine results in decreased expression of EGFR protein CTD PMID:15660382 and PMID:19638242 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein more ... CTD PMID:28943392 more ... N-nitrosodiethylamine decreases expression ISO Egfr (Mus musculus) 6480464 Diethylnitrosamine results in decreased expression of EGFR protein CTD PMID:20583210 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 naphthalene multiple interactions ISO Egfr (Mus musculus) 6480464 [gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene CTD PMID:20935109 naringin multiple interactions ISO EGFR (Homo sapiens) 6480464 naringin inhibits the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:22766066 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of EGFR mRNA CTD PMID:24136188 neocuproine multiple interactions ISO EGFR (Homo sapiens) 6480464 [Copper binds to neocuproine] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 neratinib decreases activity ISO EGFR (Homo sapiens) 6480464 neratinib results in decreased activity of EGFR protein and neratinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 and PMID:22242139 nevirapine decreases expression ISO EGFR (Homo sapiens) 6480464 Nevirapine results in decreased expression of EGFR mRNA CTD PMID:19152342 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of EGFR mRNA CTD PMID:22546817 nickel dichloride increases expression ISO EGFR (Homo sapiens) 6480464 nickel chloride results in increased expression of EGFR protein CTD PMID:26026961 nickel dichloride multiple interactions ISO EGFR (Homo sapiens) 6480464 RECK protein inhibits the reaction [nickel chloride results in increased expression of EGFR protein] CTD PMID:26026961 nickel subsulfide increases expression EXP 6480464 nickel subsulfide results in increased expression of EGFR mRNA CTD PMID:21086188 nickel sulfate multiple interactions ISO Egfr (Mus musculus) 6480464 [TGFA protein binds to and affects the activity of EGFR protein] which results in decreased susceptibility to nickel sulfate CTD PMID:19131640 niclosamide decreases expression ISO EGFR (Homo sapiens) 6480464 Niclosamide analog results in decreased expression of EGFR protein more ... CTD PMID:28284560 and PMID:30779072 niclosamide decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Niclosamide results in decreased phosphorylation of EGFR protein CTD PMID:28426875 nicotine increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of EGFR protein CTD PMID:14569062 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of EGFR mRNA CTD PMID:11478936 nicotine multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Nicotine results in increased phosphorylation of EGFR protein] CTD PMID:14569062 nobiletin multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein and [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 O-methyleugenol decreases expression ISO Egfr (Mus musculus) 6480464 methyleugenol results in decreased expression of EGFR protein CTD PMID:15618236 ochratoxin A increases phosphorylation ISO Egfr (Mus musculus) 6480464 ochratoxin A results in increased phosphorylation of EGFR protein CTD PMID:23172667 oleic acid increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Oleic Acid results in increased phosphorylation of EGFR protein CTD PMID:27447558 oleic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 omipalisib multiple interactions ISO EGFR (Homo sapiens) 6480464 omipalisib inhibits the reaction [RHPN1-AS1 protein results in increased expression of EGFR protein] CTD PMID:36125241 oridonin multiple interactions ISO EGFR (Homo sapiens) 6480464 oridonin analog inhibits the reaction [EGF protein promotes the reaction [EGFR protein modified form binds to STAT3 protein]] and oridonin analog inhibits the reaction [EGFR protein results in increased phosphorylation of STAT3 protein] CTD PMID:31594861 osimertinib multiple interactions ISO EGFR (Homo sapiens) 6480464 osimertinib affects the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:30145802 more ... osimertinib decreases phosphorylation ISO EGFR (Homo sapiens) 151357000 osimertinib decreases phosphorylation of EGFR protein in lung RGD osimertinib decreases phosphorylation ISO Egfr (Mus musculus) 6480464 osimertinib results in decreased phosphorylation of EGFR protein CTD PMID:35970427 osimertinib decreases activity ISO EGFR (Homo sapiens) 6480464 osimertinib results in decreased activity of EGFR protein CTD PMID:28237877 ouabain decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Ouabain results in decreased phosphorylation of EGFR protein CTD PMID:28795476 oxaliplatin multiple interactions ISO EGFR (Homo sapiens) 6480464 [gefitinib co-treated with oxaliplatin] results in decreased phosphorylation of EGFR protein and EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] CTD PMID:13680161 and PMID:16098254 oxaliplatin increases phosphorylation ISO EGFR (Homo sapiens) 6480464 oxaliplatin results in increased phosphorylation of EGFR protein CTD PMID:16243822 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EGFR mRNA CTD PMID:25729387 oxazepam decreases expression ISO Egfr (Mus musculus) 6480464 Oxazepam results in decreased expression of EGFR mRNA and Oxazepam results in decreased expression of EGFR protein CTD PMID:15618236 oxytocin increases expression EXP 6480464 Oxytocin results in increased expression of EGFR protein modified form CTD PMID:23707249 ozone multiple interactions ISO EGFR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of EGFR mRNA more ... CTD PMID:19536146 more ... ozone increases phosphorylation ISO Egfr (Mus musculus) 6480464 Ozone results in increased phosphorylation of EGFR protein CTD PMID:26464147 ozone multiple interactions ISO Egfr (Mus musculus) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:26464147 and PMID:34911549 ozone increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Ozone results in increased phosphorylation of EGFR protein CTD PMID:19536146 and PMID:25303742 p-chloromercuribenzoic acid decreases expression ISO EGFR (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of EGFR mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EGFR mRNA CTD PMID:27188386 p-tert-Amylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 p-tert-Amylphenol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of EGFR protein CTD PMID:32466334 paclitaxel increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Paclitaxel results in increased phosphorylation of EGFR protein CTD PMID:16211241 and PMID:20726858 paclitaxel decreases expression ISO EGFR (Homo sapiens) 6480464 Paclitaxel results in decreased expression of EGFR mRNA CTD PMID:18058816 paclitaxel multiple interactions ISO EGFR (Homo sapiens) 6480464 [PD168393 co-treated with Paclitaxel] results in decreased phosphorylation of EGFR protein and Paclitaxel promotes the reaction [HER3 protein binds to EGFR protein] CTD PMID:16413505 and PMID:20726858 Paeonol multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein and [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 pamidronate multiple interactions ISO EGFR (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Pamidronate] promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] and Pamidronate promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:32337366 paracetamol multiple interactions ISO Egfr (Mus musculus) 6480464 [Acetaminophen results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein more ... CTD PMID:17585979 and PMID:28123000 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EGFR mRNA CTD PMID:33387578 paracetamol increases expression ISO EGFR (Homo sapiens) 6480464 Acetaminophen results in increased expression of EGFR mRNA CTD PMID:29067470 paracetamol multiple interactions ISO EGFR (Homo sapiens) 6480464 Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 paracetamol affects localization ISO Egfr (Mus musculus) 6480464 Acetaminophen affects the localization of EGFR protein CTD PMID:28123000 paracetamol decreases expression ISO EGFR (Homo sapiens) 6480464 Acetaminophen results in decreased expression of EGFR mRNA CTD PMID:21420995 paracetamol decreases expression ISO Egfr (Mus musculus) 6480464 Acetaminophen results in decreased expression of EGFR mRNA and Acetaminophen results in decreased expression of EGFR protein CTD PMID:15618236 and PMID:24126418 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of EGFR protein CTD PMID:17298174 parathion multiple interactions ISO EGFR (Homo sapiens) 6480464 [Parathion co-treated with Estradiol] results in increased expression of EGFR protein and Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 and PMID:17622325 parathion increases expression ISO EGFR (Homo sapiens) 6480464 Parathion results in increased expression of EGFR protein CTD PMID:17390078 and PMID:17622325 paroxetine multiple interactions ISO Egfr (Mus musculus) 6480464 [[Paroxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:19662385 PD 168393 multiple interactions ISO EGFR (Homo sapiens) 6480464 [PD168393 co-treated with Paclitaxel] results in decreased phosphorylation of EGFR protein more ... CTD PMID:16413505 more ... PD 168393 multiple interactions EXP 6480464 PD168393 inhibits the reaction [AGT protein results in increased phosphorylation of EGFR protein] CTD PMID:25398788 PD 168393 affects localization ISO EGFR (Homo sapiens) 6480464 PD168393 affects the localization of EGFR protein and PD168393 affects the localization of EGFR protein modified form CTD PMID:21967610 PD 168393 decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 PD168393 results in decreased phosphorylation of EGFR protein CTD PMID:21967610 and PMID:23527233 pentane-2,3-dione increases expression EXP 6480464 2 and 3-pentanedione results in increased expression of EGFR mRNA CTD PMID:25710175 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of EGFR mRNA and perfluorooctane sulfonic acid results in increased expression of EGFR protein CTD PMID:21251948 perfluorooctane-1-sulfonic acid multiple interactions ISO Egfr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EGFR mRNA more ... CTD PMID:36331819 perfluorooctane-1-sulfonic acid increases phosphorylation ISO Egfr (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of EGFR protein CTD PMID:28288859 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of EGFR mRNA CTD PMID:16221955 perfluorooctanoic acid decreases expression ISO Egfr (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of EGFR protein CTD PMID:22414604 perfluorooctanoic acid multiple interactions ISO Egfr (Mus musculus) 6480464 Estradiol inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein] more ... CTD PMID:22414604 perfluorooctanoic acid increases expression ISO Egfr (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of EGFR protein CTD PMID:20118188 PHA-665752 decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 5-((2 more ... CTD PMID:21266357 PHA-665752 multiple interactions ISO EGFR (Homo sapiens) 6480464 [5-((2 more ... CTD PMID:21266357 phenobarbital multiple interactions ISO Egfr (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of EGFR mRNA] and Phenobarbital inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:19482888 and PMID:6309801 phenobarbital multiple interactions ISO EGFR (Homo sapiens) 6480464 Phenobarbital inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 and PMID:30364229 phenobarbital affects expression ISO Egfr (Mus musculus) 6480464 Phenobarbital affects the expression of EGFR mRNA CTD PMID:19136022 and PMID:23091169 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of EGFR mRNA CTD PMID:19162173 phenobarbital decreases expression ISO Egfr (Mus musculus) 6480464 Phenobarbital results in decreased expression of EGFR mRNA CTD PMID:19482888 phenobarbital multiple interactions EXP 6480464 Phenobarbital inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:10828207 phenylarsine oxide multiple interactions ISO Egfr (Mus musculus) 6480464 oxophenylarsine inhibits the reaction [EGF protein binds to and affects the localization of EGFR protein] CTD PMID:12093727 phenylephrine multiple interactions ISO Egfr (Mus musculus) 6480464 Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] and Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:18360054 phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of EGFR protein CTD PMID:14676212 phenylephrine multiple interactions EXP 6480464 [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein] and [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein] CTD PMID:16760267 phenylmercury acetate increases expression ISO EGFR (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of EGFR mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO EGFR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of EGFR mRNA CTD PMID:8603490 phloretin multiple interactions ISO EGFR (Homo sapiens) 6480464 [Ruthenium binds to Phloretin] which results in decreased expression of EGFR protein CTD PMID:34896434 phorbol 13-acetate 12-myristate multiple interactions ISO Egfr (Mus musculus) 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein more ... CTD PMID:20660715 more ... phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA CTD PMID:10516208 phorbol 13-acetate 12-myristate increases phosphorylation ISO Egfr (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein CTD PMID:26513295 phorbol 13-acetate 12-myristate increases expression ISO Egfr (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR CTD PMID:26100520 phorbol 13-acetate 12-myristate increases expression ISO EGFR (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR protein CTD PMID:19447859 and PMID:25866363 phorbol 13-acetate 12-myristate multiple interactions ISO EGFR (Homo sapiens) 6480464 naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] and pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 and PMID:25866363 phorone multiple interactions ISO Egfr (Mus musculus) 6480464 [phorone results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 phosphoramidon multiple interactions ISO EGFR (Homo sapiens) 6480464 phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 Phytolaccoside E increases expression ISO EGFR (Homo sapiens) 6480464 esculentoside A results in increased expression of EGFR protein CTD PMID:36460195 piperonyl butoxide multiple interactions ISO Egfr (Mus musculus) 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA CTD PMID:20101389 pirfenidone multiple interactions ISO EGFR (Homo sapiens) 6480464 [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation of PTPN3 protein more ... CTD PMID:28739874 pirinixic acid affects expression ISO Egfr (Mus musculus) 6480464 pirinixic acid affects the expression of EGFR mRNA CTD PMID:19136022 pirinixic acid decreases expression ISO Egfr (Mus musculus) 6480464 pirinixic acid results in decreased expression of EGFR mRNA CTD PMID:11798191 more ... pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of EGFR protein CTD PMID:2404574 pirinixic acid multiple interactions ISO Egfr (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of EGFR mRNA more ... CTD PMID:19710929 more ... piroxicam decreases expression ISO EGFR (Homo sapiens) 6480464 Piroxicam results in decreased expression of EGFR mRNA CTD PMID:21858171 piroxicam multiple interactions EXP 6480464 Piroxicam promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 platycodin D decreases expression ISO EGFR (Homo sapiens) 6480464 platycodin D results in decreased expression of EGFR protein CTD PMID:23867902 more ... platycodin D multiple interactions ISO EGFR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of EGFR protein] more ... CTD PMID:27897231 and PMID:28711525 ponatinib decreases activity ISO EGFR (Homo sapiens) 6480464 ponatinib results in decreased activity of EGFR protein mutant form CTD PMID:19878872 potassium chromate decreases expression ISO EGFR (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of EGFR mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO EGFR (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EGFR mRNA and [potassium chromate(VI) results in increased abundance of Chromates] which results in increased phosphorylation of EGFR protein CTD PMID:22079256 and PMID:32006662 primaquine multiple interactions ISO EGFR (Homo sapiens) 6480464 Primaquine inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 prochloraz multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 procymidone multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 progesterone multiple interactions ISO EGFR (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in increased expression of EGFR mRNA more ... CTD PMID:16175315 more ... progesterone multiple interactions EXP 6480464 [Estrogens co-treated with Progesterone] results in increased expression of EGFR mRNA and [Estrogens co-treated with Progesterone] results in increased expression of EGFR protein CTD PMID:21258428 progesterone increases expression EXP 6480464 Progesterone results in increased expression of EGFR mRNA CTD PMID:18591650 progesterone multiple interactions ISO Egfr (Mus musculus) 6480464 Estradiol promotes the reaction [Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein]] more ... CTD PMID:22414604 progesterone increases expression ISO EGFR (Homo sapiens) 6480464 Progesterone results in increased expression of EGFR protein CTD PMID:16175315 propofol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Propofol results in increased susceptibility to STA 9090] which results in decreased expression of EGFR protein CTD PMID:24784839 propranolol multiple interactions ISO EGFR (Homo sapiens) 6480464 Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] more ... CTD PMID:18787115 prostaglandin E2 increases secretion ISO EGFR (Homo sapiens) 6480464 EGFR protein results in increased secretion of Dinoprostone CTD PMID:16213893 prostaglandin E2 increases expression ISO EGFR (Homo sapiens) 6480464 Dinoprostone results in increased expression of EGFR protein modified form CTD PMID:30208247 prostaglandin E2 multiple interactions ISO EGFR (Homo sapiens) 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in increased expression of EGFR protein modified form] more ... CTD PMID:20850495 and PMID:30208247 prostaglandin E2 increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Dinoprostone results in increased phosphorylation of EGFR protein CTD PMID:17805209 protein kinase inhibitor multiple interactions ISO EGFR (Homo sapiens) 6480464 Protein Kinase Inhibitors inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein] CTD PMID:25303742 protoporphyrin decreases expression ISO EGFR (Homo sapiens) 6480464 protoporphyrin IX results in decreased expression of EGFR protein CTD PMID:23624237 Ptaquiloside decreases expression ISO Egfr (Mus musculus) 6480464 ptaquiloside results in decreased expression of EGFR mRNA CTD PMID:23274088 pterostilbene multiple interactions ISO EGFR (Homo sapiens) 6480464 pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 purpurin decreases expression ISO EGFR (Homo sapiens) 6480464 purpurin results in decreased expression of EGFR protein CTD PMID:33368780 pyocyanine increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Pyocyanine results in increased phosphorylation of EGFR protein CTD PMID:24015256 pyrrolidine dithiocarbamate multiple interactions ISO EGFR (Homo sapiens) 6480464 [Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 quercetin affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the susceptibility to Quercetin CTD PMID:12168845 quercetin multiple interactions ISO Egfr (Mus musculus) 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] CTD PMID:23099361 quercetin decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 more ... quercetin decreases expression ISO EGFR (Homo sapiens) 6480464 Quercetin results in decreased expression of EGFR mRNA CTD PMID:21308698 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:25164625 quercetin multiple interactions ISO EGFR (Homo sapiens) 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of EGFR mRNA more ... CTD PMID:10556937 more ... quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO EGFR (Homo sapiens) 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO EGFR (Homo sapiens) 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 quinazolines decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Quinazolines analog results in decreased phosphorylation of EGFR protein CTD PMID:10753475 quinazolines multiple interactions ISO EGFR (Homo sapiens) 6480464 Quinazolines analog inhibits the reaction [EGFR protein results in increased activity of MAPK1 protein] and Quinazolines analog inhibits the reaction [EGFR protein results in increased activity of MAPK3 protein] CTD PMID:21075094 quinolin-8-ol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Copper binds to Oxyquinoline] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 rac-lactic acid decreases expression ISO EGFR (Homo sapiens) 6480464 Lactic Acid results in decreased expression of EGFR mRNA CTD PMID:30851411 raloxifene multiple interactions ISO EGFR (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein and Raloxifene Hydrochloride results in decreased expression of and affects the localization of EGFR protein CTD PMID:18371987 and PMID:23842642 raloxifene decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased phosphorylation of EGFR protein CTD PMID:23842642 raloxifene increases phosphorylation EXP 6480464 Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein CTD PMID:24782323 ranitidine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 reactive oxygen species multiple interactions ISO Egfr (Mus musculus) 6480464 [[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein] more ... CTD PMID:23376140 reactive oxygen species multiple interactions EXP 6480464 EGFR protein affects the reaction [Reactive Oxygen Species affects the phosphorylation of SHC1 protein] CTD PMID:19168439 resveratrol multiple interactions ISO EGFR (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of EGFR mRNA more ... CTD PMID:16343977 more ... resveratrol decreases expression ISO Egfr (Mus musculus) 6480464 resveratrol results in decreased expression of EGFR mRNA CTD PMID:23525482 resveratrol decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of EGFR protein CTD PMID:20729295 and PMID:23527233 resveratrol increases activity ISO EGFR (Homo sapiens) 6480464 resveratrol results in increased activity of EGFR protein CTD PMID:15802018 resveratrol increases phosphorylation ISO EGFR (Homo sapiens) 6480464 resveratrol results in increased phosphorylation of EGFR protein CTD PMID:23527233 resveratrol affects localization ISO EGFR (Homo sapiens) 6480464 resveratrol affects the localization of EGFR protein and resveratrol affects the localization of EGFR protein modified form CTD PMID:23527233 resveratrol increases degradation ISO EGFR (Homo sapiens) 6480464 resveratrol results in increased degradation of EGFR protein CTD PMID:23527233 resveratrol multiple interactions ISO Egfr (Mus musculus) 6480464 Resveratrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] more ... CTD PMID:26100520 and PMID:27279585 resveratrol decreases expression ISO EGFR (Homo sapiens) 6480464 resveratrol results in decreased expression of EGFR mRNA and resveratrol results in decreased expression of EGFR protein CTD PMID:24514079 and PMID:25667456 resveratrol affects binding ISO EGFR (Homo sapiens) 6480464 resveratrol binds to EGFR protein CTD PMID:20729295 romidepsin decreases expression ISO EGFR (Homo sapiens) 6480464 romidepsin results in decreased expression of EGFR protein CTD PMID:15014036 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of EGFR mRNA and Rotenone results in decreased expression of EGFR protein CTD PMID:17555550 and PMID:28374803 rottlerin multiple interactions ISO EGFR (Homo sapiens) 6480464 rottlerin inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein] more ... CTD PMID:15177934 and PMID:15723263 ruthenium atom multiple interactions ISO EGFR (Homo sapiens) 6480464 [Ruthenium binds to Phloretin] which results in decreased expression of EGFR protein CTD PMID:34896434 rutin multiple interactions ISO EGFR (Homo sapiens) 6480464 Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO EGFR (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO EGFR (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of EGFR mRNA CTD PMID:35811015 SB 431542 multiple interactions ISO EGFR (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 scopolamine decreases expression EXP 6480464 Scopolamine results in decreased expression of EGFR mRNA CTD PMID:12818353 selenium atom decreases expression ISO EGFR (Homo sapiens) 6480464 Selenium results in decreased expression of EGFR mRNA CTD PMID:17390030 selenomethionine increases expression ISO EGFR (Homo sapiens) 6480464 Selenomethionine results in increased expression of EGFR mRNA CTD PMID:17205524 senecionine decreases expression ISO Egfr (Mus musculus) 6480464 senecionine results in decreased expression of EGFR protein CTD PMID:35357534 sepantronium multiple interactions ISO EGFR (Homo sapiens) 6480464 EGF protein inhibits the reaction [sepantronium results in decreased phosphorylation of EGFR protein] CTD PMID:28787001 sepantronium decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 sepantronium results in decreased phosphorylation of EGFR protein CTD PMID:28787001 serpentine asbestos decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Asbestos and Serpentine results in decreased phosphorylation of EGFR protein CTD PMID:15626777 serpentine asbestos multiple interactions ISO Egfr (Mus musculus) 6480464 N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Asbestos and Serpentine results in increased activity of EGFR protein] CTD PMID:16571779 serpentine asbestos increases activity ISO Egfr (Mus musculus) 6480464 Asbestos and Serpentine results in increased activity of EGFR protein CTD PMID:16571779 sertraline increases expression ISO EGFR (Homo sapiens) 6480464 Sertraline results in increased expression of EGFR mRNA CTD PMID:24865413 silicon dioxide increases expression ISO EGFR (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of EGFR mRNA and Silicon Dioxide results in increased expression of EGFR mRNA CTD PMID:21540303 more ... silicon dioxide increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Silicon Dioxide analog results in increased phosphorylation of EGFR protein CTD PMID:24844442 silicon dioxide increases expression ISO Egfr (Mus musculus) 6480464 Silicon Dioxide results in increased expression of EGFR mRNA CTD PMID:23221170 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]] and Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 sirolimus multiple interactions ISO Egfr (Mus musculus) 6480464 [Sirolimus results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of MAPK1 protein more ... CTD PMID:19151764 sirolimus multiple interactions ISO EGFR (Homo sapiens) 6480464 AG 1879 inhibits the reaction [Sirolimus results in increased phosphorylation of EGFR protein] CTD PMID:19151764 sodium arsenate increases expression ISO Egfr (Mus musculus) 6480464 sodium arsenate results in increased expression of EGFR mRNA CTD PMID:21795629 sodium arsenite multiple interactions ISO EGFR (Homo sapiens) 6480464 [sodium arsenite results in increased expression of EGFR protein] which results in increased phosphorylation of PCNA protein more ... CTD PMID:11723127 more ... sodium arsenite decreases phosphorylation EXP 6480464 sodium arsenite results in decreased phosphorylation of EGFR protein CTD PMID:29228391 sodium arsenite decreases expression ISO EGFR (Homo sapiens) 6480464 sodium arsenite results in decreased expression of EGFR mRNA CTD PMID:28595984 sodium arsenite affects methylation ISO EGFR (Homo sapiens) 6480464 sodium arsenite affects the methylation of EGFR gene CTD PMID:28589171 sodium arsenite increases activity ISO EGFR (Homo sapiens) 6480464 sodium arsenite results in increased activity of EGFR protein CTD PMID:19414066 sodium arsenite increases expression ISO EGFR (Homo sapiens) 6480464 sodium arsenite results in increased expression of EGFR mRNA and sodium arsenite results in increased expression of EGFR protein CTD PMID:12016162 and PMID:25907674 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of EGFR protein CTD PMID:9710602 sodium arsenite multiple interactions EXP 6480464 [EGF protein results in decreased expression of EGFR protein] inhibits the reaction [sodium arsenite results in increased activity of MAPK1 protein] more ... CTD PMID:29228391 and PMID:9710602 sodium arsenite increases expression ISO Egfr (Mus musculus) 6480464 sodium arsenite results in increased expression of EGFR mRNA CTD PMID:17077188 and PMID:9846968 sodium arsenite multiple interactions ISO Egfr (Mus musculus) 6480464 sodium arsenite promotes the reaction [SRC protein binds to EGFR protein] and sodium arsenite results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:11723127 sodium arsenite decreases expression ISO Egfr (Mus musculus) 6480464 sodium arsenite results in decreased expression of EGFR mRNA and sodium arsenite results in decreased expression of EGFR protein CTD PMID:16507464 and PMID:19822182 sodium arsenite increases phosphorylation ISO EGFR (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of EGFR protein CTD PMID:10564177 more ... sodium arsenite affects expression ISO Egfr (Mus musculus) 6480464 sodium arsenite affects the expression of EGFR mRNA CTD PMID:16507464 sodium chloride increases phosphorylation ISO Egfr (Mus musculus) 6480464 Sodium Chloride results in increased phosphorylation of EGFR protein CTD PMID:21568938 sodium chloride multiple interactions ISO Egfr (Mus musculus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sodium Chloride results in increased phosphorylation of EGFR protein] more ... CTD PMID:21568938 sodium fluoride decreases expression ISO Egfr (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of EGFR mRNA CTD PMID:37245782 sodium hydroxide affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 sorafenib decreases expression ISO EGFR (Homo sapiens) 6480464 sorafenib results in decreased expression of EGFR mRNA CTD PMID:26409325 sotorasib increases phosphorylation ISO EGFR (Homo sapiens) 6480464 sotorasib results in increased phosphorylation of EGFR protein CTD PMID:31666701 sphingosine 1-phosphate multiple interactions ISO EGFR (Homo sapiens) 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of EGFR protein] CTD PMID:26518876 sphingosine 1-phosphate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 sphingosine 1-phosphate results in increased phosphorylation of EGFR protein CTD PMID:26518876 staurosporine multiple interactions ISO EGFR (Homo sapiens) 6480464 Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 stilbenoid multiple interactions ISO EGFR (Homo sapiens) 6480464 Stilbenes analog results in decreased expression of and results in decreased phosphorylation of EGFR protein CTD PMID:25063218 SU6656 multiple interactions ISO EGFR (Homo sapiens) 6480464 SU 6656 inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15504454 SU6656 multiple interactions ISO Egfr (Mus musculus) 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] and [SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:23376140 succimer multiple interactions ISO EGFR (Homo sapiens) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of EGFR mRNA CTD PMID:26378955 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of EGFR mRNA CTD PMID:30047161 sulfasalazine multiple interactions ISO EGFR (Homo sapiens) 6480464 [Sulfasalazine co-treated with celastrol] affects the expression of EGFR protein more ... CTD PMID:20007406 sulfasalazine decreases expression ISO Egfr (Mus musculus) 6480464 Sulfasalazine results in decreased expression of EGFR mRNA and Sulfasalazine results in decreased expression of EGFR protein CTD PMID:31830553 sulindac sulfide multiple interactions ISO EGFR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein] and Chloroquine inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein] CTD PMID:20332299 sulindac sulfide decreases expression ISO EGFR (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of EGFR protein CTD PMID:20332299 sulindac sulfide increases ubiquitination ISO EGFR (Homo sapiens) 6480464 sulindac sulfide results in increased ubiquitination of EGFR protein CTD PMID:20332299 sulindac sulfide increases phosphorylation ISO EGFR (Homo sapiens) 6480464 sulindac sulfide results in increased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfide decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 sulindac sulfide results in decreased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone multiple interactions ISO EGFR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein] and Chloroquine inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein] CTD PMID:20332299 sulindac sulfone increases ubiquitination ISO EGFR (Homo sapiens) 6480464 sulindac sulfone results in increased ubiquitination of EGFR protein CTD PMID:20332299 sulindac sulfone multiple interactions EXP 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein and [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein modified form CTD PMID:17908994 sulindac sulfone increases phosphorylation ISO EGFR (Homo sapiens) 6480464 sulindac sulfone results in increased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 sulindac sulfone results in decreased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone decreases expression ISO EGFR (Homo sapiens) 6480464 sulindac sulfone results in decreased expression of EGFR protein CTD PMID:20332299 Sulpyrine multiple interactions EXP 6480464 Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 sunitinib decreases expression ISO EGFR (Homo sapiens) 6480464 Sunitinib results in decreased expression of EGFR mRNA CTD PMID:31533062 suramin multiple interactions EXP 6480464 Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of EGFR protein] CTD PMID:9710602 taiwanin C decreases phosphorylation ISO Egfr (Mus musculus) 6480464 taiwanin C results in decreased phosphorylation of EGFR protein CTD PMID:26537528 and PMID:30884126 tamoxifen decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein results in decreased susceptibility to Tamoxifen CTD PMID:15665275 and PMID:16000581 tamoxifen affects expression ISO Egfr (Mus musculus) 6480464 Tamoxifen affects the expression of EGFR mRNA CTD PMID:17555576 tamoxifen increases expression ISO EGFR (Homo sapiens) 6480464 Tamoxifen results in increased expression of EGFR mRNA and Tamoxifen results in increased expression of EGFR protein CTD PMID:20005069 tamoxifen multiple interactions ISO EGFR (Homo sapiens) 6480464 [EGF protein results in increased activity of EGFR protein] which results in decreased susceptibility to Tamoxifen more ... CTD PMID:19347870 and PMID:24758408 tanespimycin decreases expression ISO EGFR (Homo sapiens) 6480464 tanespimycin analog results in decreased expression of EGFR protein and tanespimycin results in decreased expression of EGFR protein CTD PMID:17010675 more ... tanespimycin multiple interactions ISO EGFR (Homo sapiens) 6480464 tanespimycin results in increased degradation of and results in decreased expression of EGFR protein CTD PMID:16061882 taurocholic acid increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Taurocholic Acid results in increased phosphorylation of EGFR protein CTD PMID:26518876 taurocholic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 JTE 013 inhibits the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein] and S1PR2 mRNA promotes the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:26518876 tephrosin affects localization ISO EGFR (Homo sapiens) 6480464 tephrosin affects the localization of EGFR protein CTD PMID:20056314 tephrosin multiple interactions ISO EGFR (Homo sapiens) 6480464 Chloroquine inhibits the reaction [tephrosin results in increased degradation of EGFR protein] more ... CTD PMID:20056314 Terfenadine multiple interactions ISO EGFR (Homo sapiens) 6480464 11 more ... CTD PMID:19289568 Terfenadine decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Terfenadine analog results in decreased phosphorylation of EGFR protein CTD PMID:19289568 teriflunomide multiple interactions ISO EGFR (Homo sapiens) 6480464 teriflunomide inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:30364229 tert-butyl hydroperoxide multiple interactions ISO EGFR (Homo sapiens) 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA and MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA] CTD PMID:35690295 testosterone multiple interactions EXP 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein more ... CTD PMID:17272394 more ... testosterone increases phosphorylation EXP 6480464 Testosterone results in increased phosphorylation of EGFR protein CTD PMID:21177760 testosterone increases expression ISO EGFR (Homo sapiens) 6480464 Testosterone results in increased expression of EGFR mRNA CTD PMID:21592394 testosterone multiple interactions ISO EGFR (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EGFR mRNA CTD PMID:21592394 testosterone increases expression ISO Egfr (Mus musculus) 6480464 Testosterone deficiency results in increased expression of EGFR mRNA and Testosterone results in increased expression of EGFR mRNA CTD PMID:21669218 and PMID:33848595 Tetrachlorobisphenol A multiple interactions ISO EGFR (Homo sapiens) 6480464 4-(6-bromo-1 more ... CTD PMID:36190352 Tetrachlorobisphenol A increases expression ISO EGFR (Homo sapiens) 6480464 tetrachlorodian results in increased expression of EGFR mRNA CTD PMID:33582643 and PMID:36190352 tetrachloromethane multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein more ... CTD PMID:18006644 and PMID:29923357 tetrachloromethane decreases expression ISO Egfr (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of EGFR mRNA CTD PMID:29987408 tetrachloromethane increases expression ISO Egfr (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of EGFR mRNA and Carbon Tetrachloride results in increased expression of EGFR protein CTD PMID:17484886 and PMID:27477297 tetrachloromethane multiple interactions ISO Egfr (Mus musculus) 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]] more ... CTD PMID:27477297 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of EGFR mRNA CTD PMID:16644059 and PMID:18006644 tetracycline decreases expression ISO Egfr (Mus musculus) 6480464 Tetracycline results in decreased expression of EGFR mRNA CTD PMID:24489787 tetramethylpyrazine multiple interactions ISO Egfr (Mus musculus) 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]] more ... CTD PMID:27477297 tetraphene multiple interactions ISO Egfr (Mus musculus) 6480464 AHR protein affects the reaction [benz(a)anthracene inhibits the reaction [EGF protein binds to EGFR protein]] and benz(a)anthracene inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 tetrathiomolybdate(2-) multiple interactions ISO EGFR (Homo sapiens) 6480464 tetrathiomolybdate inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18480265 thapsigargin increases expression ISO Egfr (Mus musculus) 6480464 Thapsigargin results in increased expression of EGFR protein CTD PMID:24648495 theaflavin multiple interactions ISO Egfr (Mus musculus) 6480464 theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] CTD PMID:27058323 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of EGFR mRNA CTD PMID:23411599 and PMID:34492290 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EGFR mRNA CTD PMID:28943392 toluene 2,4-diisocyanate multiple interactions ISO EGFR (Homo sapiens) 6480464 EGFR protein affects the reaction [[Toluene 2 more ... CTD PMID:16908450 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EGFR mRNA CTD PMID:25729387 topotecan decreases expression ISO Egfr (Mus musculus) 6480464 Topotecan results in decreased expression of EGFR protein CTD PMID:15923621 topotecan multiple interactions ISO EGFR (Homo sapiens) 6480464 [RTKI cpd results in decreased activity of EGFR protein] which results in decreased susceptibility to Topotecan CTD PMID:15923621 topotecan decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 Topotecan results in decreased phosphorylation of EGFR protein CTD PMID:15923621 topotecan decreases expression ISO EGFR (Homo sapiens) 6480464 Topotecan results in decreased expression of EGFR mRNA and Topotecan results in decreased expression of EGFR protein CTD PMID:15923621 torin 1 multiple interactions ISO EGFR (Homo sapiens) 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 more ... CTD PMID:26455392 trans-piceid multiple interactions ISO EGFR (Homo sapiens) 6480464 polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 triamterene affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR gene SNP affects the susceptibility to Triamterene CTD PMID:25622337 trichloroethene decreases expression ISO Egfr (Mus musculus) 6480464 Trichloroethylene results in decreased expression of EGFR mRNA CTD PMID:15363585 more ... trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of EGFR gene CTD PMID:27618143 trichostatin A increases expression ISO EGFR (Homo sapiens) 6480464 trichostatin A results in increased expression of EGFR mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO EGFR (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of EGFR mRNA CTD PMID:30589522 triphenyl phosphate increases expression ISO EGFR (Homo sapiens) 6480464 triphenyl phosphate results in increased expression of EGFR mRNA CTD PMID:35776891 Triptolide decreases expression ISO Egfr (Mus musculus) 6480464 triptolide results in decreased expression of EGFR mRNA CTD PMID:32835833 troglitazone multiple interactions ISO EGFR (Homo sapiens) 6480464 [Troglitazone co-treated with 4-((3-bromophenyl)amino)-6 and 7-dimethoxyquinazoline] results in decreased expression of EGFR protein CTD PMID:32822399 troglitazone affects expression ISO EGFR (Homo sapiens) 6480464 Troglitazone affects the expression of EGFR mRNA CTD PMID:32822399 troglitazone decreases expression ISO EGFR (Homo sapiens) 6480464 Troglitazone results in decreased expression of EGFR protein CTD PMID:32822399 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO EGFR (Homo sapiens) 6480464 Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 trovafloxacin multiple interactions ISO Egfr (Mus musculus) 6480464 [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of EGFR mRNA CTD PMID:18930950 tyrphostin AG 1478 multiple interactions ISO EGFR (Homo sapiens) 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] more ... CTD PMID:15177934 more ... tyrphostin AG 1478 decreases expression ISO EGFR (Homo sapiens) 6480464 RTKI cpd results in decreased expression of EGFR protein modified form CTD PMID:29974605 tyrphostin AG 1478 decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 RTKI cpd results in decreased phosphorylation of EGFR protein CTD PMID:15923621 more ... tyrphostin AG 1478 decreases activity ISO EGFR (Homo sapiens) 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:27071941 tyrphostin AG 1478 decreases activity EXP 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:15574683 tyrphostin AG 1478 multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Genistein results in increased secretion of Testosterone] more ... CTD PMID:15459120 more ... tyrphostin AG 1478 decreases activity ISO Egfr (Mus musculus) 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:12794006 tyrphostin AG 1478 multiple interactions ISO Egfr (Mus musculus) 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:18758753 more ... U-73122 multiple interactions ISO EGFR (Homo sapiens) 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:15177934 urethane multiple interactions ISO Egfr (Mus musculus) 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of EGFR mRNA and IFNG protein promotes the reaction [Urethane results in increased expression of EGFR mRNA] CTD PMID:12400877 and PMID:12810352 urethane decreases expression ISO EGFR (Homo sapiens) 6480464 Urethane results in decreased expression of EGFR mRNA CTD PMID:28818685 urethane increases expression ISO Egfr (Mus musculus) 6480464 Urethane results in increased expression of EGFR mRNA CTD PMID:12400877 ursodeoxycholic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:14747693 ursolic acid multiple interactions ISO Egfr (Mus musculus) 6480464 resveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] more ... CTD PMID:26100520 UTP increases phosphorylation EXP 6480464 Uridine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:14676212 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of EGFR mRNA CTD PMID:24136188 valproic acid decreases methylation ISO EGFR (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of EGFR gene CTD PMID:29154799 valproic acid multiple interactions ISO EGFR (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 valproic acid increases expression ISO EGFR (Homo sapiens) 6480464 Valproic Acid results in increased expression of EGFR mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO Egfr (Mus musculus) 6480464 Valproic Acid results in decreased expression of EGFR mRNA CTD PMID:24535564 vanadyl sulfate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 vanadyl sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 and PMID:11943669 vandetanib affects response to substance ISO EGFR (Homo sapiens) 6480464 EGFR affects the susceptibility to vandetanib CTD PMID:15604279 vandetanib decreases activity ISO EGFR (Homo sapiens) 6480464 vandetanib results in decreased activity of EGFR protein CTD PMID:15596048 vandetanib decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 vandetanib results in decreased phosphorylation of EGFR protein CTD PMID:21350000 veliparib decreases response to substance ISO EGFR (Homo sapiens) 6480464 EGFR protein results in decreased susceptibility to veliparib CTD PMID:21912620 veliparib affects localization ISO EGFR (Homo sapiens) 6480464 veliparib affects the localization of EGFR protein CTD PMID:21719137 vinclozolin multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of EGFR gene CTD PMID:31682807 vitamin E decreases expression ISO EGFR (Homo sapiens) 6480464 Vitamin E results in decreased expression of EGFR mRNA CTD PMID:19244175 vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of EGFR mRNA and vorinostat results in decreased expression of EGFR protein CTD PMID:21389970 vorinostat decreases phosphorylation ISO EGFR (Homo sapiens) 6480464 vorinostat results in decreased phosphorylation of EGFR protein CTD PMID:20531243 WIN 55212-2 multiple interactions ISO EGFR (Homo sapiens) 6480464 RTKI cpd inhibits the reaction [(3R)-((2 more ... CTD PMID:20619260 WIN 55212-2 increases phosphorylation ISO EGFR (Homo sapiens) 6480464 (3R)-((2 more ... CTD PMID:20619260 wortmannin multiple interactions ISO EGFR (Homo sapiens) 6480464 Wortmannin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:15177934 more ... wortmannin multiple interactions ISO Egfr (Mus musculus) 6480464 wortmannin inhibits the reaction [Sodium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:21568938 zinc atom multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:12915106 more ... zinc atom increases phosphorylation ISO Egfr (Mus musculus) 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:11983694 zinc atom increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:12915106 more ... zinc atom multiple interactions ISO Egfr (Mus musculus) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:11983694 and PMID:33549593 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of EGFR mRNA CTD PMID:12672911 zinc dichloride increases phosphorylation ISO EGFR (Homo sapiens) 6480464 zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 zinc sulfate multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:16410015 zinc sulfate increases phosphorylation EXP 6480464 Zinc Sulfate results in increased phosphorylation of EGFR protein CTD PMID:19946718 zinc sulfate increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Zinc Sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 and PMID:11943669 zinc(0) multiple interactions ISO EGFR (Homo sapiens) 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:12915106 more ... zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of EGFR mRNA CTD PMID:12672911 zinc(0) multiple interactions ISO Egfr (Mus musculus) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:11983694 and PMID:33549593 zinc(0) increases phosphorylation ISO EGFR (Homo sapiens) 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:12915106 more ... zinc(0) increases phosphorylation ISO Egfr (Mus musculus) 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:11983694