(+)-artemisinin increases expression ISO RGD:10451 6480464 artemisinin results in increased expression of CYP2E1 mRNA CTD PMID:17962186 (+)-catechin multiple interactions ISO RGD:1345007 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CYP2E1 mRNA, Catechin inhibits the reaction [Ethanol results in increased expression of CYP2E1] CTD PMID:21352821 , PMID:24763279 (+)-catechin multiple interactions ISO RGD:10451 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2E1 mRNA CTD PMID:25663641 (+)-epicatechin-3-O-gallate multiple interactions ISO RGD:10451 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2E1 mRNA CTD PMID:25663641 (+)-schisandrin B decreases activity ISO RGD:10451 6480464 schizandrin B results in decreased activity of CYP2E1 protein CTD PMID:25753323 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA] CTD PMID:31150632 (+)-taxifolin decreases expression ISO RGD:1345007 6480464 taxifolin results in decreased expression of CYP2E1 mRNA CTD PMID:17541156 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:10451 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2E1 mRNA, epigallocatechin gallate results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:14600287 , PMID:25663641 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1345007 6480464 epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein] CTD PMID:24508477 (-)-epigallocatechin 3-gallate affects binding EXP 6480464 epigallocatechin gallate binds to CYP2E1 protein CTD PMID:23010222 (-)-trans-epsilon-viniferin decreases activity ISO RGD:1345007 6480464 epsilon-viniferin results in decreased activity of CYP2E1 protein CTD PMID:12818727 (2-hydroxyphenyl)acetic acid multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of coumarin] which results in increased abundance of 2-hydroxyphenylacetic acid CTD PMID:34334558 (R)-carnitine multiple interactions EXP 6480464 Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:8130774 (R)-lipoic acid multiple interactions ISO RGD:10451 6480464 Thioctic Acid affects the reaction [cyanoginosin LR affects the expression of CYP2E1 protein] CTD PMID:32061150 (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] more ... CTD PMID:26332274 , PMID:27919644 (R,R,R)-alpha-tocopherol increases expression ISO RGD:1345007 6480464 alpha-Tocopherol results in increased expression of CYP2E1 mRNA CTD PMID:28062356 (R,R,R)-alpha-tocopherol increases expression EXP 6480464 alpha-Tocopherol results in increased expression of CYP2E1 mRNA CTD PMID:26332274 (S)-mandelic acid multiple interactions ISO RGD:1345007 6480464 CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 (S)-naringenin decreases activity ISO RGD:1345007 6480464 naringenin results in decreased activity of CYP2E1 protein CTD PMID:33007396 (S)-naringenin decreases activity EXP 6480464 naringenin results in decreased activity of CYP2E1 protein CTD PMID:33007396 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of CYP2E1 protein CTD PMID:16434548 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of 1 more ... CTD PMID:9047321 1,1,1-trichloroethane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 1 more ... CTD PMID:1664256 1,1-Dichloroethane multiple interactions EXP 6480464 1, 1-dichloroethane results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:11606809 1,1-Dichloroethane increases expression EXP 6480464 1, 1-dichloroethane results in increased expression of CYP2E1 protein CTD PMID:11606809 1,1-Dichloroethane increases activity EXP 6480464 1, 1-dichloroethane results in increased activity of CYP2E1 protein CTD PMID:11606809 1,1-dichloroethene multiple interactions ISO RGD:1345007 6480464 diallyl sulfone inhibits the reaction [CYP2E1 protein results in increased metabolism of vinylidene chloride] CTD PMID:10215634 1,1-dichloroethene increases expression ISO RGD:10451 6480464 vinylidene chloride results in increased expression of CYP2E1 protein CTD PMID:26682919 1,1-dichloroethene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of vinylidene chloride CTD PMID:10215634 , PMID:15319346 1,1-dichloroethene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of vinylidene chloride CTD PMID:11356946 , PMID:15319346 1,1-dichloroethene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of vinylidene chloride CTD PMID:15319346 1,2,3,5-tetrachlorobenzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 1 more ... CTD PMID:7747284 1,2,3,5-tetrachlorobenzene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 1 more ... CTD PMID:7747284 1,2,4,5-tetrachlorobenzene increases expression EXP 6480464 1 more ... CTD PMID:10696772 1,2,4-trichlorobenzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 1 more ... CTD PMID:7747284 1,2,4-trichlorobenzene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 1 more ... CTD PMID:7747284 1,2-dibromoethane increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Ethylene Dibromide CTD PMID:10841534 , PMID:18350910 1,2-dibromoethane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Ethylene Dibromide CTD PMID:1664256 1,2-dichlorobenzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:7747284 , PMID:9817075 1,2-dichlorobenzene multiple interactions EXP 6480464 [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein more ... CTD PMID:24713513 , PMID:9817075 1,2-dichlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:9817075 1,2-dichlorobenzene multiple interactions ISO RGD:10451 6480464 [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene, dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] CTD PMID:9817075 1,2-dichlorobenzene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 2-dichlorobenzene CTD PMID:7747284 1,2-dichloroethane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of ethylene dichloride CTD PMID:1664256 1,2-dichloroethane increases expression ISO RGD:10451 6480464 ethylene dichloride results in increased expression of CYP2E1 mRNA, ethylene dichloride results in increased expression of CYP2E1 protein CTD PMID:27301210 more ... 1,2-dichloroethane multiple interactions ISO RGD:10451 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of CYP2E1 protein more ... CTD PMID:27301210 , PMID:30664321 1,2-dichloroethene decreases expression EXP 6480464 1, 2-dichloroethylene results in decreased expression of CYP2E1 protein CTD PMID:9671540 1,2-dichloroethene multiple interactions ISO RGD:10451 6480464 1 more ... CTD PMID:10828257 1,2-dichloroethene multiple interactions EXP 6480464 1 more ... CTD PMID:7871537 , PMID:9851676 1,2-dichloroethene decreases activity ISO RGD:1345007 6480464 1, 2-dichloroethylene results in decreased activity of CYP2E1 protein CTD PMID:32199159 1,2-dichloroethene decreases activity EXP 6480464 1, 2-dichloroethylene results in decreased activity of CYP2E1 protein CTD PMID:15205388 more ... 1,2-dimethylhydrazine multiple interactions EXP 6480464 asiatic acid inhibits the reaction [1 more ... CTD PMID:19497424 more ... 1,2-dimethylhydrazine increases expression EXP 6480464 1, 2-Dimethylhydrazine results in increased expression of CYP2E1 protein CTD PMID:30720227 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of CYP2E1 mRNA CTD PMID:32387197 1,2-dimethylhydrazine increases activity EXP 6480464 1, 2-Dimethylhydrazine results in increased activity of CYP2E1 protein CTD PMID:19497424 , PMID:29108773 1,4-benzoquinone decreases expression EXP 6480464 quinone results in decreased expression of CYP2E1 protein CTD PMID:10462055 1,4-dichlorobenzene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 4-dichlorobenzene CTD PMID:7747284 1,4-dichlorobenzene multiple interactions EXP 6480464 [Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene CTD PMID:9051121 1,4-dichlorobenzene increases expression EXP 6480464 4-dichlorobenzene results in increased expression of CYP2E1 protein CTD PMID:10696772 1,4-dichlorobenzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 4-dichlorobenzene CTD PMID:7747284 , PMID:9817075 1,4-dioxane multiple interactions EXP 6480464 1, 4-dioxane results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15490126 1,4-dioxane increases expression EXP 6480464 1, 4-dioxane results in increased expression of CYP2E1 mRNA CTD PMID:15490126 1,4-dioxane increases activity EXP 6480464 1, 4-dioxane results in increased activity of CYP2E1 protein CTD PMID:15490126 1,4-naphthoquinone increases abundance ISO RGD:1345007 6480464 CYP2E1 protein results in increased abundance of 1, 4-naphthoquinone CTD PMID:16243959 1-benzylpiperazine decreases expression EXP 6480464 N-benzylpiperazine results in decreased expression of CYP2E1 mRNA CTD PMID:26821219 1-bromopropane increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to 1-bromopropane CTD PMID:19638432 1-bromopropane increases expression EXP 6480464 1-bromopropane results in increased expression of CYP2E1 CTD PMID:30247689 1-bromopropane multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1] CTD PMID:30247689 1-Methylpyrene multiple interactions ISO RGD:1345007 6480464 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] more ... CTD PMID:25243916 , PMID:27913846 1-naphthol increases abundance ISO RGD:1345007 6480464 CYP2E1 protein results in increased abundance of 1-naphthol CTD PMID:16243959 1-naphthyl isothiocyanate decreases expression ISO RGD:10451 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP2E1 mRNA CTD PMID:15913567 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP2E1 mRNA CTD PMID:30723492 17beta-estradiol decreases expression ISO RGD:1345007 6480464 Estradiol results in decreased expression of CYP2E1 mRNA CTD PMID:20106945 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Plant Preparations] results in decreased expression of CYP2E1 mRNA CTD PMID:26945725 17beta-estradiol decreases expression ISO RGD:10451 6480464 Estradiol results in decreased expression of CYP2E1 mRNA CTD PMID:19484750 17beta-estradiol increases activity ISO RGD:1345007 6480464 Estradiol results in increased activity of CYP2E1 protein CTD PMID:22837389 19(S)-HETE affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of 19-hydroxy-5 more ... CTD PMID:15205388 19-HETE affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of 19-hydroxy-5 more ... CTD PMID:15205388 1H-imidazole increases expression EXP 6480464 imidazole results in increased expression of CYP2E1 protein CTD PMID:3337723 1H-pyrazole increases expression ISO RGD:1345007 6480464 pyrazole results in increased expression of CYP2E1 protein CTD PMID:8074729 1H-pyrazole increases expression EXP 6480464 pyrazole results in increased expression of CYP2E1 protein CTD PMID:3113478 more ... 1H-pyrazole increases activity EXP 6480464 pyrazole results in increased activity of CYP2E1 protein CTD PMID:3782137 , PMID:8734847 1H-pyrazole affects expression ISO RGD:10451 6480464 pyrazole affects the expression of CYP2E1 protein CTD PMID:19679878 1H-pyrazole increases expression ISO RGD:10451 6480464 pyrazole results in increased expression of CYP2E1 protein CTD PMID:9698299 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:1345007 6480464 2 more ... CTD PMID:26808241 2,2',4,5-tetrachlorobiphenyl multiple interactions ISO RGD:1345007 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2 more ... CTD PMID:27913846 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1345007 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2 more ... CTD PMID:27913846 2,3,5,6-tetrachlorophenol increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2 more ... CTD PMID:7747284 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10451 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA CTD PMID:17949056 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10451 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP2E1 gene] CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1345007 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA] more ... CTD PMID:26159488 , PMID:28673560 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1345007 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 more ... CTD PMID:20106945 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345007 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA CTD PMID:23669205 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 protein CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1345007 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10451 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA CTD PMID:19770486 , PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10451 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA CTD PMID:16120747 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA CTD PMID:19969063 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of CYP2E1 mRNA CTD PMID:21602191 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO RGD:10451 6480464 2 more ... CTD PMID:25768209 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein CTD PMID:18079364 2,6-dimethylaniline multiple interactions ISO RGD:1345007 6480464 fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of 2, 6-xylidine metabolite] CTD PMID:11409937 2,6-dimethylaniline affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of 2, 6-xylidine metabolite CTD PMID:11409937 2,6-dimethylnaphthalene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2, 6-dimethylnaphthalene CTD PMID:17156750 2-acetamidofluorene multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:14656948 more ... 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene analog results in increased expression of CYP2E1 protein, 2-Acetylaminofluorene results in increased expression of CYP2E1 protein CTD PMID:15916741 , PMID:23665045 2-amino-2-deoxy-D-galactopyranose decreases expression EXP 6480464 Galactosamine results in decreased expression of CYP2E1 protein CTD PMID:16208626 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 [lipopolysaccharide more ... CTD PMID:35838105 2-chloroethanol increases expression EXP 6480464 Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA, Ethylene Chlorohydrin results in increased expression of CYP2E1 protein CTD PMID:31585129 2-chloroethanol multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA] more ... CTD PMID:31585129 2-naphthol increases abundance ISO RGD:1345007 6480464 CYP2E1 protein results in increased abundance of 2-naphthol CTD PMID:16243959 2-nitroanisole increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 2-nitroanisole CTD PMID:15144223 2-nitroanisole increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2-nitroanisole CTD PMID:17159769 , PMID:21218109 2-nitroanisole increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-nitroanisole CTD PMID:21218109 2-nitrophenol increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-nitrophenol CTD PMID:20027144 2-nitrophenol affects chemical synthesis EXP 6480464 CYP2E1 protein affects the chemical synthesis of 2-nitrophenol CTD PMID:11409192 2-nitrophenol increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2-nitrophenol CTD PMID:17159769 2-nitrophenol affects chemical synthesis ISO RGD:1345007 6480464 CYP2E1 protein affects the chemical synthesis of 2-nitrophenol CTD PMID:11409192 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:19692669 , PMID:23196670 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [3 more ... CTD PMID:34256052 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:34256052 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:1345007 6480464 3 more ... CTD PMID:28673560 3,3',5-triiodo-L-thyronine increases activity EXP 6480464 Triiodothyronine results in increased activity of CYP2E1 protein CTD PMID:14631868 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of CYP2E1 protein CTD PMID:14631868 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol decreases activity ISO RGD:1345007 6480464 fluorotelomer alcohols results in decreased activity of CYP2E1 protein CTD PMID:35121066 3,4-dihydroxybenzoic acid multiple interactions EXP 6480464 [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein CTD PMID:15302093 3,4-dihydroxybenzoic acid decreases activity EXP 6480464 protocatechuic acid results in decreased activity of CYP2E1 protein CTD PMID:15302093 3,4-methylenedioxymethamphetamine increases expression ISO RGD:10451 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of CYP2E1 mRNA CTD PMID:26251327 3-(Methylthio)-1-propene decreases expression EXP 6480464 allyl methyl sulfide results in decreased expression of CYP2E1 protein CTD PMID:16000231 , PMID:8117321 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of CYP2E1 protein CTD PMID:34915118 3-methylcholanthrene multiple interactions EXP 6480464 [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:15302093 more ... 3-methylcholanthrene decreases expression ISO RGD:10451 6480464 Methylcholanthrene results in decreased expression of CYP2E1 mRNA CTD PMID:30503582 3-methylcholanthrene decreases expression ISO RGD:1345007 6480464 Methylcholanthrene results in decreased expression of CYP2E1 mRNA CTD PMID:28673560 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of CYP2E1 mRNA, Methylcholanthrene results in increased expression of CYP2E1 protein CTD PMID:10476907 more ... 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of CYP2E1 mRNA, Methylcholanthrene results in decreased expression of CYP2E1 protein CTD PMID:3113478 more ... 3-methylcholanthrene decreases activity EXP 6480464 Methylcholanthrene results in decreased activity of CYP2E1 protein CTD PMID:8734847 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:12920169 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:12115524 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases activity EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CYP2E1 protein CTD PMID:9774145 4-hydroxy-TEMPO multiple interactions EXP 6480464 tempol inhibits the reaction [CYP2E1 protein results in increased reduction of Tirapazamine] CTD PMID:7710944 4-methylumbelliferone multiple interactions ISO RGD:10451 6480464 Hymecromone inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein] CTD PMID:24661945 4-nitrocatechol multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol more ... CTD PMID:31870919 4-nitrocatechol increases chemical synthesis EXP 6480464 CYP2E1 protein results in increased chemical synthesis of 4-nitrocatechol CTD PMID:31870919 4-nitrocatechol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol, notopterol inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol] CTD PMID:32198085 4-nitrophenol multiple interactions ISO RGD:1345007 6480464 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] more ... CTD PMID:10215755 more ... 4-nitrophenol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-nitrophenol CTD PMID:15763544 more ... 4-nitrophenol increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:11408273 more ... 4-nitrophenol increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 4-nitrophenol CTD PMID:10207612 more ... 4-nitrophenol increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:14669323 more ... 4-nitrophenol multiple interactions EXP 6480464 2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] more ... CTD PMID:1538706 more ... 4-nitrophenol increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:10094576 , PMID:15742976 4-nitrophenol increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 4-nitrophenol CTD PMID:12464242 more ... 4-nitrophenol affects binding ISO RGD:1345007 6480464 4-nitrophenol binds to CYP2E1 protein CTD PMID:24924949 4-Vinylcyclohexene multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene] which results in increased abundance of 1, 2-epoxy-4-vinylcyclohexane CTD PMID:11368546 4-Vinylcyclohexene increases expression ISO RGD:10451 6480464 4-vinylcyclohexene results in increased expression of CYP2E1 protein CTD PMID:9929517 4-Vinylcyclohexene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene CTD PMID:11368546 4-vinylcyclohexene dioxide affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to 4-vinyl-1-cyclohexene dioxide CTD PMID:18622027 5,7-dihydroxy-4'-methoxyflavone decreases activity EXP 6480464 acacetin results in decreased activity of CYP2E1 protein CTD PMID:32738202 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO RGD:10451 6480464 Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA] more ... CTD PMID:21684301 more ... 5-(2-chloroethyl)-4-methylthiazole decreases activity ISO RGD:1345007 6480464 Chlormethiazole results in decreased activity of CYP2E1 protein CTD PMID:26599973 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO RGD:1345007 6480464 [Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone, Chlormethiazole inhibits the reaction [Docosahexaenoic Acids results in increased expression of CYP2E1 protein] CTD PMID:16963249 , PMID:26599973 5-(2-chloroethyl)-4-methylthiazole decreases expression ISO RGD:1345007 6480464 Chlormethiazole results in decreased expression of CYP2E1 protein CTD PMID:16963249 5-(2-chloroethyl)-4-methylthiazole decreases expression EXP 6480464 Chlormethiazole results in decreased expression of CYP2E1 mRNA, Chlormethiazole results in decreased expression of CYP2E1 protein CTD PMID:10751552 , PMID:7601153 5-(2-chloroethyl)-4-methylthiazole multiple interactions EXP 6480464 Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol], Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] CTD PMID:7601153 5-(2-chloroethyl)-4-methylthiazole decreases activity EXP 6480464 Chlormethiazole results in decreased activity of CYP2E1 protein CTD PMID:16330492 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO RGD:1345007 6480464 Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 5-methoxy-N,N-diisopropyltryptamine multiple interactions ISO RGD:1345007 6480464 [5-methoxy-N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 5-methoxy-N,N-diisopropyltryptamine decreases activity ISO RGD:1345007 6480464 5-methoxy-N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein CTD PMID:26599973 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO RGD:1345007 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:30611723 6-Hydroxychlorzoxazone increases abundance ISO RGD:10451 6480464 CYP2E1 protein results in increased abundance of 6-hydroxychlorzoxazone CTD PMID:31501917 6-Hydroxychlorzoxazone multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone, [Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazone CTD PMID:28438436 6-Hydroxychlorzoxazone multiple interactions ISO RGD:1345007 6480464 [CYP2E1 mRNA results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone more ... CTD PMID:21915887 more ... 6-Hydroxychlorzoxazone increases chemical synthesis ISO RGD:1345007 6480464 CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone CTD PMID:12401345 more ... 6-Hydroxychlorzoxazone increases chemical synthesis EXP 6480464 CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone CTD PMID:28438436 6-Hydroxychlorzoxazone multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased abundance of 6-hydroxychlorzoxazone, [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone CTD PMID:30503582 , PMID:31501917 6-Hydroxychlorzoxazone increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of 6-hydroxychlorzoxazone CTD PMID:19900514 7,12-dimethyltetraphene affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to 9 more ... CTD PMID:18622027 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:24576726 7,8-dihydroxycoumarin multiple interactions EXP 6480464 daphnetin inhibits the reaction [Benzene results in increased expression of CYP2E1 mRNA] CTD PMID:33749080 7-ethoxycoumarin increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 7-ethoxycoumarin CTD PMID:18385292 8-Br-cAMP increases expression ISO RGD:1345007 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP2E1 mRNA CTD PMID:22079614 8-Epidiosbulbin E acetate decreases expression ISO RGD:10451 6480464 8-epidiosbulbin E acetate results in decreased expression of CYP2E1 mRNA CTD PMID:31626840 abamectin increases expression EXP 6480464 abamectin results in increased expression of CYP2E1 protein CTD PMID:31739238 abamectin multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein] more ... CTD PMID:31739238 acadesine multiple interactions EXP 6480464 acadesine inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein], acadesine inhibits the reaction [glycidamide results in increased expression of CYP2E1 protein] CTD PMID:33545342 acarbose decreases expression EXP 6480464 Acarbose results in decreased expression of CYP2E1 mRNA CTD PMID:14975757 acephate multiple interactions ISO RGD:10451 6480464 [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein more ... CTD PMID:17686559 acetaldehyde increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Acetaldehyde CTD PMID:10826103 acetaldehyde multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Acetaldehyde CTD PMID:18845238 acetaldehyde multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde, phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] CTD PMID:7562599 acetamide increases expression EXP 6480464 acetamide results in increased expression of CYP2E1 mRNA CTD PMID:31881176 acetic acid increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Acetic Acid analog CTD PMID:21933969 acetone multiple interactions ISO RGD:10451 6480464 [Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene more ... CTD PMID:18990727 more ... acetone increases expression EXP 6480464 Acetone results in increased expression of CYP2E1 mRNA, Acetone results in increased expression of CYP2E1 protein CTD PMID:11939710 more ... acetone increases activity EXP 6480464 Acetone results in increased activity of CYP2E1 protein CTD PMID:12919724 more ... acetone increases expression ISO RGD:10451 6480464 Acetone results in increased expression of CYP2E1 mRNA, Acetone results in increased expression of CYP2E1 protein CTD PMID:18990727 , PMID:22499231 acetone multiple interactions EXP 6480464 1 more ... CTD PMID:7587954 more ... acetone increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Acetone CTD PMID:15576447 acetonitrile multiple interactions EXP 6480464 acetonitrile inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 acetonitrile multiple interactions ISO RGD:1345007 6480464 acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of CYP2E1 mRNA CTD PMID:11752103 acrylamide affects expression ISO RGD:1345007 6480464 Acrylamide affects the expression of CYP2E1 mRNA CTD PMID:17267090 acrylamide multiple interactions EXP 6480464 acadesine inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein] CTD PMID:33545342 acrylamide affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 intron polymorphism affects the metabolism of Acrylamide CTD PMID:29748789 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of CYP2E1 mRNA, Acrylamide results in increased expression of CYP2E1 protein CTD PMID:28606764 , PMID:33545342 acrylamide affects expression EXP 6480464 Acrylamide affects the expression of CYP2E1 mRNA CTD PMID:28959563 acrylamide increases expression ISO RGD:1345007 6480464 Acrylamide results in increased expression of CYP2E1 mRNA, Acrylamide results in increased expression of CYP2E1 protein CTD PMID:24508477 , PMID:32763439 acrylamide affects response to substance ISO RGD:1345007 6480464 CYP2E1 protein affects the susceptibility to Acrylamide CTD PMID:24508477 acrylamide multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased oxidation of Acrylamide] which results in increased abundance of glycidamide CTD PMID:27174446 acrylamide multiple interactions ISO RGD:1345007 6480464 [CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Acrylamide more ... CTD PMID:19131562 , PMID:24508477 acrylamide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Acrylamide CTD PMID:15355880 , PMID:17267090 acrylamide increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of Acrylamide CTD PMID:15355880 acrylamide affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of Acrylamide CTD PMID:17979661 acrylonitrile multiple interactions EXP 6480464 Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26332274 , PMID:9010585 acrylonitrile multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of Acrylonitrile] which results in increased chemical synthesis of 2-cyanoethylene oxide, CYP2E1 gene mutant form inhibits the reaction [Acrylonitrile results in increased mutagenesis of HPRT gene] CTD PMID:32529832 acrylonitrile increases expression EXP 6480464 Acrylonitrile results in increased expression of CYP2E1 mRNA CTD PMID:26332274 acrylonitrile increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Acrylonitrile CTD PMID:32529832 acrylonitrile increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Acrylonitrile CTD PMID:1664256 acrylonitrile affects response to substance EXP 6480464 CYP2E1 protein affects the susceptibility to Acrylonitrile CTD PMID:20127315 acteoside multiple interactions EXP 6480464 acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:14672760 aflatoxin B1 affects expression ISO RGD:1345007 6480464 Aflatoxin B1 affects the expression of CYP2E1 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:1345007 6480464 Aflatoxin B1 results in decreased expression of CYP2E1 mRNA CTD PMID:22100608 , PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CYP2E1 mRNA CTD PMID:23630614 aflatoxin B1 decreases expression ISO RGD:10451 6480464 Aflatoxin B1 results in decreased expression of CYP2E1 mRNA CTD PMID:19770486 alcohol increases activity ISO RGD:1345007 6480464 Alcohols results in increased activity of CYP2E1 protein CTD PMID:24025710 alcohol increases expression ISO RGD:10451 6480464 Alcohols results in increased expression of CYP2E1 protein CTD PMID:28803762 alcohol multiple interactions ISO RGD:10451 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein], Glutathione inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein] CTD PMID:28803762 alcohol increases expression ISO RGD:1345007 6480464 Alcohols results in increased expression of CYP2E1 mRNA CTD PMID:24025710 alcohol multiple interactions ISO RGD:1345007 6480464 Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA], ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA] CTD PMID:24025710 aldehydo-D-glucose increases expression ISO RGD:10451 6480464 Glucose results in increased expression of CYP2E1 mRNA CTD PMID:33448797 aldehydo-D-glucose multiple interactions ISO RGD:10451 6480464 fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 alizarin decreases activity ISO RGD:1345007 6480464 alizarin results in decreased activity of CYP2E1 protein CTD PMID:12379470 alkaloid multiple interactions EXP 6480464 Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA], Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein] CTD PMID:21224420 all-trans-retinoic acid multiple interactions ISO RGD:1345007 6480464 Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] CTD PMID:8531136 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of CYP2E1 mRNA CTD PMID:24977338 allethrin multiple interactions EXP 6480464 Allethrins results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:22080754 allyl alcohol increases expression ISO RGD:10451 6480464 allyl alcohol results in increased expression of CYP2E1 protein CTD PMID:11515535 allyl cyanide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to allyl cyanide CTD PMID:22051853 allyl cyanide multiple interactions ISO RGD:10451 6480464 [Acetone results in increased expression of CYP2E1 protein] which results in increased susceptibility to allyl cyanide CTD PMID:18990727 alpha-hexachlorocyclohexane multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein CTD PMID:16246485 alpha-linolenic acid decreases activity ISO RGD:1345007 6480464 alpha-Linolenic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 alpha-methyltryptamine multiple interactions ISO RGD:1345007 6480464 [indopan analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone, [indopan results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 alpha-methyltryptamine decreases activity ISO RGD:1345007 6480464 indopan analog results in decreased activity of CYP2E1 protein, indopan results in decreased activity of CYP2E1 protein CTD PMID:26599973 amiodarone decreases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 amitraz increases expression EXP 6480464 amitraz results in increased expression of CYP2E1 protein CTD PMID:31029719 amitrole decreases activity ISO RGD:1345007 6480464 Amitrole results in decreased activity of CYP2E1 protein CTD PMID:12464242 amlexanox multiple interactions ISO RGD:10451 6480464 amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 mRNA], amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 protein] CTD PMID:32905826 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CYP2E1 mRNA CTD PMID:16483693 amodiaquine multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine CTD PMID:31629065 amodiaquine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Amodiaquine CTD PMID:31629065 amphibole asbestos affects expression ISO RGD:1345007 6480464 Asbestos, Amphibole affects the expression of CYP2E1 protein CTD PMID:20855422 ampicillin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 angelicin decreases expression ISO RGD:10451 6480464 angelicin results in decreased expression of CYP2E1 protein CTD PMID:22173200 aniline increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of aniline CTD PMID:23274713 aniline increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of aniline CTD PMID:26463279 aniline increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of aniline CTD PMID:18038910 more ... aniline multiple interactions ISO RGD:10451 6480464 caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] more ... CTD PMID:18038910 more ... aniline increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of aniline CTD PMID:12464242 , PMID:8819299 aniline multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of [norharman co-treated with aniline] more ... CTD PMID:15279827 more ... aniline increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of aniline CTD PMID:8858968 , PMID:9195021 aniline decreases activity ISO RGD:1345007 6480464 aniline results in decreased activity of CYP2E1 protein CTD PMID:12814958 , PMID:15306208 aniline multiple interactions EXP 6480464 [Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of aniline more ... CTD PMID:11330834 more ... anthocyanin increases expression EXP 6480464 Anthocyanins results in increased expression of CYP2E1 mRNA CTD PMID:18803703 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1345007 6480464 pyrazolanthrone inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]], pyrazolanthrone inhibits the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA] CTD PMID:22486562 apigenin multiple interactions ISO RGD:10451 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein] CTD PMID:28803762 apigenin decreases activity ISO RGD:1345007 6480464 Apigenin results in decreased activity of CYP2E1 protein CTD PMID:29753067 arachidonic acid multiple interactions ISO RGD:1345007 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]] more ... CTD PMID:12086689 more ... arachidonic acid decreases activity ISO RGD:1345007 6480464 Arachidonic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 arachidonic acid affects hydroxylation EXP 6480464 CYP2E1 protein affects the hydroxylation of Arachidonic Acid CTD PMID:15205388 arachidonic acid increases response to substance ISO RGD:1345007 6480464 CYP2E1 results in increased susceptibility to Arachidonic Acid CTD PMID:12566070 arecoline increases activity EXP 6480464 Arecoline analog results in increased activity of CYP2E1 protein CTD PMID:25056785 Aroclor 1254 decreases expression ISO RGD:1345007 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA CTD PMID:17851650 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA, Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 protein CTD PMID:3113478 , PMID:8471063 arsane decreases activity EXP 6480464 Arsenic results in decreased activity of CYP2E1 protein CTD PMID:19932728 arsane multiple interactions EXP 6480464 Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:19932728 arsane affects expression ISO RGD:1345007 6480464 Arsenic affects the expression of CYP2E1 mRNA CTD PMID:18414638 arsenic atom affects expression ISO RGD:1345007 6480464 Arsenic affects the expression of CYP2E1 mRNA CTD PMID:18414638 arsenic atom decreases activity EXP 6480464 Arsenic results in decreased activity of CYP2E1 protein CTD PMID:19932728 arsenic atom multiple interactions EXP 6480464 Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:19932728 arsenous acid affects expression ISO RGD:1345007 6480464 Arsenic Trioxide affects the expression of CYP2E1 mRNA CTD PMID:17530438 asiatic acid multiple interactions EXP 6480464 asiatic acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased activity of CYP2E1 protein] CTD PMID:29108773 aspartame multiple interactions EXP 6480464 Aspartame results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:16937917 atrazine multiple interactions ISO RGD:10451 6480464 lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA] CTD PMID:26775023 atrazine increases expression ISO RGD:10451 6480464 Atrazine results in increased expression of CYP2E1 mRNA CTD PMID:26775023 baicalein decreases activity ISO RGD:1345007 6480464 baicalein results in decreased activity of CYP2E1 protein CTD PMID:29753067 benzene decreases activity ISO RGD:10451 6480464 Benzene results in decreased activity of CYP2E1 protein CTD PMID:8751834 benzene decreases methylation ISO RGD:1345007 6480464 Benzene results in decreased methylation of CYP2E1 promoter CTD PMID:28823944 benzene multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol more ... CTD PMID:15051535 benzene affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Benzene CTD PMID:15051535 , PMID:15226677 benzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Benzene CTD PMID:9118895 benzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Benzene CTD PMID:1739413 more ... benzene affects response to substance EXP 6480464 CYP2E1 protein affects the susceptibility to Benzene CTD PMID:9118891 benzene increases expression EXP 6480464 Benzene results in increased expression of CYP2E1 mRNA, Benzene results in increased expression of CYP2E1 protein CTD PMID:12919724 more ... benzene increases activity EXP 6480464 Benzene results in increased activity of CYP2E1 protein CTD PMID:12919724 more ... benzene affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to Benzene CTD PMID:8560479 benzene increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Benzene CTD PMID:8917693 benzene increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein alternative form results in increased hydroxylation of Benzene, CYP2E1 protein results in increased hydroxylation of Benzene CTD PMID:15122651 , PMID:20033806 benzene increases expression ISO RGD:1345007 6480464 Benzene results in increased expression of CYP2E1 mRNA CTD PMID:18952161 benzene affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to Benzene more ... CTD PMID:12460800 more ... benzene decreases expression EXP 6480464 Benzene results in decreased expression of CYP2E1 protein CTD PMID:15274493 benzene affects expression EXP 6480464 Benzene affects the expression of CYP2E1 mRNA CTD PMID:15878777 benzene decreases activity EXP 6480464 Benzene results in decreased activity of CYP2E1 protein CTD PMID:18407866 benzene increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of Benzene CTD PMID:11718959 , PMID:14718178 benzene increases expression ISO RGD:10451 6480464 Benzene results in increased expression of CYP2E1 mRNA, Benzene results in increased expression of CYP2E1 protein CTD PMID:12388843 more ... benzene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Benzene CTD PMID:17885617 more ... benzene increases response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Benzene CTD PMID:15226677 benzene multiple interactions ISO RGD:10451 6480464 [Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene more ... CTD PMID:12388843 more ... benzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Benzene CTD PMID:10207612 more ... benzene multiple interactions EXP 6480464 [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene more ... CTD PMID:18407866 more ... benzene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Benzene CTD PMID:11376689 , PMID:8461037 benzene increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of Benzene CTD PMID:8560479 benzene-1,2,4-triol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone CTD PMID:15051535 benzo[a]pyrene increases mutagenesis ISO RGD:1345007 6480464 Benzo(a)pyrene results in increased mutagenesis of CYP2E1 gene CTD PMID:25435355 benzo[a]pyrene increases expression ISO RGD:10451 6480464 Benzo(a)pyrene results in increased expression of CYP2E1 protein CTD PMID:34472326 benzo[a]pyrene decreases expression ISO RGD:1345007 6480464 Benzo(a)pyrene results in decreased expression of CYP2E1 mRNA CTD PMID:32234424 benzo[a]pyrene increases methylation ISO RGD:1345007 6480464 Benzo(a)pyrene results in increased methylation of CYP2E1 5' UTR CTD PMID:27901495 benzo[a]pyrene affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene SNP affects the susceptibility to Benzo(a)pyrene CTD PMID:28807506 benzo[a]pyrene affects methylation ISO RGD:1345007 6480464 Benzo(a)pyrene affects the methylation of CYP2E1 exon, Benzo(a)pyrene affects the methylation of CYP2E1 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1345007 6480464 Benzo(a)pyrene results in increased expression of CYP2E1 mRNA CTD PMID:16269432 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CYP2E1 mRNA, Benzo(a)pyrene results in increased expression of CYP2E1 protein CTD PMID:19889059 , PMID:21383588 benzo[a]pyrene decreases expression ISO RGD:10451 6480464 Benzo(a)pyrene results in decreased expression of CYP2E1 mRNA CTD PMID:19770486 , PMID:20127859 benzo[b]fluoranthene increases expression ISO RGD:1345007 6480464 benzo(b)fluoranthene results in increased expression of CYP2E1 mRNA CTD PMID:16269432 benzylideneacetone increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of benzylideneacetone CTD PMID:15863696 berberine decreases expression ISO RGD:10451 6480464 Berberine results in decreased expression of CYP2E1 mRNA CTD PMID:22342832 berberine multiple interactions ISO RGD:10451 6480464 Berberine inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein], Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA] CTD PMID:22342832 , PMID:25455889 Besigomsin multiple interactions ISO RGD:10451 6480464 schizandrol B inhibits the reaction [CYP2E1 protein results in increased metabolism of and results in increased activity of Acetaminophen] CTD PMID:25319358 Besigomsin decreases activity ISO RGD:10451 6480464 schizandrol B results in decreased activity of CYP2E1 protein CTD PMID:25319358 Besigomsin affects binding ISO RGD:10451 6480464 schizandrol B binds to CYP2E1 protein CTD PMID:25319358 beta-carboline multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of [norharman co-treated with aniline] CTD PMID:15279827 beta-naphthoflavone decreases expression ISO RGD:1345007 6480464 beta-Naphthoflavone results in decreased expression of CYP2E1 mRNA CTD PMID:22258563 beta-naphthoflavone multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with beta-Naphthoflavone] results in increased expression of KLF6 protein CTD PMID:22486562 beta-naphthoflavone increases expression ISO RGD:1345007 6480464 beta-Naphthoflavone results in increased expression of CYP2E1 mRNA, beta-Naphthoflavone results in increased expression of CYP2E1 protein CTD PMID:30373287 beta-naphthoflavone multiple interactions EXP 6480464 [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2E1 protein CTD PMID:30842367 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of CYP2E1 mRNA CTD PMID:19969063 bifenthrin increases expression ISO RGD:10451 6480464 bifenthrin results in increased expression of CYP2E1 mRNA CTD PMID:26071804 bilobalide increases activity EXP 6480464 bilobalide results in increased activity of CYP2E1 protein CTD PMID:18421621 biotin multiple interactions ISO RGD:1345007 6480464 Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 biphenyl-4-amine increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of 4-biphenylamine CTD PMID:25601990 biphenyl-4-amine increases expression ISO RGD:1345007 6480464 4-biphenylamine results in increased expression of CYP2E1 protein CTD PMID:33847444 biphenyl-4-amine multiple interactions ISO RGD:1345007 6480464 [Propolis co-treated with allyl sulfide] inhibits the reaction [4-biphenylamine results in increased expression of CYP2E1 protein] more ... CTD PMID:33847444 biphenyl-4-amine multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species CTD PMID:25601990 biphenyl-4-amine decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to 4-biphenylamine CTD PMID:25601990 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1345007 6480464 Diethylhexyl Phthalate results in decreased expression of CYP2E1 mRNA CTD PMID:31163220 bisphenol A increases glutathionylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased glutathionylation of bisphenol A metabolite CTD PMID:23470418 bisphenol A decreases expression ISO RGD:10451 6480464 bisphenol A results in decreased expression of CYP2E1 mRNA CTD PMID:33221593 bisphenol A increases expression ISO RGD:10451 6480464 bisphenol A results in increased expression of CYP2E1 mRNA CTD PMID:30245210 bisphenol A multiple interactions ISO RGD:10451 6480464 [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA CTD PMID:28123100 bisphenol A increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to bisphenol A CTD PMID:27491884 bisphenol A increases methylation ISO RGD:10451 6480464 bisphenol A results in increased methylation of CYP2E1 promoter CTD PMID:27312807 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CYP2E1 mRNA CTD PMID:25181051 , PMID:30903817 bisphenol A increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of bisphenol A, CYP2E1 protein results in increased hydroxylation of bisphenol A metabolite CTD PMID:23470418 bisphenol F increases glutathionylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased glutathionylation of 4, 4'-bisphenol F metabolite CTD PMID:23470418 bisphenol F increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of 4, 4'-bisphenol F CTD PMID:23470418 Bromadiolone increases expression EXP 6480464 bromadiolone results in increased expression of CYP2E1 mRNA CTD PMID:18080289 Bromadiolone decreases response to substance EXP 6480464 CYP2E1 protein results in decreased susceptibility to bromadiolone CTD PMID:18080289 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of CYP2E1 mRNA CTD PMID:12628495 bromodichloromethane increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of bromodichloromethane CTD PMID:12076521 more ... bromodichloromethane multiple interactions ISO RGD:10451 6480464 [Dietary Fats co-treated with bromodichloromethane] results in increased expression of CYP2E1 protein more ... CTD PMID:23438451 , PMID:24211274 bromodichloromethane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of bromodichloromethane CTD PMID:11295256 , PMID:12076521 bromodichloromethane increases expression EXP 6480464 bromodichloromethane results in increased expression of CYP2E1 protein CTD PMID:11295256 bromodichloromethane multiple interactions EXP 6480464 CYP2E1 protein results in increased metabolism of and results in increased activity of bromodichloromethane CTD PMID:9458004 bromodichloromethane decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to bromodichloromethane CTD PMID:23640861 bromoethene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of vinyl bromide CTD PMID:1664256 brucine multiple interactions EXP 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein, [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein CTD PMID:21800547 brucine increases activity EXP 6480464 brucine results in increased activity of CYP2E1 protein CTD PMID:21800547 bucladesine multiple interactions ISO RGD:1345007 6480464 Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] CTD PMID:8531136 buta-1,3-diene multiple interactions ISO RGD:10451 6480464 1 more ... CTD PMID:10828257 buta-1,3-diene increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of 1, 3-butadiene CTD PMID:10828257 buta-1,3-diene affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of 1, 3-butadiene CTD PMID:15470755 butan-2-one affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene mutant form affects the susceptibility to methylethyl ketone CTD PMID:21352904 butane-1,3-diol increases activity EXP 6480464 1, 3-butylene glycol results in increased activity of CYP2E1 protein CTD PMID:2919394 butane-1,3-diol increases expression EXP 6480464 1, 3-butylene glycol results in increased expression of CYP2E1 protein CTD PMID:2919394 Butylbenzyl phthalate decreases activity EXP 6480464 butylbenzyl phthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 Butylparaben decreases activity EXP 6480464 butylparaben results in decreased activity of CYP2E1 protein CTD PMID:27432241 C.I. Natural Red 20 decreases activity ISO RGD:1345007 6480464 shikonin results in decreased activity of CYP2E1 protein CTD PMID:28941798 C.I. Natural Red 20 decreases activity EXP 6480464 shikonin results in decreased activity of CYP2E1 protein CTD PMID:28941798 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of CYP2E1 mRNA CTD PMID:19167457 cadmium atom increases expression ISO RGD:1345007 6480464 Cadmium results in increased expression of CYP2E1 mRNA CTD PMID:21120746 cadmium dichloride decreases expression ISO RGD:10451 6480464 Cadmium Chloride results in decreased expression of CYP2E1 mRNA CTD PMID:11958953 cadmium dichloride multiple interactions ISO RGD:1345007 6480464 Cadmium Chloride affects the reaction [CYP2E1 protein results in increased susceptibility to Arachidonic Acid] CTD PMID:12566070 cafestol decreases activity ISO RGD:10451 6480464 cafestol results in decreased activity of CYP2E1 protein CTD PMID:17590492 caffeine affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Caffeine CTD PMID:1302044 , PMID:14586387 calcium atom affects expression EXP 6480464 Calcium affects the expression of CYP2E1 mRNA CTD PMID:15913539 calcium atom decreases uptake ISO RGD:1345007 6480464 CYP2E1 protein results in decreased uptake of Calcium CTD PMID:19028543 calcium(0) affects expression EXP 6480464 Calcium affects the expression of CYP2E1 mRNA CTD PMID:15913539 calcium(0) decreases uptake ISO RGD:1345007 6480464 CYP2E1 protein results in decreased uptake of Calcium CTD PMID:19028543 canadine increases expression ISO RGD:10451 6480464 canadine results in increased expression of CYP2E1 mRNA, canadine results in increased expression of CYP2E1 protein CTD PMID:28257954 cannabidiol increases expression ISO RGD:10451 6480464 Cannabidiol results in increased expression of CYP2E1 mRNA CTD PMID:31052254 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of CYP2E1 CTD PMID:22375877 carbamazepine decreases expression EXP 6480464 Carbamazepine results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 carbaryl decreases activity ISO RGD:1345007 6480464 Carbaryl results in decreased activity of CYP2E1 protein CTD PMID:22634058 carbaryl multiple interactions ISO RGD:1345007 6480464 Carbaryl inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 carbon monoxide decreases activity ISO RGD:1345007 6480464 Carbon Monoxide results in decreased activity of CYP2E1 protein CTD PMID:15036350 carbon monoxide multiple interactions EXP 6480464 Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)] CTD PMID:1903091 carbon nanotube decreases expression ISO RGD:10451 6480464 Nanotubes more ... CTD PMID:25554681 carnosine multiple interactions ISO RGD:10451 6480464 Carnosine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:19799668 catechol multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol, EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol] CTD PMID:8211999 catechol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol CTD PMID:15051535 CGP 52608 multiple interactions ISO RGD:1345007 6480464 CGP 52608 promotes the reaction [RORA protein binds to CYP2E1 gene] CTD PMID:28238834 chenodeoxycholic acid decreases expression ISO RGD:1345007 6480464 Chenodeoxycholic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:27174168 CHIR 99021 increases expression ISO RGD:1345007 6480464 Chir 99021 results in increased expression of CYP2E1 mRNA CTD PMID:26259606 CHIR 99021 multiple interactions ISO RGD:1345007 6480464 Chir 99021 results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:26259606 chloral hydrate multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Trichloroethylene] which results in increased chemical synthesis of Chloral Hydrate CTD PMID:1739413 chloral hydrate increases chemical synthesis EXP 6480464 CYP2E1 protein results in increased chemical synthesis of Chloral Hydrate CTD PMID:1739413 chlordecone increases expression ISO RGD:10451 6480464 Chlordecone results in increased expression of CYP2E1 mRNA CTD PMID:33711761 chlorfluazuron decreases activity ISO RGD:1345007 6480464 chlorfluazuron results in decreased activity of CYP2E1 protein CTD PMID:22634058 chlorfluazuron multiple interactions ISO RGD:1345007 6480464 chlorfluazuron inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 chlorobenzene multiple interactions ISO RGD:1345007 6480464 dihydroxyethyldithiocarbamate inhibits the reaction [CYP2E1 protein results in increased metabolism of chlorobenzene] CTD PMID:9817075 chlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of chlorobenzene CTD PMID:9817075 chlorobenzene multiple interactions EXP 6480464 [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene more ... CTD PMID:9010585 , PMID:9817075 chlorobenzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of chlorobenzene CTD PMID:9817075 chloroethene multiple interactions ISO RGD:1345007 6480464 CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene] more ... CTD PMID:12010862 more ... chloroethene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Vinyl Chloride CTD PMID:1664256 chloroethene affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:20134343 chloroethene increases activity EXP 6480464 Vinyl Chloride results in increased activity of CYP2E1 protein CTD PMID:15211785 , PMID:17710613 chloroethene multiple interactions EXP 6480464 1, 2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride] CTD PMID:7871537 chloroethene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Vinyl Chloride CTD PMID:17710613 , PMID:7871537 chloroethene increases activity ISO RGD:1345007 6480464 Vinyl Chloride results in increased activity of CYP2E1 protein CTD PMID:17710613 chloroethene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Vinyl Chloride CTD PMID:18350910 chloroethene affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Vinyl Chloride CTD PMID:17710613 chloroethene increases response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Vinyl Chloride, CYP2E1 gene SNP results in increased susceptibility to Vinyl Chloride CTD PMID:16270392 more ... chloroform increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Chloroform CTD PMID:18350910 chloroform increases response to substance ISO RGD:1345007 6480464 CYP2E1 gene SNP results in increased susceptibility to Chloroform CTD PMID:15289170 chloroform increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Chloroform CTD PMID:1664256 chlorogenic acid multiple interactions ISO RGD:10451 6480464 Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] CTD PMID:25043994 chloromethane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Methyl Chloride CTD PMID:1664256 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of CYP2E1 mRNA CTD PMID:23125180 chlorpromazine decreases activity ISO RGD:1345007 6480464 Chlorpromazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 chlorpromazine decreases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 chlorpyrifos decreases activity ISO RGD:1345007 6480464 Chlorpyrifos results in decreased activity of CYP2E1 protein CTD PMID:22634058 chlorpyrifos multiple interactions ISO RGD:1345007 6480464 Chlorpyrifos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 chlorzoxazone affects hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein affects the hydroxylation of Chlorzoxazone CTD PMID:7747284 chlorzoxazone increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Chlorzoxazone CTD PMID:25956474 more ... chlorzoxazone multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased abundance of 6-hydroxychlorzoxazone more ... CTD PMID:25956474 more ... chlorzoxazone increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Chlorzoxazone CTD PMID:28438436 chlorzoxazone increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:12433797 more ... chlorzoxazone increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 mRNA results in increased metabolism of Chlorzoxazone, CYP2E1 protein results in increased metabolism of Chlorzoxazone CTD PMID:12401345 more ... chlorzoxazone increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:10463382 chlorzoxazone increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:11911841 more ... chlorzoxazone affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Chlorzoxazone CTD PMID:12818727 more ... chlorzoxazone multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone more ... CTD PMID:21600194 , PMID:28438436 chlorzoxazone increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Chlorzoxazone CTD PMID:10207612 , PMID:21964418 chlorzoxazone affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Chlorzoxazone CTD PMID:15231049 , PMID:15879494 chlorzoxazone multiple interactions ISO RGD:1345007 6480464 [5-bromotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone more ... CTD PMID:11502731 more ... cholesterol decreases activity ISO RGD:10451 6480464 Cholesterol results in decreased activity of CYP2E1 protein CTD PMID:18420780 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein more ... CTD PMID:18798224 , PMID:26695085 choline multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] more ... CTD PMID:18952117 more ... chrysene increases expression ISO RGD:10451 6480464 chrysene results in increased expression of CYP2E1 mRNA CTD PMID:26377693 ciguatoxin CTX1B affects expression ISO RGD:10451 6480464 Ciguatoxins affects the expression of CYP2E1 mRNA CTD PMID:18353800 cimetidine multiple interactions ISO RGD:1345007 6480464 [Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein CTD PMID:22733800 cimetidine decreases expression ISO RGD:1345007 6480464 Cimetidine results in decreased expression of CYP2E1 protein CTD PMID:22733800 ciprofibrate multiple interactions EXP 6480464 [Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein more ... CTD PMID:7587954 ciprofibrate increases expression EXP 6480464 ciprofibrate results in increased expression of CYP2E1 mRNA CTD PMID:7587954 cis-caffeic acid multiple interactions EXP 6480464 caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 cisplatin increases expression ISO RGD:10451 6480464 Cisplatin results in increased expression of CYP2E1 protein CTD PMID:23770416 , PMID:25043994 cisplatin increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Cisplatin CTD PMID:20809784 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of CYP2E1 mRNA CTD PMID:22023808 cisplatin multiple interactions ISO RGD:10451 6480464 Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] more ... CTD PMID:21616140 more ... cisplatin multiple interactions EXP 6480464 turmeric extract affects the reaction [Cisplatin results in decreased activity of CYP2E1 protein] CTD PMID:24882083 cisplatin decreases activity EXP 6480464 Cisplatin results in decreased activity of CYP2E1 protein CTD PMID:24882083 citral multiple interactions ISO RGD:1345007 6480464 [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral, [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite CTD PMID:18824010 clofibrate multiple interactions ISO RGD:10451 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA] CTD PMID:17585979 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of CYP2E1 mRNA, Clofibrate results in increased expression of CYP2E1 protein CTD PMID:10476907 clothianidin decreases expression ISO RGD:1345007 6480464 clothianidin results in decreased expression of CYP2E1 mRNA CTD PMID:32201337 clothianidin multiple interactions ISO RGD:1345007 6480464 [clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:32201337 copper atom multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 copper atom decreases expression EXP 6480464 Copper results in decreased expression of CYP2E1 mRNA CTD PMID:22465980 copper(0) multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of CYP2E1 mRNA CTD PMID:22465980 corticosterone increases expression ISO RGD:1345007 6480464 Corticosterone results in increased expression of CYP2E1 mRNA, Corticosterone results in increased expression of CYP2E1 protein CTD PMID:35301062 corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of CYP2E1 mRNA, Corticosterone results in increased expression of CYP2E1 protein CTD PMID:35301062 corticosterone multiple interactions ISO RGD:1345007 6480464 Corticosterone promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA] CTD PMID:35301062 cortisol increases expression EXP 6480464 Hydrocortisone results in increased expression of CYP2E1 mRNA, Hydrocortisone results in increased expression of CYP2E1 protein CTD PMID:10476907 coumarin affects localization EXP 6480464 coumarin affects the localization of CYP2E1 protein CTD PMID:28803882 coumarin multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of coumarin] which results in increased abundance of 2-hydroxyphenylacetic acid CTD PMID:34334558 coumarin increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of coumarin CTD PMID:34334558 crocidolite asbestos decreases expression ISO RGD:10451 6480464 Asbestos, Crocidolite results in decreased expression of CYP2E1 mRNA CTD PMID:29279043 crocin-1 decreases activity EXP 6480464 crocin results in decreased activity of CYP2E1 protein CTD PMID:25899501 crocin-1 multiple interactions EXP 6480464 crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein] CTD PMID:25899501 curcumin affects expression EXP 6480464 Curcumin affects the expression of CYP2E1 protein CTD PMID:16805852 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] CTD PMID:33350580 curcumin multiple interactions ISO RGD:10451 6480464 Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] more ... CTD PMID:30423402 curcumin multiple interactions ISO RGD:1345007 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein] CTD PMID:24508477 curcumin increases expression EXP 6480464 Curcumin results in increased expression of CYP2E1 mRNA CTD PMID:18539377 cyanides multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides CTD PMID:15893539 cyanocob(III)alamin multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:20118189 cyclohexanols multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein CTD PMID:17393424 cycloheximide multiple interactions ISO RGD:1345007 6480464 (4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] more ... CTD PMID:8531136 , PMID:9143349 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein], Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein] CTD PMID:1968335 cycloheximide increases degradation ISO RGD:1345007 6480464 Cycloheximide results in increased degradation of CYP2E1 protein CTD PMID:9143349 cyclophosphamide increases metabolic processing EXP 6480464 CYP2E1 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 cyclosporin A decreases expression ISO RGD:1345007 6480464 Cyclosporine results in decreased expression of CYP2E1 mRNA CTD PMID:20106945 more ... cyclosporin A decreases expression ISO RGD:10451 6480464 Cyclosporine results in decreased expression of CYP2E1 mRNA CTD PMID:23830897 cyfluthrin increases activity EXP 6480464 cyfluthrin results in increased activity of CYP2E1 protein CTD PMID:23639246 cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of CYP2E1 mRNA CTD PMID:29727961 cylindrospermopsin decreases expression ISO RGD:10451 6480464 cylindrospermopsin results in decreased expression of CYP2E1 mRNA CTD PMID:20936652 cypermethrin decreases activity ISO RGD:10451 6480464 cypermethrin results in decreased activity of CYP2E1 protein CTD PMID:18420780 cypermethrin increases activity EXP 6480464 cypermethrin results in increased activity of CYP2E1 protein CTD PMID:25926273 cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein CTD PMID:25926273 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of CYP2E1 mRNA, cypermethrin results in increased expression of CYP2E1 protein CTD PMID:20815782 more ... cypermethrin multiple interactions ISO RGD:1345007 6480464 cypermethrin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 cypermethrin decreases activity ISO RGD:1345007 6480464 cypermethrin results in decreased activity of CYP2E1 protein CTD PMID:22634058 cyproconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of CYP2E1 mRNA CTD PMID:29038839 cyproconazole increases expression ISO RGD:1345007 6480464 cyproconazole results in increased expression of CYP2E1 protein CTD PMID:33150952 cyproconazole decreases expression ISO RGD:10451 6480464 cyproconazole results in decreased expression of CYP2E1 protein CTD PMID:33150952 cyproconazole decreases expression ISO RGD:1345007 6480464 cyproconazole results in decreased expression of CYP2E1 mRNA CTD PMID:29995386 D-glucose increases expression ISO RGD:10451 6480464 Glucose results in increased expression of CYP2E1 mRNA CTD PMID:33448797 D-glucose multiple interactions ISO RGD:10451 6480464 fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 D-penicillamine increases expression ISO RGD:1345007 6480464 Penicillamine results in increased expression of CYP2E1 mRNA CTD PMID:22843330 daidzein decreases activity ISO RGD:10451 6480464 daidzein results in decreased activity of CYP2E1 protein CTD PMID:18420780 daidzein decreases activity EXP 6480464 daidzein results in decreased activity of CYP2E1 protein CTD PMID:31870919 daidzein multiple interactions EXP 6480464 daidzein inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol] CTD PMID:31870919 deoxycholic acid multiple interactions EXP 6480464 Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein, Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:10453939 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 desipramine decreases activity ISO RGD:1345007 6480464 Desipramine results in decreased activity of CYP2E1 protein CTD PMID:15135088 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of CYP2E1 protein CTD PMID:11181506 dexamethasone multiple interactions EXP 6480464 2-amino-4-(3 more ... CTD PMID:20501703 dexamethasone increases expression ISO RGD:10451 6480464 Dexamethasone results in increased expression of CYP2E1 mRNA CTD PMID:21041162 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of CYP2E1 mRNA, Dexamethasone results in increased expression of CYP2E1 protein CTD PMID:14618091 more ... dextran sulfate decreases activity EXP 6480464 Dextran Sulfate results in decreased activity of CYP2E1 protein CTD PMID:28438436 dextran sulfate multiple interactions EXP 6480464 [Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazone CTD PMID:28438436 dextromethorphan decreases activity ISO RGD:10451 6480464 Dextromethorphan results in decreased activity of CYP2E1 protein CTD PMID:18420780 diallyl disulfide decreases expression ISO RGD:10451 6480464 diallyl disulfide results in decreased expression of CYP2E1 protein CTD PMID:10774820 diallyl disulfide multiple interactions ISO RGD:1345007 6480464 diallyl disulfide inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:19325051 diallyl disulfide decreases expression EXP 6480464 diallyl disulfide results in decreased expression of CYP2E1 protein CTD PMID:16000231 , PMID:24293383 diallyl disulfide decreases activity ISO RGD:1345007 6480464 diallyl disulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 diallyl disulfide multiple interactions ISO RGD:10451 6480464 [diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene, diallyl disulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:10774820 , PMID:35526736 Diallyl sulfide multiple interactions ISO RGD:1345007 6480464 [Propolis co-treated with allyl sulfide] inhibits the reaction [4-biphenylamine results in increased expression of CYP2E1 protein] more ... CTD PMID:12086689 more ... Diallyl sulfide decreases expression ISO RGD:10451 6480464 allyl sulfide results in decreased expression of CYP2E1 mRNA CTD PMID:33007364 Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of CYP2E1 protein CTD PMID:8627517 Diallyl sulfide increases activity EXP 6480464 allyl sulfide results in increased activity of CYP2E1 protein CTD PMID:15046820 Diallyl sulfide decreases activity EXP 6480464 allyl sulfide results in decreased activity of CYP2E1 protein CTD PMID:30247689 , PMID:7956723 Diallyl sulfide decreases expression EXP 6480464 allyl sulfide results in decreased expression of CYP2E1 protein CTD PMID:16000231 more ... Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1] more ... CTD PMID:20116195 more ... Diallyl sulfide multiple interactions ISO RGD:10451 6480464 allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA] more ... CTD PMID:21684301 more ... Diallyl sulfide decreases activity ISO RGD:1345007 6480464 allyl sulfide results in decreased activity of CYP2E1 protein CTD PMID:15974642 more ... diallyl trisulfide decreases expression EXP 6480464 diallyl trisulfide results in decreased expression of CYP2E1 protein CTD PMID:28115069 diallyl trisulfide multiple interactions EXP 6480464 diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:28115069 diarsenic trioxide affects expression ISO RGD:1345007 6480464 Arsenic Trioxide affects the expression of CYP2E1 mRNA CTD PMID:17530438 dibenz[a,h]anthracene increases expression ISO RGD:1345007 6480464 1 more ... CTD PMID:16269432 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] CTD PMID:26880746 dibenziodolium decreases activity EXP 6480464 diphenyleneiodonium results in decreased activity of CYP2E1 protein CTD PMID:26880746 dibutyl phthalate decreases activity EXP 6480464 Dibutyl Phthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 dichloromethane multiple interactions EXP 6480464 3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] more ... CTD PMID:8889796 dichloromethane multiple interactions ISO RGD:10451 6480464 [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in increased expression of CYP2E1 mRNA CTD PMID:29335169 dichloromethane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Methylene Chloride CTD PMID:1664256 dichloromethane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Methylene Chloride CTD PMID:8889796 diclofenac decreases activity ISO RGD:1345007 6480464 Diclofenac metabolite results in decreased activity of CYP2E1 protein CTD PMID:28960974 dicofol increases expression EXP 6480464 Dicofol results in increased expression of CYP2E1 protein CTD PMID:19595748 dicoumarol multiple interactions EXP 6480464 Dicumarol promotes the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 dicoumarol multiple interactions ISO RGD:1345007 6480464 Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Paraquat] results in increased expression of KLF6 protein], Dicumarol inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein] CTD PMID:22486562 diepoxybutane affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to diepoxybutane CTD PMID:15036125 diepoxybutane increases response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism results in increased susceptibility to diepoxybutane CTD PMID:17078101 diethyldithiocarbamic acid multiple interactions ISO RGD:10451 6480464 [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene, [Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene CTD PMID:12746132 , PMID:8560479 diethyldithiocarbamic acid multiple interactions ISO RGD:1345007 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of Lamotrigine] more ... CTD PMID:10215755 more ... diethyldithiocarbamic acid decreases activity ISO RGD:1345007 6480464 Ditiocarb results in decreased activity of CYP2E1 protein CTD PMID:15306208 more ... diethyldithiocarbamic acid decreases activity EXP 6480464 Ditiocarb results in decreased activity of CYP2E1 protein CTD PMID:1356728 diethyldithiocarbamic acid multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene] more ... CTD PMID:1538706 more ... diethylstilbestrol increases expression ISO RGD:10451 6480464 Diethylstilbestrol results in increased expression of CYP2E1 mRNA CTD PMID:21041162 dihydrocapsaicin increases expression EXP 6480464 dihydrocapsaicin results in increased expression of CYP2E1 CTD PMID:22375877 dihydroxyacetone decreases expression ISO RGD:1345007 6480464 Dihydroxyacetone results in decreased expression of CYP2E1 mRNA CTD PMID:32506039 dimethyl sulfoxide increases expression EXP 6480464 Dimethyl Sulfoxide results in increased expression of CYP2E1 protein CTD PMID:3113478 dimethyl sulfoxide increases activity ISO RGD:10451 6480464 Dimethyl Sulfoxide results in increased activity of CYP2E1 protein CTD PMID:17177172 dimethyl sulfoxide multiple interactions EXP 6480464 Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein more ... CTD PMID:1538706 more ... dimethyl sulfoxide increases expression ISO RGD:1345007 6480464 Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA, Dimethyl Sulfoxide results in increased expression of CYP2E1 protein CTD PMID:30262279 more ... dimethyl sulfoxide multiple interactions ISO RGD:1345007 6480464 Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein], Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] CTD PMID:12147272 , PMID:9143349 dimethyl sulfoxide affects expression ISO RGD:1345007 6480464 Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA CTD PMID:12843640 dimethylmercury decreases expression EXP 6480464 dimethyl mercury results in decreased expression of CYP2E1 protein CTD PMID:21424224 dimethylmercury multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] CTD PMID:21424224 dioscin multiple interactions ISO RGD:10451 6480464 dioscin inhibits the reaction [Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein], dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:22939915 , PMID:24146112 dioscin multiple interactions EXP 6480464 dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:24146112 diosmetin decreases activity ISO RGD:1345007 6480464 diosmetin results in decreased activity of CYP2E1 protein CTD PMID:28867436 diosmin multiple interactions EXP 6480464 Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein] CTD PMID:23665045 dioxygen decreases expression ISO RGD:1345007 6480464 Oxygen deficiency results in decreased expression of CYP2E1 mRNA CTD PMID:19695866 dioxygen increases expression ISO RGD:1345007 6480464 Oxygen deficiency results in increased expression of CYP2E1 mRNA CTD PMID:33811995 dioxygen multiple interactions ISO RGD:1345007 6480464 Oxygen deficiency inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] CTD PMID:33811995 dioxygen multiple interactions EXP 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA more ... CTD PMID:26747958 dipropyl disulfide decreases activity ISO RGD:1345007 6480464 n-propyl disulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 dipropyl phthalate decreases activity EXP 6480464 di-n-propylphthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 Dipropyl sulfide decreases activity ISO RGD:1345007 6480464 dipropyl sulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 diprotium oxide multiple interactions ISO RGD:10451 6480464 [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP2E1 mRNA CTD PMID:29335169 disulfiram multiple interactions ISO RGD:1345007 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene more ... CTD PMID:10805064 more ... disulfiram decreases activity ISO RGD:1345007 6480464 Disulfiram results in decreased activity of CYP2E1 protein CTD PMID:1664256 more ... disulfiram multiple interactions ISO RGD:10451 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene CTD PMID:20470765 disulfiram decreases expression EXP 6480464 Disulfiram results in decreased expression of CYP2E1 mRNA, Disulfiram results in decreased expression of CYP2E1 protein CTD PMID:9393675 disulfiram decreases activity EXP 6480464 Disulfiram results in decreased activity of CYP2E1 protein CTD PMID:9393675 disulfiram multiple interactions EXP 6480464 Disulfiram binds to and results in decreased activity of CYP2E1 protein CTD PMID:18754103 dodecanoic acid increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of lauric acid CTD PMID:12464242 dopamine decreases activity ISO RGD:10451 6480464 Dopamine results in decreased activity of CYP2E1 protein CTD PMID:18420780 doxorubicin increases expression ISO RGD:10451 6480464 Doxorubicin results in increased expression of CYP2E1 mRNA CTD PMID:26873546 dronedarone increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of dronedarone CTD PMID:29616291 ebselen multiple interactions EXP 6480464 ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:11903743 elemental selenium multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] CTD PMID:21424224 ellipticine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of ellipticine CTD PMID:22917556 emamectin benzoate multiple interactions ISO RGD:10451 6480464 Plant Oils inhibits the reaction [emamectin benzoate results in increased expression of CYP2E1 mRNA] CTD PMID:29268245 emamectin benzoate increases expression ISO RGD:10451 6480464 emamectin benzoate results in increased expression of CYP2E1 mRNA CTD PMID:29268245 endosulfan decreases expression ISO RGD:1345007 6480464 Endosulfan results in decreased expression of CYP2E1 mRNA, Endosulfan results in decreased expression of CYP2E1 protein CTD PMID:26159488 , PMID:28673560 endosulfan increases expression ISO RGD:10451 6480464 Endosulfan analog results in increased expression of CYP2E1 mRNA, Endosulfan results in increased expression of CYP2E1 mRNA CTD PMID:29702342 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of CYP2E1 mRNA CTD PMID:29391264 endosulfan multiple interactions ISO RGD:1345007 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:26159488 , PMID:28673560 enfuvirtide affects activity ISO RGD:1345007 6480464 enfuvirtide affects the activity of CYP2E1 protein CTD PMID:15656696 enilconazole decreases expression ISO RGD:1345007 6480464 enilconazole results in decreased expression of CYP2E1 mRNA CTD PMID:32201337 enilconazole multiple interactions ISO RGD:1345007 6480464 [clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:32201337 epoxiconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of CYP2E1 mRNA CTD PMID:29038839 erastin multiple interactions ISO RGD:1345007 6480464 erastin affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol] CTD PMID:33017621 Erionite decreases expression ISO RGD:10451 6480464 erionite results in decreased expression of CYP2E1 mRNA CTD PMID:29279043 Estragole increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of estragole CTD PMID:19920071 ethambutol decreases activity ISO RGD:1345007 6480464 Ethambutol results in decreased activity of CYP2E1 protein CTD PMID:24910189 ethambutol multiple interactions EXP 6480464 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein more ... CTD PMID:27919644 ethanol multiple interactions EXP 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA more ... CTD PMID:15763544 more ... ethanol increases stability ISO RGD:1345007 6480464 Ethanol results in increased stability of CYP2E1 protein CTD PMID:32199159 ethanol decreases activity EXP 6480464 Ethanol results in decreased activity of CYP2E1 protein CTD PMID:17299812 ethanol increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Ethanol CTD PMID:28131861 ethanol multiple interactions ISO RGD:1345007 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:10573527 more ... ethanol decreases expression ISO RGD:10451 6480464 Ethanol results in decreased expression of CYP2E1 mRNA CTD PMID:28119953 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CYP2E1 mRNA, Ethanol results in increased expression of CYP2E1 protein CTD PMID:19609968 more ... ethanol increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Ethanol CTD PMID:10573527 more ... ethanol affects activity ISO RGD:1345007 6480464 Ethanol affects the activity of CYP2E1 protein CTD PMID:22530035 ethanol increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of Ethanol CTD PMID:22552773 ethanol increases activity EXP 6480464 Ethanol results in increased activity of CYP2E1 protein CTD PMID:15998439 more ... ethanol increases expression ISO RGD:1345007 6480464 Ethanol results in increased expression of CYP2E1 more ... CTD PMID:17590308 more ... ethanol affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to Ethanol, CYP2E1 protein affects the susceptibility to Ethanol CTD PMID:20171022 , PMID:33017621 ethanol increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Ethanol CTD PMID:21130154 ethanol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Ethanol CTD PMID:11147839 more ... ethanol increases activity ISO RGD:1345007 6480464 Ethanol results in increased activity of CYP2E1 protein CTD PMID:11212141 , PMID:8074729 ethanol affects activity EXP 6480464 Ethanol affects the activity of CYP2E1 protein CTD PMID:17533807 ethanol increases activity ISO RGD:10451 6480464 Ethanol results in increased activity of CYP2E1 protein CTD PMID:10667633 , PMID:15920153 ethanol multiple interactions ISO RGD:10451 6480464 [AQP4 protein affects the susceptibility to Ethanol] which affects the expression of CYP2E1 mRNA more ... CTD PMID:15582191 more ... ethanol increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to Ethanol CTD PMID:8798623 ethanol increases expression ISO RGD:10451 6480464 Ethanol results in increased expression of CYP2E1 more ... CTD PMID:11515535 more ... ethene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of ethylene CTD PMID:21785163 ethene decreases activity EXP 6480464 ethylene results in decreased activity of CYP2E1 protein CTD PMID:15141094 ethene multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of ethylene] which results in increased abundance of Ethylene Oxide CTD PMID:21785163 ethosuximide affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Ethosuximide CTD PMID:1438522 ethyl methanesulfonate decreases expression ISO RGD:1345007 6480464 Ethyl Methanesulfonate results in decreased expression of CYP2E1 mRNA CTD PMID:23649840 ethylbenzene multiple interactions EXP 6480464 ethylbenzene results in increased expression of and results in increased activity of CYP2E1 protein, GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein] CTD PMID:11884239 ethylbenzene increases expression EXP 6480464 ethylbenzene results in increased expression of CYP2E1 mRNA, ethylbenzene results in increased expression of CYP2E1 protein CTD PMID:11884239 more ... ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:1345007 6480464 Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 ethylenediaminetetraacetic acid multiple interactions ISO RGD:1345007 6480464 Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 ethylparaben decreases activity EXP 6480464 ethyl-p-hydroxybenzoate results in decreased activity of CYP2E1 protein CTD PMID:27432241 eugenol multiple interactions EXP 6480464 Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein] CTD PMID:20036707 eugenol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 farnesol increases activity EXP 6480464 Farnesol results in increased activity of CYP2E1 protein CTD PMID:15840382 farnesol multiple interactions ISO RGD:1345007 6480464 [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA, Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA] CTD PMID:30611723 farnesol decreases expression ISO RGD:1345007 6480464 Farnesol analog results in decreased expression of CYP2E1 mRNA, Farnesol results in decreased expression of CYP2E1 mRNA CTD PMID:30611723 felbamate decreases expression EXP 6480464 felbamate results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 felbamate increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Felbamate CTD PMID:35786679 fenarimol multiple interactions ISO RGD:10451 6480464 [fenarimol co-treated with acephate] affects the expression of CYP2E1 protein more ... CTD PMID:17686559 fenitrothion multiple interactions ISO RGD:1345007 6480464 Fenitrothion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 fenitrothion decreases activity ISO RGD:1345007 6480464 Fenitrothion results in decreased activity of CYP2E1 protein CTD PMID:22634058 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of CYP2E1 mRNA CTD PMID:19118567 fenvalerate decreases activity ISO RGD:1345007 6480464 fenvalerate results in decreased activity of CYP2E1 protein CTD PMID:22634058 fenvalerate multiple interactions ISO RGD:1345007 6480464 fenvalerate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 ferrostatin-1 multiple interactions ISO RGD:1345007 6480464 ferrostatin-1 affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol], FXN protein affects the reaction [ferrostatin-1 affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol]] CTD PMID:33017621 fipronil increases expression EXP 6480464 fipronil results in increased expression of CYP2E1 mRNA CTD PMID:23962444 fipronil decreases expression ISO RGD:1345007 6480464 fipronil results in decreased expression of CYP2E1 mRNA CTD PMID:27091632 fipronil multiple interactions ISO RGD:1345007 6480464 [fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA CTD PMID:27091632 flavonoids multiple interactions ISO RGD:10451 6480464 Flavonoids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein] CTD PMID:23279844 fluoranthene increases expression ISO RGD:1345007 6480464 fluoranthene results in increased expression of CYP2E1 mRNA CTD PMID:16269432 fluoroethene multiple interactions ISO RGD:1345007 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride CTD PMID:9073601 fluoroethene multiple interactions EXP 6480464 [Ethanol results in increased activity of CYP2E1 protein] which results in increased metabolism of vinyl fluoride, [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride CTD PMID:9073601 fluoroethene multiple interactions ISO RGD:10451 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride CTD PMID:9073601 fluoroethene affects oxidation ISO RGD:10451 6480464 CYP2E1 protein affects the oxidation of vinyl fluoride CTD PMID:9073601 fluphenazine decreases activity ISO RGD:1345007 6480464 Fluphenazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 folic acid multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein], [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2E1 mRNA CTD PMID:20118189 , PMID:22872676 fomepizole multiple interactions ISO RGD:1345007 6480464 [Fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride more ... CTD PMID:11409937 more ... fomepizole decreases activity ISO RGD:1345007 6480464 Fomepizole results in decreased activity of CYP2E1 protein CTD PMID:21336516 more ... fomepizole increases expression EXP 6480464 fomepizole results in increased expression of CYP2E1 protein CTD PMID:3113478 , PMID:3782137 fomepizole increases activity EXP 6480464 fomepizole results in increased activity of CYP2E1 protein CTD PMID:3782137 fomepizole multiple interactions ISO RGD:10451 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride CTD PMID:9073601 fomepizole multiple interactions EXP 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride, fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide] CTD PMID:1538706 , PMID:9073601 fomepizole increases expression ISO RGD:1345007 6480464 fomepizole results in increased expression of CYP2E1 protein CTD PMID:8074729 fructose multiple interactions ISO RGD:10451 6480464 Ethanol promotes the reaction [Fructose results in increased expression of CYP2E1 protein] CTD PMID:26858005 fructose decreases expression ISO RGD:10451 6480464 Fructose results in decreased expression of CYP2E1 protein CTD PMID:28257781 fructose increases expression ISO RGD:10451 6480464 Fructose results in increased expression of CYP2E1 protein CTD PMID:26858005 fucoxanthin multiple interactions ISO RGD:10451 6480464 fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 fulvestrant multiple interactions ISO RGD:1345007 6480464 fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of CYP2E1 mRNA] CTD PMID:29362861 fumaraldehyde multiple interactions EXP 6480464 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde] more ... CTD PMID:21842885 fumonisin B1 decreases expression ISO RGD:10451 6480464 fumonisin B1 results in decreased expression of CYP2E1 mRNA CTD PMID:16221962 Furafylline decreases activity EXP 6480464 furafylline results in decreased activity of CYP2E1 protein CTD PMID:15879494 furan decreases expression EXP 6480464 furan results in decreased expression of CYP2E1 mRNA, furan results in decreased expression of CYP2E1 protein CTD PMID:15120968 , PMID:20124500 furan multiple interactions ISO RGD:10451 6480464 rhodioloside inhibits the reaction [furan results in increased expression of CYP2E1 protein] CTD PMID:34450210 furan increases expression ISO RGD:10451 6480464 furan results in increased expression of CYP2E1 protein CTD PMID:34450210 furan multiple interactions EXP 6480464 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde] more ... CTD PMID:21842885 gabapentin decreases expression EXP 6480464 gabapentin results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 gadolinium trichloride multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA], gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein] CTD PMID:18202523 gallocatechin multiple interactions ISO RGD:10451 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2E1 mRNA CTD PMID:25663641 gamma-hexachlorocyclohexane increases activity EXP 6480464 Hexachlorocyclohexane results in increased activity of CYP2E1 protein CTD PMID:12842176 , PMID:14631868 gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of CYP2E1 mRNA, Hexachlorocyclohexane results in increased expression of CYP2E1 protein CTD PMID:12842176 more ... gamma-hexachlorocyclohexane decreases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in decreased susceptibility to Hexachlorocyclohexane CTD PMID:21458603 gamma-hexachlorocyclohexane decreases expression ISO RGD:1345007 6480464 Hexachlorocyclohexane results in decreased expression of CYP2E1 mRNA CTD PMID:20035023 genistein multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of CYP2E1 mRNA more ... CTD PMID:21782745 , PMID:23274713 genistein multiple interactions ISO RGD:10451 6480464 Genistein inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:23333575 gentamycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 geranial multiple interactions ISO RGD:1345007 6480464 [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral, [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite CTD PMID:18824010 geraniol multiple interactions EXP 6480464 geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein] CTD PMID:26695085 geraniol multiple interactions ISO RGD:1345007 6480464 [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral more ... CTD PMID:18824010 ginsenoside Rg1 multiple interactions ISO RGD:10451 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:29964319 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of CYP2E1 mRNA CTD PMID:24136188 glucose multiple interactions ISO RGD:10451 6480464 fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 glucose increases expression ISO RGD:10451 6480464 Glucose results in increased expression of CYP2E1 mRNA CTD PMID:33448797 glutathione multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac more ... CTD PMID:10573527 more ... glutathione multiple interactions ISO RGD:10451 6480464 Glutathione inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein] CTD PMID:28803762 glutathione multiple interactions EXP 6480464 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde] more ... CTD PMID:21842885 , PMID:8211999 Glutathione ethyl ester multiple interactions ISO RGD:1345007 6480464 S-ethyl glutathione inhibits the reaction [[CYP2E1 protein co-treated with Paraquat] results in increased expression of KLF6 protein] more ... CTD PMID:16872732 , PMID:22486562 glycerol multiple interactions ISO RGD:1345007 6480464 Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 glycine betaine multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:20118189 glycine betaine multiple interactions ISO RGD:1345007 6480464 Betaine promotes the reaction [Ethanol results in increased expression of CYP2E1] CTD PMID:21352821 glycyrrhetinate multiple interactions EXP 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein CTD PMID:21800547 glycyrrhetinic acid multiple interactions EXP 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein CTD PMID:21800547 glyphosate increases methylation EXP 6480464 glyphosate results in increased methylation of CYP2E1 gene CTD PMID:31011160 GW 4064 multiple interactions ISO RGD:1345007 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA CTD PMID:30611723 GW 4064 decreases expression ISO RGD:1345007 6480464 GW 4064 results in decreased expression of CYP2E1 mRNA CTD PMID:30611723 halothane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Halothane CTD PMID:10805064 halothane affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Halothane CTD PMID:9103523 halothane increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Halothane CTD PMID:11684365 , PMID:12464242 halothane increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Halothane CTD PMID:12803597 halothane multiple interactions ISO RGD:1345007 6480464 Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane] CTD PMID:10805064 hemin multiple interactions EXP 6480464 Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26747958 hemin multiple interactions ISO RGD:1345007 6480464 Hemin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:19325051 hesperetin multiple interactions EXP 6480464 hesperetin inhibits the reaction [1, 2-Dimethylhydrazine results in increased activity of CYP2E1 protein] CTD PMID:19497424 hexachlorobenzene decreases expression EXP 6480464 Hexachlorobenzene results in decreased expression of CYP2E1 mRNA CTD PMID:15159207 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of CYP2E1 protein CTD PMID:10696772 hexadecanoic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26854922 hexadecanoic acid increases expression ISO RGD:10451 6480464 Palmitic Acid results in increased expression of CYP2E1 mRNA, Palmitic Acid results in increased expression of CYP2E1 protein CTD PMID:32905826 hexadecanoic acid multiple interactions ISO RGD:10451 6480464 amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 mRNA], amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 protein] CTD PMID:32905826 hexane affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to n-hexane CTD PMID:16484137 hexane multiple interactions EXP 6480464 diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein], n-hexane results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:28115069 hexane increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of n-hexane CTD PMID:11201664 hexane increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of n-hexane CTD PMID:16484137 hydrazine increases activity EXP 6480464 hydrazine results in increased activity of CYP2E1 protein CTD PMID:15132840 hydrogen peroxide increases abundance ISO RGD:1345007 6480464 CYP2E1 protein results in increased abundance of Hydrogen Peroxide CTD PMID:25061110 hydrogen peroxide multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with Hydrogen Peroxide co-treated with Arachidonic Acid] results in increased expression of KLF6 protein, [CYP2E1 protein co-treated with Hydrogen Peroxide] results in increased expression of KLF6 protein CTD PMID:22486562 hydroquinone multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone more ... CTD PMID:8211999 hydroquinone multiple interactions ISO RGD:10451 6480464 Resveratrol inhibits the reaction [hydroquinone results in increased expression of CYP2E1 mRNA] CTD PMID:23202692 hydroquinone increases expression ISO RGD:10451 6480464 hydroquinone results in increased expression of CYP2E1 mRNA CTD PMID:23202692 hydroquinone increases expression ISO RGD:1345007 6480464 hydroquinone results in increased expression of CYP2E1 mRNA, hydroquinone results in increased expression of CYP2E1 protein CTD PMID:30567741 hydroquinone multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone more ... CTD PMID:15051535 , PMID:30567741 Hypaconitine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of hypaconitine CTD PMID:21550385 imidazoles multiple interactions EXP 6480464 Imidazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 indole-3-methanol decreases activity ISO RGD:1345007 6480464 indole-3-carbinol results in decreased activity of CYP2E1 protein CTD PMID:17582584 indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of CYP2E1 mRNA CTD PMID:16771604 irbesartan multiple interactions ISO RGD:10451 6480464 Irbesartan inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:31967706 iron(III) citrate multiple interactions ISO RGD:1345007 6480464 Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA], ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA] CTD PMID:24025710 iron(III) citrate increases expression ISO RGD:1345007 6480464 ferric citrate results in increased expression of CYP2E1 mRNA CTD PMID:24025710 iron(III) nitrilotriacetate multiple interactions ISO RGD:1345007 6480464 [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein more ... CTD PMID:12086689 more ... isatin increases expression ISO RGD:1345007 6480464 Isatin results in increased expression of CYP2E1 mRNA CTD PMID:15056799 isobavachalcone multiple interactions EXP 6480464 isobavachalcone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol] CTD PMID:31870919 isobavachalcone decreases activity EXP 6480464 isobavachalcone results in decreased activity of CYP2E1 protein CTD PMID:31870919 isobutyronitrile increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to isobutyronitrile CTD PMID:22051853 isoliquiritigenin multiple interactions EXP 6480464 isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA], isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25450236 isoniazide affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to Isoniazid, CYP2E1 gene SNP affects the susceptibility to Isoniazid CTD PMID:12668988 , PMID:20485159 isoniazide multiple interactions ISO RGD:1345007 6480464 GSTM1 protein inhibits the reaction [CYP2E1 protein results in increased susceptibility to Isoniazid] CTD PMID:28762043 isoniazide increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to Isoniazid CTD PMID:28762043 isoniazide increases activity EXP 6480464 Isoniazid results in increased activity of CYP2E1 protein CTD PMID:12458634 more ... isoniazide multiple interactions ISO RGD:10451 6480464 Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA] CTD PMID:22342832 isoniazide increases expression ISO RGD:10451 6480464 Isoniazid results in increased expression of CYP2E1 mRNA CTD PMID:22342832 isoniazide increases expression EXP 6480464 Isoniazid results in increased expression of CYP2E1 more ... CTD PMID:11752103 more ... isoniazide increases expression ISO RGD:1345007 6480464 Isoniazid results in increased expression of CYP2E1 protein CTD PMID:8074729 isoniazide multiple interactions EXP 6480464 2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] more ... CTD PMID:12458634 more ... isoniazide increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Isoniazid CTD PMID:17950035 isoprenaline affects expression EXP 6480464 Isoproterenol affects the expression of CYP2E1 mRNA CTD PMID:18725507 isoproturon decreases activity ISO RGD:1345007 6480464 isoproturon results in decreased activity of CYP2E1 protein CTD PMID:22634058 isoproturon multiple interactions ISO RGD:1345007 6480464 isoproturon inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 isoquinolines multiple interactions EXP 6480464 Isoquinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 ivermectin decreases activity ISO RGD:10451 6480464 Ivermectin results in decreased activity of CYP2E1 protein CTD PMID:18420780 kaempferol multiple interactions ISO RGD:10451 6480464 kaempferol inhibits the reaction [propacetamol results in increased expression of CYP2E1 protein] CTD PMID:29574133 kahweol decreases activity ISO RGD:10451 6480464 kahweol results in decreased activity of CYP2E1 protein CTD PMID:17590492 ketamine increases expression EXP 6480464 Ketamine results in increased expression of CYP2E1 protein CTD PMID:16076768 ketoconazole decreases activity ISO RGD:1345007 6480464 Ketoconazole results in decreased activity of CYP2E1 protein CTD PMID:15618748 kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA CTD PMID:18544905 L-ascorbic acid multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein] more ... CTD PMID:31585129 , PMID:31739238 L-ascorbic acid decreases activity ISO RGD:1345007 6480464 Ascorbic Acid results in decreased activity of CYP2E1 protein CTD PMID:17512695 L-methionine multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] more ... CTD PMID:18952117 more ... L-methionine multiple interactions EXP 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] more ... CTD PMID:26695085 , PMID:27919644 lamotrigine increases glutathionylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased glutathionylation of lamotrigine CTD PMID:19961160 lamotrigine multiple interactions ISO RGD:1345007 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of lamotrigine] CTD PMID:19961160 Lasiocarpine decreases expression ISO RGD:1345007 6480464 lasiocarpine results in decreased expression of CYP2E1 mRNA CTD PMID:32234424 leupeptin multiple interactions ISO RGD:1345007 6480464 leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 Licochalcone A affects activity ISO RGD:1345007 6480464 licochalcone A affects the activity of CYP2E1 protein CTD PMID:26100226 linoleic acid decreases activity ISO RGD:1345007 6480464 Linoleic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 lipoic acid multiple interactions ISO RGD:10451 6480464 Thioctic Acid affects the reaction [cyanoginosin LR affects the expression of CYP2E1 protein] CTD PMID:32061150 lipopolysaccharide multiple interactions ISO RGD:1345007 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP2E1 mRNA, Lipopolysaccharides affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] CTD PMID:16235733 , PMID:22777745 lipopolysaccharide multiple interactions ISO RGD:10451 6480464 [AQP4 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of CYP2E1 mRNA CTD PMID:20615459 liquiritin multiple interactions EXP 6480464 [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein CTD PMID:21800547 lithocholic acid decreases activity ISO RGD:10451 6480464 Lithocholic Acid results in decreased activity of CYP2E1 protein CTD PMID:18420780 luteolin multiple interactions ISO RGD:10451 6480464 Luteolin inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] CTD PMID:23770416 LY294002 increases expression EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CYP2E1 mRNA CTD PMID:11306697 lycopene multiple interactions ISO RGD:10451 6480464 lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA] CTD PMID:26775023 m-tolualdehyde decreases activity EXP 6480464 3-methylbenzaldehyde results in decreased activity of CYP2E1 protein CTD PMID:12791539 m-xylene affects activity EXP 6480464 3-xylene affects the activity of CYP2E1 protein CTD PMID:15204773 , PMID:8598570 m-xylene multiple interactions ISO RGD:1345007 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene] CTD PMID:8558417 m-xylene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 3-xylene CTD PMID:17156750 m-xylene increases hydrolysis ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydrolysis of 3-xylene CTD PMID:10353308 m-xylene multiple interactions EXP 6480464 3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] CTD PMID:8889796 m-xylene decreases activity EXP 6480464 3-xylene results in decreased activity of CYP2E1 protein CTD PMID:12791539 m-xylene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 3-xylene CTD PMID:8558417 m-xylene increases activity EXP 6480464 3-xylene results in increased activity of CYP2E1 protein CTD PMID:8889796 m-xylene increases expression EXP 6480464 3-xylene results in increased expression of CYP2E1 protein CTD PMID:8517779 malathion decreases activity ISO RGD:1345007 6480464 Malathion results in decreased activity of CYP2E1 protein CTD PMID:22634058 malathion multiple interactions ISO RGD:1345007 6480464 Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 mancozeb decreases expression ISO RGD:1345007 6480464 mancozeb results in decreased expression of CYP2E1 mRNA CTD PMID:31096615 mandelic acid multiple interactions ISO RGD:1345007 6480464 CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 maneb decreases activity EXP 6480464 Maneb results in decreased activity of CYP2E1 protein CTD PMID:11043497 maneb increases expression EXP 6480464 Maneb results in increased expression of CYP2E1 mRNA, Maneb results in increased expression of CYP2E1 protein CTD PMID:20888808 , PMID:23159886 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein more ... CTD PMID:23159886 maneb increases activity EXP 6480464 Maneb results in increased activity of CYP2E1 protein CTD PMID:20888808 maneb multiple interactions ISO RGD:10451 6480464 [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA more ... CTD PMID:16510128 , PMID:20964710 mangiferin decreases activity EXP 6480464 mangiferin results in decreased activity of CYP2E1 protein CTD PMID:18053976 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Benzene results in increased activity of CYP2E1 protein] CTD PMID:20338863 melatonin multiple interactions ISO RGD:10451 6480464 Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein], Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA] CTD PMID:20964710 menadione decreases expression ISO RGD:10451 6480464 Vitamin K 3 results in decreased expression of CYP2E1 mRNA CTD PMID:25270620 menadione multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein more ... CTD PMID:22486562 mephenytoin decreases activity ISO RGD:10451 6480464 Mephenytoin results in decreased activity of CYP2E1 protein CTD PMID:18420780 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of CYP2E1 mRNA CTD PMID:22792809 metformin increases expression ISO RGD:10451 6480464 Metformin results in increased expression of CYP2E1 mRNA CTD PMID:22342832 methamphetamine affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 methapyrilene decreases expression ISO RGD:1345007 6480464 Methapyrilene results in decreased expression of CYP2E1 mRNA CTD PMID:28935588 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of CYP2E1 mRNA CTD PMID:30467583 methoxsalen decreases activity EXP 6480464 Methoxsalen results in decreased activity of CYP2E1 protein CTD PMID:15879494 methoxsalen decreases activity ISO RGD:10451 6480464 Methoxsalen results in decreased activity of CYP2E1 protein CTD PMID:18420780 methoxychlor multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of CYP2E1 mRNA, Methoxychlor results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:12919727 , PMID:21782745 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of CYP2E1 mRNA CTD PMID:21782745 methoxychlor decreases activity ISO RGD:10451 6480464 Methoxychlor results in decreased activity of CYP2E1 protein CTD PMID:18420780 methoxyflurane increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 methyltestosterone multiple interactions ISO RGD:1345007 6480464 [Methyltestosterone co-treated with Cholic Acids] affects the expression of CYP2E1 mRNA CTD PMID:27344345 metronidazole multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 microcystin-LR multiple interactions ISO RGD:10451 6480464 allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA] more ... CTD PMID:21684301 , PMID:32061150 microcystin-LR affects expression ISO RGD:10451 6480464 cyanoginosin LR affects the expression of CYP2E1 protein CTD PMID:32061150 microcystin-LR increases expression ISO RGD:10451 6480464 cyanoginosin LR results in increased expression of CYP2E1 mRNA, cyanoginosin LR results in increased expression of CYP2E1 protein CTD PMID:21684301 midazolam increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Midazolam CTD PMID:17590308 mirex decreases expression EXP 6480464 Mirex results in decreased expression of CYP2E1 protein CTD PMID:3113478 Monobutylphthalate decreases activity EXP 6480464 monobutyl phthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 monocrotophos increases expression EXP 6480464 Monocrotophos results in increased expression of CYP2E1 protein CTD PMID:21445290 monocrotophos multiple interactions ISO RGD:1345007 6480464 [Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein more ... CTD PMID:22733800 monocrotophos increases expression ISO RGD:1345007 6480464 Monocrotophos results in increased expression of CYP2E1 mRNA, Monocrotophos results in increased expression of CYP2E1 protein CTD PMID:22733800 monocrotophos increases activity ISO RGD:1345007 6480464 Monocrotophos results in increased activity of CYP2E1 protein CTD PMID:22733800 monosodium L-glutamate multiple interactions ISO RGD:10451 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2E1 mRNA, [Sodium Glutamate co-treated with Tea] affects the expression of CYP2E1 mRNA CTD PMID:25663641 muconic acid multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of muconic acid CTD PMID:15051535 myricetin decreases activity ISO RGD:1345007 6480464 myricetin results in decreased activity of CYP2E1 protein CTD PMID:29753067 myricitrin multiple interactions ISO RGD:10451 6480464 myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 N'-(2,4-dimethylphenyl)-N-methylformamidine increases expression EXP 6480464 U 40481 results in increased expression of CYP2E1 protein CTD PMID:31029719 N,N-diethyl-m-toluamide increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of DEET CTD PMID:11854147 N,N-diethyl-m-toluamide multiple interactions ISO RGD:1345007 6480464 [fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA CTD PMID:27091632 N,N-diisopropyltryptamine decreases activity ISO RGD:1345007 6480464 N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein CTD PMID:26599973 N,N-diisopropyltryptamine multiple interactions ISO RGD:1345007 6480464 [N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 N,N-dimethylformamide affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein polymorphism affects the metabolism of Dimethylformamide CTD PMID:11305777 N,N-dimethylformamide increases expression ISO RGD:1345007 6480464 Dimethylformamide results in increased expression of CYP2E1 protein CTD PMID:29984871 N,N-dimethylformamide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Dimethylformamide CTD PMID:31501917 N,N-dimethylformamide increases abundance ISO RGD:1345007 6480464 CYP2E1 polymorphism results in increased abundance of Dimethylformamide metabolite CTD PMID:31501917 N,N-dimethylformamide multiple interactions ISO RGD:10451 6480464 CYP2E1 protein affects the reaction [Dimethylformamide results in increased activity of GPT protein], CYP2E1 protein affects the reaction [Dimethylformamide results in increased expression of HSP90B1 protein] CTD PMID:31501917 N,N-dimethylformamide increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Dimethylformamide CTD PMID:9817075 N,N-dimethylformamide affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Dimethylformamide CTD PMID:15772367 N,N-dimethylformamide increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Dimethylformamide CTD PMID:10207612 N-acetyl-1,4-benzoquinone imine multiple interactions ISO RGD:10451 6480464 CYP2E1 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:19679878 N-acetyl-1,4-benzoquinone imine increases abundance ISO RGD:1345007 6480464 CYP2E1 protein results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:24661219 N-acetyl-1,4-benzoquinone imine increases chemical synthesis EXP 6480464 CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine CTD PMID:20566340 N-acetyl-1,4-benzoquinone imine increases chemical synthesis ISO RGD:1345007 6480464 CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine CTD PMID:20566340 N-acetyl-L-cysteine multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] more ... CTD PMID:21424224 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:1345007 6480464 Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] CTD PMID:35713687 N-acetyl-L-cysteine multiple interactions ISO RGD:10451 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA], Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:30423402 N-acetyl-S-phenyl-L-cysteine multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of S-phenyl-N-acetylcysteine CTD PMID:15051535 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:10451 6480464 [AQP4 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium] which affects the expression of CYP2E1 mRNA CTD PMID:20615459 N-methylformamide increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of methylformamide CTD PMID:1538706 N-methylformamide increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of methylformamide CTD PMID:1538706 N-methylformamide multiple interactions EXP 6480464 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] more ... CTD PMID:1538706 N-Nitrosodi-n-butylamine multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine, [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine CTD PMID:11035158 , PMID:11733072 N-Nitrosodi-n-propylamine multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine more ... CTD PMID:11035158 more ... N-Nitrosodi-n-propylamine increases activity ISO RGD:1345007 6480464 CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine CTD PMID:15728263 N-Nitrosodi-n-propylamine affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine CTD PMID:10910959 N-Nitrosodiethanolamine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of N-nitrosodiethanolamine CTD PMID:18616954 N-nitrosodiethylamine multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine more ... CTD PMID:11035158 more ... N-nitrosodiethylamine increases expression ISO RGD:10451 6480464 Diethylnitrosamine results in increased expression of CYP2E1 protein CTD PMID:36442531 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of CYP2E1 mRNA, Diethylnitrosamine results in increased expression of CYP2E1 protein CTD PMID:30423403 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of CYP2E1 mRNA, Diethylnitrosamine results in decreased expression of CYP2E1 protein CTD PMID:19638242 more ... N-nitrosodiethylamine increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Diethylnitrosamine CTD PMID:18056438 N-nitrosodiethylamine multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:14656948 more ... N-nitrosodiethylamine increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to Diethylnitrosamine CTD PMID:14669323 N-nitrosodiethylamine multiple interactions ISO RGD:10451 6480464 CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA] more ... CTD PMID:18056438 , PMID:36442531 N-nitrosodiethylamine increases activity ISO RGD:1345007 6480464 CYP2E1 protein results in increased activity of Diethylnitrosamine CTD PMID:15728263 N-nitrosodiethylamine affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Diethylnitrosamine CTD PMID:2655891 N-nitrosodimethylamine multiple interactions ISO RGD:1345007 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine] which results in increased mutagenesis of HPRT1 gene more ... CTD PMID:11181492 more ... N-nitrosodimethylamine decreases activity ISO RGD:1345007 6480464 Dimethylnitrosamine results in decreased activity of CYP2E1 protein CTD PMID:24561005 N-nitrosodimethylamine affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Dimethylnitrosamine CTD PMID:16235733 , PMID:2655891 N-nitrosodimethylamine decreases methylation EXP 6480464 CYP2E1 protein results in decreased methylation of Dimethylnitrosamine CTD PMID:3113478 , PMID:8194125 N-nitrosodimethylamine decreases expression ISO RGD:10451 6480464 Dimethylnitrosamine results in decreased expression of CYP2E1 mRNA CTD PMID:11356909 N-nitrosodimethylamine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Dimethylnitrosamine CTD PMID:15763544 N-nitrosodimethylamine multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine], S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] CTD PMID:15763544 , PMID:8117321 N-nitrosodimethylamine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Dimethylnitrosamine CTD PMID:12464242 , PMID:15242818 N-nitrosodimethylamine decreases methylation ISO RGD:1345007 6480464 CYP2E1 protein results in decreased methylation of Dimethylnitrosamine CTD PMID:11181492 N-Nitrosomethylethylamine multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of methylethylnitrosamine CTD PMID:11600130 N-nitrosomorpholine multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosomorpholine CTD PMID:11774366 N-nitrosopiperidine multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosopiperidine CTD PMID:11774366 N-Nitrosopyrrolidine multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of N-Nitrosopyrrolidine CTD PMID:11774366 N-Nitrosopyrrolidine decreases expression ISO RGD:1345007 6480464 N-Nitrosopyrrolidine results in decreased expression of CYP2E1 mRNA CTD PMID:32234424 NADP zwitterion multiple interactions ISO RGD:1345007 6480464 [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] CTD PMID:11181492 NADP zwitterion multiple interactions EXP 6480464 [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein CTD PMID:24713513 NADP(+) multiple interactions ISO RGD:1345007 6480464 [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] CTD PMID:11181492 NADP(+) multiple interactions EXP 6480464 [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein CTD PMID:24713513 naphthalene increases expression ISO RGD:1345007 6480464 naphthalene results in increased expression of CYP2E1 mRNA CTD PMID:20500019 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of CYP2E1 mRNA CTD PMID:24136188 Neferine multiple interactions EXP 6480464 neferine inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2E1 mRNA] CTD PMID:30423403 neobavaisoflavone multiple interactions EXP 6480464 neobavaisoflavone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol] CTD PMID:31870919 neobavaisoflavone decreases activity EXP 6480464 neobavaisoflavone results in decreased activity of CYP2E1 protein CTD PMID:31870919 neomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 nicotinamide multiple interactions EXP 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein], [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] CTD PMID:27919644 nicotine increases expression EXP 6480464 Nicotine results in increased expression of CYP2E1 protein CTD PMID:16434548 nifedipine decreases activity ISO RGD:10451 6480464 Nifedipine results in decreased activity of CYP2E1 protein CTD PMID:18420780 nitric oxide multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Nitric Oxide CTD PMID:18845238 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of CYP2E1 mRNA CTD PMID:33484710 nitroglycerin increases expression EXP 6480464 Nitroglycerin results in increased expression of CYP2E1 mRNA CTD PMID:12102619 Notopterol decreases activity ISO RGD:1345007 6480464 notopterol results in decreased activity of CYP2E1 protein CTD PMID:32198085 Notopterol increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of notopterol CTD PMID:32198085 Notopterol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol] more ... CTD PMID:32198085 o-anisidine increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2-anisidine CTD PMID:15828049 O-methyleugenol decreases expression ISO RGD:1345007 6480464 methyleugenol results in decreased expression of CYP2E1 mRNA CTD PMID:32234424 o-xylene increases expression EXP 6480464 2-xylene results in increased expression of CYP2E1 protein CTD PMID:8517779 , PMID:8996725 o-xylene multiple interactions EXP 6480464 Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein] CTD PMID:8996725 o-xylene multiple interactions ISO RGD:1345007 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene] CTD PMID:8558417 o-xylene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 2-xylene CTD PMID:17156750 o-xylene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 2-xylene CTD PMID:8558417 obeticholic acid decreases expression ISO RGD:1345007 6480464 obeticholic acid results in decreased expression of CYP2E1 mRNA CTD PMID:27939613 ochratoxin A increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to ochratoxin A CTD PMID:11189750 octadecanoic acid increases activity ISO RGD:1345007 6480464 stearic acid results in increased activity of CYP2E1 protein CTD PMID:26739624 okadaic acid decreases expression ISO RGD:10451 6480464 Okadaic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:25270620 oleanolic acid multiple interactions EXP 6480464 Oleanolic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:25111957 oleanolic acid decreases expression EXP 6480464 Oleanolic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:18706400 oleanolic acid decreases expression ISO RGD:10451 6480464 Oleanolic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:18706400 oleanolic acid multiple interactions ISO RGD:10451 6480464 Oleanolic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:10355542 oleic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26854922 oleic acid increases expression ISO RGD:1345007 6480464 Oleic Acid results in increased expression of CYP2E1 mRNA CTD PMID:30611723 oleic acid multiple interactions ISO RGD:1345007 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:30611723 oltipraz affects activity ISO RGD:1345007 6480464 oltipraz affects the activity of CYP2E1 protein CTD PMID:10775323 omeprazole multiple interactions ISO RGD:1345007 6480464 Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 orphenadrine multiple interactions ISO RGD:1345007 6480464 Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin], Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin] CTD PMID:9241656 orphenadrine decreases activity ISO RGD:1345007 6480464 Orphenadrine results in decreased activity of CYP2E1 protein CTD PMID:9241656 oxirane multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of ethylene] which results in increased abundance of Ethylene Oxide CTD PMID:21785163 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of CYP2E1 mRNA CTD PMID:23439660 ozone decreases expression ISO RGD:10451 6480464 Ozone results in decreased expression of CYP2E1 mRNA CTD PMID:12763052 ozone multiple interactions ISO RGD:10451 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CYP2E1 mRNA CTD PMID:34911549 p-cresol increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 4-cresol CTD PMID:16174805 p-xylene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of 4-xylene CTD PMID:8558417 p-xylene multiple interactions ISO RGD:1345007 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene] CTD PMID:8558417 p-xylene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 4-xylene CTD PMID:17156750 paclitaxel multiple interactions EXP 6480464 turmeric extract affects the reaction [Paclitaxel results in decreased activity of CYP2E1 protein] CTD PMID:24882083 paclitaxel decreases activity EXP 6480464 Paclitaxel results in decreased activity of CYP2E1 protein CTD PMID:24882083 paracetamol multiple interactions ISO RGD:10451 6480464 [Acetaminophen results in increased activity of CYP2E1 protein] inhibits the reaction [PPARA protein results in increased oxidation of Fatty Acids] more ... CTD PMID:11376689 more ... paracetamol decreases expression ISO RGD:1345007 6480464 Acetaminophen results in decreased expression of CYP2E1 mRNA, Acetaminophen results in decreased expression of CYP2E1 protein CTD PMID:29067470 , PMID:32112222 paracetamol increases expression ISO RGD:1345007 6480464 Acetaminophen results in increased expression of CYP2E1 mRNA, Acetaminophen results in increased expression of CYP2E1 protein CTD PMID:23728527 more ... paracetamol increases activity ISO RGD:10451 6480464 Acetaminophen results in increased activity of CYP2E1 protein CTD PMID:19256530 more ... paracetamol increases activity EXP 6480464 Acetaminophen results in increased activity of CYP2E1 protein CTD PMID:19932728 paracetamol decreases expression ISO RGD:10451 6480464 Acetaminophen results in decreased expression of CYP2E1 mRNA, Acetaminophen results in decreased expression of CYP2E1 protein CTD PMID:15576447 more ... paracetamol decreases activity ISO RGD:10451 6480464 Acetaminophen results in decreased activity of CYP2E1 protein CTD PMID:26772156 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CYP2E1 mRNA CTD PMID:17126469 more ... paracetamol increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Acetaminophen CTD PMID:21130154 paracetamol increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Acetaminophen CTD PMID:11323178 more ... paracetamol increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Acetaminophen CTD PMID:19002106 paracetamol increases expression ISO RGD:10451 6480464 Acetaminophen results in increased expression of CYP2E1 mRNA, Acetaminophen results in increased expression of CYP2E1 protein CTD PMID:12958197 more ... paracetamol affects expression ISO RGD:10451 6480464 Acetaminophen affects the expression of CYP2E1 mRNA CTD PMID:17562736 paracetamol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen more ... CTD PMID:11212141 more ... paracetamol increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to Acetaminophen CTD PMID:11212141 , PMID:28762043 paracetamol increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Acetaminophen, CYP2E1 results in increased metabolism of Acetaminophen CTD PMID:12464242 more ... paracetamol affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Acetaminophen CTD PMID:15772367 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CYP2E1 mRNA, Acetaminophen results in increased expression of CYP2E1 protein CTD PMID:18798224 , PMID:33350580 paracetamol multiple interactions EXP 6480464 [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:11562448 more ... paracetamol affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to Acetaminophen CTD PMID:19256530 paraquat multiple interactions ISO RGD:10451 6480464 [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA more ... CTD PMID:16510128 , PMID:20964710 paraquat multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein co-treated with Paraquat] results in increased expression of KLF6 protein more ... CTD PMID:22486562 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of CYP2E1 mRNA CTD PMID:32680482 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CYP2E1 mRNA, Paraquat results in increased expression of CYP2E1 protein CTD PMID:20553223 more ... paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein more ... CTD PMID:20553223 , PMID:23159886 paraquat increases activity EXP 6480464 Paraquat results in increased activity of CYP2E1 protein CTD PMID:20888808 parathion affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Parathion CTD PMID:12669189 parathion increases expression ISO RGD:10451 6480464 Parathion results in increased expression of CYP2E1 mRNA CTD PMID:34813904 pentachlorobenzene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of pentachlorobenzene CTD PMID:7747284 pentachlorobenzene increases expression EXP 6480464 pentachlorobenzene results in increased expression of CYP2E1 protein CTD PMID:10696772 pentachlorobenzene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of pentachlorobenzene CTD PMID:7747284 pentachlorophenol increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Pentachlorophenol CTD PMID:7747284 pentachlorophenol multiple interactions ISO RGD:1345007 6480464 Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene], Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 perfluorononanoic acid decreases expression ISO RGD:1345007 6480464 perfluoro-n-nonanoic acid results in decreased expression of CYP2E1 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid affects expression ISO RGD:10451 6480464 perfluorooctane sulfonic acid affects the expression of CYP2E1 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid decreases activity ISO RGD:1345007 6480464 perfluorooctane sulfonic acid results in decreased activity of CYP2E1 protein CTD PMID:35121066 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1345007 6480464 perfluorooctane sulfonic acid results in decreased expression of CYP2E1 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1345007 6480464 perfluorooctane sulfonic acid inhibits the reaction [CYP2E1 protein results in increased oxidation of Chlorzoxazone] CTD PMID:21964418 perfluorooctanoic acid decreases expression ISO RGD:10451 6480464 perfluorooctanoic acid results in decreased expression of CYP2E1 mRNA CTD PMID:17681415 perfluorooctanoic acid decreases expression ISO RGD:1345007 6480464 perfluorooctanoic acid results in decreased expression of CYP2E1 mRNA CTD PMID:35548680 perfluorooctanoic acid decreases activity ISO RGD:1345007 6480464 perfluorooctanoic acid results in decreased activity of CYP2E1 protein CTD PMID:35121066 perfluorooctanoic acid multiple interactions ISO RGD:10451 6480464 Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of CYP2E1 mRNA] CTD PMID:23626681 perfluorooctanoic acid affects expression ISO RGD:10451 6480464 perfluorooctanoic acid affects the expression of CYP2E1 mRNA CTD PMID:19429403 phenacetin affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Phenacetin CTD PMID:15879494 phenanthrene multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene CTD PMID:19766613 phenanthrene multiple interactions ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene CTD PMID:19766613 phenethyl caffeate multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA CTD PMID:20360939 phenethyl caffeate multiple interactions ISO RGD:10451 6480464 caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] CTD PMID:18436364 phenethyl isothiocyanate multiple interactions EXP 6480464 phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] more ... CTD PMID:7562599 , PMID:7601153 phenethyl isothiocyanate decreases activity ISO RGD:1345007 6480464 phenethyl isothiocyanate results in decreased activity of CYP2E1 protein CTD PMID:10616189 , PMID:17582584 phenethyl isothiocyanate decreases expression EXP 6480464 phenethyl isothiocyanate results in decreased expression of CYP2E1 protein CTD PMID:7601153 phenformin increases expression EXP 6480464 Phenformin results in increased expression of CYP2E1 mRNA CTD PMID:31324951 phenobarbital multiple interactions EXP 6480464 [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2E1 protein, Choline deficiency promotes the reaction [Phenobarbital results in increased expression of CYP2E1 protein] CTD PMID:18798224 , PMID:30842367 phenobarbital decreases expression ISO RGD:10451 6480464 Phenobarbital results in decreased expression of CYP2E1 mRNA CTD PMID:30503582 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CYP2E1 mRNA, Phenobarbital results in increased expression of CYP2E1 protein CTD PMID:18798224 , PMID:23273579 phenobarbital increases activity EXP 6480464 Phenobarbital results in increased activity of CYP2E1 protein CTD PMID:15490126 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of CYP2E1 mRNA, Phenobarbital results in decreased expression of CYP2E1 protein CTD PMID:15596064 more ... phenol increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Phenol CTD PMID:11701230 phenol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Phenol CTD PMID:8211999 phenol multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol more ... CTD PMID:8211999 phenol multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of Phenol CTD PMID:15051535 phenthoate decreases activity ISO RGD:1345007 6480464 phenthoate results in decreased activity of CYP2E1 protein CTD PMID:22634058 phenthoate multiple interactions ISO RGD:1345007 6480464 phenthoate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 phenylglyoxylic acid multiple interactions ISO RGD:1345007 6480464 CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 phenytoin multiple interactions ISO RGD:1345007 6480464 NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA] CTD PMID:18206661 phenytoin decreases expression EXP 6480464 Phenytoin results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 phenytoin increases expression ISO RGD:1345007 6480464 Phenytoin results in increased expression of CYP2E1 mRNA, Phenytoin results in increased expression of CYP2E1 protein CTD PMID:18206661 PhIP increases expression ISO RGD:1345007 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of CYP2E1 mRNA CTD PMID:29362861 PhIP multiple interactions ISO RGD:1345007 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:29362861 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1345007 6480464 Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] more ... CTD PMID:8531136 more ... phorbol 13-acetate 12-myristate increases expression ISO RGD:1345007 6480464 Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein CTD PMID:8798623 phthalaldehyde decreases expression ISO RGD:10451 6480464 o-Phthalaldehyde results in decreased expression of CYP2E1 mRNA CTD PMID:20112102 pioglitazone multiple interactions ISO RGD:10451 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 piperidin-2-one increases abundance ISO RGD:10451 6480464 CYP2E1 protein results in increased abundance of 2-piperidone CTD PMID:23811823 Pipermethystine increases expression EXP 6480464 pipermethystine results in increased expression of CYP2E1 protein CTD PMID:17329236 potassium dichromate increases expression ISO RGD:10451 6480464 Potassium Dichromate results in increased expression of CYP2E1 mRNA CTD PMID:23608068 primaquine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Primaquine CTD PMID:19616568 primaquine multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased expression of HBG2 protein] which affects the susceptibility to Primaquine CTD PMID:19616568 prochloraz decreases expression ISO RGD:1345007 6480464 prochloraz results in decreased expression of CYP2E1 mRNA CTD PMID:20035023 procymidone multiple interactions ISO RGD:10451 6480464 procymidone results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:12787915 procymidone increases expression ISO RGD:10451 6480464 procymidone results in increased expression of CYP2E1 mRNA CTD PMID:12787915 profenofos decreases activity ISO RGD:1345007 6480464 profenofos results in decreased activity of CYP2E1 protein CTD PMID:22634058 profenofos multiple interactions ISO RGD:1345007 6480464 profenofos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 progesterone affects expression ISO RGD:10451 6480464 Progesterone affects the expression of CYP2E1 mRNA CTD PMID:17251523 progesterone multiple interactions EXP 6480464 Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein] CTD PMID:18407866 prop-2-yn-1-ol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of propargyl alcohol CTD PMID:11306107 propacetamol increases expression ISO RGD:10451 6480464 propacetamol results in increased expression of CYP2E1 protein CTD PMID:29574133 propacetamol multiple interactions ISO RGD:10451 6480464 kaempferol inhibits the reaction [propacetamol results in increased expression of CYP2E1 protein] CTD PMID:29574133 propan-2-ol multiple interactions EXP 6480464 2-Propanol binds to and results in increased expression of CYP2E1 protein, 2-Propanol inhibits the reaction [CYP2E1 protein results in increased reduction of Tirapazamine] CTD PMID:3337723 , PMID:7710944 propan-2-ol increases expression EXP 6480464 2-Propanol results in increased expression of CYP2E1 protein CTD PMID:9118891 propetamphos multiple interactions EXP 6480464 [cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein CTD PMID:25926273 propetamphos increases activity EXP 6480464 propetamphos results in increased activity of CYP2E1 protein CTD PMID:25926273 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of CYP2E1 protein CTD PMID:7986207 propylparaben decreases activity EXP 6480464 propylparaben results in decreased activity of CYP2E1 protein CTD PMID:27432241 psoralen decreases expression ISO RGD:10451 6480464 Ficusin results in decreased expression of CYP2E1 protein CTD PMID:22173200 psoralidin decreases activity EXP 6480464 psoralidin results in decreased activity of CYP2E1 protein CTD PMID:31870919 psoralidin multiple interactions EXP 6480464 psoralidin inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol] CTD PMID:31870919 puerarin multiple interactions ISO RGD:10451 6480464 puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] CTD PMID:18038910 puerarin increases expression ISO RGD:10451 6480464 puerarin results in increased expression of CYP2E1 protein CTD PMID:18038910 purpurin decreases activity ISO RGD:1345007 6480464 purpurin results in decreased activity of CYP2E1 protein CTD PMID:12379470 purpurin multiple interactions EXP 6480464 purpurin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of CYP2E1 protein] CTD PMID:35838105 purpurogallin multiple interactions EXP 6480464 purpurogallin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 pyrazinecarboxamide multiple interactions EXP 6480464 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein more ... CTD PMID:27919644 pyrazines increases activity EXP 6480464 Pyrazines results in increased activity of CYP2E1 protein CTD PMID:8117321 pyrazines multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein], allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein] CTD PMID:8117321 pyrazines increases expression EXP 6480464 Pyrazines results in increased expression of CYP2E1 protein CTD PMID:8117321 pyrene decreases expression EXP 6480464 pyrene results in decreased expression of CYP2E1 mRNA CTD PMID:30240548 pyridine multiple interactions ISO RGD:1345007 6480464 CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA], Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] CTD PMID:12147272 pyridine increases activity EXP 6480464 pyridine results in increased activity of CYP2E1 protein CTD PMID:11181506 more ... pyridine increases expression EXP 6480464 pyridine results in increased expression of CYP2E1 mRNA, pyridine results in increased expression of CYP2E1 protein CTD PMID:10215695 more ... pyridine multiple interactions EXP 6480464 [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:10215695 more ... pyridine increases expression ISO RGD:1345007 6480464 pyridine results in increased expression of CYP2E1 protein CTD PMID:8074729 pyridine decreases activity ISO RGD:1345007 6480464 pyridine results in decreased activity of CYP2E1 protein CTD PMID:12464242 pyridine N-oxide increases expression EXP 6480464 pyridine N-oxide results in increased expression of CYP2E1 protein CTD PMID:1379807 pyridines multiple interactions EXP 6480464 Pyridines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 pyrogallol increases activity ISO RGD:10451 6480464 Pyrogallol results in increased activity of CYP2E1 protein CTD PMID:18789925 pyrogallol multiple interactions ISO RGD:10451 6480464 resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP2E1 protein], resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP2E1 mRNA] CTD PMID:18789925 pyrogallol increases expression ISO RGD:10451 6480464 Pyrogallol results in increased expression of CYP2E1 mRNA CTD PMID:18789925 quartz decreases expression EXP 6480464 Quartz results in decreased expression of CYP2E1 mRNA CTD PMID:19836432 quercetin multiple interactions ISO RGD:10451 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein] CTD PMID:26218279 quercetin decreases activity ISO RGD:1345007 6480464 Quercetin results in decreased activity of CYP2E1 protein CTD PMID:28232125 , PMID:29753067 quercetin multiple interactions ISO RGD:1345007 6480464 Quercetin inhibits the reaction [[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased phosphorylation of MAP2K4 protein] more ... CTD PMID:16963249 , PMID:19325051 quercetin decreases activity ISO RGD:10451 6480464 Quercetin results in decreased activity of CYP2E1 protein CTD PMID:18420780 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] more ... CTD PMID:11306697 more ... quercetin 3-O-beta-D-galactopyranoside decreases activity ISO RGD:10451 6480464 hyperoside results in decreased activity of CYP2E1 protein CTD PMID:26772156 quercetin 3-O-beta-D-galactopyranoside multiple interactions ISO RGD:10451 6480464 hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein] CTD PMID:26772156 quinacrine multiple interactions EXP 6480464 Quinacrine binds to and results in decreased activity of CYP2E1 protein CTD PMID:18754103 quinacrine decreases expression EXP 6480464 Quinacrine results in decreased expression of CYP2E1 protein CTD PMID:18754103 quinidine decreases activity ISO RGD:10451 6480464 Quinidine results in decreased activity of CYP2E1 protein CTD PMID:18420780 quinoline increases hydroxylation ISO RGD:1345007 6480464 CYP2E1 protein results in increased hydroxylation of quinoline CTD PMID:8824525 quinoline increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of quinoline CTD PMID:8824525 quinolines multiple interactions EXP 6480464 Quinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 rac-1,2-dichloropropane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of propylene dichloride CTD PMID:1664256 reactive oxygen species multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species more ... CTD PMID:18845238 , PMID:22222162 reactive oxygen species increases chemical synthesis ISO RGD:1345007 6480464 CYP2E1 protein results in increased chemical synthesis of Reactive Oxygen Species CTD PMID:10498651 reactive oxygen species multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species CTD PMID:25601990 reactive oxygen species decreases response to substance EXP 6480464 CYP2E1 protein results in decreased susceptibility to Reactive Oxygen Species CTD PMID:12470497 reactive oxygen species affects chemical synthesis EXP 6480464 CYP2E1 protein affects the chemical synthesis of Reactive Oxygen Species CTD PMID:14693714 resveratrol increases expression ISO RGD:10451 6480464 resveratrol results in increased expression of CYP2E1 mRNA CTD PMID:22610192 resveratrol multiple interactions ISO RGD:10451 6480464 Resveratrol inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone] more ... CTD PMID:18789925 more ... resveratrol affects expression EXP 6480464 resveratrol affects the expression of CYP2E1 mRNA CTD PMID:15748624 resveratrol decreases activity ISO RGD:10451 6480464 resveratrol analog results in decreased activity of CYP2E1 protein, resveratrol results in decreased activity of CYP2E1 protein CTD PMID:16684708 more ... retinyl acetate multiple interactions ISO RGD:10451 6480464 [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA CTD PMID:28123100 Retrorsine increases expression EXP 6480464 retrorsine results in increased expression of CYP2E1 CTD PMID:24799337 riddelliine increases expression EXP 6480464 riddelliine results in increased expression of CYP2E1 mRNA CTD PMID:18047722 , PMID:18047727 rifampicin increases activity ISO RGD:1345007 6480464 Rifampin results in increased activity of CYP2E1 protein CTD PMID:18071298 rifampicin decreases expression ISO RGD:10451 6480464 Rifampin results in decreased expression of CYP2E1 mRNA CTD PMID:30503582 rifampicin multiple interactions ISO RGD:10451 6480464 [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein CTD PMID:25835148 rifampicin decreases expression ISO RGD:1345007 6480464 Rifampin results in decreased expression of CYP2E1 mRNA CTD PMID:22258563 rifampicin multiple interactions ISO RGD:1345007 6480464 [Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein more ... CTD PMID:22733800 rifampicin increases expression ISO RGD:1345007 6480464 Rifampin results in increased expression of CYP2E1 mRNA, Rifampin results in increased expression of CYP2E1 protein CTD PMID:18071298 , PMID:22733800 rifampicin multiple interactions EXP 6480464 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein more ... CTD PMID:15132840 , PMID:27919644 rotenone increases expression EXP 6480464 Rotenone results in increased expression of CYP2E1 mRNA CTD PMID:28374803 S-adenosyl-L-methioninate multiple interactions EXP 6480464 S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] more ... CTD PMID:15763544 S-adenosyl-L-methioninate decreases activity EXP 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-adenosyl-L-methioninate decreases activity ISO RGD:1345007 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-adenosyl-L-methioninate multiple interactions ISO RGD:10451 6480464 S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein], S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:15983038 , PMID:22683606 S-adenosyl-L-methionine decreases activity EXP 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-adenosyl-L-methionine multiple interactions EXP 6480464 S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] more ... CTD PMID:15763544 S-adenosyl-L-methionine multiple interactions ISO RGD:10451 6480464 S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein], S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:15983038 , PMID:22683606 S-adenosyl-L-methionine decreases activity ISO RGD:1345007 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-butyl-DL-homocysteine (S,R)-sulfoximine increases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in increased susceptibility to Buthionine Sulfoximine, CYP2E1 results in increased susceptibility to Buthionine Sulfoximine CTD PMID:12086689 , PMID:12566070 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:1345007 6480464 Buthionine Sulfoximine promotes the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein] more ... CTD PMID:10498651 more ... safrole decreases activity ISO RGD:1345007 6480464 Safrole results in decreased activity of CYP2E1 protein CTD PMID:15778010 Salidroside multiple interactions ISO RGD:10451 6480464 rhodioloside inhibits the reaction [furan results in increased expression of CYP2E1 protein] CTD PMID:34450210 salvianolic acid B multiple interactions EXP 6480464 salvianolic acid B inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:27989594 satraplatin decreases activity ISO RGD:1345007 6480464 satraplatin results in decreased activity of CYP2E1 protein CTD PMID:24882083 SB 203580 multiple interactions ISO RGD:1345007 6480464 SB 203580 promotes the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]], SB 203580 promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA] CTD PMID:22486562 SCH772984 multiple interactions EXP 6480464 SCH772984 inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA], SCH772984 inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein] CTD PMID:31585129 selenium atom multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] CTD PMID:21424224 senecionine increases expression ISO RGD:1345007 6480464 senecionine results in increased expression of CYP2E1 mRNA CTD PMID:26100227 senecionine decreases expression ISO RGD:10451 6480464 senecionine results in decreased expression of CYP2E1 mRNA CTD PMID:31606820 sevoflurane increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of sevoflurane CTD PMID:7879937 Shikonin decreases activity ISO RGD:1345007 6480464 shikonin results in decreased activity of CYP2E1 protein CTD PMID:28941798 Shikonin decreases activity EXP 6480464 shikonin results in decreased activity of CYP2E1 protein CTD PMID:28941798 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of CYP2E1 mRNA CTD PMID:32721576 silicon dioxide decreases expression ISO RGD:10451 6480464 Silicon Dioxide results in decreased expression of CYP2E1 mRNA CTD PMID:29341224 sirolimus multiple interactions ISO RGD:1345007 6480464 Sirolimus affects the reaction [FXN protein affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol]] CTD PMID:33017621 skatole decreases expression ISO RGD:1345007 6480464 Skatole results in decreased expression of CYP2E1 mRNA CTD PMID:28571685 sodium arsenite increases expression ISO RGD:10451 6480464 sodium arsenite results in increased expression of CYP2E1 mRNA, sodium arsenite results in increased expression of CYP2E1 protein CTD PMID:25065748 , PMID:29044176 sodium arsenite decreases expression ISO RGD:1345007 6480464 sodium arsenite results in decreased expression of CYP2E1 mRNA CTD PMID:29301061 sodium arsenite decreases response to substance ISO RGD:1345007 6480464 CYP2E1 protein results in decreased susceptibility to sodium arsenite CTD PMID:19154403 sodium arsenite decreases expression ISO RGD:10451 6480464 sodium arsenite results in decreased expression of CYP2E1 mRNA CTD PMID:17350061 , PMID:17451858 sodium chromate multiple interactions EXP 6480464 Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)] more ... CTD PMID:1903091 staurosporine multiple interactions EXP 6480464 Staurosporine inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] CTD PMID:11306697 staurosporine increases expression EXP 6480464 Staurosporine results in increased expression of CYP2E1 mRNA CTD PMID:11306697 streptozocin decreases expression ISO RGD:10451 6480464 Streptozocin results in decreased expression of CYP2E1 protein CTD PMID:12700423 streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:24815820 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of CYP2E1 mRNA, Streptozocin results in increased expression of CYP2E1 protein CTD PMID:11752103 more ... styrene decreases metabolic processing ISO RGD:1345007 6480464 CYP2E1 gene polymorphism results in decreased metabolism of Styrene CTD PMID:16125881 styrene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Styrene CTD PMID:26463279 styrene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Styrene CTD PMID:24320693 styrene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Styrene CTD PMID:1664256 styrene increases expression ISO RGD:1345007 6480464 Styrene results in increased expression of CYP2E1 mRNA CTD PMID:21030303 styrene affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to Styrene CTD PMID:12604177 more ... styrene increases expression EXP 6480464 Styrene results in increased expression of CYP2E1 mRNA, Styrene results in increased expression of CYP2E1 protein CTD PMID:16418063 , PMID:18202523 styrene multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA], gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein] CTD PMID:18202523 styrene multiple interactions ISO RGD:10451 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene, [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene CTD PMID:12746132 , PMID:20470765 styrene increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Styrene CTD PMID:15110085 styrene affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of Styrene CTD PMID:12746132 styrene multiple interactions ISO RGD:1345007 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene more ... CTD PMID:12464798 more ... styrene affects oxidation ISO RGD:1345007 6480464 CYP2E1 protein affects the oxidation of Styrene CTD PMID:16872732 styrene increases response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Styrene, CYP2E1 protein results in increased susceptibility to Styrene CTD PMID:11535253 , PMID:16872732 styrene affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the metabolism of Styrene, CYP2E1 protein affects the metabolism of Styrene CTD PMID:12464798 more ... styrene oxide increases chemical synthesis ISO RGD:1345007 6480464 CYP2E1 results in increased chemical synthesis of styrene oxide, CYP2E1 results in increased chemical synthesis of styrene oxide analog CTD PMID:22366341 Sudan I increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775 sulforaphane multiple interactions ISO RGD:10451 6480464 sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA], sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein] CTD PMID:21684301 sulforaphane increases expression ISO RGD:10451 6480464 sulforaphane results in increased expression of CYP2E1 mRNA CTD PMID:30529165 sunitinib increases expression EXP 6480464 sunitinib results in increased expression of CYP2E1 mRNA CTD PMID:26797788 tamoxifen decreases activity ISO RGD:10451 6480464 Tamoxifen results in decreased activity of CYP2E1 protein CTD PMID:18420780 tamoxifen multiple interactions ISO RGD:10451 6480464 Carbon Tetrachloride promotes the reaction [Tamoxifen results in decreased expression of CYP2E1 mRNA] more ... CTD PMID:29974145 tamoxifen decreases expression ISO RGD:10451 6480464 Tamoxifen results in decreased expression of CYP2E1 mRNA, Tamoxifen results in decreased expression of CYP2E1 protein CTD PMID:29974145 taurine multiple interactions ISO RGD:10451 6480464 Taurine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein], Taurine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:20067817 , PMID:20166895 tebuconazole decreases expression ISO RGD:1345007 6480464 tebuconazole results in decreased expression of CYP2E1 mRNA CTD PMID:30458266 tebuconazole increases expression EXP 6480464 tebuconazole results in increased expression of CYP2E1 protein CTD PMID:29923317 tenofovir disoproxil fumarate decreases activity ISO RGD:1345007 6480464 Tenofovir results in decreased activity of CYP2E1 protein CTD PMID:17162464 tert-butyl ethyl ether increases expression EXP 6480464 ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA, ethyl tert-butyl ether results in increased expression of CYP2E1 protein CTD PMID:24090815 testosterone increases expression ISO RGD:10451 6480464 Testosterone results in increased expression of CYP2E1 mRNA, Testosterone results in increased expression of CYP2E1 protein CTD PMID:20403060 , PMID:7839370 Tetrachlorobisphenol A increases expression ISO RGD:1345007 6480464 tetrachlorodian results in increased expression of CYP2E1 mRNA CTD PMID:31326446 tetrachloroethene increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Tetrachloroethylene CTD PMID:17433522 tetrachloroethene decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to Tetrachloroethylene CTD PMID:29897530 tetrachloroethene multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased oxidation of Tetrachloroethylene] which results in increased abundance of Trichloroacetic Acid CTD PMID:29897530 tetrachloroethene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Tetrachloroethylene CTD PMID:29897530 tetrachloromethane decreases activity ISO RGD:10451 6480464 Carbon Tetrachloride results in decreased activity of CYP2E1 protein CTD PMID:17038628 more ... tetrachloromethane decreases expression ISO RGD:10451 6480464 Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA, Carbon Tetrachloride results in decreased expression of CYP2E1 protein CTD PMID:12466116 more ... tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of CYP2E1 protein CTD PMID:17710613 , PMID:25899501 tetrachloromethane increases activity ISO RGD:10451 6480464 Carbon Tetrachloride results in increased activity of CYP2E1 protein CTD PMID:25445725 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA, Carbon Tetrachloride results in decreased expression of CYP2E1 protein CTD PMID:14706259 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CYP2E1 mRNA, Carbon Tetrachloride results in increased expression of CYP2E1 protein CTD PMID:11903743 more ... tetrachloromethane decreases activity EXP 6480464 Carbon Tetrachloride results in decreased activity of CYP2E1 protein CTD PMID:14706259 more ... tetrachloromethane increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Carbon Tetrachloride CTD PMID:15797236 more ... tetrachloromethane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Carbon Tetrachloride CTD PMID:7601153 tetrachloromethane affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Carbon Tetrachloride CTD PMID:15772367 tetrachloromethane increases degradation EXP 6480464 Carbon Tetrachloride results in increased degradation of CYP2E1 protein CTD PMID:12679053 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of CYP2E1 mRNA CTD PMID:17805973 tetrachloromethane multiple interactions EXP 6480464 acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] more ... CTD PMID:11903743 more ... tetrachloromethane affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to Carbon Tetrachloride CTD PMID:15962327 tetrachloromethane increases activity ISO RGD:1345007 6480464 Carbon Tetrachloride results in increased activity of CYP2E1 protein CTD PMID:17710613 tetrachloromethane multiple interactions ISO RGD:1345007 6480464 Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] more ... CTD PMID:8531136 , PMID:9143349 tetrachloromethane increases expression ISO RGD:10451 6480464 Carbon Tetrachloride results in increased expression of CYP2E1 mRNA, Carbon Tetrachloride results in increased expression of CYP2E1 protein CTD PMID:17610925 more ... tetrachloromethane multiple interactions ISO RGD:10451 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:10355542 more ... tetrachlorophenol increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of tetrachlorophenol CTD PMID:7747284 tetracycline multiple interactions ISO RGD:10451 6480464 bicyclol inhibits the reaction [Tetracycline results in decreased expression of CYP2E1 mRNA] CTD PMID:19427351 tetracycline decreases expression ISO RGD:10451 6480464 Tetracycline results in decreased expression of CYP2E1 mRNA CTD PMID:19427351 tetrahydrocurcumin multiple interactions ISO RGD:10451 6480464 tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA], tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:30423402 tetraphene increases expression ISO RGD:10451 6480464 benz(a)anthracene results in increased expression of CYP2E1 mRNA CTD PMID:26377693 thallium increases response to substance EXP 6480464 CYP2E1 results in increased susceptibility to Thallium CTD PMID:20549620 theobromine multiple interactions ISO RGD:1345007 6480464 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine], Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] CTD PMID:10215755 theobromine increases chemical synthesis ISO RGD:1345007 6480464 CYP2E1 protein results in increased chemical synthesis of Theobromine CTD PMID:1302044 theobromine increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Theobromine CTD PMID:10215755 theophylline affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Theophylline CTD PMID:15985363 theophylline increases chemical synthesis ISO RGD:1345007 6480464 CYP2E1 protein results in increased chemical synthesis of Theophylline CTD PMID:1302044 theophylline affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Theophylline CTD PMID:15948934 , PMID:16841220 theophylline affects hydroxylation ISO RGD:1345007 6480464 CYP2E1 promoter SNP affects the hydroxylation of Theophylline CTD PMID:16841220 thiacloprid decreases expression ISO RGD:1345007 6480464 thiacloprid results in decreased expression of CYP2E1 mRNA CTD PMID:32201337 thiacloprid multiple interactions ISO RGD:1345007 6480464 [clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein more ... CTD PMID:32201337 thiamine(1+) chloride multiple interactions EXP 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein], [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] CTD PMID:27919644 thiazoles multiple interactions EXP 6480464 [Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein CTD PMID:7587954 thioacetamide multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of Thioacetamide] which results in increased chemical synthesis of thioacetamide-S-oxide more ... CTD PMID:18374380 , PMID:29763686 thioacetamide increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Thioacetamide CTD PMID:29763686 thioacetamide decreases activity ISO RGD:10451 6480464 Thioacetamide results in decreased activity of CYP2E1 protein CTD PMID:29763686 thioacetamide increases expression ISO RGD:10451 6480464 Thioacetamide results in increased expression of CYP2E1 protein CTD PMID:30625377 thioacetamide decreases expression ISO RGD:10451 6480464 Thioacetamide results in decreased expression of CYP2E1 protein CTD PMID:27349771 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2E1 mRNA, Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein] CTD PMID:20036707 , PMID:28943392 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CYP2E1 protein CTD PMID:20036707 thioacetamide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Thioacetamide CTD PMID:18374380 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of CYP2E1 mRNA CTD PMID:16297948 , PMID:34492290 thiophanate-methyl increases expression EXP 6480464 Thiophanate results in increased expression of CYP2E1 protein CTD PMID:10096430 thioridazine decreases activity ISO RGD:1345007 6480464 Thioridazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 thiostrepton decreases expression ISO RGD:1345007 6480464 Thiostrepton results in decreased expression of CYP2E1 mRNA CTD PMID:22321511 thiram increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Thiram CTD PMID:12458634 thiram multiple interactions EXP 6480464 Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] CTD PMID:12458634 thymoquinone multiple interactions EXP 6480464 thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2E1 protein] CTD PMID:35437842 Tiopronin multiple interactions EXP 6480464 Tiopronin inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] CTD PMID:19683030 tirapazamine multiple interactions EXP 6480464 1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] more ... CTD PMID:7710944 titanium dioxide increases expression ISO RGD:10451 6480464 titanium dioxide results in increased expression of CYP2E1 mRNA CTD PMID:23557971 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of CYP2E1 mRNA CTD PMID:30012374 toluene affects response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism affects the susceptibility to Toluene CTD PMID:17292523 toluene decreases methylation ISO RGD:1345007 6480464 Toluene results in decreased methylation of CYP2E1 5' UTR CTD PMID:32437847 toluene affects activity ISO RGD:1345007 6480464 Toluene affects the activity of CYP2E1 protein CTD PMID:25963742 toluene increases expression ISO RGD:1345007 6480464 Toluene results in increased expression of CYP2E1 mRNA CTD PMID:16581535 more ... toluene affects methylation ISO RGD:1345007 6480464 Toluene affects the methylation of CYP2E1 promoter CTD PMID:25963742 toluene increases expression EXP 6480464 Toluene results in increased expression of CYP2E1 mRNA, Toluene results in increased expression of CYP2E1 protein CTD PMID:12919724 more ... toluene increases activity EXP 6480464 Toluene results in increased activity of CYP2E1 protein CTD PMID:12919724 more ... toluene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Toluene CTD PMID:8461037 toluene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Toluene CTD PMID:8461037 toluene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Toluene CTD PMID:8620572 toluene multiple interactions ISO RGD:10451 6480464 [Toluene co-treated with Benzene] results in increased activity of CYP2E1 protein CTD PMID:18455711 toluene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein alternative form results in increased metabolism of Toluene, CYP2E1 protein results in increased metabolism of Toluene CTD PMID:12464242 more ... toluene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Toluene CTD PMID:1994898 toluene multiple interactions EXP 6480464 [Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Toluene more ... CTD PMID:1994898 more ... toluene multiple interactions ISO RGD:1345007 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene], Smoke affects the reaction [Toluene affects the methylation of CYP2E1 promoter] CTD PMID:25963742 , PMID:8558417 trabectedin decreases activity EXP 6480464 trabectedin results in decreased activity of CYP2E1 protein CTD PMID:12154027 trans-1,2-dichloroethene multiple interactions EXP 6480464 1 more ... CTD PMID:7871537 , PMID:9851676 trans-1,2-dichloroethene decreases expression EXP 6480464 1, 2-dichloroethylene results in decreased expression of CYP2E1 protein CTD PMID:9671540 trans-1,2-dichloroethene multiple interactions ISO RGD:10451 6480464 1 more ... CTD PMID:10828257 trans-1,2-dichloroethene decreases activity ISO RGD:1345007 6480464 1, 2-dichloroethylene results in decreased activity of CYP2E1 protein CTD PMID:32199159 trans-1,2-dichloroethene decreases activity EXP 6480464 1, 2-dichloroethylene results in decreased activity of CYP2E1 protein CTD PMID:15205388 more ... trans-caffeic acid multiple interactions EXP 6480464 caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 trans-cinnamic acid decreases activity ISO RGD:1345007 6480464 cinnamic acid analog results in decreased activity of CYP2E1 protein CTD PMID:15072549 transfluthrin multiple interactions EXP 6480464 transfluthrin results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:22080754 tranylcypromine decreases activity ISO RGD:1345007 6480464 Tranylcypromine results in decreased activity of CYP2E1 protein CTD PMID:15155557 triadimefon decreases expression ISO RGD:10451 6480464 triadimefon results in decreased expression of CYP2E1 mRNA CTD PMID:16730040 trichloroacetic acid multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased oxidation of Tetrachloroethylene] which results in increased abundance of Trichloroacetic Acid, [CYP2E1 protein results in increased oxidation of Trichloroethylene] which results in increased abundance of Trichloroacetic Acid CTD PMID:29897530 trichloroethene increases activity ISO RGD:1345007 6480464 Trichloroethylene results in increased activity of CYP2E1 protein CTD PMID:17710613 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CYP2E1 mRNA CTD PMID:33387578 trichloroethene multiple interactions ISO RGD:1345007 6480464 [CYP2E1 protein results in increased oxidation of Trichloroethylene] which results in increased abundance of Trichloroacetic Acid CTD PMID:29897530 trichloroethene increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Trichloroethylene CTD PMID:1664256 , PMID:29897530 trichloroethene increases activity EXP 6480464 Trichloroethylene results in increased activity of CYP2E1 protein CTD PMID:17710613 , PMID:8620572 trichloroethene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Trichloroethylene CTD PMID:10774820 more ... trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of CYP2E1 protein CTD PMID:8620572 trichloroethene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Trichloroethylene CTD PMID:1739413 more ... trichloroethene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Trichloroethylene CTD PMID:17710613 , PMID:7871537 trichloroethene increases metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein results in increased metabolism of Trichloroethylene CTD PMID:10841534 , PMID:18350910 trichloroethene increases response to substance ISO RGD:1345007 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Trichloroethylene CTD PMID:19351467 trichloroethene increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Trichloroethylene CTD PMID:17433522 trichloroethene multiple interactions EXP 6480464 1 more ... CTD PMID:1739413 more ... trichloroethene increases expression ISO RGD:10451 6480464 Trichloroethylene results in increased expression of CYP2E1 protein CTD PMID:10753203 trichloroethene multiple interactions ISO RGD:10451 6480464 [diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene CTD PMID:10774820 trichloroethene affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of Trichloroethylene CTD PMID:17710613 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of CYP2E1 mRNA CTD PMID:21515302 troglitazone increases expression ISO RGD:10451 6480464 troglitazone results in increased expression of CYP2E1 mRNA CTD PMID:28973697 tryptamines multiple interactions ISO RGD:1345007 6480464 [Tryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 tryptamines decreases activity ISO RGD:1345007 6480464 Tryptamines analog results in decreased activity of CYP2E1 protein CTD PMID:26599973 umbelliferone multiple interactions ISO RGD:10451 6480464 7-hydroxycoumarin inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein] CTD PMID:24661945 uranium atom multiple interactions EXP 6480464 [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA, Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] CTD PMID:17126469 urethane multiple interactions ISO RGD:10451 6480464 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane] more ... CTD PMID:12704224 more ... urethane increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of Urethane CTD PMID:1664256 urethane affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of Urethane CTD PMID:12704224 more ... urethane increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Urethane CTD PMID:15790490 urethane affects oxidation ISO RGD:10451 6480464 CYP2E1 protein affects the oxidation of Urethane CTD PMID:20205516 urethane affects hydroxylation ISO RGD:10451 6480464 CYP2E1 protein affects the hydroxylation of Urethane CTD PMID:15879495 urethane decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to Urethane CTD PMID:17093202 urethane decreases metabolic processing ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased metabolism of Urethane CTD PMID:12704224 ursodeoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:10453939 usnic acid multiple interactions ISO RGD:1345007 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP2E1 mRNA CTD PMID:22777745 usnic acid decreases expression ISO RGD:1345007 6480464 usnic acid results in decreased expression of CYP2E1 mRNA CTD PMID:21953288 , PMID:22777745 valproic acid decreases expression ISO RGD:1345007 6480464 Valproic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:29154799 , PMID:29501571 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CYP2E1 mRNA CTD PMID:35594946 valproic acid multiple interactions ISO RGD:1345007 6480464 allyl sulfide inhibits the reaction [Valproic Acid results in increased expression of and results in increased activity of CYP2E1 protein] more ... CTD PMID:33007364 valproic acid multiple interactions ISO RGD:10451 6480464 allyl sulfide inhibits the reaction [Valproic Acid results in increased expression of and results in decreased activity of CYP2E1 protein] more ... CTD PMID:33007364 valproic acid increases expression ISO RGD:10451 6480464 Valproic Acid results in increased expression of CYP2E1 mRNA CTD PMID:33007364 valproic acid increases expression ISO RGD:1345007 6480464 Valproic Acid results in increased expression of CYP2E1 mRNA CTD PMID:33007364 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 vancomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 vanoxerine dihydrochloride multiple interactions ISO RGD:1345007 6480464 [Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine CTD PMID:11502731 vanoxerine dihydrochloride decreases degradation ISO RGD:1345007 6480464 CYP2E1 protein results in decreased degradation of vanoxerine CTD PMID:11502731 vinclozolin multiple interactions ISO RGD:10451 6480464 [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein more ... CTD PMID:17686559 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of CYP2E1 protein CTD PMID:25929820 vinclozolin affects expression ISO RGD:10451 6480464 vinclozolin affects the expression of CYP2E1 mRNA, vinclozolin affects the expression of CYP2E1 protein CTD PMID:8921505 vinyl carbamate affects metabolic processing ISO RGD:1345007 6480464 CYP2E1 protein affects the metabolism of vinyl carbamate CTD PMID:11181492 vinyl carbamate increases oxidation ISO RGD:1345007 6480464 CYP2E1 protein results in increased oxidation of vinyl carbamate CTD PMID:1664256 vinyl carbamate affects oxidation EXP 6480464 CYP2E1 protein affects the oxidation of vinyl carbamate CTD PMID:17296623 vinyl carbamate multiple interactions EXP 6480464 diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] CTD PMID:17296623 vinyl carbamate decreases expression ISO RGD:10451 6480464 vinyl carbamate results in decreased expression of CYP2E1 protein CTD PMID:11134547 vinyl carbamate decreases activity ISO RGD:10451 6480464 vinyl carbamate results in decreased activity of CYP2E1 protein CTD PMID:11134547 vinyl carbamate multiple interactions ISO RGD:10451 6480464 [diallyl sulfone results in decreased activity of CYP2E1 protein] which affects the susceptibility to vinyl carbamate, diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] CTD PMID:17341656 , PMID:20205516 vinyl carbamate affects oxidation ISO RGD:10451 6480464 CYP2E1 protein affects the oxidation of vinyl carbamate CTD PMID:20205516 vinyl carbamate affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of vinyl carbamate CTD PMID:11181492 vinyl carbamate multiple interactions ISO RGD:1345007 6480464 [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] CTD PMID:11181492 vitamin D multiple interactions ISO RGD:10451 6480464 Vitamin D inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2E1 protein] CTD PMID:36442531 vitamin E multiple interactions ISO RGD:1345007 6480464 Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Paraquat] results in increased expression of KLF6 protein] more ... CTD PMID:10498651 , PMID:22486562 vitamin E multiple interactions EXP 6480464 Vitamin E inhibits the reaction [decamethrin results in increased expression of CYP2E1 mRNA] CTD PMID:25439240 water multiple interactions ISO RGD:10451 6480464 [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP2E1 mRNA CTD PMID:29335169 wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] CTD PMID:11306697 wortmannin multiple interactions ISO RGD:1345007 6480464 Wortmannin inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]], Wortmannin inhibits the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA] CTD PMID:22486562 Wuweizisu C decreases activity ISO RGD:10451 6480464 schizandrin C results in decreased activity of CYP2E1 protein CTD PMID:25753323 XL147 multiple interactions ISO RGD:10451 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of CYP2E1 mRNA CTD PMID:20607812 zinc atom multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] more ... CTD PMID:21424224 , PMID:27919644 zinc atom multiple interactions ISO RGD:10451 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of CYP2E1 protein CTD PMID:24155903 zinc atom increases expression ISO RGD:10451 6480464 Zinc deficiency results in increased expression of CYP2E1 protein CTD PMID:24155903 zinc protoporphyrin multiple interactions EXP 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA more ... CTD PMID:26747958 zinc protoporphyrin multiple interactions ISO RGD:1345007 6480464 zinc protoporphyrin inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]], zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]] CTD PMID:19325051 zinc sulfate multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] more ... CTD PMID:15920153 , PMID:20118189 zinc sulfate increases expression EXP 6480464 Zinc Sulfate results in increased expression of CYP2E1 mRNA CTD PMID:20553223 zinc sulfate multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA], Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA] CTD PMID:20553223 zinc sulfate multiple interactions ISO RGD:1345007 6480464 CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate] more ... CTD PMID:12566070 zinc(0) multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] more ... CTD PMID:21424224 , PMID:27919644 zinc(0) increases expression ISO RGD:10451 6480464 Zinc deficiency results in increased expression of CYP2E1 protein CTD PMID:24155903 zinc(0) multiple interactions ISO RGD:10451 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of CYP2E1 protein CTD PMID:24155903 zingerone multiple interactions EXP 6480464 zingerone inhibits the reaction [1 more ... CTD PMID:28442378 , PMID:30720227
