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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chgb | Rat | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of CHGB mRNA; Nicotine results in increased expression of CHGB more ... | CTD | PMID:1907749 | Chgb | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHGB mRNA | CTD | PMID:22206623 | Chgb | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Chgb (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of CHGB mRNA | CTD | PMID:22206623 | Chgb | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHGB mRNA | CTD | PMID:17942748 | Chgb | Rat | 17beta-estradiol | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of CHGB mRNA | CTD | PMID:30165855 | Chgb | Rat | 17beta-estradiol 3-benzoate | increases expression | EXP | | 6480464 | estradiol 3-benzoate results in increased expression of CHGB mRNA | CTD | PMID:32741896 | Chgb | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHGB mRNA | CTD | PMID:17942748 | Chgb | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Chgb (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CHGB mRNA | CTD | PMID:21570461 | Chgb | Rat | 2-methylcholine | affects expression | ISO | CHGB (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of CHGB mRNA | CTD | PMID:21179406 | Chgb | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | Chgb | Rat | aldehydo-D-glucose | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Chgb | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | Chgb | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CHGB mRNA | CTD | PMID:16483693 | Chgb | Rat | arsenous acid | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of CHGB mRNA | CTD | PMID:15761015 | Chgb | Rat | benzo[a]pyrene | increases methylation | ISO | CHGB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CHGB 3' UTR | CTD | PMID:27901495 | Chgb | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Chgb | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Chgb (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of CHGB mRNA | CTD | PMID:34319233 | Chgb | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CHGB mRNA | CTD | PMID:25181051 | Chgb | Rat | bisphenol A | decreases expression | ISO | CHGB (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CHGB mRNA | CTD | PMID:33670352 | Chgb | Rat | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Chgb | Rat | cadmium dichloride | decreases expression | ISO | CHGB (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of CHGB mRNA | CTD | PMID:26472689 | Chgb | Rat | camptothecin | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Camptothecin results in increased expression of CHGB mRNA | CTD | PMID:38460933 | Chgb | Rat | CGP 52608 | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CHGB gene] | CTD | PMID:28238834 | Chgb | Rat | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of CHGB mRNA | CTD | PMID:17452286 | Chgb | Rat | chlorpyrifos | affects expression | ISO | Chgb (Mus musculus) | 6480464 | Chlorpyrifos affects the expression of CHGB mRNA | CTD | PMID:29156651 | Chgb | Rat | choline | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Chgb | Rat | ciguatoxin CTX1B | affects expression | ISO | Chgb (Mus musculus) | 6480464 | Ciguatoxins affects the expression of CHGB mRNA | CTD | PMID:18353800 | Chgb | Rat | cisplatin | decreases expression | ISO | CHGB (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CHGB mRNA | CTD | PMID:27392435 | Chgb | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CHGB mRNA | CTD | PMID:26577399 | Chgb | Rat | D-glucose | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Chgb | Rat | diarsenic trioxide | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of CHGB mRNA | CTD | PMID:15761015 | Chgb | Rat | diazinon | increases expression | EXP | | 6480464 | Diazinon results in increased expression of CHGB mRNA | CTD | PMID:17452286 | Chgb | Rat | diazinon | decreases expression | EXP | | 6480464 | Diazinon results in decreased expression of CHGB mRNA | CTD | PMID:18812211 | Chgb | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Chgb | Rat | dieldrin | decreases expression | EXP | | 6480464 | Dieldrin results in decreased expression of CHGB mRNA | CTD | PMID:18812211 | Chgb | Rat | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Chgb | Rat | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Chgb | Rat | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Chgb | Rat | dorsomorphin | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Chgb | Rat | ethanol | affects splicing | ISO | Chgb (Mus musculus) | 6480464 | Ethanol affects the splicing of CHGB mRNA | CTD | PMID:30319688 | Chgb | Rat | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of CHGB mRNA | CTD | PMID:18035473 | Chgb | Rat | folic acid | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHGB mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Chgb | Rat | fructose | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Chgb | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CHGB mRNA | CTD | PMID:27387713 | Chgb | Rat | genistein | decreases expression | ISO | Chgb (Mus musculus) | 6480464 | Genistein results in decreased expression of CHGB mRNA | CTD | PMID:32186404 | Chgb | Rat | glucose | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... | CTD | PMID:37567420 | Chgb | Rat | kainic acid | increases expression | EXP | | 6480464 | Kainic Acid results in increased expression of CHGB mRNA | CTD | PMID:9427505 | Chgb | Rat | L-methionine | multiple interactions | ISO | Chgb (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Chgb | Rat | lithium chloride | decreases expression | ISO | Chgb (Mus musculus) | 6480464 | Lithium Chloride results in decreased expression of CHGB mRNA | CTD | PMID:33901603 | Chgb | Rat | lycopene | decreases expression | ISO | CHGB (Homo sapiens) | 6480464 | lycopene results in decreased expression of CHGB mRNA | CTD | PMID:16886892 | Chgb | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | Chgb | Rat | methylmercury chloride | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of CHGB mRNA | CTD | PMID:28001369 | Chgb | Rat | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of CHGB mRNA | CTD | PMID:21515302 | Chgb | Rat | N-ethyl-N-nitrosourea | increases expression | EXP | | 6480464 | Ethylnitrosourea results in increased expression of CHGB mRNA | CTD | PMID:15954086 | Chgb | Rat | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of CHGB mRNA | CTD | PMID:18812211 | Chgb | Rat | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of CHGB mRNA; Nicotine results in increased expression of CHGB more ... | CTD | PMID:1907749 | Chgb | Rat | Oxotremorine | increases expression | EXP | | 6480464 | Oxotremorine results in increased expression of CHGB mRNA; Oxotremorine results in increased expression of CHGB more ... | CTD | PMID:1907749 | Chgb | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Chgb (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of CHGB mRNA | CTD | PMID:37995155 | Chgb | Rat | reserpine | increases expression | EXP | | 6480464 | Reserpine results in increased expression of CHGB mRNA; Reserpine results in increased expression of CHGB more ... | CTD | PMID:1907749|PMID:8189248|PMID:8361347 | Chgb | Rat | resveratrol | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | resveratrol results in increased expression of CHGB mRNA | CTD | PMID:25888808 | Chgb | Rat | rotenone | increases oxidation | EXP | | 6480464 | Rotenone results in increased oxidation of CHGB protein | CTD | PMID:30951809 | Chgb | Rat | S-nitrosoglutathione | decreases expression | ISO | CHGB (Homo sapiens) | 6480464 | S-Nitrosoglutathione results in decreased expression of CHGB mRNA | CTD | PMID:38825487 | Chgb | Rat | SB 431542 | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Chgb | Rat | silicon dioxide | decreases expression | ISO | CHGB (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of CHGB mRNA | CTD | PMID:25895662 | Chgb | Rat | sodium dichromate | decreases expression | ISO | Chgb (Mus musculus) | 6480464 | sodium bichromate results in decreased expression of CHGB mRNA | CTD | PMID:31558096 | Chgb | Rat | sotorasib | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHGB mRNA | CTD | PMID:36139627 | Chgb | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | Chgb | Rat | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of CHGB mRNA | CTD | PMID:21515302 | Chgb | Rat | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of CHGB protein | CTD | PMID:35544339 | Chgb | Rat | titanium dioxide | decreases methylation | ISO | Chgb (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of CHGB gene | CTD | PMID:35295148 | Chgb | Rat | trametinib | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHGB mRNA | CTD | PMID:36139627 | Chgb | Rat | trichostatin A | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | trichostatin A results in increased expression of CHGB mRNA | CTD | PMID:24935251 | Chgb | Rat | triclosan | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Triclosan results in increased expression of CHGB mRNA | CTD | PMID:30510588 | Chgb | Rat | triptonide | increases expression | ISO | Chgb (Mus musculus) | 6480464 | triptonide results in increased expression of CHGB mRNA | CTD | PMID:33045310 | Chgb | Rat | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of CHGB mRNA | CTD | PMID:21515302 | Chgb | Rat | tunicamycin | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of CHGB mRNA | CTD | PMID:29453283 | Chgb | Rat | urethane | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Urethane results in increased expression of CHGB mRNA | CTD | PMID:28818685 | Chgb | Rat | valproic acid | affects expression | ISO | CHGB (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CHGB mRNA | CTD | PMID:25979313 | Chgb | Rat | valproic acid | multiple interactions | ISO | CHGB (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Chgb | Rat | valproic acid | increases expression | ISO | CHGB (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CHGB mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:28001369 | Chgb | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of CHGB mRNA | CTD | PMID:20566332 | |