Mir101-2 (microRNA 101-2) - Rat Genome Database

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Gene: Mir101-2 (microRNA 101-2) Rattus norvegicus
Analyze
Symbol: Mir101-2
Name: microRNA 101-2
RGD ID: 2325609
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including negative regulation of necroptotic process; negative regulation of protein metabolic process; and negative regulation of signal transduction. Predicted to act upstream of or within several processes, including cellular response to mechanical stimulus; cellular response to tumor necrosis factor; and long-term synaptic potentiation. Predicted to be located in synapse. Predicted to be part of RISC complex. Orthologous to human MIR101-2 (microRNA 101-2); INTERACTS WITH aflatoxin B1; atrazine; bleomycin A2.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 101b; Mir101b; rno-mir-101b
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,273,922 - 236,274,018 (+)NCBIGRCr8
mRatBN7.21226,860,371 - 226,860,467 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,860,371 - 226,860,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,262,206 - 235,262,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,191,870 - 242,191,966 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,010,639 - 235,010,735 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,263,723 - 247,263,819 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,263,723 - 247,263,819 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,503,393 - 254,503,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1224,011,283 - 224,011,379 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (ISO)
synapse  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14691248   PMID:15345052   PMID:16381832   PMID:16766679   PMID:17604727   PMID:20395292   PMID:20403161   PMID:20548288   PMID:23185045   PMID:23227940   PMID:23390134   PMID:24349514  
PMID:25858512   PMID:25921548   PMID:25959411   PMID:27507301   PMID:27925653   PMID:30549198   PMID:30605239   PMID:31526851   PMID:38739522  


Genomics

Comparative Map Data
Mir101-2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,273,922 - 236,274,018 (+)NCBIGRCr8
mRatBN7.21226,860,371 - 226,860,467 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,860,371 - 226,860,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,262,206 - 235,262,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,191,870 - 242,191,966 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,010,639 - 235,010,735 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,263,723 - 247,263,819 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,263,723 - 247,263,819 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,503,393 - 254,503,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1224,011,283 - 224,011,379 (+)NCBICelera
Cytogenetic Map1q52NCBI
MIR101-2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3894,850,297 - 4,850,375 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl94,850,297 - 4,850,375 (+)EnsemblGRCh38hg38GRCh38
GRCh3794,850,297 - 4,850,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3694,840,296 - 4,840,374 (+)NCBINCBI36Build 36hg18NCBI36
Celera94,775,888 - 4,775,966 (+)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef94,805,891 - 4,805,969 (+)NCBIHuRef
CHM1_194,850,518 - 4,850,596 (+)NCBICHM1_1
T2T-CHM13v2.094,855,423 - 4,855,501 (+)NCBIT2T-CHM13v2.0
Mir101b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,112,679 - 29,112,775 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,112,679 - 29,112,775 (+)EnsemblGRCm39 Ensembl
GRCm381929,135,279 - 29,135,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,135,279 - 29,135,375 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,209,769 - 29,209,865 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1929,910,729 - 29,910,825 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1923.61NCBI
MIR101-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,194,328 - 93,194,382 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,194,309 - 93,194,399 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0193,749,531 - 93,749,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,749,512 - 93,749,602 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,380,331 - 93,380,385 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,103,859 - 93,103,913 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,869,446 - 93,869,500 (+)NCBIUU_Cfam_GSD_1.0
MIR101-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1217,152,783 - 217,152,873 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11217,152,783 - 217,152,873 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,988,419 - 242,988,509 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status (No longer updated)

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Capn8rno-miR-101b-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:6018
Count of gene targets:4034
Count of transcripts:4335
Interacting mature miRNAs:rno-miR-101b-3p, rno-miR-101b-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1234540191270518180Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
6480786Bw97Body weight QTL 975.03body mass (VT:0001259)body weight (CMO:0000012)1234540191237018045Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat


Expression

RNA-SEQ Expression

appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 5 11 42 38 28 15 28 68 28 3 11 13 10

Sequence


Ensembl Acc Id: ENSRNOT00000053655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1226,860,371 - 226,860,467 (+)Ensembl
Rnor_6.0 Ensembl1247,263,723 - 247,263,819 (+)Ensembl
RefSeq Acc Id: NR_031799
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81236,273,922 - 236,274,018 (+)NCBI
mRatBN7.21226,860,371 - 226,860,467 (+)NCBI
Rnor_6.01247,263,723 - 247,263,819 (+)NCBI
Rnor_5.01254,503,393 - 254,503,489 (+)NCBI
Celera1224,011,283 - 224,011,379 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325609 AgrOrtholog
BioCyc Gene G2FUF-55974 BioCyc
Ensembl Genes ENSRNOG00000035532 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053655 ENTREZGENE
miRBase MI0000648 ENTREZGENE
NCBI Gene 100313988 ENTREZGENE
PhenoGen Mir101-2 PhenoGen
RatGTEx ENSRNOG00000035532 RatGTEx
RNAcentral URS0000434E68 RNACentral
  URS000075AF72 RNACentral
  URS000075EB3E RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 Mir101-2  microRNA 101-2  Mir101b  microRNA 101b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-10-19 Mir101-2  microRNA 101-2  Mir101b  microRNA 101b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-10-19 Mir101b  microRNA 101b  Mir101-2  microRNA 101-2  Name and Symbol changed 629549 APPROVED
2015-04-09 Mir101b  microRNA 101b  Mir101b  microRNA mir-101b  Name updated 61478 APPROVED
2010-06-02 Mir101b  microRNA mir-101b      Symbol and Name status set to provisional 70820 PROVISIONAL