Epc1 (enhancer of polycomb homolog 1) - Rat Genome Database

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Gene: Epc1 (enhancer of polycomb homolog 1) Rattus norvegicus
Analyze
Symbol: Epc1
Name: enhancer of polycomb homolog 1
RGD ID: 2324280
Description: Predicted to enable chromatin-protein adaptor activity and enzyme-substrate adaptor activity. Involved in vascular associated smooth muscle cell differentiation. Predicted to be located in nuclear body; nuclear membrane; and nucleolus. Predicted to be part of NuA4 histone acetyltransferase complex; nucleosome; and piccolo histone acetyltransferase complex. Predicted to be active in site of double-strand break. Orthologous to human EPC1 (enhancer of polycomb homolog 1); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: enhancer of polycomb homolog 1 (Drosophila); LOC100362678; LOC307042
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,198,513 - 59,289,535 (-)NCBIGRCr8
mRatBN7.21754,503,358 - 54,594,444 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,503,358 - 54,594,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1757,670,117 - 57,762,113 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01761,673,219 - 61,765,221 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01755,840,859 - 55,932,853 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01757,303,968 - 57,394,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1757,304,933 - 57,394,985 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01755,332,012 - 55,423,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,040,151 - 63,131,954 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11763,050,987 - 63,115,013 (-)NCBI
Celera1750,484,141 - 50,575,159 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Neointima  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Enhancer of polycomb1 lessens neointima formation by potentiation of myocardin-induced smooth muscle differentiation. Joung H, etal., Atherosclerosis. 2012 May;222(1):84-91. doi: 10.1016/j.atherosclerosis.2012.02.015. Epub 2012 Feb 18.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
5. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.
Additional References at PubMed
PMID:10976108   PMID:12477932   PMID:14966270   PMID:15632090   PMID:17192267   PMID:19359245  


Genomics

Comparative Map Data
Epc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,198,513 - 59,289,535 (-)NCBIGRCr8
mRatBN7.21754,503,358 - 54,594,444 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,503,358 - 54,594,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1757,670,117 - 57,762,113 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01761,673,219 - 61,765,221 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01755,840,859 - 55,932,853 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01757,303,968 - 57,394,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1757,304,933 - 57,394,985 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01755,332,012 - 55,423,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,040,151 - 63,131,954 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11763,050,987 - 63,115,013 (-)NCBI
Celera1750,484,141 - 50,575,159 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
EPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381032,267,751 - 32,378,769 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1032,267,751 - 32,378,798 (-)EnsemblGRCh38hg38GRCh38
GRCh371032,556,679 - 32,667,697 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361032,597,865 - 32,676,119 (-)NCBINCBI36Build 36hg18NCBI36
Build 341032,597,864 - 32,676,119NCBI
Celera1032,323,085 - 32,401,333 (-)NCBICelera
Cytogenetic Map10p11.22NCBI
HuRef1032,276,952 - 32,387,816 (-)NCBIHuRef
CHM1_11032,558,317 - 32,669,300 (-)NCBICHM1_1
T2T-CHM13v2.01032,296,867 - 32,407,873 (-)NCBIT2T-CHM13v2.0
Epc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,435,951 - 6,516,108 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,435,951 - 6,516,108 (-)EnsemblGRCm39 Ensembl
GRCm38186,435,951 - 6,516,108 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,435,951 - 6,516,108 (-)EnsemblGRCm38mm10GRCm38
MGSCv37186,435,949 - 6,516,085 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36186,435,949 - 6,516,085 (-)NCBIMGSCv36mm8
Celera186,483,184 - 6,569,258 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.48NCBI
Epc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542923,817,254 - 23,909,946 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542923,819,261 - 23,910,279 (-)NCBIChiLan1.0ChiLan1.0
EPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2844,918,832 - 45,029,617 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11044,924,971 - 45,034,770 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01032,398,557 - 32,509,146 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11032,985,456 - 33,095,070 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1032,985,456 - 33,095,070 (-)Ensemblpanpan1.1panPan2
EPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1214,566,177 - 14,659,774 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl214,565,560 - 14,659,353 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha212,054,448 - 12,148,508 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0212,801,929 - 12,896,656 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl212,827,078 - 12,895,505 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1212,267,471 - 12,337,031 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0212,133,446 - 12,227,913 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0212,407,208 - 12,501,657 (+)NCBIUU_Cfam_GSD_1.0
Epc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934411,467,190 - 11,551,016 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936574964,619 - 1,050,571 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936574966,655 - 1,050,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1042,836,047 - 42,946,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11042,835,280 - 42,946,859 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21047,431,316 - 47,572,044 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1931,586,402 - 31,698,876 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl931,585,246 - 31,665,592 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605640,587,401 - 40,700,708 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248054,651,051 - 4,756,899 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248054,653,730 - 4,684,211 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Epc1
592 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:110
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000019968
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)175402992960463637Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000019968   ⟹   ENSRNOP00000019968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1754,503,358 - 54,594,425 (-)Ensembl
Rnor_6.0 Ensembl1757,304,933 - 57,394,985 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099548   ⟹   ENSRNOP00000085998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1754,565,066 - 54,567,707 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104942   ⟹   ENSRNOP00000086107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1754,503,361 - 54,532,359 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117368   ⟹   ENSRNOP00000078400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1754,503,361 - 54,566,580 (-)Ensembl
RefSeq Acc Id: NM_001309462   ⟹   NP_001296391
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,198,513 - 59,289,519 (-)NCBI
mRatBN7.21754,503,358 - 54,594,425 (-)NCBI
Rnor_6.01757,303,968 - 57,394,975 (-)NCBI
Celera1750,484,141 - 50,575,159 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003751704   ⟹   XP_003751752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,198,513 - 59,261,863 (-)NCBI
mRatBN7.21754,503,358 - 54,566,651 (-)NCBI
Rnor_6.01757,303,968 - 57,367,178 (-)NCBI
Rnor_5.01755,332,012 - 55,423,030 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095280   ⟹   XP_038951208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,198,513 - 59,261,753 (-)NCBI
mRatBN7.21754,503,358 - 54,569,408 (-)NCBI
RefSeq Acc Id: XM_039095281   ⟹   XP_038951209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,198,513 - 59,289,535 (-)NCBI
mRatBN7.21754,503,358 - 54,594,444 (-)NCBI
RefSeq Acc Id: XM_063276006   ⟹   XP_063132076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,198,513 - 59,261,762 (-)NCBI
RefSeq Acc Id: XR_005495222
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,204,344 - 59,261,753 (-)NCBI
mRatBN7.21754,509,189 - 54,566,656 (-)NCBI
RefSeq Acc Id: XP_003751752   ⟸   XM_003751704
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G2P8 (UniProtKB/TrEMBL),   A0A8I6GEL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001296391   ⟸   NM_001309462
- UniProtKB: D4A6E4 (UniProtKB/TrEMBL),   A6K9H9 (UniProtKB/TrEMBL),   A0A8I6GEL3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019968   ⟸   ENSRNOT00000019968
RefSeq Acc Id: XP_038951209   ⟸   XM_039095281
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GEL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951208   ⟸   XM_039095280
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GEL3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078400   ⟸   ENSRNOT00000117368
Ensembl Acc Id: ENSRNOP00000086107   ⟸   ENSRNOT00000104942
Ensembl Acc Id: ENSRNOP00000085998   ⟸   ENSRNOT00000099548
RefSeq Acc Id: XP_063132076   ⟸   XM_063276006
- Peptide Label: isoform X4
- UniProtKB: A0A8I6GEL3 (UniProtKB/TrEMBL)
Protein Domains
Enhancer of polycomb C-terminal   Enhancer of polycomb-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A6E4-F1-model_v2 AlphaFold D4A6E4 1-762 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700540
Promoter ID:EPDNEW_R11055
Type:initiation region
Name:Epc1_1
Description:enhancer of polycomb homolog 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01757,394,975 - 57,395,035EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324280 AgrOrtholog
BioCyc Gene G2FUF-8980 BioCyc
Ensembl Genes ENSRNOG00000014834 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019968.8 UniProtKB/TrEMBL
  ENSRNOT00000099548.1 UniProtKB/TrEMBL
  ENSRNOT00000104942.1 UniProtKB/TrEMBL
  ENSRNOT00000117368.1 UniProtKB/TrEMBL
InterPro Enhancer_polycomb UniProtKB/TrEMBL
  Enhancer_polycomb-like_N UniProtKB/TrEMBL
  Enhancer_polycomb_C UniProtKB/TrEMBL
KEGG Report rno:100362678 UniProtKB/TrEMBL
NCBI Gene 100362678 ENTREZGENE
PANTHER ENHANCER OF POLYCOMB HOMOLOG 1 UniProtKB/TrEMBL
  PTHR14898 UniProtKB/TrEMBL
Pfam E_Pc_C UniProtKB/TrEMBL
  EPL1 UniProtKB/TrEMBL
PhenoGen Epc1 PhenoGen
RatGTEx ENSRNOG00000014834 RatGTEx
UniProt A0A8I6A414_RAT UniProtKB/TrEMBL
  A0A8I6G2P8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GEL3 ENTREZGENE, UniProtKB/TrEMBL
  A6K9H9 ENTREZGENE, UniProtKB/TrEMBL
  D4A6E4 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM29_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Epc1  enhancer of polycomb homolog 1  Epc1  enhancer of polycomb homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-08-30 LOC100362678  enhancer of polycomb homolog 1  Epc1  enhancer of polycomb homolog 1 (Drosophila)  Data merged from RGD:1306027 737654 APPROVED
2012-08-30 Epc1  enhancer of polycomb homolog 1 (Drosophila)  LOC100362678  enhancer of polycomb homolog 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100362678  enhancer of polycomb homolog 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Epc1  enhancer of polycomb homolog 1 (Drosophila)   Epc1_predicted  enhancer of polycomb homolog 1 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Epc1_predicted  enhancer of polycomb homolog 1 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED