Igip (IgA-inducing protein) - Rat Genome Database

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Gene: Igip (IgA-inducing protein) Rattus norvegicus
Analyze
Symbol: Igip
Name: IgA-inducing protein
RGD ID: 2323374
Description: Orthologous to human IGIP (IgA inducing protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; (1->4)-beta-D-glucan (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC100363266; IgA-inducing protein homolog; IgA-inducing protein homolog (Bos taurus); LOC100363266
RGD Orthologs
Human
Mouse
Chinchilla
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,178,048 - 28,179,539 (+)NCBIGRCr8
mRatBN7.21827,904,018 - 27,905,509 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1828,031,376 - 28,032,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,793,221 - 28,794,712 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,128,148 - 28,129,639 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,115,051 - 29,125,681 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,124,428 - 29,124,589 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,822,794 - 28,832,500 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,933,544 - 28,936,783 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1827,626,004 - 27,637,112 (+)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Igip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,178,048 - 28,179,539 (+)NCBIGRCr8
mRatBN7.21827,904,018 - 27,905,509 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1828,031,376 - 28,032,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,793,221 - 28,794,712 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,128,148 - 28,129,639 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,115,051 - 29,125,681 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,124,428 - 29,124,589 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,822,794 - 28,832,500 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,933,544 - 28,936,783 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1827,626,004 - 27,637,112 (+)NCBICelera
Cytogenetic Map18p11NCBI
IGIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,125,937 - 140,129,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,125,937 - 140,129,392 (+)EnsemblGRCh38hg38GRCh38
GRCh375139,505,522 - 139,508,977 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,485,705 - 139,488,575 (+)NCBINCBI36Build 36hg18NCBI36
Celera5135,581,337 - 135,584,207 (+)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5134,648,693 - 134,651,563 (+)NCBIHuRef
CHM1_15138,938,626 - 138,941,496 (+)NCBICHM1_1
T2T-CHM13v2.05140,651,032 - 140,654,487 (+)NCBIT2T-CHM13v2.0
Igip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,433,154 - 36,434,531 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,431,732 - 36,434,570 (+)EnsemblGRCm39 Ensembl
GRCm381836,300,101 - 36,301,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,298,679 - 36,301,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,456,604 - 36,461,142 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,668,732 - 36,677,615 (+)NCBIMGSCv36mm8
Celera1836,752,843 - 36,757,381 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Igip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955418527,380 - 536,136 (-)NCBIChiLan1.0ChiLan1.0
Igip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,467,265 - 152,471,674 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,143,906 - 9,144,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,139,225 - 9,144,234 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12141,899,334 - 141,900,161 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,814,933 - 147,815,760 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IGIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,769,596 - 42,778,885 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,778,554 - 42,778,712 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603435,106,317 - 35,109,177 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474332,894,082 - 32,899,173 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:163
Count of miRNA genes:130
Interacting mature miRNAs:143
Transcripts:ENSRNOT00000073131
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat

Markers in Region
RH131734  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21827,905,185 - 27,905,366 (+)MAPPERmRatBN7.2
Rnor_6.01829,124,439 - 29,124,619NCBIRnor6.0
Rnor_5.01828,832,173 - 28,832,353UniSTSRnor5.0
RGSC_v3.41828,936,466 - 28,936,646UniSTSRGSC3.4
Celera1827,635,870 - 27,636,050UniSTS
RH 3.4 Map18390.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 23 30 14 19 14 8 10 58 27 29 11 8
Low 20 27 27 27 1 16 8 12
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000073131   ⟹   ENSRNOP00000065761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1829,124,428 - 29,124,589 (+)Ensembl
RefSeq Acc Id: NM_001400840   ⟹   NP_001387769
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81828,178,048 - 28,179,539 (+)NCBI
mRatBN7.21827,904,018 - 27,905,509 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001387769 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSRNOP00000065761   ⟸   ENSRNOT00000073131
RefSeq Acc Id: NP_001387769   ⟸   NM_001400840

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R8G5-F1-model_v2 AlphaFold M0R8G5 1-53 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323374 AgrOrtholog
BioCyc Gene G2FUF-7878 BioCyc
Ensembl Genes ENSRNOG00000049067 Ensembl
NCBI Gene 100363266 ENTREZGENE
PhenoGen Igip PhenoGen
RatGTEx ENSRNOG00000049067 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-16 Igip  IgA-inducing protein  Igip  IgA-inducing protein homolog (Bos taurus)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-09-10 Igip  IgA-inducing protein homolog (Bos taurus)  LOC100363266  hypothetical protein LOC100363266  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100363266  hypothetical protein LOC100363266      Symbol and Name status set to provisional 70820 PROVISIONAL