Slbpl (stem-loop binding protein like) - Rat Genome Database

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Gene: Slbpl (stem-loop binding protein like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Slbpl (Ensembl: LOC100363294)
Name: stem-loop binding protein like (Ensembl:stem-loop binding protein-like)
RGD ID: 2323347
Description: Predicted to enable histone pre-mRNA stem-loop binding activity and mRNA binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage and mRNA transport. Predicted to be part of histone pre-mRNA 3'end processing complex. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: LOC100363294; SLBP2; stem loop binding protein 2; stem-loop binding protein-like; uncharacterized protein LOC100363294
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81826,630,179 - 26,637,694 (+)NCBIGRCr8
mRatBN7.21826,356,478 - 26,363,577 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,356,474 - 26,363,577 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,483,848 - 26,490,947 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,247,484 - 27,254,585 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01826,582,383 - 26,589,484 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01827,550,426 - 27,557,699 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1827,554,062 - 27,557,699 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,263,511 - 27,270,893 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,229,636 - 27,233,043 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1826,094,180 - 26,101,113 (+)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:22467188  


Genomics

Variants

.
Variants in Slbpl
21 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
12904690Cm129Cardiac mass QTL 1290.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)181194427326548295Rat
12904689Cm128Cardiac mass QTL 1280.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)181194427326548295Rat
12904693Am20Aortic mass QTL 200.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)181194427326548295Rat
12904695Kidm73Kidney mass QTL 730.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)181194427326548295Rat
12904691Cm130Cardiac mass QTL 1300.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)181194427326548295Rat
12904680Bw189Body weight QTL 1890.019body mass (VT:0001259)body weight (CMO:0000012)181194427326548295Rat
2301410Bp317Blood pressure QTL 3170.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194427326548295Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4
Low 2 22 20 18 5 18 34 18 33
Below cutoff 1 8 19 13 11 13 2 2 25 10 2 3 2

Sequence


RefSeq Acc Id: ENSRNOT00000088432   ⟹   ENSRNOP00000073645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,356,474 - 26,363,577 (+)Ensembl
Rnor_6.0 Ensembl1827,554,062 - 27,557,699 (+)Ensembl
RefSeq Acc Id: NM_001270416   ⟹   NP_001257345
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,595 - 26,637,694 (+)NCBI
mRatBN7.21826,356,478 - 26,363,577 (+)NCBI
Rnor_6.01827,550,595 - 27,557,699 (+)NCBI
Rnor_5.01827,263,511 - 27,270,893 (+)NCBI
Celera1826,094,180 - 26,101,113 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277047   ⟹   XP_063133117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,345 - 26,637,692 (+)NCBI
RefSeq Acc Id: XM_063277048   ⟹   XP_063133118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,348 - 26,637,692 (+)NCBI
RefSeq Acc Id: XR_010059535
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,345 - 26,637,692 (+)NCBI
RefSeq Acc Id: XR_010059536
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,345 - 26,637,692 (+)NCBI
RefSeq Acc Id: XR_010059537
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,179 - 26,637,692 (+)NCBI
RefSeq Acc Id: XR_010059538
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81826,630,179 - 26,637,692 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001257345 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133117 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133118 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AFJ59921 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073645
  ENSRNOP00000073645.1
RefSeq Acc Id: NP_001257345   ⟸   NM_001270416
- UniProtKB: A0A0G2K622 (UniProtKB/TrEMBL),   I2C088 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073645   ⟸   ENSRNOT00000088432
RefSeq Acc Id: XP_063133117   ⟸   XM_063277047
- Peptide Label: isoform X1
- UniProtKB: I2C088 (UniProtKB/TrEMBL),   A0A0G2K622 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133118   ⟸   XM_063277048
- Peptide Label: isoform X2
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K622-F1-model_v2 AlphaFold A0A0G2K622 1-169 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323347 AgrOrtholog
BioCyc Gene G2FUF-7948 BioCyc
Ensembl Genes ENSRNOG00000052628 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088432 ENTREZGENE
  ENSRNOT00000088432.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.1120 UniProtKB/TrEMBL
InterPro SLBP1/SLBP2 UniProtKB/TrEMBL
  SLBP_RNA_bind UniProtKB/TrEMBL
  SLBP_RNA_bind_sf UniProtKB/TrEMBL
KEGG Report rno:100363294 UniProtKB/TrEMBL
NCBI Gene 100363294 ENTREZGENE
PANTHER PTHR17408 UniProtKB/TrEMBL
  STEM-LOOP-BINDING PROTEIN-LIKE UniProtKB/TrEMBL
Pfam SLBP_RNA_bind UniProtKB/TrEMBL
PhenoGen Slbpl PhenoGen
RatGTEx ENSRNOG00000052628 RatGTEx
UniProt A0A0G2K622 ENTREZGENE, UniProtKB/TrEMBL
  I2C088 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Slbpl  stem-loop binding protein like  LOC100363294  stem-loop binding protein-like  Symbol and Name Changed 1299863 APPROVED
2010-05-06 LOC100363294  stem-loop binding protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL