(+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of CDKN2A mRNA CTD PMID:17971868 (+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of CDKN2A mRNA CTD PMID:17971868 (-)-epigallocatechin 3-gallate decreases metabolic processing ISO RGD:737039 6480464 epigallocatechin gallate results in decreased metabolism of CDKN2A promoter CTD PMID:16037419 (-)-epigallocatechin 3-gallate increases expression ISO RGD:737039 6480464 epigallocatechin gallate results in increased expression of CDKN2A mRNA, epigallocatechin gallate results in increased expression of CDKN2A protein CTD PMID:14633667 , PMID:17683969 (-)-epigallocatechin 3-gallate decreases methylation ISO RGD:737039 6480464 epigallocatechin gallate results in decreased methylation of CDKN2A gene, epigallocatechin gallate results in decreased methylation of CDKN2A promoter CTD PMID:14633667 , PMID:17683969 (S)-naringenin multiple interactions ISO RGD:737039 6480464 [naringenin co-treated with bisphenol A] results in increased expression of CDKN2A mRNA CTD PMID:36235125 (S)-nicotine multiple interactions ISO RGD:10322 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A mRNA] more ... CTD PMID:32473187 (S)-nicotine increases expression ISO RGD:10322 6480464 Nicotine results in increased expression of CDKN2A mRNA, Nicotine results in increased expression of CDKN2A protein CTD PMID:32473187 (Z)-3-butylidenephthalide increases expression ISO RGD:737039 6480464 butylidenephthalide results in increased expression of CDKN2A protein CTD PMID:16987298 , PMID:23770345 1,2-dichloroethane decreases expression ISO RGD:10322 6480464 ethylene dichloride results in decreased expression of CDKN2A mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO RGD:10322 6480464 [NFE2L2 protein affects the susceptibility to 1 more ... CTD PMID:26388957 1,2-dimethylhydrazine increases expression ISO RGD:10322 6480464 1 more ... CTD PMID:26388957 17beta-estradiol decreases expression ISO RGD:737039 6480464 Estradiol results in decreased expression of CDKN2A mRNA CTD PMID:19027819 , PMID:23094148 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:737039 6480464 Metribolone results in increased expression of CDKN2A protein CTD PMID:23272087 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10322 6480464 Tetrachlorodibenzodioxin results in increased expression of CDKN2A mRNA CTD PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737039 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDKN2A mRNA, Tetrachlorodibenzodioxin results in decreased expression of CDKN2A protein CTD PMID:17070097 , PMID:17257637 2,3,7,8-tetrachlorodibenzodioxine increases methylation EXP 6480464 Tetrachlorodibenzodioxin results in increased methylation of CDKN2A promoter alternative form CTD PMID:26431795 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CDKN2A mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10322 6480464 [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A mRNA, [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A protein CTD PMID:21167638 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CDKN2A mRNA CTD PMID:21346803 2-acetamidofluorene multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA, [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A protein CTD PMID:16317707 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of CDKN2A mRNA CTD PMID:19167416 , PMID:22213190 2-acetamidofluorene increases methylation EXP 6480464 2-Acetylaminofluorene results in increased methylation of CDKN2A gene, 2-Acetylaminofluorene results in increased methylation of CDKN2A promoter CTD PMID:18204080 , PMID:20188851 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin analog results in increased expression of CDKN2A protein, alpha-Chlorohydrin results in increased expression of CDKN2A protein CTD PMID:26072098 4,4'-sulfonyldiphenol increases expression ISO RGD:10322 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CDKN2A mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol increases expression ISO RGD:737039 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CDKN2A mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of CDKN2A protein CTD PMID:36565802 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:10322 6480464 [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A mRNA, [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A protein CTD PMID:21167638 4-hydroxyphenyl retinamide increases expression ISO RGD:737039 6480464 Fenretinide results in increased expression of CDKN2A protein CTD PMID:16570282 4-phenylbutyric acid multiple interactions ISO RGD:737039 6480464 [4-phenylbutyric acid co-treated with decitabine] results in increased expression of CDKN2A mRNA CTD PMID:17210717 4-vinylcyclohexene dioxide increases expression ISO RGD:10322 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of CDKN2A mRNA CTD PMID:20829426 5-aza-2'-deoxycytidine multiple interactions ISO RGD:737039 6480464 [4-phenylbutyric acid co-treated with Decitabine] results in increased expression of CDKN2A mRNA more ... CTD PMID:16613325 more ... 5-aza-2'-deoxycytidine decreases methylation ISO RGD:737039 6480464 Decitabine results in decreased methylation of CDKN2A gene more ... CTD PMID:12859993 more ... 5-aza-2'-deoxycytidine increases phosphorylation ISO RGD:737039 6480464 Decitabine results in increased phosphorylation of CDKN2A protein CTD PMID:19732952 5-aza-2'-deoxycytidine increases expression ISO RGD:10322 6480464 Decitabine results in increased expression of CDKN2A mRNA CTD PMID:27915011 5-aza-2'-deoxycytidine decreases expression ISO RGD:737039 6480464 Decitabine results in decreased expression of CDKN2A mRNA CTD PMID:19027819 5-aza-2'-deoxycytidine increases expression ISO RGD:737039 6480464 Decitabine results in increased expression of CDKN2A mRNA more ... CTD PMID:12859993 more ... 5-aza-2'-deoxycytidine affects expression ISO RGD:737039 6480464 Decitabine affects the expression of CDKN2A mRNA CTD PMID:17194187 5-aza-2'-deoxycytidine affects methylation ISO RGD:737039 6480464 [Decitabine affects the methylation of H3-4 protein] which affects the methylation of CDKN2A gene, Decitabine affects the methylation of CDKN2A promoter CTD PMID:17571247 more ... 5-azacytidine multiple interactions EXP 6480464 [Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene, [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA CTD PMID:21224363 5-azacytidine multiple interactions ISO RGD:10322 6480464 Azacitidine inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter] CTD PMID:22355787 5-azacytidine multiple interactions ISO RGD:737039 6480464 Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene] CTD PMID:17686055 5-azacytidine decreases methylation ISO RGD:737039 6480464 Azacitidine results in decreased methylation of CDKN2A gene CTD PMID:17686055 5-azacytidine affects methylation ISO RGD:737039 6480464 Azacitidine affects the methylation of CDKN2A gene CTD PMID:18443271 5-azacytidine increases expression EXP 6480464 Azacitidine results in increased expression of CDKN2A mRNA CTD PMID:21224363 5-azacytidine decreases methylation EXP 6480464 Azacitidine results in decreased methylation of CDKN2A gene CTD PMID:21224363 5-fluorouracil decreases expression ISO RGD:737039 6480464 Fluorouracil results in decreased expression of CDKN2A protein CTD PMID:17982676 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CDKN2A mRNA CTD PMID:22504374 , PMID:24780913 7,12-dimethyltetraphene increases response to substance ISO RGD:10322 6480464 CDKN2A gene polymorphism results in increased susceptibility to 9 more ... CTD PMID:11544531 7,12-dimethyltetraphene decreases expression ISO RGD:10322 6480464 9 more ... CTD PMID:24792773 7,12-dimethyltetraphene multiple interactions ISO RGD:10322 6480464 Butyric Acid inhibits the reaction [9 more ... CTD PMID:24792773 7,12-dimethyltetraphene increases methylation ISO RGD:10322 6480464 9 more ... CTD PMID:24792773 aflatoxin B1 decreases methylation ISO RGD:737039 6480464 Aflatoxin B1 results in decreased methylation of CDKN2A gene CTD PMID:27153756 aflatoxin B1 increases expression ISO RGD:737039 6480464 Aflatoxin B1 results in increased expression of CDKN2A mRNA CTD PMID:28965971 agomelatine multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of CDKN2A protein] CTD PMID:34673010 aldehydo-D-glucose multiple interactions ISO RGD:737039 6480464 SIRT3 protein inhibits the reaction [Glucose results in increased expression of CDKN2A protein alternative form] CTD PMID:23494737 aldehydo-D-glucose increases expression ISO RGD:737039 6480464 Glucose results in increased expression of CDKN2A protein alternative form CTD PMID:23494737 all-trans-retinoic acid decreases expression ISO RGD:737039 6480464 Tretinoin results in decreased expression of CDKN2A mRNA CTD PMID:16494909 all-trans-retinoic acid increases expression ISO RGD:737039 6480464 Tretinoin results in increased expression of CDKN2A mRNA CTD PMID:17138961 alpha-D-galactose multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of CDKN2A protein], Melatonin inhibits the reaction [Galactose results in increased expression of CDKN2A protein] CTD PMID:34673010 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of CDKN2A protein CTD PMID:34673010 ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of CDKN2A protein CTD PMID:16483693 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CDKN2A mRNA CTD PMID:16483693 amosite asbestos decreases expression ISO RGD:10322 6480464 Asbestos more ... CTD PMID:29112861 amosite asbestos increases methylation ISO RGD:10322 6480464 Asbestos, Amosite results in increased methylation of CDKN2A exon CTD PMID:29112861 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:10322 6480464 pyrazolanthrone inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter] CTD PMID:22355787 aristolochic acid A increases expression ISO RGD:737039 6480464 aristolochic acid I results in increased expression of CDKN2A mRNA CTD PMID:33212167 arsane decreases expression ISO RGD:10322 6480464 Arsenic results in decreased expression of CDKN2A mRNA, Arsenic results in decreased expression of CDKN2A protein CTD PMID:22843710 arsane increases expression ISO RGD:737039 6480464 Arsenic results in increased expression of CDKN2A mRNA CTD PMID:12773770 arsane affects expression ISO RGD:737039 6480464 Arsenic affects the expression of CDKN2A protein CTD PMID:17450239 arsane increases methylation ISO RGD:737039 6480464 Arsenic results in increased methylation of CDKN2A gene more ... CTD PMID:16251483 more ... arsane decreases expression ISO RGD:737039 6480464 Arsenic results in decreased expression of CDKN2A mRNA CTD PMID:23872714 arsane multiple interactions ISO RGD:10322 6480464 BMI1 protein promotes the reaction [Arsenic results in decreased expression of CDKN2A mRNA] more ... CTD PMID:22843710 arsenic atom decreases expression ISO RGD:10322 6480464 Arsenic results in decreased expression of CDKN2A mRNA, Arsenic results in decreased expression of CDKN2A protein CTD PMID:22843710 arsenic atom increases expression ISO RGD:737039 6480464 Arsenic results in increased expression of CDKN2A mRNA CTD PMID:12773770 arsenic atom affects expression ISO RGD:737039 6480464 Arsenic affects the expression of CDKN2A protein CTD PMID:17450239 arsenic atom increases methylation ISO RGD:737039 6480464 Arsenic results in increased methylation of CDKN2A gene more ... CTD PMID:16251483 more ... arsenic atom decreases expression ISO RGD:737039 6480464 Arsenic results in decreased expression of CDKN2A mRNA CTD PMID:23872714 arsenic atom multiple interactions ISO RGD:10322 6480464 BMI1 protein promotes the reaction [Arsenic results in decreased expression of CDKN2A mRNA] more ... CTD PMID:22843710 arsenite(3-) increases expression ISO RGD:10322 6480464 arsenite results in increased expression of CDKN2A mRNA CTD PMID:33010264 arsenite(3-) multiple interactions ISO RGD:737039 6480464 arsenite promotes the reaction [G3BP1 protein binds to CDKN2A mRNA] more ... CTD PMID:21040761 , PMID:32406909 arsenite(3-) decreases methylation ISO RGD:737039 6480464 arsenite results in decreased methylation of CDKN2A promoter CTD PMID:23974009 arsenite(3-) decreases expression ISO RGD:737039 6480464 arsenite results in decreased expression of CDKN2A mRNA, arsenite results in decreased expression of CDKN2A protein CTD PMID:21040761 arsenite(3-) increases methylation ISO RGD:737039 6480464 arsenite results in increased methylation of CDKN2A gene CTD PMID:21040761 arsenous acid multiple interactions ISO RGD:737039 6480464 [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA more ... CTD PMID:16613325 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CDKN2A protein CTD PMID:31734849 arsenous acid increases expression ISO RGD:737039 6480464 Arsenic Trioxide results in increased expression of CDKN2A gene more ... CTD PMID:12864950 more ... arsenous acid decreases methylation ISO RGD:737039 6480464 Arsenic Trioxide results in decreased methylation of CDKN2A gene, Arsenic Trioxide results in decreased methylation of CDKN2A promoter CTD PMID:15191659 more ... asbestos decreases expression ISO RGD:737039 6480464 Asbestos results in decreased expression of CDKN2A mRNA CTD PMID:22076105 asbestos increases mutagenesis ISO RGD:737039 6480464 Asbestos results in increased mutagenesis of CDKN2A gene CTD PMID:19375815 asbestos increases methylation ISO RGD:737039 6480464 Asbestos results in increased methylation of CDKN2A promoter CTD PMID:15911247 belinostat decreases expression ISO RGD:737039 6480464 belinostat results in decreased expression of CDKN2A mRNA CTD PMID:19606018 benzene affects response to substance ISO RGD:737039 6480464 CDKN2A gene polymorphism affects the susceptibility to Benzene CTD PMID:19596022 benzene decreases expression ISO RGD:737039 6480464 Benzene results in decreased expression of CDKN2A mRNA CTD PMID:20044985 benzene multiple interactions ISO RGD:737039 6480464 [Benzene results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA, MDM2 gene polymorphism affects the reaction [CDKN2A gene polymorphism affects the susceptibility to Benzene] CTD PMID:19596022 , PMID:20044985 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of CDKN2A mRNA, Benzo(a)pyrene results in decreased expression of CDKN2A protein CTD PMID:19408242 more ... benzo[a]pyrene multiple interactions ISO RGD:737039 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN2A mRNA], AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CDKN2A mRNA] CTD PMID:35182551 benzo[a]pyrene increases expression ISO RGD:737039 6480464 Benzo(a)pyrene results in increased expression of CDKN2A mRNA CTD PMID:35182551 benzo[a]pyrene increases mutagenesis ISO RGD:737039 6480464 Benzo(a)pyrene results in increased mutagenesis of CDKN2A gene CTD PMID:25435355 benzo[a]pyrene multiple interactions ISO RGD:10322 6480464 [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CDKN2A mRNA, Benzo(a)pyrene affects the reaction [sodium bichromate results in decreased expression of CDKN2A mRNA] CTD PMID:22613061 , PMID:25820237 benzo[a]pyrene multiple interactions EXP 6480464 [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA more ... CTD PMID:19408242 , PMID:20064080 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CDKN2A protein CTD PMID:19408242 benzo[b]fluoranthene decreases expression ISO RGD:10322 6480464 benzo(b)fluoranthene results in decreased expression of CDKN2A mRNA CTD PMID:26377693 beryllium atom multiple interactions EXP 6480464 [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 beryllium dihydride multiple interactions EXP 6480464 [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 beryllium sulfate increases expression ISO RGD:737039 6480464 beryllium sulfate results in increased expression of CDKN2A mRNA, beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 beryllium(0) multiple interactions EXP 6480464 [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 bis(2-chloroethyl) sulfide increases expression ISO RGD:737039 6480464 Mustard Gas results in increased expression of CDKN2A mRNA, Mustard Gas results in increased expression of CDKN2A protein CTD PMID:33491125 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:10322 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:28013214 bis(2-ethylhexyl) phthalate affects expression ISO RGD:10322 6480464 Diethylhexyl Phthalate affects the expression of CDKN2A mRNA CTD PMID:31211961 bis(2-ethylhexyl) phthalate increases expression ISO RGD:737039 6480464 Diethylhexyl Phthalate results in increased expression of CDKN2A mRNA CTD PMID:31163220 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CDKN2A mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:737039 6480464 [naringenin co-treated with bisphenol A] results in increased expression of CDKN2A mRNA CTD PMID:36235125 bisphenol A decreases expression ISO RGD:737039 6480464 bisphenol A results in decreased expression of CDKN2A mRNA CTD PMID:31610501 bisphenol A increases expression ISO RGD:10322 6480464 bisphenol A results in increased expression of CDKN2A mRNA CTD PMID:30951980 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of CDKN2A gene CTD PMID:28505145 bisphenol A increases methylation ISO RGD:737039 6480464 bisphenol A results in increased methylation of CDKN2A gene, bisphenol A results in increased methylation of CDKN2A promoter CTD PMID:22258036 , PMID:31610501 bisphenol A increases expression ISO RGD:737039 6480464 bisphenol A results in increased expression of CDKN2A protein CTD PMID:22258036 bisphenol F increases expression ISO RGD:10322 6480464 bisphenol F results in increased expression of CDKN2A mRNA CTD PMID:30951980 BMS-754807 decreases response to substance ISO RGD:737039 6480464 CDKN2A gene mutant form results in decreased susceptibility to BMS 754807 CTD PMID:24986516 busulfan increases expression ISO RGD:10322 6480464 Busulfan results in increased expression of CDKN2A mRNA CTD PMID:14500376 Butylbenzyl phthalate multiple interactions ISO RGD:10322 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:28013214 Butylbenzyl phthalate increases methylation ISO RGD:737039 6480464 butylbenzyl phthalate results in increased methylation of CDKN2A promoter CTD PMID:35487445 Butylbenzyl phthalate decreases expression ISO RGD:737039 6480464 butylbenzyl phthalate results in decreased expression of CDKN2A mRNA CTD PMID:35487445 butyric acid multiple interactions ISO RGD:10322 6480464 Butyric Acid inhibits the reaction [9 more ... CTD PMID:24792773 C60 fullerene increases expression ISO RGD:737039 6480464 fullerene C60 analog results in increased expression of CDKN2A protein CTD PMID:20045429 cadmium atom increases methylation ISO RGD:737039 6480464 Cadmium results in increased methylation of CDKN2A promoter CTD PMID:17938735 cadmium dichloride increases methylation ISO RGD:737039 6480464 Cadmium Chloride results in increased methylation of CDKN2A promoter alternative form CTD PMID:25448810 cadmium dichloride decreases expression ISO RGD:737039 6480464 Cadmium Chloride results in decreased expression of CDKN2A mRNA alternative form, Cadmium Chloride results in decreased expression of CDKN2A protein CTD PMID:17938735 more ... cadmium dichloride multiple interactions ISO RGD:737039 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of CDKN2A mRNA more ... CTD PMID:12634122 more ... cadmium dichloride decreases response to substance ISO RGD:737039 6480464 CDKN2A results in decreased susceptibility to Cadmium Chloride CTD PMID:25448810 calcium dichloride multiple interactions EXP 6480464 Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA], Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A protein] CTD PMID:12189186 cannabidiol increases expression ISO RGD:10322 6480464 Cannabidiol results in increased expression of CDKN2A mRNA CTD PMID:21542829 cannabidiol increases expression ISO RGD:737039 6480464 Cannabidiol results in increased expression of CDKN2A mRNA, Cannabidiol results in increased expression of CDKN2A protein CTD PMID:36519830 cannabidiol multiple interactions ISO RGD:737039 6480464 Cannabidiol promotes the reaction [[Oxygen co-treated with Ozone] results in increased expression of CDKN2A mRNA] CTD PMID:32992648 cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of CDKN2A mRNA CTD PMID:32553926 capecitabine decreases expression ISO RGD:737039 6480464 Capecitabine results in decreased expression of CDKN2A protein CTD PMID:17904787 capsaicin increases expression ISO RGD:737039 6480464 Capsaicin results in increased expression of CDKN2A mRNA CTD PMID:18533110 carbon nanotube decreases expression ISO RGD:10322 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:29112861 carbon nanotube increases methylation ISO RGD:10322 6480464 Nanotubes, Carbon results in increased methylation of CDKN2A exon CTD PMID:29112861 carbon nanotube increases mutagenesis ISO RGD:10322 6480464 Nanotubes, Carbon results in increased mutagenesis of CDKN2A gene alternative form CTD PMID:29112861 carbon nanotube decreases expression ISO RGD:737039 6480464 Nanotubes, Carbon results in decreased expression of CDKN2A mRNA CTD PMID:22076105 carbon nanotube increases expression ISO RGD:737039 6480464 Nanotubes, Carbon results in increased expression of CDKN2A mRNA CTD PMID:15585362 , PMID:23634900 carmustine increases response to substance ISO RGD:737039 6480464 CDKN2A protein results in increased susceptibility to Carmustine CTD PMID:16786135 casticin increases expression ISO RGD:737039 6480464 casticin results in increased expression of CDKN2A protein CTD PMID:29098808 chloramphenicol increases expression ISO RGD:737039 6480464 Chloramphenicol results in increased expression of CDKN2A protein CTD PMID:15905168 chloroethene affects response to substance ISO RGD:737039 6480464 CDKN2A polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 chromium atom affects methylation ISO RGD:737039 6480464 Chromium affects the methylation of CDKN2A protein CTD PMID:16828922 chromium atom decreases expression ISO RGD:737039 6480464 Chromium results in decreased expression of CDKN2A protein CTD PMID:16828922 chromium(6+) multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CDKN2A protein] CTD PMID:21621607 chromium(6+) increases expression ISO RGD:737039 6480464 chromium hexavalent ion results in increased expression of CDKN2A mRNA CTD PMID:23940686 chromium(6+) multiple interactions ISO RGD:10322 6480464 [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CDKN2A mRNA CTD PMID:25820237 chromium(6+) increases expression EXP 6480464 chromium hexavalent ion results in increased expression of CDKN2A protein CTD PMID:21621607 chymostatin multiple interactions ISO RGD:737039 6480464 chymostatin inhibits the reaction [KRAS protein mutant form results in increased expression of CDKN2A protein] CTD PMID:33380422 cisplatin increases expression ISO RGD:737039 6480464 Cisplatin results in increased expression of CDKN2A mRNA, Cisplatin results in increased expression of CDKN2A protein CTD PMID:16797627 , PMID:20540955 cisplatin multiple interactions ISO RGD:737039 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CDKN2A mRNA, [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of CDKN2A mRNA CTD PMID:27514524 , PMID:30871063 cisplatin decreases expression ISO RGD:737039 6480464 Cisplatin results in decreased expression of CDKN2A protein CTD PMID:16797627 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDKN2A mRNA CTD PMID:17602206 copper atom decreases expression ISO RGD:737039 6480464 Copper results in decreased expression of CDKN2A protein CTD PMID:16246896 copper atom multiple interactions ISO RGD:737039 6480464 [Chelating Agents binds to Copper] which results in decreased expression of CDKN2A mRNA, [Copper results in increased activity of TP53 protein] which results in increased expression of CDKN2A mRNA CTD PMID:16391388 , PMID:30911355 copper(0) decreases expression ISO RGD:737039 6480464 Copper results in decreased expression of CDKN2A protein CTD PMID:16246896 copper(0) multiple interactions ISO RGD:737039 6480464 [Chelating Agents binds to Copper] which results in decreased expression of CDKN2A mRNA, [Copper results in increased activity of TP53 protein] which results in increased expression of CDKN2A mRNA CTD PMID:16391388 , PMID:30911355 copper(II) sulfate increases expression ISO RGD:737039 6480464 Copper Sulfate results in increased expression of CDKN2A mRNA CTD PMID:19549813 cordycepin multiple interactions EXP 6480464 cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA] CTD PMID:23690541 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of CDKN2A mRNA CTD PMID:15755911 crocidolite asbestos increases response to substance ISO RGD:10322 6480464 CDKN2A gene mutant form results in increased susceptibility to Asbestos, Crocidolite CTD PMID:21526190 crocidolite asbestos decreases expression ISO RGD:737039 6480464 Asbestos more ... CTD PMID:21570478 crocidolite asbestos multiple interactions ISO RGD:10322 6480464 [CDKN2A mRNA alternative form affects the susceptibility to Asbestos, Crocidolite] which affects the expression of FAF1 mRNA CTD PMID:19223589 crocidolite asbestos affects response to substance ISO RGD:10322 6480464 CDKN2A mRNA alternative form affects the susceptibility to Asbestos, Crocidolite CTD PMID:19223589 crocidolite asbestos increases mutagenesis ISO RGD:10322 6480464 Asbestos, Crocidolite results in increased mutagenesis of CDKN2A gene alternative form CTD PMID:19223589 crocidolite asbestos decreases expression ISO RGD:10322 6480464 Asbestos more ... CTD PMID:19223589 curcumin decreases expression ISO RGD:737039 6480464 Curcumin results in decreased expression of CDKN2A protein CTD PMID:17148446 curcumin increases expression ISO RGD:737039 6480464 Curcumin results in increased expression of CDKN2A protein CTD PMID:18156803 cycloheximide increases expression ISO RGD:737039 6480464 Cycloheximide results in increased expression of CDKN2A mRNA CTD PMID:17257637 cypermethrin increases expression ISO RGD:737039 6480464 cypermethrin results in increased expression of CDKN2A mRNA CTD PMID:36063984 D-glucose multiple interactions ISO RGD:737039 6480464 SIRT3 protein inhibits the reaction [Glucose results in increased expression of CDKN2A protein alternative form] CTD PMID:23494737 D-glucose increases expression ISO RGD:737039 6480464 Glucose results in increased expression of CDKN2A protein alternative form CTD PMID:23494737 daunorubicin affects expression ISO RGD:737039 6480464 Daunorubicin affects the expression of CDKN2A mRNA CTD PMID:12656675 DDT decreases expression EXP 6480464 DDT results in decreased expression of CDKN2A mRNA alternative form, DDT results in decreased expression of CDKN2A protein alternative form CTD PMID:25410620 DDT increases methylation EXP 6480464 DDT results in increased methylation of CDKN2A promoter alternative form CTD PMID:25410620 dehydroepiandrosterone increases expression EXP 6480464 Dehydroepiandrosterone results in increased expression of CDKN2A protein CTD PMID:16457693 Deoxycorticosterone acetate multiple interactions EXP 6480464 [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein] more ... CTD PMID:18504326 Deoxycorticosterone acetate affects localization EXP 6480464 Desoxycorticosterone Acetate affects the localization of CDKN2A protein CTD PMID:18504326 Deoxycorticosterone acetate increases expression EXP 6480464 Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA, Desoxycorticosterone Acetate results in increased expression of CDKN2A protein CTD PMID:18504326 Diacetoxyscirpenol decreases expression ISO RGD:10322 6480464 diacetoxyscirpenol results in decreased expression of CDKN2A mRNA CTD PMID:31836554 diarsenic trioxide multiple interactions ISO RGD:737039 6480464 [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA more ... CTD PMID:16613325 more ... diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CDKN2A protein CTD PMID:31734849 diarsenic trioxide decreases methylation ISO RGD:737039 6480464 Arsenic Trioxide results in decreased methylation of CDKN2A gene, Arsenic Trioxide results in decreased methylation of CDKN2A promoter CTD PMID:15191659 more ... diarsenic trioxide increases expression ISO RGD:737039 6480464 Arsenic Trioxide results in increased expression of CDKN2A gene more ... CTD PMID:12864950 more ... dibutyl phthalate multiple interactions ISO RGD:10322 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:28013214 dibutyl phthalate increases methylation ISO RGD:737039 6480464 Dibutyl Phthalate results in increased methylation of CDKN2A promoter CTD PMID:35487445 dibutyl phthalate decreases expression ISO RGD:737039 6480464 Dibutyl Phthalate results in decreased expression of CDKN2A mRNA CTD PMID:35487445 dichloroacetic acid increases expression ISO RGD:10322 6480464 Dichloroacetic Acid results in increased expression of CDKN2A mRNA CTD PMID:28962523 dichromic acid increases methylation ISO RGD:737039 6480464 chromic acid results in increased methylation of CDKN2A gene CTD PMID:27005777 dichromic acid decreases expression ISO RGD:737039 6480464 chromic acid results in decreased expression of CDKN2A mRNA CTD PMID:27005777 dichromium trioxide multiple interactions ISO RGD:737039 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of CDKN2A mRNA CTD PMID:12634122 diethyl phthalate multiple interactions ISO RGD:10322 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:28013214 diisobutyl phthalate multiple interactions ISO RGD:10322 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:28013214 diisononyl phthalate multiple interactions ISO RGD:10322 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:28013214 dimethylarsinic acid decreases expression EXP 6480464 Cacodylic Acid results in decreased expression of CDKN2A mRNA CTD PMID:16122865 dimethylarsinic acid decreases methylation ISO RGD:737039 6480464 Cacodylic Acid results in decreased methylation of CDKN2A promoter alternative form CTD PMID:23073540 dioscin increases expression ISO RGD:737039 6480464 dioscin results in increased expression of CDKN2A mRNA, dioscin results in increased expression of CDKN2A protein CTD PMID:33359023 dioxygen multiple interactions ISO RGD:737039 6480464 [Oxygen co-treated with Ozone] results in increased expression of CDKN2A mRNA, Cannabidiol promotes the reaction [[Oxygen co-treated with Ozone] results in increased expression of CDKN2A mRNA] CTD PMID:32992648 disodium selenite increases expression ISO RGD:737039 6480464 Sodium Selenite results in increased expression of CDKN2A protein CTD PMID:25204997 dorsomorphin multiple interactions ISO RGD:737039 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CDKN2A mRNA more ... CTD PMID:24902966 more ... doxorubicin increases expression ISO RGD:10322 6480464 Doxorubicin results in increased expression of CDKN2A mRNA CTD PMID:34713381 doxorubicin increases expression ISO RGD:737039 6480464 Doxorubicin results in increased expression of CDKN2A mRNA CTD PMID:16705698 doxorubicin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [Doxorubicin results in increased expression of CDKN2A protein] more ... CTD PMID:24902966 , PMID:33484087 entinostat multiple interactions EXP 6480464 [Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene, [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA CTD PMID:21224363 ethanol multiple interactions ISO RGD:10322 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]] more ... CTD PMID:34192554 , PMID:34405320 ethanol increases expression ISO RGD:737039 6480464 Ethanol results in increased expression of CDKN2A mRNA, Ethanol results in increased expression of CDKN2A protein CTD PMID:34192554 , PMID:34405320 ethanol multiple interactions ISO RGD:737039 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]] more ... CTD PMID:34192554 , PMID:34405320 ethanol increases expression ISO RGD:10322 6480464 Ethanol results in increased expression of CDKN2A mRNA, Ethanol results in increased expression of CDKN2A protein CTD PMID:34192554 , PMID:34405320 etoposide multiple interactions ISO RGD:10322 6480464 [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein], [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein] CTD PMID:21526190 etoposide increases expression EXP 6480464 Etoposide results in increased expression of CDKN2A mRNA CTD PMID:23690541 etoposide multiple interactions EXP 6480464 cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA] more ... CTD PMID:23690541 farrerol increases expression ISO RGD:737039 6480464 farrerol results in increased expression of CDKN2A mRNA, farrerol results in increased expression of CDKN2A protein CTD PMID:35833306 fenbendazole increases methylation EXP 6480464 Fenbendazole results in increased methylation of CDKN2A gene CTD PMID:22659510 fenbendazole increases expression EXP 6480464 Fenbendazole results in increased expression of CDKN2A protein CTD PMID:23411599 fenbendazole decreases expression EXP 6480464 Fenbendazole results in decreased expression of CDKN2A protein CTD PMID:22659510 ferric oxide decreases expression ISO RGD:10322 6480464 ferric oxide analog results in decreased expression of CDKN2A mRNA CTD PMID:24525745 ferrostatin-1 multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN2A protein] CTD PMID:33737050 fluoxetine increases expression ISO RGD:10322 6480464 Fluoxetine results in increased expression of CDKN2A mRNA CTD PMID:21497159 folic acid affects methylation ISO RGD:10322 6480464 Folic Acid affects the methylation of CDKN2A promoter CTD PMID:17585020 folic acid affects methylation ISO RGD:737039 6480464 Folic Acid affects the methylation of CDKN2A promoter CTD PMID:16646054 folic acid multiple interactions ISO RGD:737039 6480464 MTHFR gene polymorphism affects the reaction [Folic Acid affects the methylation of CDKN2A promoter] CTD PMID:16646054 folic acid affects expression ISO RGD:10322 6480464 Folic Acid affects the expression of CDKN2A mRNA CTD PMID:17585020 fumonisin B1 increases expression ISO RGD:10322 6480464 fumonisin B1 results in increased expression of CDKN2A mRNA CTD PMID:16221962 furan increases expression EXP 6480464 furan results in increased expression of CDKN2A mRNA CTD PMID:20562052 , PMID:22079235 galactose increases expression EXP 6480464 Galactose results in increased expression of CDKN2A protein CTD PMID:34673010 galactose multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of CDKN2A protein], Melatonin inhibits the reaction [Galactose results in increased expression of CDKN2A protein] CTD PMID:34673010 gamma-tocopherol decreases expression ISO RGD:737039 6480464 gamma-Tocopherol results in decreased expression of CDKN2A protein CTD PMID:12368234 glucaric acid multiple interactions ISO RGD:10322 6480464 Glucaric Acid inhibits the reaction [9 more ... CTD PMID:24792773 glucose multiple interactions ISO RGD:737039 6480464 SIRT3 protein inhibits the reaction [Glucose results in increased expression of CDKN2A protein alternative form] CTD PMID:23494737 glucose increases expression ISO RGD:737039 6480464 Glucose results in increased expression of CDKN2A protein alternative form CTD PMID:23494737 glycidol increases expression EXP 6480464 glycidol results in increased expression of CDKN2A mRNA CTD PMID:24915197 glycine betaine multiple interactions EXP 6480464 Betaine promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA] CTD PMID:19642983 glyphosate decreases expression ISO RGD:737039 6480464 glyphosate results in decreased expression of CDKN2A mRNA CTD PMID:31751608 GW 3965 increases expression ISO RGD:737039 6480464 GW 3965 results in increased expression of CDKN2A mRNA CTD PMID:31437187 harmine decreases expression ISO RGD:737039 6480464 Harmine results in decreased expression of CDKN2A mRNA, Harmine results in decreased expression of CDKN2A protein CTD PMID:25751815 hexachlorobenzene increases methylation EXP 6480464 Hexachlorobenzene results in increased methylation of CDKN2A promoter alternative form CTD PMID:26431795 hydralazine multiple interactions EXP 6480464 [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein], [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 hydralazine decreases methylation ISO RGD:737039 6480464 Hydralazine results in decreased methylation of CDKN2A promoter CTD PMID:15862127 hydrochlorothiazide multiple interactions EXP 6480464 [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein], [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 hydrogen peroxide affects expression ISO RGD:737039 6480464 Hydrogen Peroxide affects the expression of CDKN2A protein CTD PMID:21179406 hydrogen peroxide multiple interactions ISO RGD:737039 6480464 Hydrogen Peroxide promotes the reaction [MAPT results in increased expression of CDKN2A protein] CTD PMID:28526263 hydroquinone multiple interactions ISO RGD:737039 6480464 CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein] more ... CTD PMID:33771647 , PMID:33932074 hydroquinone decreases expression ISO RGD:737039 6480464 hydroquinone results in decreased expression of CDKN2A mRNA, hydroquinone results in decreased expression of CDKN2A protein CTD PMID:33771647 , PMID:33932074 hydroxyurea multiple interactions ISO RGD:737039 6480464 Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene], Hydroxyurea inhibits the reaction [decitabine results in decreased methylation of CDKN2A gene] CTD PMID:17686055 hydroxyurea increases expression ISO RGD:737039 6480464 Hydroxyurea results in increased expression of CDKN2A protein CTD PMID:10961388 imidacloprid affects methylation ISO RGD:10322 6480464 imidacloprid affects the methylation of CDKN2A promoter CTD PMID:33865946 imidacloprid multiple interactions ISO RGD:10322 6480464 LIF protein affects the reaction [imidacloprid affects the methylation of CDKN2A promoter] CTD PMID:33865946 irbesartan multiple interactions ISO RGD:10322 6480464 Irbesartan inhibits the reaction [KRAS protein mutant form results in increased expression of CDKN2A protein] CTD PMID:33380422 irinotecan affects expression ISO RGD:737039 6480464 Irinotecan affects the expression of CDKN2A protein CTD PMID:22898888 irinotecan increases response to substance ISO RGD:737039 6480464 CDKN2A results in increased susceptibility to Irinotecan CTD PMID:22898888 irinotecan decreases expression ISO RGD:737039 6480464 Irinotecan results in decreased expression of CDKN2A mRNA CTD PMID:16432164 isocyanates increases expression ISO RGD:10322 6480464 Isocyanates results in increased expression of CDKN2A protein CTD PMID:20685613 ivermectin decreases expression ISO RGD:737039 6480464 Ivermectin results in decreased expression of CDKN2A protein CTD PMID:32959892 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CDKN2A protein] CTD PMID:21621607 lead diacetate multiple interactions ISO RGD:737039 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of CDKN2A mRNA CTD PMID:12634122 lidocaine affects expression ISO RGD:10322 6480464 Lidocaine affects the expression of CDKN2A mRNA CTD PMID:18931217 linalool increases expression ISO RGD:737039 6480464 linalool results in increased expression of CDKN2A mRNA CTD PMID:26703569 lithium chloride increases expression ISO RGD:737039 6480464 Lithium Chloride results in increased expression of CDKN2A mRNA CTD PMID:23527032 losartan multiple interactions ISO RGD:737039 6480464 Losartan inhibits the reaction [KRAS protein mutant form results in increased expression of CDKN2A protein] CTD PMID:33380422 LY294002 multiple interactions ISO RGD:737039 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CDKN2A mRNA] CTD PMID:12710931 maneb increases expression EXP 6480464 Maneb results in increased expression of CDKN2A mRNA CTD PMID:29859004 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of CDKN2A mRNA CTD PMID:29859004 masoprocol decreases methylation ISO RGD:737039 6480464 Masoprocol results in decreased methylation of CDKN2A promoter CTD PMID:18164318 masoprocol increases expression ISO RGD:737039 6480464 Masoprocol results in increased expression of CDKN2A mRNA, Masoprocol results in increased expression of CDKN2A protein CTD PMID:18164318 Mecamylamine multiple interactions ISO RGD:10322 6480464 Mecamylamine inhibits the reaction [Nicotine results in increased expression of CDKN2A mRNA], Mecamylamine inhibits the reaction [Nicotine results in increased expression of CDKN2A protein] CTD PMID:32473187 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Galactose results in increased expression of CDKN2A protein] CTD PMID:34673010 menadione increases expression ISO RGD:737039 6480464 Vitamin K 3 results in increased expression of CDKN2A mRNA CTD PMID:16010434 menaquinone increases expression ISO RGD:737039 6480464 Vitamin K 2 results in increased expression of CDKN2A mRNA CTD PMID:16010434 mercury dibromide increases expression ISO RGD:737039 6480464 mercuric bromide results in increased expression of CDKN2A mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:737039 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDKN2A mRNA CTD PMID:27188386 methimazole increases expression EXP 6480464 Methimazole results in increased expression of CDKN2A mRNA CTD PMID:22504374 methoxyacetic acid increases expression ISO RGD:737039 6480464 methoxyacetic acid results in increased expression of CDKN2A protein CTD PMID:21573189 methoxyacetic acid multiple interactions ISO RGD:737039 6480464 withanone inhibits the reaction [methoxyacetic acid results in increased expression of CDKN2A protein] CTD PMID:21573189 methoxychlor increases expression ISO RGD:10322 6480464 Methoxychlor results in increased expression of CDKN2A mRNA CTD PMID:20829426 methylmercury chloride decreases expression ISO RGD:10322 6480464 methylmercuric chloride results in decreased expression of CDKN2A mRNA CTD PMID:20061341 methylmercury chloride decreases methylation EXP 6480464 methylmercuric chloride results in decreased methylation of CDKN2A promoter CTD PMID:19636072 methylseleninic acid multiple interactions ISO RGD:737039 6480464 methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein] more ... CTD PMID:17847021 methylseleninic acid increases expression ISO RGD:737039 6480464 methylselenic acid results in increased expression of CDKN2A protein CTD PMID:17847021 microcystin RR decreases expression ISO RGD:737039 6480464 microcystin RR results in decreased expression of CDKN2A protein CTD PMID:19111056 microcystin-LR decreases expression ISO RGD:737039 6480464 cyanoginosin LR results in decreased expression of CDKN2A protein CTD PMID:33474710 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:10322 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:31884101 monobenzyl phthalate multiple interactions ISO RGD:10322 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:31884101 monobenzyl phthalate increases methylation ISO RGD:737039 6480464 mono-benzyl phthalate results in increased methylation of CDKN2A promoter CTD PMID:35487445 monobenzyl phthalate decreases expression ISO RGD:737039 6480464 mono-benzyl phthalate results in decreased expression of CDKN2A mRNA CTD PMID:35487445 Monobutylphthalate increases methylation ISO RGD:737039 6480464 monobutyl phthalate results in increased methylation of CDKN2A promoter CTD PMID:35487445 Monobutylphthalate decreases expression ISO RGD:737039 6480464 monobutyl phthalate results in decreased expression of CDKN2A mRNA CTD PMID:35487445 monoethyl phthalate multiple interactions ISO RGD:10322 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA CTD PMID:31884101 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of CDKN2A mRNA, Sodium Glutamate results in decreased expression of CDKN2A protein CTD PMID:28954212 monosodium L-glutamate increases expression ISO RGD:10322 6480464 Sodium Glutamate results in increased expression of CDKN2A mRNA CTD PMID:22078008 myo-inositol hexakisphosphate multiple interactions ISO RGD:10322 6480464 Phytic Acid inhibits the reaction [Ethylnitrosourea results in decreased expression of CDKN2A] CTD PMID:21154115 myo-inositol hexakisphosphate affects methylation ISO RGD:10322 6480464 Phytic Acid affects the methylation of CDKN2A promoter CTD PMID:21154115 N-acetyl-L-cysteine multiple interactions ISO RGD:10322 6480464 Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein] more ... CTD PMID:31551408 , PMID:32473187 N-acetyl-L-cysteine multiple interactions ISO RGD:737039 6480464 Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]] more ... CTD PMID:31551408 , PMID:35303175 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO RGD:10322 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2A mRNA CTD PMID:20061341 N-ethyl-N-nitrosourea increases response to substance ISO RGD:10322 6480464 CDKN2A gene mutant form results in increased susceptibility to Ethylnitrosourea CTD PMID:17943659 N-ethyl-N-nitrosourea multiple interactions ISO RGD:10322 6480464 Phytic Acid inhibits the reaction [Ethylnitrosourea results in decreased expression of CDKN2A] CTD PMID:21154115 N-ethyl-N-nitrosourea decreases expression ISO RGD:10322 6480464 Ethylnitrosourea results in decreased expression of CDKN2A CTD PMID:21154115 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:737039 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CDKN2A mRNA] CTD PMID:12710931 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CDKN2A protein CTD PMID:33737050 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN2A protein] CTD PMID:33737050 N-nitrosodiethylamine multiple interactions ISO RGD:10322 6480464 [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA more ... CTD PMID:15082532 more ... N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of CDKN2A mRNA CTD PMID:19642983 , PMID:20360939 N-nitrosodiethylamine increases methylation EXP 6480464 Diethylnitrosamine results in increased methylation of CDKN2A promoter CTD PMID:19642983 N-nitrosodiethylamine increases expression ISO RGD:10322 6480464 Diethylnitrosamine results in increased expression of CDKN2A mRNA, Diethylnitrosamine results in increased expression of CDKN2A protein CTD PMID:19919837 , PMID:24535843 N-nitrosodiethylamine multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA more ... CTD PMID:16317707 more ... N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of CDKN2A mRNA CTD PMID:15138612 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of CDKN2A mRNA CTD PMID:22546817 nickel subsulfide decreases expression EXP 6480464 nickel subsulfide results in decreased expression of CDKN2A mRNA CTD PMID:21565688 nickel subsulfide increases methylation EXP 6480464 nickel subsulfide results in increased methylation of CDKN2A gene CTD PMID:21565688 nicotinamide multiple interactions ISO RGD:10322 6480464 Niacinamide inhibits the reaction [9 more ... CTD PMID:24792773 nicotine increases expression ISO RGD:10322 6480464 Nicotine results in increased expression of CDKN2A mRNA, Nicotine results in increased expression of CDKN2A protein CTD PMID:32473187 nicotine multiple interactions ISO RGD:10322 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A mRNA] more ... CTD PMID:32473187 nitrogen dioxide multiple interactions EXP 6480464 [Vehicle Emissions results in increased abundance of Nitrogen Dioxide] which results in increased methylation of CDKN2A gene CTD PMID:26778509 O-methyleugenol increases expression EXP 6480464 methyleugenol results in increased expression of CDKN2A protein CTD PMID:23411599 O-methyleugenol decreases expression EXP 6480464 methyleugenol results in decreased expression of CDKN2A mRNA CTD PMID:26011634 ochratoxin A increases expression ISO RGD:737039 6480464 ochratoxin A results in increased expression of CDKN2A protein CTD PMID:28286205 oxaliplatin increases expression ISO RGD:10322 6480464 Oxaliplatin results in increased expression of CDKN2A protein CTD PMID:30031110 ozone multiple interactions ISO RGD:737039 6480464 [Oxygen co-treated with Ozone] results in increased expression of CDKN2A mRNA, Cannabidiol promotes the reaction [[Oxygen co-treated with Ozone] results in increased expression of CDKN2A mRNA] CTD PMID:32992648 p-menthan-3-ol increases expression ISO RGD:737039 6480464 Menthol results in increased expression of CDKN2A mRNA CTD PMID:26760959 palbociclib affects response to substance ISO RGD:737039 6480464 CDKN2A gene modified form affects the susceptibility to palbociclib more ... CTD PMID:24495407 palbociclib decreases response to substance ISO RGD:737039 6480464 CDKN2A protein results in decreased susceptibility to palbociclib CTD PMID:21278246 , PMID:22711607 palbociclib increases response to substance ISO RGD:10322 6480464 CDKN2A gene mutant form results in increased susceptibility to palbociclib CTD PMID:24098593 palbociclib multiple interactions ISO RGD:10322 6480464 [CDKN2A gene mutant form results in increased expression of CCND1 protein] which results in increased susceptibility to palbociclib more ... CTD PMID:24098593 palbociclib multiple interactions ISO RGD:737039 6480464 [CDKN2A protein co-treated with CDKN2C protein] affects the susceptibility to palbociclib CTD PMID:20534551 palbociclib increases response to substance ISO RGD:737039 6480464 CDKN2A gene mutant form results in increased susceptibility to palbociclib CTD PMID:21278246 paracetamol decreases expression ISO RGD:737039 6480464 Acetaminophen results in decreased expression of CDKN2A mRNA CTD PMID:26690555 paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of CDKN2A mRNA CTD PMID:29859004 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CDKN2A mRNA CTD PMID:29859004 parathion increases expression ISO RGD:737039 6480464 Parathion results in increased expression of CDKN2A mRNA CTD PMID:17390078 perfluorooctanoic acid increases expression ISO RGD:737039 6480464 perfluorooctanoic acid results in increased expression of CDKN2A mRNA CTD PMID:22425687 , PMID:25868421 phenethyl caffeate increases expression EXP 6480464 caffeic acid phenethyl ester results in increased expression of CDKN2A protein CTD PMID:15885897 phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA] CTD PMID:20360939 phenobarbital multiple interactions ISO RGD:10322 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDKN2A protein CTD PMID:15082532 phenylmercury acetate multiple interactions ISO RGD:737039 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDKN2A mRNA CTD PMID:27188386 phenylmercury acetate increases expression ISO RGD:737039 6480464 Phenylmercuric Acetate results in increased expression of CDKN2A mRNA CTD PMID:26272509 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:23313794 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10322 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN2A mRNA CTD PMID:16368122 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:737039 6480464 [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA CTD PMID:18922899 pirinixic acid increases expression ISO RGD:10322 6480464 pirinixic acid results in increased expression of CDKN2A mRNA CTD PMID:16221962 pirinixic acid multiple interactions ISO RGD:737039 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CDKN2A mRNA CTD PMID:19710929 pirinixic acid multiple interactions ISO RGD:10322 6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of CDKN2A mRNA] CTD PMID:16221962 piroxicam multiple interactions EXP 6480464 Piroxicam inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA], Piroxicam inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A protein] CTD PMID:12189186 potassium dichromate increases expression ISO RGD:737039 6480464 Potassium Dichromate results in increased expression of CDKN2A mRNA, Potassium Dichromate results in increased expression of CDKN2A protein CTD PMID:23718831 , PMID:23940686 prednisone increases expression ISO RGD:737039 6480464 Prednisone results in increased expression of CDKN2A protein CTD PMID:15034294 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [Doxorubicin results in increased expression of CDKN2A protein] CTD PMID:33484087 procainamide increases expression ISO RGD:737039 6480464 Procainamide results in increased expression of CDKN2A protein CTD PMID:17938735 promethazine decreases expression EXP 6480464 Promethazine results in decreased expression of CDKN2A mRNA CTD PMID:26011634 pterostilbene multiple interactions ISO RGD:10322 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]] more ... CTD PMID:34405320 pterostilbene multiple interactions ISO RGD:737039 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]] more ... CTD PMID:34405320 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Doxorubicin results in increased expression of CDKN2A protein alternative form], Quercetin inhibits the reaction [Doxorubicin results in increased expression of CDKN2A protein] CTD PMID:24902966 quercetin increases expression ISO RGD:737039 6480464 Quercetin results in increased expression of CDKN2A protein CTD PMID:28251795 quercetin decreases expression ISO RGD:737039 6480464 Quercetin results in decreased expression of CDKN2A mRNA CTD PMID:23727915 quercetin multiple interactions ISO RGD:737039 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CDKN2A mRNA CTD PMID:27514524 quercetin decreases methylation ISO RGD:737039 6480464 Quercetin results in decreased methylation of CDKN2A promoter CTD PMID:18974642 quinoline increases expression ISO RGD:737039 6480464 quinoline analog results in increased expression of CDKN2A mRNA, quinoline analog results in increased expression of CDKN2A protein CTD PMID:19417133 quinoline decreases methylation ISO RGD:737039 6480464 quinoline analog results in decreased methylation of CDKN2A promoter CTD PMID:19417133 radon atom increases methylation ISO RGD:737039 6480464 Radon results in increased methylation of CDKN2A promoter CTD PMID:16902270 radon(0) increases methylation ISO RGD:737039 6480464 Radon results in increased methylation of CDKN2A promoter CTD PMID:16902270 reserpine multiple interactions EXP 6480464 [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein], [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 resveratrol decreases expression ISO RGD:737039 6480464 resveratrol results in decreased expression of CDKN2A mRNA CTD PMID:17804521 resveratrol multiple interactions ISO RGD:737039 6480464 CBX7 protein inhibits the reaction [Resveratrol results in increased expression of CDKN2A protein], PARP1 protein affects the reaction [Resveratrol results in increased expression of CDKN2A protein] CTD PMID:25533949 , PMID:32621571 resveratrol increases expression ISO RGD:737039 6480464 Resveratrol results in increased expression of CDKN2A protein CTD PMID:25533949 , PMID:32621571 S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO RGD:10322 6480464 S-(1, 2-dichlorovinyl)cysteine results in decreased expression of CDKN2A protein CTD PMID:16495211 salubrinal multiple interactions EXP 6480464 salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA] CTD PMID:23690541 SB 203580 multiple interactions ISO RGD:737039 6480464 SB 203580 inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN2A protein] CTD PMID:31734849 SB 431542 multiple interactions ISO RGD:737039 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 serpentine asbestos decreases expression EXP 6480464 Asbestos more ... CTD PMID:32755622 silver(1+) nitrate increases expression ISO RGD:737039 6480464 Silver Nitrate results in increased expression of CDKN2A mRNA CTD PMID:22831968 simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of CDKN2A protein CTD PMID:18804536 sodium arsenate decreases expression ISO RGD:737039 6480464 sodium arsenate results in decreased expression of CDKN2A mRNA CTD PMID:11825526 sodium arsenate increases methylation ISO RGD:737039 6480464 sodium arsenate results in increased methylation of CDKN2A gene CTD PMID:11825526 sodium arsenite multiple interactions ISO RGD:10322 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN2A mRNA more ... CTD PMID:16368122 more ... sodium arsenite multiple interactions ISO RGD:737039 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of CDKN2A mRNA CTD PMID:12634122 sodium arsenite decreases expression ISO RGD:737039 6480464 sodium arsenite results in decreased expression of CDKN2A mRNA more ... CTD PMID:11825526 more ... sodium arsenite increases expression ISO RGD:737039 6480464 sodium arsenite results in increased expression of CDKN2A mRNA CTD PMID:12016162 , PMID:12634122 sodium arsenite increases methylation ISO RGD:737039 6480464 sodium arsenite results in increased methylation of CDKN2A gene CTD PMID:11825526 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CDKN2A mRNA, sodium arsenite results in decreased expression of CDKN2A protein CTD PMID:16876216 sodium arsenite increases expression ISO RGD:10322 6480464 sodium arsenite results in increased expression of CDKN2A mRNA more ... CTD PMID:23890198 , PMID:25787150 sodium arsenite decreases expression ISO RGD:10322 6480464 sodium arsenite results in decreased expression of CDKN2A mRNA CTD PMID:22733434 sodium arsenite affects expression ISO RGD:10322 6480464 sodium arsenite affects the expression of CDKN2A mRNA CTD PMID:16507464 sodium dichromate decreases expression ISO RGD:10322 6480464 sodium bichromate results in decreased expression of CDKN2A mRNA CTD PMID:22613061 sodium dichromate multiple interactions ISO RGD:10322 6480464 Benzo(a)pyrene affects the reaction [sodium bichromate results in decreased expression of CDKN2A mRNA] CTD PMID:22613061 sodium fluoride decreases expression ISO RGD:10322 6480464 Sodium Fluoride results in decreased expression of CDKN2A mRNA CTD PMID:27862939 sodium fluoride increases methylation ISO RGD:737039 6480464 Sodium Fluoride results in increased methylation of CDKN2A promoter CTD PMID:30259626 sodium fluoride decreases expression ISO RGD:737039 6480464 Sodium Fluoride results in decreased expression of CDKN2A mRNA, Sodium Fluoride results in decreased expression of CDKN2A protein CTD PMID:30259626 sodium fluoride multiple interactions ISO RGD:737039 6480464 Decitabine inhibits the reaction [Sodium Fluoride results in decreased expression of CDKN2A mRNA] more ... CTD PMID:30259626 spironolactone multiple interactions EXP 6480464 Spironolactone inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein], Spironolactone inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 stavudine affects expression ISO RGD:10322 6480464 Stavudine affects the expression of CDKN2A protein CTD PMID:18389896 streptozocin multiple interactions ISO RGD:10322 6480464 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA] more ... CTD PMID:29059224 , PMID:29673160 streptozocin increases expression ISO RGD:10322 6480464 Streptozocin results in increased expression of CDKN2A mRNA, Streptozocin results in increased expression of CDKN2A protein CTD PMID:29059224 , PMID:29673160 sulforaphane multiple interactions ISO RGD:10322 6480464 sulforaphane inhibits the reaction [[NFE2L2 protein affects the susceptibility to 1 more ... CTD PMID:26388957 sulforaphane decreases expression ISO RGD:10322 6480464 sulforaphane results in decreased expression of CDKN2A mRNA CTD PMID:30529165 sulfur dioxide multiple interactions EXP 6480464 [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA more ... CTD PMID:19408242 , PMID:20064080 sulfur dioxide decreases expression EXP 6480464 Sulfur Dioxide results in decreased expression of CDKN2A mRNA, Sulfur Dioxide results in decreased expression of CDKN2A protein CTD PMID:19408242 more ... sulfur dioxide increases expression EXP 6480464 Sulfur Dioxide results in increased expression of CDKN2A protein CTD PMID:19408242 sulindac multiple interactions EXP 6480464 Sulindac inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA] CTD PMID:12189186 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of CDKN2A mRNA, T-2 Toxin results in increased expression of CDKN2A protein CTD PMID:29567467 terephthalic acid decreases expression EXP 6480464 terephthalic acid results in decreased expression of CDKN2A protein CTD PMID:16896691 tetrachloromethane multiple interactions ISO RGD:10322 6480464 [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA CTD PMID:23288052 tetrachloromethane increases expression ISO RGD:10322 6480464 Carbon Tetrachloride results in increased expression of CDKN2A mRNA CTD PMID:23288052 thioacetamide affects localization EXP 6480464 Thioacetamide affects the localization of CDKN2A protein CTD PMID:22659510 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of CDKN2A mRNA CTD PMID:26011634 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CDKN2A protein CTD PMID:22659510 , PMID:23411599 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of CDKN2A mRNA CTD PMID:22659510 thioridazine increases expression ISO RGD:737039 6480464 Thioridazine results in increased expression of CDKN2A protein CTD PMID:21035837 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of CDKN2A mRNA CTD PMID:30012374 trichostatin A multiple interactions ISO RGD:737039 6480464 [[decitabine co-treated with trichostatin A] affects the methylation of CDKN2A promoter] which affects the expression of CDKN2A mRNA more ... CTD PMID:17019711 more ... trichostatin A increases expression ISO RGD:737039 6480464 trichostatin A results in increased expression of CDKN2A mRNA, trichostatin A results in increased expression of CDKN2A protein CTD PMID:23770000 trichostatin A decreases expression ISO RGD:737039 6480464 trichostatin A results in decreased expression of CDKN2A mRNA CTD PMID:19606018 triclosan increases methylation ISO RGD:737039 6480464 Triclosan results in increased methylation of CDKN2A gene CTD PMID:26970259 triclosan decreases expression ISO RGD:737039 6480464 Triclosan results in decreased expression of CDKN2A mRNA alternative form CTD PMID:26970259 urethane decreases expression ISO RGD:10322 6480464 Urethane results in decreased expression of CDKN2A mRNA, Urethane results in decreased expression of CDKN2A protein CTD PMID:12117781 , PMID:25168426 urethane increases response to substance ISO RGD:10322 6480464 CDKN2A gene polymorphism results in increased susceptibility to Urethane CTD PMID:11544531 valproic acid increases methylation ISO RGD:737039 6480464 Valproic Acid results in increased methylation of CDKN2A gene CTD PMID:29154799 valproic acid increases expression ISO RGD:737039 6480464 Valproic Acid results in increased expression of CDKN2A mRNA CTD PMID:19101580 more ... valproic acid affects expression ISO RGD:737039 6480464 Valproic Acid affects the expression of CDKN2A mRNA CTD PMID:25979313 vincristine increases response to substance ISO RGD:737039 6480464 CDKN2A protein results in increased susceptibility to Vincristine CTD PMID:16786135 vinorelbine decreases expression ISO RGD:737039 6480464 vinorelbine results in decreased expression of CDKN2A protein CTD PMID:17904787 wogonin increases expression ISO RGD:737039 6480464 wogonin results in increased expression of CDKN2A mRNA, wogonin results in increased expression of CDKN2A protein CTD PMID:32671444 zearalenone decreases expression ISO RGD:737039 6480464 Zearalenone results in decreased expression of CDKN2A mRNA CTD PMID:28965971 zidovudine affects expression ISO RGD:10322 6480464 Zidovudine affects the expression of CDKN2A protein CTD PMID:18389896 zidovudine increases expression ISO RGD:737039 6480464 Zidovudine results in increased expression of CDKN2A mRNA, Zidovudine results in increased expression of CDKN2A protein CTD PMID:16797627 zinc pyrithione affects expression ISO RGD:737039 6480464 pyrithione zinc affects the expression of CDKN2A protein CTD PMID:21557991
