Palld (palladin, cytoskeletal associated protein) - Rat Genome Database

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Gene: Palld (palladin, cytoskeletal associated protein) Rattus norvegicus
Analyze
Symbol: Palld
Name: palladin, cytoskeletal associated protein
RGD ID: 2322545
Description: Enables cytoskeletal protein binding activity. Involved in several processes, including plasma membrane bounded cell projection organization; positive regulation of podosome assembly; and trophoblast giant cell differentiation. Located in several cellular components, including Z disc; actin cytoskeleton; and axonal growth cone. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human PALLD (palladin, cytoskeletal associated protein); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07025295.1; LOC100360205; LOC103693936; LOC290704; palladin; palladin-like; palladin-like 1; Palldl1; similar to palladin
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,238,943 - 33,632,236 (+)NCBIGRCr8
mRatBN7.21628,228,006 - 28,621,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1627,981,354 - 28,621,337 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01631,865,712 - 31,948,168 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1631,734,944 - 31,946,242 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01631,401,114 - 31,786,201 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41631,854,459 - 31,933,792NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1628,535,132 - 28,616,857 (+)NCBICelera
Cytogenetic Map16p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-butoxyethanol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
ketoconazole  (ISO)
L-glutamic acid  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nickel sulfate  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tebuconazole  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
tetrahydropalmatine  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin cytoskeleton  (ISO)
actin filament  (IEA,ISO)
axon  (IDA)
axonal growth cone  (IDA)
cytoskeleton  (IDA,ISO)
cytosol  (IEA,ISO)
excitatory synapse  (IDA)
filopodium  (IDA)
focal adhesion  (IEA,ISO)
growth cone  (IDA)
lamellipodium  (IEA,ISO)
mitochondrion  (IEA,ISO)
neuronal cell body  (IDA)
nucleus  (IEA,ISO)
plasma membrane  (IEA,ISO)
podosome  (IDA)
ruffle  (IDA)
stress fiber  (IDA,IEA,IMP,ISO)
Z disc  (IDA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A role for the cytoskeleton-associated protein palladin in neurite outgrowth. Boukhelifa M, etal., Mol Biol Cell. 2001 Sep;12(9):2721-9. doi: 10.1091/mbc.12.9.2721.
2. A critical role for palladin in astrocyte morphology and response to injury. Boukhelifa M, etal., Mol Cell Neurosci. 2003 Aug;23(4):661-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells. Goicoechea S, etal., J Cell Sci. 2006 Aug 15;119(Pt 16):3316-24. Epub 2006 Jul 25.
5. Isoform-specific upregulation of palladin in human and murine pancreas tumors. Goicoechea SM, etal., PLoS One. 2010 Apr 26;5(4):e10347.
6. Hypoxia inhibits differentiation of lineage-specific Rcho-1 trophoblast giant cells. Gultice AD, etal., Biol Reprod. 2006 Jun;74(6):1041-50. Epub 2006 Feb 15.
7. Palladin is expressed preferentially in excitatory terminals in the rat central nervous system. Hwang SJ, etal., J Comp Neurol. 2001 Jul 23;436(2):211-24.
8. CLP36 and RIL recruit a-actinin-1 to stress fibers and differentially regulate stress fiber dynamics in F2408 fibroblasts. Miyazaki K, etal., Exp Cell Res. 2012 Aug 15;318(14):1716-25. doi: 10.1016/j.yexcr.2012.05.006. Epub 2012 May 30.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. Pogue-Geile KL, etal., PLoS Med. 2006 Dec;3(12):e516.
11. Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes. Qian X, etal., Endocrinology. 2013 May;154(5):1907-20. doi: 10.1210/en.2012-2269. Epub 2013 Apr 1.
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation. Ronty MJ, etal., J Invest Dermatol. 2006 Nov;126(11):2387-96. Epub 2006 Jun 22.
16. Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton. Rönty M, etal., Exp Cell Res. 2005 Oct 15;310(1):88-98. doi: 10.1016/j.yexcr.2005.06.026.
17. Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells. Salaria SN, etal., Cancer Biol Ther. 2007 Mar;6(3):324-8. Epub 2007 Mar 24.
Additional References at PubMed
PMID:10931874   PMID:11598191   PMID:17322171   PMID:17537434   PMID:21423176   PMID:24012369   PMID:33450132   PMID:37712274  


Genomics

Comparative Map Data
Palld
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,238,943 - 33,632,236 (+)NCBIGRCr8
mRatBN7.21628,228,006 - 28,621,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1627,981,354 - 28,621,337 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01631,865,712 - 31,948,168 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1631,734,944 - 31,946,242 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01631,401,114 - 31,786,201 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41631,854,459 - 31,933,792NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1628,535,132 - 28,616,857 (+)NCBICelera
Cytogenetic Map16p12NCBI
PALLD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384168,497,052 - 168,928,441 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4168,497,052 - 168,928,457 (+)EnsemblGRCh38hg38GRCh38
GRCh374169,418,203 - 169,849,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364169,654,792 - 170,086,183 (+)NCBINCBI36Build 36hg18NCBI36
Celera4166,748,020 - 167,180,983 (+)NCBICelera
Cytogenetic Map4q32.3NCBI
HuRef4165,170,970 - 165,603,126 (+)NCBIHuRef
CHM1_14169,394,774 - 169,826,047 (+)NCBICHM1_1
T2T-CHM13v2.04171,856,045 - 172,287,862 (+)NCBIT2T-CHM13v2.0
Palld
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39861,964,465 - 62,355,741 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl861,964,467 - 62,355,724 (-)EnsemblGRCm39 Ensembl
GRCm38861,511,431 - 61,902,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl861,511,433 - 61,902,690 (-)EnsemblGRCm38mm10GRCm38
MGSCv37863,993,818 - 64,381,487 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36864,403,398 - 64,794,832 (-)NCBIMGSCv36mm8
Celera864,078,203 - 64,475,199 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map831.23NCBI
PALLD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23166,273,693 - 166,697,100 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14166,787,075 - 167,052,445 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04160,718,475 - 161,140,436 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14173,120,958 - 173,216,409 (+)NCBIpanpan1.1PanPan1.1panPan2
PALLD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12519,147,310 - 19,568,712 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2519,146,898 - 19,553,679 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2519,178,454 - 19,599,760 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02519,285,396 - 19,694,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2519,285,412 - 19,694,079 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12519,146,258 - 19,574,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02519,153,183 - 19,562,304 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02519,215,651 - 19,637,403 (+)NCBIUU_Cfam_GSD_1.0
Palld
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494320,372,101 - 20,739,513 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936516802,484 - 1,151,801 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936516786,358 - 1,151,910 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PALLD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,678,452 - 21,020,125 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11420,678,456 - 21,020,125 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,965,285 - 22,200,581 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PALLD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17114,758,017 - 115,173,240 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603794,642,207 - 95,083,209 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Palld
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624769150,738 - 559,045 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624769150,800 - 560,163 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Palld
2161 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:391
Count of miRNA genes:192
Interacting mature miRNAs:211
Transcripts:ENSRNOT00000013636, ENSRNOT00000059673, ENSRNOT00000064850, ENSRNOT00000066265
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat

Markers in Region
D16Rat18  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81633,565,275 - 33,565,431 (+)Marker Load Pipeline
mRatBN7.21628,554,370 - 28,554,528 (+)MAPPERmRatBN7.2
Rnor_6.01631,881,203 - 31,881,358NCBIRnor6.0
Rnor_5.01631,720,124 - 31,720,279UniSTSRnor5.0
RGSC_v3.41631,868,072 - 31,868,228RGDRGSC3.4
RGSC_v3.41631,868,073 - 31,868,228UniSTSRGSC3.4
RGSC_v3.11631,867,979 - 31,868,331RGD
Celera1628,549,531 - 28,549,686UniSTS
RH 2.0 Map16362.8RGD
FHH x ACI Map1620.0199RGD
D16Mco10  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81633,583,698 - 33,584,066 (+)Marker Load Pipeline
mRatBN7.21628,572,799 - 28,573,169 (+)MAPPERmRatBN7.2
Rnor_6.01631,899,635 - 31,900,002NCBIRnor6.0
Rnor_5.01631,738,901 - 31,739,268UniSTSRnor5.0
RGSC_v3.41631,886,283 - 31,886,651RGDRGSC3.4
RGSC_v3.41631,886,284 - 31,886,651UniSTSRGSC3.4
RGSC_v3.11631,886,358 - 31,886,726RGD
Celera1628,568,309 - 28,568,676UniSTS
Cytogenetic Map16 RGD
RH143884  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21628,620,160 - 28,620,310 (+)MAPPERmRatBN7.2
Rnor_6.01631,946,985 - 31,947,134NCBIRnor6.0
Rnor_5.01631,785,018 - 31,785,167UniSTSRnor5.0
RGSC_v3.41631,933,337 - 31,933,486UniSTSRGSC3.4
Celera1628,615,674 - 28,615,823UniSTS
AU046415  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21628,493,639 - 28,493,872 (+)MAPPERmRatBN7.2
Rnor_6.01631,817,845 - 31,818,077NCBIRnor6.0
Rnor_5.01631,659,302 - 31,659,534UniSTSRnor5.0
RGSC_v3.41631,808,078 - 31,808,310UniSTSRGSC3.4
Celera1628,489,214 - 28,489,446UniSTS
GDB:187424  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21628,291,913 - 28,293,343 (+)MAPPERmRatBN7.2
Rnor_6.01631,606,413 - 31,607,842NCBIRnor6.0
Rnor_5.01631,455,054 - 31,456,483UniSTSRnor5.0
Celera1628,287,265 - 28,288,694UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001433250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000059673   ⟹   ENSRNOP00000056425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,418,961 - 28,621,337 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000064850   ⟹   ENSRNOP00000084755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1627,981,354 - 28,022,515 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000067450   ⟹   ENSRNOP00000086932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1627,999,122 - 28,022,526 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095888   ⟹   ENSRNOP00000080820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,228,014 - 28,621,337 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111769   ⟹   ENSRNOP00000091553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1627,999,196 - 28,620,047 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113224   ⟹   ENSRNOP00000090355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1627,999,196 - 28,621,337 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113275   ⟹   ENSRNOP00000093125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1627,999,122 - 28,006,116 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116705   ⟹   ENSRNOP00000088354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1628,540,427 - 28,621,070 (+)Ensembl
RefSeq Acc Id: XM_008771231   ⟹   XP_008769453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,551,169 - 33,632,236 (+)NCBI
mRatBN7.21628,539,993 - 28,621,349 (+)NCBI
Rnor_6.01631,865,714 - 31,948,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771232   ⟹   XP_008769454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,551,183 - 33,632,236 (+)NCBI
mRatBN7.21628,539,997 - 28,621,349 (+)NCBI
Rnor_6.01631,865,715 - 31,948,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094914   ⟹   XP_038950842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,238,944 - 33,632,236 (+)NCBI
mRatBN7.21628,228,007 - 28,621,349 (+)NCBI
RefSeq Acc Id: XM_039094915   ⟹   XP_038950843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,238,944 - 33,632,236 (+)NCBI
mRatBN7.21628,228,008 - 28,621,349 (+)NCBI
RefSeq Acc Id: XM_039094916   ⟹   XP_038950844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,238,943 - 33,630,272 (+)NCBI
mRatBN7.21628,228,006 - 28,619,384 (+)NCBI
RefSeq Acc Id: XM_039094917   ⟹   XP_038950845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,380,774 - 33,632,236 (+)NCBI
mRatBN7.21628,369,849 - 28,621,349 (+)NCBI
RefSeq Acc Id: XP_008769453   ⟸   XM_008771231
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008769454   ⟸   XM_008771232
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_038950844   ⟸   XM_039094916
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950842   ⟸   XM_039094914
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950843   ⟸   XM_039094915
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ADH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950845   ⟸   XM_039094917
- Peptide Label: isoform X4
- UniProtKB: F1M265 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088354   ⟸   ENSRNOT00000116705
Ensembl Acc Id: ENSRNOP00000091553   ⟸   ENSRNOT00000111769
Ensembl Acc Id: ENSRNOP00000080820   ⟸   ENSRNOT00000095888
Ensembl Acc Id: ENSRNOP00000084755   ⟸   ENSRNOT00000064850
Ensembl Acc Id: ENSRNOP00000093125   ⟸   ENSRNOT00000113275
Ensembl Acc Id: ENSRNOP00000090355   ⟸   ENSRNOT00000113224
Ensembl Acc Id: ENSRNOP00000086932   ⟸   ENSRNOT00000067450
Ensembl Acc Id: ENSRNOP00000056425   ⟸   ENSRNOT00000059673
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C5E3-F1-model_v2 AlphaFold P0C5E3 1-603 view protein structure
AF-F1M265-F1-model_v2 AlphaFold F1M265 1-1002 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2322545 AgrOrtholog
BioCyc Gene G2FUF-11591 BioCyc
Ensembl Genes ENSRNOG00000010107 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000059673.6 UniProtKB/TrEMBL
  ENSRNOT00000095888.1 UniProtKB/TrEMBL
  ENSRNOT00000111769.1 UniProtKB/TrEMBL
  ENSRNOT00000113224.1 UniProtKB/TrEMBL
  ENSRNOT00000116705.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cell_Adh-Cytoskel_Orgn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Palladin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 100360205 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOTILIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ROUNDABOUT HOMOLOG 1 UniProtKB/TrEMBL
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Palld PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010107 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQM3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9U3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADH4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADX4_RAT UniProtKB/TrEMBL
  F1M265 ENTREZGENE, UniProtKB/TrEMBL
  PALLD_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Palld  palladin, cytoskeletal associated protein  AABR07025295.1    Data merged from RGD:15003360 737654 PROVISIONAL
2021-09-02 AABR07025295.1    Palldl1  palladin-like 1  Symbol and/or name change 19259462 PROVISIONAL
2021-08-09 Palldl1  palladin-like 1  AABR07025295.1    Symbol and/or name change 19259462 PROVISIONAL
2021-03-09 Palld  palladin, cytoskeletal associated protein  LOC103693936  palladin-like  Data merged from RGD:9212281 737654 PROVISIONAL
2019-11-08 AABR07025295.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2014-08-25 LOC103693936  palladin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-08-01 LOC100360205  palladin  LOC290704  similar to palladin  Data merged from RGD:1588598 737654 APPROVED
2013-08-01 Palld  palladin, cytoskeletal associated protein  LOC100360205  palladin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100360205  palladin      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC290704  similar to palladin      Symbol and Name status set to provisional 70820 PROVISIONAL