Sh2d3a (SH2 domain containing 3A) - Rat Genome Database

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Gene: Sh2d3a (SH2 domain containing 3A) Rattus norvegicus
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Symbol: Sh2d3a
Name: SH2 domain containing 3A
RGD ID: 2322080
Description: Orthologous to human SH2D3A (SH2 domain containing 3A); INTERACTS WITH aflatoxin B1 (ortholog); arsenous acid (ortholog); benzo[a]pyrene (ortholog).
Type: pseudo
RefSeq Status: INFERRED
Previously known as: hypothetical LOC100360476; LOC100360476; SH2 domain-containing protein 3A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr892,235,359 - 2,239,578 (-)NCBIGRCr8
mRatBN7.292,148,803 - 2,158,150 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.099,678,929 - 9,688,387 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.098,691,152 - 8,696,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,360,823 - 6,373,423 (+)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
Sh2d3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr892,235,359 - 2,239,578 (-)NCBIGRCr8
mRatBN7.292,148,803 - 2,158,150 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.099,678,929 - 9,688,387 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.098,691,152 - 8,696,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,360,823 - 6,373,423 (+)NCBICelera
Cytogenetic Map9q11NCBI
SH2D3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,752,160 - 6,767,435 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl196,752,160 - 6,767,463 (-)EnsemblGRCh38hg38GRCh38
GRCh37196,752,171 - 6,767,446 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,703,171 - 6,718,480 (-)NCBINCBI36Build 36hg18NCBI36
Build 34196,703,174 - 6,718,480NCBI
Celera196,694,421 - 6,709,773 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef196,514,650 - 6,530,002 (-)NCBIHuRef
CHM1_1196,752,022 - 6,767,374 (-)NCBICHM1_1
T2T-CHM13v2.0196,741,555 - 6,756,831 (-)NCBIT2T-CHM13v2.0
Gm46575
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391757,570,959 - 57,574,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1757,571,262 - 57,574,922 (-)EnsemblGRCm39 Ensembl
GRCm381757,263,959 - 57,267,945 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1757,264,262 - 57,267,922 (-)EnsemblGRCm38mm10GRCm38
Cytogenetic Map17DNCBI
Sh2d3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554952,757,798 - 2,769,730 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554952,758,214 - 2,769,867 (+)NCBIChiLan1.0ChiLan1.0
SH2D3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22011,165,499 - 11,181,119 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11910,391,571 - 10,407,191 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0195,784,482 - 5,800,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1196,706,040 - 6,720,757 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl196,706,040 - 6,720,757 (-)Ensemblpanpan1.1panPan2
SH2D3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12053,533,805 - 53,543,675 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2053,533,721 - 53,546,675 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2053,282,319 - 53,294,339 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02054,188,704 - 54,200,328 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2054,188,688 - 54,198,571 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12053,255,676 - 53,267,697 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,703,668 - 53,715,689 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,933,091 - 53,945,122 (+)NCBIUU_Cfam_GSD_1.0
Sh2d3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,782,063 - 213,789,826 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365884,044,938 - 4,052,123 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH2D3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl272,394,374 - 72,406,235 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1272,394,292 - 72,406,242 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2272,673,643 - 72,685,559 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SH2D3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.166,321,187 - 6,334,922 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660811,658,154 - 1,674,319 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh2d3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248283,824,471 - 3,836,073 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

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Variants in Sh2d3a
64 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat

Markers in Region
AU048842  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.292,151,732 - 2,151,868 (-)MAPPERmRatBN7.2
Rnor_6.099,685,139 - 9,685,276NCBIRnor6.0
Rnor_5.098,692,467 - 8,692,604UniSTSRnor5.0
Celera96,370,175 - 6,370,312UniSTS


Expression


Sequence


RefSeq Acc Id: XM_039084349   ⟹   XP_038940277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.292,148,803 - 2,158,150 (-)NCBI

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2322080 AgrOrtholog
BioCyc Gene G2FUF-28480 BioCyc
NCBI Gene 100360476 ENTREZGENE
PhenoGen Sh2d3a PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-05 Sh2d3a  SH2 domain containing 3A  LOC100360476  hypothetical LOC100360476  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100360476  hypothetical LOC100360476      Symbol and Name status set to provisional 70820 PROVISIONAL