Cbr1l3 (carbonyl reductase 1 like 3) - Rat Genome Database

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Gene: Cbr1l3 (carbonyl reductase 1 like 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cbr1l3
Name: carbonyl reductase 1 like 3
RGD ID: 2321756
Description: Predicted to enable carbonyl reductase (NADPH) activity. Predicted to be located in cytoplasm.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: carbonyl reductase 2-like; carbonyl reductase [NADPH] 1-like; LOC100360601
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81146,455,392 - 46,461,863 (+)NCBIGRCr8
mRatBN7.21132,985,136 - 32,992,000 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1132,985,707 - 32,992,000 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01133,886,956 - 33,893,434 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1133,887,142 - 33,893,433 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01137,478,384 - 37,484,677 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41133,889,579 - 33,895,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1135,451,995 - 35,458,473 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Cbr1l3
28 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:27
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000075105
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 112 88 88 58 25 58 6 216 96 92 45 59 30

Sequence


Ensembl Acc Id: ENSRNOT00000041838   ⟹   ENSRNOP00000051107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1132,985,707 - 32,992,000 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1133,887,142 - 33,893,433 (+)Ensembl
RefSeq Acc Id: XM_063270851   ⟹   XP_063126921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81146,455,392 - 46,461,863 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063126921 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051107.5
Ensembl Acc Id: ENSRNOP00000051107   ⟸   ENSRNOT00000041838
RefSeq Acc Id: XP_063126921   ⟸   XM_063270851

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-21789 BioCyc
Ensembl Genes ENSRNOG00000049380 Ensembl
  ENSRNOG00000049693 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041838.6 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro CBR1-like UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene 100360601 ENTREZGENE
PANTHER CARBONYL REDUCTASE 1-RELATED UniProtKB/TrEMBL
  CARBONYL REDUCTASE [NADPH] 1 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PhenoGen Cbr1l3 PhenoGen
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049380 RatGTEx
  ENSRNOG00000049693 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0G2JSW9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Cbr1l3  carbonyl reductase 1 like 3  LOC100360601  carbonyl reductase 2-like  Symbol and Name Changed 1299863 APPROVED
2010-05-06 LOC100360601  carbonyl reductase 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL