Prmt1l1 (protein arginine methyltransferase 1 like 1) - Rat Genome Database

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Gene: Prmt1l1 (protein arginine methyltransferase 1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Prmt1l1 (Ensembl: LOC100361025)
Name: protein arginine methyltransferase 1 like 1 (Ensembl:protein arginine methyltransferase 1-like)
RGD ID: 2320935
Description: Predicted to enable histone methyltransferase activity and protein-arginine N-methyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Predicted to be located in cytosol and nucleoplasm. Orthologous to human PRMT1 (protein arginine methyltransferase 1).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100361025; protein arginine methyltransferase 1-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81491,764,602 - 91,765,863 (-)NCBIGRCr8
mRatBN7.21487,551,165 - 87,552,305 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1487,551,207 - 87,552,294 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01493,040,967 - 93,042,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1493,040,982 - 93,042,182 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01492,831,775 - 92,833,028 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41493,881,125 - 93,882,381 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1486,680,943 - 86,682,195 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Prmt1l1
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:80
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000005432
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat

Markers in Region
BI285876  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,458,857 - 95,459,077 (+)MAPPERmRatBN7.2
mRatBN7.21487,551,063 - 87,551,283 (+)MAPPERmRatBN7.2
Rnor_6.01100,971,137 - 100,971,356NCBIRnor6.0
Rnor_6.01493,040,983 - 93,041,202NCBIRnor6.0
Rnor_5.01492,831,791 - 92,832,010UniSTSRnor5.0
Rnor_5.01102,035,577 - 102,035,796UniSTSRnor5.0
RGSC_v3.4195,449,062 - 95,449,281UniSTSRGSC3.4
RGSC_v3.41493,881,141 - 93,881,360UniSTSRGSC3.4
Celera1486,680,959 - 86,681,178UniSTS
Celera189,720,387 - 89,720,606UniSTS
RH 3.4 Map14654.09UniSTS
Cytogenetic Map1q22UniSTS
Hrmt1l2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21767,626,147 - 67,626,358 (+)MAPPERmRatBN7.2
mRatBN7.21487,552,031 - 87,552,243 (+)MAPPERmRatBN7.2
Rnor_6.01493,041,951 - 93,042,162NCBIRnor6.0
Rnor_6.01771,397,715 - 71,397,925NCBIRnor6.0
Rnor_5.01773,092,124 - 73,092,334UniSTSRnor5.0
Rnor_5.01492,832,759 - 92,832,970UniSTSRnor5.0
RGSC_v3.41493,882,109 - 93,882,320UniSTSRGSC3.4
RGSC_v3.41778,879,926 - 78,880,136UniSTSRGSC3.4
Celera1767,123,381 - 67,123,591UniSTS
Celera1486,681,927 - 86,682,138UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000005432   ⟹   ENSRNOP00000075012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1487,551,207 - 87,552,294 (-)Ensembl
Rnor_6.0 Ensembl1493,040,982 - 93,042,182 (-)Ensembl
RefSeq Acc Id: XM_039092860   ⟹   XP_038948788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81491,764,602 - 91,765,863 (-)NCBI
mRatBN7.21487,551,165 - 87,552,305 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038948788 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063624.3
  ENSRNOP00000075012.2
Ensembl Acc Id: ENSRNOP00000075012   ⟸   ENSRNOT00000005432
RefSeq Acc Id: XP_038948788   ⟸   XM_039092860
- UniProtKB: A0A8L2QUM0 (UniProtKB/TrEMBL)
Protein Domains
Methyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9I8-F1-model_v2 AlphaFold A0A0G2K9I8 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699497
Promoter ID:EPDNEW_R10020
Type:multiple initiation site
Name:LOC100361025_1
Description:protein arginine methyltransferase 1-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01493,042,195 - 93,042,255EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2320935 AgrOrtholog
BioCyc Gene G2FUF-14967 BioCyc
Ensembl Genes ENSRNOG00000004090 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000026109 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005432.6 UniProtKB/TrEMBL
  ENSRNOT00000064272.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
  Hnrnp arginine n-methyltransferase1 UniProtKB/TrEMBL
InterPro Arg_MeTrfase UniProtKB/TrEMBL
  Methyltransf_25 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene 100361025 ENTREZGENE
PANTHER PROTEIN ARGININE N-METHYLTRANSFERASE 1 UniProtKB/TrEMBL
  PTHR11006 UniProtKB/TrEMBL
Pfam Methyltransf_25 UniProtKB/TrEMBL
PhenoGen Prmt1l1 PhenoGen
PROSITE SAM_MT_PRMT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004090 RatGTEx
  ENSRNOG00000026109 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0G2K9I8_RAT UniProtKB/TrEMBL
  A0A8L2QUM0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Prmt1l1  protein arginine methyltransferase 1 like 1  LOC100361025  protein arginine methyltransferase 1-like  Symbol and Name Changed 1299863 APPROVED
2010-05-05 LOC100361025  protein arginine methyltransferase 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL