Zfp869 (zinc finger protein 869) - Rat Genome Database

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Gene: Zfp869 (zinc finger protein 869) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Zfp869
Name: zinc finger protein 869
RGD ID: 2320746
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100361114; rCG38640-like; zinc finger protein 14-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,723,788 - 19,735,115 (+)NCBIGRCr8
mRatBN7.21619,689,881 - 19,701,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,690,019 - 19,700,382 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01621,438,865 - 21,450,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,444,638 - 21,448,847 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01621,313,533 - 21,364,023 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41620,181,460 - 20,186,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1619,832,732 - 19,895,218 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Zfp869
74 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000015611
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat

Markers in Region
RH131200  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,701,019 - 19,701,199 (+)MAPPERmRatBN7.2
Rnor_6.01621,449,853 - 21,450,032NCBIRnor6.0
Rnor_5.01621,363,842 - 21,364,021UniSTSRnor5.0
RGSC_v3.41620,186,675 - 20,186,854UniSTSRGSC3.4
Celera1619,895,037 - 19,895,216UniSTS
RH 3.4 Map16217.83UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 38 52 36 19 36 6 7 74 35 40 11 6
Low 5 5 5 5 2 4 1 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001408730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide FQ211569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000015611   ⟹   ENSRNOP00000015611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1619,690,019 - 19,700,382 (+)Ensembl
Rnor_6.0 Ensembl1621,444,638 - 21,448,847 (+)Ensembl
RefSeq Acc Id: NM_001408730   ⟹   NP_001395659
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,723,943 - 19,735,115 (+)NCBI
mRatBN7.21619,690,026 - 19,701,201 (+)NCBI
RefSeq Acc Id: NM_001408731   ⟹   NP_001395660
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,126 - 19,735,115 (+)NCBI
mRatBN7.21619,690,209 - 19,701,201 (+)NCBI
RefSeq Acc Id: NM_001408732   ⟹   NP_001395661
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,126 - 19,735,115 (+)NCBI
mRatBN7.21619,690,209 - 19,701,201 (+)NCBI
RefSeq Acc Id: XM_017600335   ⟹   XP_017455824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,083 - 19,735,002 (+)NCBI
mRatBN7.21619,690,166 - 19,701,201 (+)NCBI
Rnor_6.01621,439,003 - 21,450,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600336   ⟹   XP_017455825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,083 - 19,735,002 (+)NCBI
mRatBN7.21619,690,166 - 19,701,201 (+)NCBI
Rnor_6.01621,439,003 - 21,450,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600338   ⟹   XP_017455827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,723,931 - 19,735,002 (+)NCBI
mRatBN7.21619,690,026 - 19,701,201 (+)NCBI
Rnor_6.01621,438,865 - 21,450,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600339   ⟹   XP_017455828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,772 - 19,735,002 (+)NCBI
mRatBN7.21619,691,833 - 19,701,201 (+)NCBI
Rnor_6.01621,440,667 - 21,450,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600340   ⟹   XP_017455829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,083 - 19,735,002 (+)NCBI
mRatBN7.21619,690,166 - 19,701,201 (+)NCBI
Rnor_6.01621,439,003 - 21,450,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095262   ⟹   XP_038951190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,083 - 19,735,002 (+)NCBI
mRatBN7.21619,690,166 - 19,701,201 (+)NCBI
RefSeq Acc Id: XM_039095263   ⟹   XP_038951191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,723,940 - 19,735,002 (+)NCBI
mRatBN7.21619,690,026 - 19,701,201 (+)NCBI
RefSeq Acc Id: XM_039095264   ⟹   XP_038951192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,723,955 - 19,735,002 (+)NCBI
mRatBN7.21619,690,022 - 19,701,201 (+)NCBI
RefSeq Acc Id: XM_039095265   ⟹   XP_038951193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,723,788 - 19,735,002 (+)NCBI
mRatBN7.21619,689,881 - 19,701,201 (+)NCBI
RefSeq Acc Id: XM_063274963   ⟹   XP_063131033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,724,083 - 19,735,002 (+)NCBI
RefSeq Acc Id: XP_017455827   ⟸   XM_017600338
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455824   ⟸   XM_017600335
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455825   ⟸   XM_017600336
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455829   ⟸   XM_017600340
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455828   ⟸   XM_017600339
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000015611   ⟸   ENSRNOT00000015611
RefSeq Acc Id: XP_038951193   ⟸   XM_039095265
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951192   ⟸   XM_039095264
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951191   ⟸   XM_039095263
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951190   ⟸   XM_039095262
- Peptide Label: isoform X1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001395659   ⟸   NM_001408730
- Peptide Label: isoform 1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001395660   ⟸   NM_001408731
- Peptide Label: isoform 1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001395661   ⟸   NM_001408732
- Peptide Label: isoform 1
- UniProtKB: D3ZKK4 (UniProtKB/TrEMBL),   A6KAC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131033   ⟸   XM_063274963
- Peptide Label: isoform X1
- UniProtKB: A6KAC2 (UniProtKB/TrEMBL),   D3ZKK4 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZKK4-F1-model_v2 AlphaFold D3ZKK4 1-530 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2320746 AgrOrtholog
BioCyc Gene G2FUF-11735 BioCyc
Ensembl Genes ENSRNOG00000033351 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015611 ENTREZGENE
  ENSRNOT00000015611.4 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:100361114 UniProtKB/TrEMBL
NCBI Gene 100361114 ENTREZGENE
PANTHER ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 853 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp869 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033351 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A6KAC2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKK4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-09 Zfp869  zinc finger protein 869  LOC100361114  rCG38640-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361114  rCG38640-like      Symbol and Name status set to provisional 70820 PROVISIONAL