Arhgap33 (Rho GTPase activating protein 33) - Rat Genome Database

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Gene: Arhgap33 (Rho GTPase activating protein 33) Rattus norvegicus
Analyze
Symbol: Arhgap33
Name: Rho GTPase activating protein 33
RGD ID: 2318374
Description: Predicted to enable GTPase activator activity and protein kinase binding activity. Involved in regulation of dendritic spine morphogenesis and response to toxic substance. Located in dendritic spine. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human ARHGAP33 (Rho GTPase activating protein 33); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100362311; LOC361540; rho GTPase-activating protein 33; Snx26; sorting nexin 26
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   WAG.OXYS-(D1Rat30-D1Rat219)/Nov  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,903,566 - 94,917,074 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl194,902,922 - 94,917,684 (-)EnsemblGRCr8
mRatBN7.2185,776,112 - 85,789,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)EnsemblmRatBN7.2
Rnor_6.0188,977,460 - 88,990,780 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,978,344 - 88,989,552 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,132,465 - 90,145,782 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,568,846 - 85,581,069 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,147,918 - 80,160,861 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. SNX26, a GTPase-activating protein for Cdc42, interacts with PSD-95 protein and is involved in activity-dependent dendritic spine formation in mature neurons. Kim Y, etal., J Biol Chem. 2013 Oct 11;288(41):29453-66. doi: 10.1074/jbc.M113.468801. Epub 2013 Sep 3.
3. Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders. Nakazawa T, etal., Nat Commun. 2016 Feb 3;7:10594. doi: 10.1038/ncomms10594.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. NOMA-GAP/ARHGAP33 regulates synapse development and autistic-like behavior in the mouse. Schuster S, etal., Mol Psychiatry. 2015 Sep;20(9):1120-31. doi: 10.1038/mp.2015.42. Epub 2015 Apr 14.
7. [Chronic phosphoproteomic in temporal lobe epilepsy mouse models induced by kainic acid]. Sun ZM, etal., Beijing Da Xue Xue Bao Yi Xue Ban. 2019 Apr 18;51(2):197-205.
Additional References at PubMed
PMID:12773384   PMID:20873783  


Genomics

Comparative Map Data
Arhgap33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,903,566 - 94,917,074 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl194,902,922 - 94,917,684 (-)EnsemblGRCr8
mRatBN7.2185,776,112 - 85,789,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)EnsemblmRatBN7.2
Rnor_6.0188,977,460 - 88,990,780 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,978,344 - 88,989,552 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,132,465 - 90,145,782 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,568,846 - 85,581,069 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,147,918 - 80,160,861 (-)NCBICelera
Cytogenetic Map1q21NCBI
ARHGAP33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,775,564 - 35,788,822 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,774,532 - 35,788,822 (+)Ensemblhg38GRCh38
GRCh371936,266,466 - 36,279,724 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,958,316 - 40,971,564 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341940,958,315 - 40,971,564NCBI
Celera1932,979,892 - 32,993,199 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,771,250 - 32,784,558 (+)NCBIHuRef
CHM1_11936,267,718 - 36,281,025 (+)NCBICHM1_1
T2T-CHM13v2.01938,320,866 - 38,334,124 (+)NCBIT2T-CHM13v2.0
Arhgap33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,221,651 - 30,234,596 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,221,651 - 30,234,485 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38730,522,225 - 30,535,171 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,522,226 - 30,535,060 (-)Ensemblmm10GRCm38
MGSCv37731,307,245 - 31,320,028 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36730,230,986 - 30,243,769 (-)NCBIMGSCv36mm8
Celera725,113,538 - 25,126,798 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map718.43NCBI
Arhgap33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554682,769,493 - 2,783,155 (-)Ensembl
ChiLan1.0NW_0049554682,769,108 - 2,783,746 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,769,327 - 41,783,117 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,754,625 - 43,768,439 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,704,877 - 32,710,778 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,438,870 - 41,452,173 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,439,010 - 41,452,173 (+)EnsemblpanPan2panpan1.1
ARHGAP33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,851,341 - 116,864,696 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,851,328 - 116,864,561 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1116,256,654 - 116,269,983 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01117,454,351 - 117,467,681 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,454,358 - 117,467,680 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,017,748 - 117,031,089 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,641,363 - 116,654,689 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,696,728 - 117,710,063 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arhgap33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,092,833 - 11,106,043 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570539,830 - 553,086 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936570539,839 - 553,018 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,199,456 - 45,213,653 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1645,198,657 - 45,213,655 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,643,417 - 40,645,900 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,684,679 - 30,697,943 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,684,731 - 30,697,556 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660738,476,038 - 8,489,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479410,075,462 - 10,088,958 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479410,075,329 - 10,089,356 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgap33
17 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:9
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000034001
Prediction methods:Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)183547917128547917Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat

Markers in Region
AW324378  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2185,776,417 - 85,776,507 (+)MAPPERmRatBN7.2
Rnor_6.0188,977,757 - 88,977,846NCBIRnor6.0
Rnor_5.0190,132,762 - 90,132,851UniSTSRnor5.0
RGSC_v3.4185,568,786 - 85,568,875UniSTSRGSC3.4
Celera180,148,215 - 80,148,304UniSTS
Cytogenetic Map1q21UniSTS
RH132495  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2838,049,478 - 38,049,668 (+)MAPPERmRatBN7.2
mRatBN7.2185,776,181 - 85,776,366 (+)MAPPERmRatBN7.2
Rnor_6.0188,977,521 - 88,977,705NCBIRnor6.0
Rnor_6.0840,745,691 - 40,745,880NCBIRnor6.0
Rnor_5.0840,740,124 - 40,740,313UniSTSRnor5.0
Rnor_5.0190,132,526 - 90,132,710UniSTSRnor5.0
RGSC_v3.4185,568,550 - 85,568,734UniSTSRGSC3.4
RGSC_v3.4839,651,899 - 39,652,088UniSTSRGSC3.4
Celera836,416,128 - 36,416,317UniSTS
Celera180,147,979 - 80,148,163UniSTS
RH 3.4 Map81141.5UniSTS
Cytogenetic Map1q21UniSTS
UniSTS:235645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2838,048,541 - 38,048,781 (+)MAPPERmRatBN7.2
mRatBN7.2185,777,056 - 85,777,276 (+)MAPPERmRatBN7.2
Rnor_6.0188,978,908 - 88,979,127NCBIRnor6.0
Rnor_6.0840,744,754 - 40,744,993NCBIRnor6.0
Rnor_5.0840,739,187 - 40,739,426UniSTSRnor5.0
Rnor_5.0190,133,913 - 90,134,132UniSTSRnor5.0
RGSC_v3.4185,569,460 - 85,569,679UniSTSRGSC3.4
RGSC_v3.4839,650,962 - 39,651,201UniSTSRGSC3.4
Celera836,417,015 - 36,417,254UniSTS
Celera180,148,863 - 80,149,082UniSTS
Cytogenetic Map1q21UniSTS
MARC_4163-4164:996679454:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2185,782,059 - 85,782,488 (+)MAPPERmRatBN7.2
Rnor_6.0188,983,910 - 88,984,338NCBIRnor6.0
Rnor_5.0190,138,915 - 90,139,343UniSTSRnor5.0
RGSC_v3.4185,574,462 - 85,574,890UniSTSRGSC3.4
Celera180,153,865 - 80,154,293UniSTS
Cytogenetic Map1q21UniSTS


Related Rat Strains
The following Strains have been annotated to Arhgap33
WAG.OXYS-(D1Rat30-D1Rat219)/Nov    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 160 91 90 59 90 59 6 352 189 11 139 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001432740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003753235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034001   ⟹   ENSRNOP00000033946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl194,902,922 - 94,917,273 (-)Ensembl
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)Ensembl
Rnor_6.0 Ensembl188,978,344 - 88,989,552 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098974   ⟹   ENSRNOP00000095489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl194,902,922 - 94,917,028 (-)Ensembl
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112416   ⟹   ENSRNOP00000087660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl194,905,728 - 94,917,684 (-)Ensembl
mRatBN7.2 Ensembl185,778,283 - 85,789,678 (-)Ensembl
RefSeq Acc Id: XM_039093893   ⟹   XP_038949821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,995 (-)NCBI
mRatBN7.2185,776,112 - 85,789,706 (-)NCBI
RefSeq Acc Id: XM_039093902   ⟹   XP_038949830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,917,000 (-)NCBI
mRatBN7.2185,776,112 - 85,789,615 (-)NCBI
RefSeq Acc Id: XM_039093910   ⟹   XP_038949838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,997 (-)NCBI
mRatBN7.2185,776,112 - 85,789,615 (-)NCBI
RefSeq Acc Id: XM_039093911   ⟹   XP_038949839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,835 (-)NCBI
mRatBN7.2185,776,112 - 85,789,392 (-)NCBI
RefSeq Acc Id: XM_039093913   ⟹   XP_038949841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,908,110 - 94,917,074 (-)NCBI
mRatBN7.2185,780,666 - 85,789,713 (-)NCBI
RefSeq Acc Id: XM_063277857   ⟹   XP_063133927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,834 (-)NCBI
RefSeq Acc Id: XM_063277859   ⟹   XP_063133929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,021 (-)NCBI
RefSeq Acc Id: XM_063277862   ⟹   XP_063133932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,914,919 (-)NCBI
RefSeq Acc Id: XR_005494027
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,907,340 - 94,917,074 (-)NCBI
mRatBN7.2185,779,987 - 85,789,767 (-)NCBI
RefSeq Acc Id: XR_005494029
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,907,340 - 94,917,074 (-)NCBI
mRatBN7.2185,779,987 - 85,789,767 (-)NCBI
Ensembl Acc Id: ENSRNOP00000033946   ⟸   ENSRNOT00000034001
RefSeq Acc Id: XP_038949821   ⟸   XM_039093893
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949838   ⟸   XM_039093910
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949830   ⟸   XM_039093902
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949839   ⟸   XM_039093911
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AJS5 (UniProtKB/TrEMBL),   D4A9G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949841   ⟸   XM_039093913
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000087660   ⟸   ENSRNOT00000112416
Ensembl Acc Id: ENSRNOP00000095489   ⟸   ENSRNOT00000098974
RefSeq Acc Id: XP_063133927   ⟸   XM_063277857
- Peptide Label: isoform X3
- UniProtKB: A6J9Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133929   ⟸   XM_063277859
- Peptide Label: isoform X3
- UniProtKB: A6J9Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133932   ⟸   XM_063277862
- Peptide Label: isoform X3
- UniProtKB: A6J9Y1 (UniProtKB/TrEMBL)
Protein Domains
Rho-GAP   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9G6-F1-model_v2 AlphaFold D4A9G6 1-1310 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2318374 AgrOrtholog
BioCyc Gene G2FUF-60105 BioCyc
Ensembl Genes ENSRNOG00000024677 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034001 ENTREZGENE
  ENSRNOT00000034001.5 UniProtKB/TrEMBL
  ENSRNOT00000098974 ENTREZGENE
  ENSRNOT00000098974.1 UniProtKB/TrEMBL
  ENSRNOT00000112416.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro PX-Rho_GAP UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene 100362311 ENTREZGENE
PANTHER CDC42 GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
  PTHR15729:SF11 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Arhgap33 PhenoGen
PROSITE RHOGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024677 RatGTEx
SMART RhoGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP 64268 UniProtKB/TrEMBL
  Rho_GAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
UniProt A0A8I6A7N0_RAT UniProtKB/TrEMBL
  A0A8I6AJS5 ENTREZGENE, UniProtKB/TrEMBL
  A6J9Y1 ENTREZGENE, UniProtKB/TrEMBL
  D4A9G6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-18 Arhgap33  Rho GTPase activating protein 33  Snx26  sorting nexin 26  Data merged from RGD:1308780 737654 APPROVED
2012-08-27 Arhgap33  Rho GTPase activating protein 33  LOC100362311  sorting nexin 26  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100362311  sorting nexin 26      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Snx26  sorting nexin 26   Snx26_predicted  sorting nexin 26 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Snx26_predicted  sorting nexin 26 (predicted)      Symbol and Name status set to approved 70820 APPROVED