Mir29b2 (microRNA 29b-2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mir29b2 (microRNA 29b-2) Rattus norvegicus
Analyze
Symbol: Mir29b2
Name: microRNA 29b-2
RGD ID: 2314889
Description: Predicted to enable lncRNA binding activity; mRNA 3'-UTR binding activity; and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including negative regulation of biosynthetic process; negative regulation of signal transduction; and regulation of cell migration. Predicted to act upstream of or within several processes, including cellular hyperosmotic salinity response; cellular response to leukemia inhibitory factor; and long-term synaptic potentiation. Predicted to be located in cytoplasm; extracellular exosome; and nucleus. Orthologous to human MIR29B2 (microRNA 29b-2); INTERACTS WITH 1,2-dichloroethane; aflatoxin B1; atrazine.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-29b-2; Mir29b-2; rno-mir-29b-2
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813109,098,831 - 109,098,911 (+)NCBIGRCr8
mRatBN7.213106,570,371 - 106,570,451 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13106,570,367 - 106,570,456 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13109,087,735 - 109,087,815 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013110,471,562 - 110,471,642 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013107,696,051 - 107,696,131 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013113,782,057 - 113,782,137 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13113,782,057 - 113,782,140 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013118,329,450 - 118,329,530 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413110,967,520 - 110,967,600 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13105,994,323 - 105,994,403 (+)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular hyperosmotic salinity response  (ISO)
cellular response to leukemia inhibitory factor  (ISO)
cellular response to lipopolysaccharide  (ISO)
epigenetic regulation of gene expression  (ISO)
long-term synaptic potentiation  (ISO)
miRNA-mediated gene silencing by inhibition of translation  (ISO)
miRNA-mediated gene silencing by mRNA destabilization  (ISO)
miRNA-mediated post-transcriptional gene silencing  (ISO)
negative regulation of amyloid precursor protein catabolic process  (ISO)
negative regulation of amyloid-beta formation  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cellular response to transforming growth factor beta stimulus  (ISO)
negative regulation of circulating fibrinogen levels  (ISO)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of cytokine-mediated signaling pathway  (ISO)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of G1/S transition of mitotic cell cycle  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of interleukin-32 production  (ISO)
negative regulation of mesenchymal stem cell proliferation  (ISO)
negative regulation of non-canonical NF-kappaB signal transduction  (ISO)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway  (ISO)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
negative regulation of potassium ion transmembrane transport  (ISO)
negative regulation of Rac protein signal transduction  (ISO)
negative regulation of transforming growth factor beta receptor signaling pathway  (ISO)
negative regulation of type III interferon production  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of fat cell differentiation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of mitochondrial membrane permeability involved in apoptotic process  (ISO)
regulation of epithelium regeneration  (ISO)
regulation of membrane repolarization  (ISO)
sensory perception of sound  (ISO)
tissue remodeling  (ISO)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15345052   PMID:16381832   PMID:16766679   PMID:17028171   PMID:17604727   PMID:17805466   PMID:18723672   PMID:18762567   PMID:20403161   PMID:20439489   PMID:21522133   PMID:23646144  
PMID:24819309   PMID:25389122   PMID:25636075   PMID:25858512   PMID:26187577   PMID:26738448   PMID:28061433   PMID:30025410   PMID:30964155   PMID:31799683   PMID:32165827   PMID:33175349  
PMID:34874512   PMID:35322290   PMID:35699870   PMID:36052307  


Genomics

Comparative Map Data
Mir29b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813109,098,831 - 109,098,911 (+)NCBIGRCr8
mRatBN7.213106,570,371 - 106,570,451 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13106,570,367 - 106,570,456 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13109,087,735 - 109,087,815 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013110,471,562 - 110,471,642 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013107,696,051 - 107,696,131 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013113,782,057 - 113,782,137 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13113,782,057 - 113,782,140 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013118,329,450 - 118,329,530 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413110,967,520 - 110,967,600 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13105,994,323 - 105,994,403 (+)NCBICelera
Cytogenetic Map13q27NCBI
MIR29B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381207,802,443 - 207,802,523 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1207,802,443 - 207,802,523 (-)EnsemblGRCh38hg38GRCh38
GRCh371207,975,788 - 207,975,868 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361206,042,410 - 206,042,490 (-)NCBINCBI36Build 36hg18NCBI36
Celera1181,206,266 - 181,206,346 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1178,650,018 - 178,650,098 (-)NCBIHuRef
CHM1_11209,248,186 - 209,248,266 (-)NCBICHM1_1
T2T-CHM13v2.01207,049,202 - 207,049,282 (-)NCBIT2T-CHM13v2.0
Mir29b-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,719,348 - 194,719,428 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,719,348 - 194,719,428 (+)EnsemblGRCm39 Ensembl
GRCm381195,037,040 - 195,037,120 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,037,040 - 195,037,120 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,863,234 - 196,863,314 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1201,936,850 - 201,936,930 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map198.41NCBI
MIR29B-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,651,878 - 6,651,943 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl76,651,866 - 6,651,955 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha76,214,630 - 6,214,695 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.076,340,469 - 6,340,534 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.176,273,321 - 6,273,386 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.076,375,830 - 6,375,895 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.076,416,783 - 6,416,848 (-)NCBIUU_Cfam_GSD_1.0
MIR29B-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9135,019,075 - 135,019,164 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19135,019,079 - 135,019,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29148,552,438 - 148,552,521 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000053760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13106,570,367 - 106,570,456 (+)Ensembl
Rnor_6.0 Ensembl13113,782,057 - 113,782,140 (+)Ensembl
RefSeq Acc Id: NR_031835
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813109,098,831 - 109,098,911 (+)NCBI
mRatBN7.213106,570,371 - 106,570,451 (+)NCBI
Rnor_6.013113,782,057 - 113,782,137 (+)NCBI
Rnor_5.013118,329,450 - 118,329,530 (+)NCBI
RGSC_v3.413110,967,520 - 110,967,600 (+)RGD
Celera13105,994,323 - 105,994,403 (+)RGD
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2314889 AgrOrtholog
BioCyc Gene G2FUF-16738 BioCyc
Ensembl Genes ENSRNOG00000035637 Ensembl
miRBase MI0000862 ENTREZGENE
NCBI Gene 100314007 ENTREZGENE
PhenoGen Mir29b2 PhenoGen
RatGTEx ENSRNOG00000035637 RatGTEx
RNAcentral URS00001E96DA RNACentral
  URS000024463E RNACentral
  URS0000403C02 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir29b2  microRNA 29b-2  Mir29b-2  microRNA mir-29b-2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-04 Mir29b-2  microRNA mir-29b-2      Symbol and Name status set to provisional 70820 PROVISIONAL