Btg2 (BTG anti-proliferation factor 2) - Rat Genome Database

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Gene: Btg2 (BTG anti-proliferation factor 2) Rattus norvegicus
Analyze
Symbol: Btg2
Name: BTG anti-proliferation factor 2
RGD ID: 2225
Description: Exhibits transcription corepressor activity. Involved in several processes, including negative regulation of neuron apoptotic process; negative regulation of transcription by RNA polymerase II; and response to electrical stimulus. Predicted to localize to cytoplasm and nucleus. Biomarker of brain ischemia. Orthologous to human BTG2 (BTG anti-proliferation factor 2); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate; 1-nitropropane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Agl; An; an-1; B-cell translocation gene 2; B-cell translocation gene 2 anti-proliferative; B-cell translocation gene 2, anti-proliferative; BTG family, member 2; cell surface alloantigen; Early induced gene B-cell translocation gene 2; NGF-inducible anti-proliferative protein PC3; NGF-inducible anti-proliferative putative secreted protein; PC3; Tis21
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Btg2em11Mcwi   Btg2em13Mcwi   Btg2em7Mcwi   Btg2em21Mcwi   Btg2em24Mcwi  
Genetic Models: SS.BN-(D13Rat25-rs106935835)-Btg2em11Mcwi SS.BN-(D13Rat25-rs106935835)-Btg2em13Mcwi SS.BN-(D13Rat25-rs198199323)-Btg2em24Mcwi SS.BN-(D13Rat25-rs198199323)-Btg2em21Mcwi SS.BN-(D13Rat25-rs106935835)-Btg2em7Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21345,531,881 - 45,535,642 (-)NCBI
Rnor_6.0 Ensembl1350,913,180 - 50,916,982 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01350,913,185 - 50,916,944 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01355,966,299 - 55,970,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,026,986 - 47,030,745 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11347,041,028 - 47,044,788 (-)NCBI
Celera1345,860,186 - 45,864,450 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropropane  (EXP)
15-acetyldeoxynivalenol  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-diaminotoluene  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-diaminotoluene  (EXP)
2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one  (EXP)
2-acetamidofluorene  (EXP,ISO)
2-arachidonoylglycerol  (ISO)
2-nitro-p-phenylenediamine  (EXP)
2-nitrofluorene  (EXP)
2-nitropropane  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-acetylaminofluorene  (EXP)
4-nitro-1,2-phenylenediamine  (EXP)
4-vinylcyclohexene dioxide  (ISO)
5-fluorouracil  (ISO)
6-O-methylguanine  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
adefovir pivoxil  (ISO)
adenine  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
alvocidib  (ISO)
AM-251  (ISO)
ammonium chloride  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bexarotene  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brevetoxin B  (ISO)
buspirone  (EXP)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
cefaloridine  (EXP)
chloroacetaldehyde  (ISO)
chloroform  (EXP,ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chromium(3+) trichloride  (ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
corticosterone  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cytarabine  (ISO)
DDE  (ISO)
DDT  (EXP)
delphinidin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorvos  (EXP)
dieldrin  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (EXP,ISO)
dimethyl sulfoxide  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
erythromycin estolate  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenamidone  (ISO)
fenofibrate  (EXP)
fluoranthene  (ISO)
flusilazole  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycidol  (EXP)
Goe 6976  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxyurea  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
leptomycin B  (ISO)
lipopolysaccharide  (EXP,ISO)
melatonin  (ISO)
melphalan  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (EXP)
metacetamol  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
myristicin  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N-Nitrosopyrrolidine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naphthalenes  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenethyl isothiocyanate  (EXP)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
potassium chloride  (ISO)
progesterone  (EXP)
propanal  (ISO)
quercetin  (ISO)
quinomethionate  (ISO)
ranitidine  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
succimer  (ISO)
sulforaphane  (ISO)
tacrolimus hydrate  (EXP)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tungsten  (ISO)
undecane  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. Altin JG, etal., J Biol Chem. 1991 Mar 25;266(9):5401-6.
2. Bradbury A, etal., Proc Natl Acad Sci U S A 1991 Apr 15;88(8):3353-7.
3. Carmel JB, etal., Exp Neurol. 2004 Jan;185(1):81-96.
4. Cho Y, etal., Brain Res Mol Brain Res. 2004 Nov 4;130(1-2):134-48.
5. Corrente G, etal., Neuroreport 2002 Mar 25;13(4):417-22.
6. el-Ghissassi F, etal., Oncogene. 2002 Oct 3;21(44):6772-78.
7. Farioli-Vecchioli S, etal., PLoS One. 2009 Dec 17;4(12):e8339. doi: 10.1371/journal.pone.0008339.
8. Ficazzola MA, etal., Carcinogenesis. 2001 Aug;22(8):1271-9.
9. Fiedler F, etal., Biochem Biophys Res Commun. 1998 Aug 19;249(2):562-5.
10. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. Guardavaccaro D, etal., Mol Cell Biol 2000 Mar;20(5):1797-815.
12. Gubits RM, etal., Brain Res Mol Brain Res. 1993 May;18(3):228-38.
13. Hoffman MJ, etal., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1.
14. Jung HY, etal., Biol Psychiatry. 1996 Sep 15;40(6):503-7.
15. Kawakubo H, etal., Cancer Res. 2006 Jul 15;66(14):7075-82.
16. Lin WJ, etal., Biochem J 2001 Mar 15;354(Pt 3):635-43.
17. Luyendyk JP, etal., Toxicol Sci. 2004 Jul;80(1):203-13. Epub 2004 Apr 14.
18. Montagnoli A, etal., Cell Growth Differ 1996 Oct;7(10):1327-36.
19. NCBI rat LocusLink and RefSeq merged data July 26, 2002
20. Pipeline to import KEGG annotations from KEGG into RGD
21. RGD automated data pipeline
22. RGD automated import pipeline for gene-chemical interactions
23. RGD comprehensive gene curation
24. Shao J, etal., Int J Biochem Cell Biol. 2012 Dec;44(12):2253-60. doi: 10.1016/j.biocel.2012.09.013. Epub 2012 Sep 20.
25. Simkhovich BZ, etal., Cardiovasc Res. 2003 Aug 1;59(2):450-9.
26. Stephenson SP, etal., J Immunogenet 1985 Apr;12(2):101-14.
27. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
28. Struckmann K, etal., Cancer Res. 2004 Mar 1;64(5):1632-8.
29. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
30. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
31. Tirone F J Cell Physiol 2001 May;187(2):155-65.
32. Varnum BC, etal., J Cell Physiol. 1994 Jan;158(1):205-13.
33. Yamada J, etal., Mamm Genome 1994 Feb;5(2):63-83.
Additional References at PubMed
PMID:7811636   PMID:8663146   PMID:8944033   PMID:15056715   PMID:15489334   PMID:15542835   PMID:16191397   PMID:16335396   PMID:17032584   PMID:17371797   PMID:18337750   PMID:18773938  
PMID:19056867   PMID:19359386   PMID:19997037   PMID:22147266   PMID:23058912   PMID:23236473   PMID:23267836   PMID:23703573   PMID:27333946  


Genomics

Candidate Gene Status
Btg2 is a candidate Gene for QTL Bp398
Comparative Map Data
Btg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21345,531,881 - 45,535,642 (-)NCBI
Rnor_6.0 Ensembl1350,913,180 - 50,916,982 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01350,913,185 - 50,916,944 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01355,966,299 - 55,970,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,026,986 - 47,030,745 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11347,041,028 - 47,044,788 (-)NCBI
Celera1345,860,186 - 45,864,450 (-)NCBICelera
Cytogenetic Map13q13NCBI
BTG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1203,305,491 - 203,309,602 (+)EnsemblGRCh38hg38GRCh38
GRCh381203,305,519 - 203,309,602 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,274,647 - 203,278,730 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,541,287 - 201,545,353 (+)NCBINCBI36hg18NCBI36
Build 341200,006,320 - 200,010,384NCBI
Celera1176,403,938 - 176,408,003 (+)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,439,723 - 174,443,788 (+)NCBIHuRef
CHM1_11204,697,045 - 204,701,100 (+)NCBICHM1_1
Btg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,002,603 - 134,006,893 (-)NCBIGRCm39mm39
GRCm39 Ensembl1134,002,908 - 134,006,858 (-)Ensembl
GRCm381134,074,865 - 134,079,155 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,075,170 - 134,079,120 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,971,442 - 135,975,732 (-)NCBIGRCm37mm9NCBIm37
MGSCv361135,891,276 - 135,895,566 (-)NCBImm8
Celera1136,692,103 - 136,696,393 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.1NCBI
Btg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,303,175 - 39,308,778 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,303,221 - 39,307,308 (+)NCBIChiLan1.0ChiLan1.0
BTG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11183,201,297 - 183,205,404 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1183,201,297 - 183,205,404 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01178,907,317 - 178,911,410 (+)NCBIMhudiblu_PPA_v0panPan3
BTG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13870,921 - 75,149 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3870,452 - 72,976 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha38161,110 - 165,136 (+)NCBI
ROS_Cfam_1.03867,926 - 71,934 (+)NCBI
UMICH_Zoey_3.13860,447 - 64,469 (+)NCBI
UNSW_CanFamBas_1.038454,515 - 458,533 (+)NCBI
UU_Cfam_GSD_1.038668,563 - 672,594 (+)NCBI
Btg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,075,888 - 72,079,831 (-)NCBI
SpeTri2.0NW_0049365671,310,525 - 1,314,469 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BTG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1964,033,853 - 64,037,795 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2970,327,454 - 70,331,396 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9q21-q25NCBI
BTG2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,032,404 - 26,036,500 (-)NCBI
ChlSab1.1 Ensembl2526,034,632 - 26,036,538 (-)Ensembl
Btg2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248077,541,335 - 7,545,412 (-)NCBI

Position Markers
AA819837  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,533,782 - 45,533,932 (+)MAPPER
Rnor_6.01350,915,087 - 50,915,236NCBIRnor6.0
Rnor_5.01355,968,201 - 55,968,350UniSTSRnor5.0
RGSC_v3.41347,028,888 - 47,029,037UniSTSRGSC3.4
Celera1345,862,088 - 45,862,237UniSTS
RH 3.4 Map13178.1UniSTS
Cytogenetic Map13q13-q31UniSTS
PMC156147P12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,533,920 - 45,534,013 (+)MAPPER
Rnor_6.01350,915,225 - 50,915,317NCBIRnor6.0
Rnor_5.01355,968,339 - 55,968,431UniSTSRnor5.0
RGSC_v3.41347,029,026 - 47,029,118UniSTSRGSC3.4
Celera1345,862,226 - 45,862,318UniSTS
Cytogenetic Map13q13-q31UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131409633059096330Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131409633059096330Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131444158251577031Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131981081464810814Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)132005247765052477Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132148248158537177Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132800833873008338Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132858445273584452Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133614753364868393Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134877665553264877Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134905850767207219Rat
12879436Bp395Blood pressure QTL 395arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134999470851081193Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135060922853264877Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135089609150918009Rat


Genetic Models
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:685
Count of miRNA genes:275
Interacting mature miRNAs:353
Transcripts:ENSRNOT00000004408
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 44 28 19 28 6 9 56 30 33 11 6
Low 13 13 13 2 2 18 5 8 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004408   ⟹   ENSRNOP00000004408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1350,913,180 - 50,916,982 (-)Ensembl
RefSeq Acc Id: NM_017259   ⟹   NP_058955
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21345,531,881 - 45,535,642 (-)NCBI
Rnor_6.01350,913,185 - 50,916,944 (-)NCBI
Rnor_5.01355,966,299 - 55,970,058 (-)NCBI
RGSC_v3.41347,026,986 - 47,030,745 (-)RGD
Celera1345,860,186 - 45,864,450 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058955 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB49567 (Get FASTA)   NCBI Sequence Viewer  
  AAH72493 (Get FASTA)   NCBI Sequence Viewer  
  EDM09744 (Get FASTA)   NCBI Sequence Viewer  
  P27049 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058955   ⟸   NM_017259
- UniProtKB: P27049 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004408   ⟸   ENSRNOT00000004408

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698825
Promoter ID:EPDNEW_R9350
Type:single initiation site
Name:Btg2_1
Description:BTG anti-proliferation factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01350,916,944 - 50,917,004EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2225 AgrOrtholog
BIND 130432
  130434
Ensembl Genes ENSRNOG00000003300 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000004408 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004408 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.1120 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7097327 IMAGE-MGC_LOAD
InterPro Anti_prolifrtn UniProtKB/Swiss-Prot
  BTG UniProtKB/Swiss-Prot
  BTG-like_sf UniProtKB/Swiss-Prot
  BTG2 UniProtKB/Swiss-Prot
KEGG Report rno:29619 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91753 IMAGE-MGC_LOAD
NCBI Gene 29619 ENTREZGENE
PANTHER PTHR22978 UniProtKB/Swiss-Prot
  PTHR22978:SF29 UniProtKB/Swiss-Prot
Pfam BTG UniProtKB/Swiss-Prot
PhenoGen Btg2 PhenoGen
PRINTS ANTIPRLFBTG1 UniProtKB/Swiss-Prot
PROSITE BTG_1 UniProtKB/Swiss-Prot
  BTG_2 UniProtKB/Swiss-Prot
SMART btg1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF160696 UniProtKB/Swiss-Prot
TIGR TC217033
UniProt BTG2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-13 Btg2  BTG anti-proliferation factor 2  Btg2  BTG family, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-04 Btg2  BTG family, member 2  Btg2  B-cell translocation gene 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-11-05 Btg2  B-cell translocation gene 2  Btg2  B-cell translocation gene 2, anti-proliferative  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Btg2  B-cell translocation gene 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease mutations in mouse homolog result in symptoms of mild to severe anemia 1300183
gene_function interacts with Pick1, a protein kinase C-alpha-binding protein 68719
gene_process may be involved in mitogenic responses, differentiation, and cell death 68719
gene_process has a role in cellular differentiation 1298588
gene_process may act as a transcriptional co-regulator 1298712
gene_product member of a novel family of antiproliferative genes 1298588
gene_regulation a p53-inducible gene 1298713