Bsn (bassoon (presynaptic cytomatrix protein)) - Rat Genome Database

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Gene: Bsn (bassoon (presynaptic cytomatrix protein)) Rattus norvegicus
Analyze
Symbol: Bsn
Name: bassoon (presynaptic cytomatrix protein)
RGD ID: 2223
Description: Enables dynein light chain binding activity; enzyme inhibitor activity; and transcription corepressor binding activity. Involved in several processes, including presynaptic active zone assembly; regulation of ubiquitin protein ligase activity; and retrograde axonal transport. Located in several cellular components, including axon cytoplasm; cytoplasmic vesicle; and cytoskeleton of presynaptic active zone. Is active in several cellular components, including GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; and presynaptic active zone cytoplasmic component. Orthologous to human BSN (bassoon presynaptic cytomatrix protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bassoon; neuronal double zinc finger protein; zinc finger protein 231; Znf231
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Bsnem1Ionsz  
Genetic Models: SD-Bsnem1Ionsz
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,663,447 - 117,754,412 (-)NCBIGRCr8
mRatBN7.28108,784,849 - 108,875,819 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,788,542 - 108,875,819 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,411,051 - 114,502,023 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,610,375 - 112,701,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,453,016 - 110,543,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,873,721 - 116,965,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,873,721 - 116,965,396 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,227,802 - 116,319,071 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,364,208 - 113,455,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,387,192 - 113,475,221 (-)NCBI
Celera8108,089,061 - 108,180,178 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif. Burkhardt C, etal., FEBS Lett. 2005 Jul 4;579(17):3821-8.
2. Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with Bassoon. Dick O, etal., J Comp Neurol. 2001 Oct 15;439(2):224-34.
3. Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment. Dresbach T, etal., J Biol Chem. 2006 Mar 3;281(9):6038-47. Epub 2005 Dec 21.
4. Myotonia congenita with strabismus in a large family with a mutation in the SCN4A gene. Du H, etal., Eye (Lond). 2012 Aug;26(8):1039-43. doi: 10.1038/eye.2012.80. Epub 2012 Jun 1.
5. Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. Fejtova A, etal., J Cell Biol. 2009 Apr 20;185(2):341-55. doi: 10.1083/jcb.200807155.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. Ivanova D, etal., EMBO J. 2015 Apr 15;34(8):1056-77. doi: 10.15252/embj.201488796. Epub 2015 Feb 4.
9. Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation. Ko J, etal., EMBO J. 2009 Oct 21;28(20):3244-55. doi: 10.1038/emboj.2009.249. Epub 2009 Sep 3.
10. Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover. Körber C, etal., Neuron. 2015 Aug 5;87(3):521-33. doi: 10.1016/j.neuron.2015.07.001. Epub 2015 Jul 23.
11. Formation of Golgi-derived active zone precursor vesicles. Maas C, etal., J Neurosci. 2012 Aug 8;32(32):11095-108. doi: 10.1523/JNEUROSCI.0195-12.2012.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1. Ohtsuka T, etal., J Cell Biol 2002 Aug 5;158(3):577-90. Epub 2002 Aug 5.
15. D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone. Popiolek M, etal., J Biol Chem. 2011 Aug 19;286(33):28867-28875. doi: 10.1074/jbc.M111.262063. Epub 2011 Jun 23.
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Presynaptic cytomatrix protein bassoon is localized at both excitatory and inhibitory synapses of rat brain. Richter K, etal., J Comp Neurol. 1999 Jun 7;408(3):437-48.
20. Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals. tom Dieck S, etal., J Cell Biol 1998 Jul 27;142(2):499-509.
21. Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation. Waites CL, etal., EMBO J. 2013 Apr 3;32(7):954-69. doi: 10.1038/emboj.2013.27. Epub 2013 Feb 12.
Additional References at PubMed
PMID:8889548   PMID:10564375   PMID:10900017   PMID:12115694   PMID:12812759   PMID:14622577   PMID:14734538   PMID:15340146   PMID:15935055   PMID:17114649   PMID:19966281   PMID:20127803  
PMID:21092860   PMID:21144999   PMID:21356198   PMID:21712437   PMID:21940441   PMID:22701595   PMID:22871113   PMID:23516560   PMID:23791195   PMID:24554721   PMID:26793095   PMID:27907191  
PMID:29476059   PMID:30053369   PMID:32651614  


Genomics

Comparative Map Data
Bsn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,663,447 - 117,754,412 (-)NCBIGRCr8
mRatBN7.28108,784,849 - 108,875,819 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,788,542 - 108,875,819 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,411,051 - 114,502,023 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,610,375 - 112,701,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,453,016 - 110,543,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,873,721 - 116,965,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,873,721 - 116,965,396 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,227,802 - 116,319,071 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,364,208 - 113,455,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,387,192 - 113,475,221 (-)NCBI
Celera8108,089,061 - 108,180,178 (-)NCBICelera
Cytogenetic Map8q32NCBI
BSN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38349,554,477 - 49,673,130 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl349,554,477 - 49,671,549 (+)EnsemblGRCh38hg38GRCh38
GRCh37349,591,910 - 49,708,982 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,566,926 - 49,683,986 (+)NCBINCBI36Build 36hg18NCBI36
Build 34349,566,925 - 49,683,980NCBI
Celera349,556,534 - 49,673,679 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef349,651,449 - 49,767,966 (+)NCBIHuRef
CHM1_1349,544,319 - 49,661,041 (+)NCBICHM1_1
T2T-CHM13v2.0349,583,475 - 49,700,809 (+)NCBIT2T-CHM13v2.0
Bsn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,973,221 - 108,067,618 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,973,221 - 108,067,583 (-)EnsemblGRCm39 Ensembl
GRCm389108,096,022 - 108,190,419 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,096,022 - 108,190,384 (-)EnsemblGRCm38mm10GRCm38
MGSCv379107,998,353 - 108,092,714 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,961,291 - 108,048,359 (-)NCBIMGSCv36mm8
Celera9107,705,791 - 107,798,925 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map959.07NCBI
Bsn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,527,477 - 1,570,670 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,527,336 - 1,578,394 (+)NCBIChiLan1.0ChiLan1.0
BSN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2249,537,981 - 49,653,399 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1349,542,626 - 49,663,680 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0349,483,652 - 49,603,928 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1350,729,927 - 50,841,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,790,552 - 50,841,178 (+)Ensemblpanpan1.1panPan2
BSN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,601,803 - 39,696,831 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,605,117 - 39,642,298 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2039,519,615 - 39,562,116 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02039,956,213 - 39,998,718 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2039,956,214 - 40,053,096 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,323,297 - 39,368,646 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02039,726,652 - 39,770,208 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,006,478 - 40,050,065 (-)NCBIUU_Cfam_GSD_1.0
Bsn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560264,422,347 - 64,527,292 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365291,182,810 - 1,280,657 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365291,182,872 - 1,287,794 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BSN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,159,630 - 32,195,578 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,106,967 - 32,203,461 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,341,713 - 35,382,661 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BSN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,953,901 - 11,066,892 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,018,966 - 11,059,701 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041155,934,160 - 156,048,808 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bsn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,498,257 - 3,593,450 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247303,498,118 - 3,600,488 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bsn
336 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:416
Count of miRNA genes:220
Interacting mature miRNAs:281
Transcripts:ENSRNOT00000042528
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
D8Rat67  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,836,661 - 108,836,849 (+)MAPPERmRatBN7.2
Rnor_6.08116,926,242 - 116,926,429NCBIRnor6.0
Rnor_5.08116,279,875 - 116,280,062UniSTSRnor5.0
RGSC_v3.48113,416,613 - 113,416,800UniSTSRGSC3.4
RGSC_v3.48113,416,429 - 113,416,799RGDRGSC3.4
RGSC_v3.18113,435,884 - 113,436,254RGD
Celera8108,140,920 - 108,141,107UniSTS
RH 3.4 Map81118.6UniSTS
RH 3.4 Map81118.6RGD
RH 2.0 Map8874.3RGD
SHRSP x BN Map871.8999RGD
Cytogenetic Map8q32UniSTS
D8Wox32  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,793,202 - 108,793,463 (+)MAPPERmRatBN7.2
Rnor_6.08116,882,075 - 116,882,335NCBIRnor6.0
Rnor_5.08116,236,156 - 116,236,416UniSTSRnor5.0
RGSC_v3.48113,372,562 - 113,372,826UniSTSRGSC3.4
Celera8108,097,417 - 108,097,677UniSTS
Cytogenetic Map8q32UniSTS
BF387500  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,786,414 - 108,786,571 (+)MAPPERmRatBN7.2
Rnor_6.08116,875,287 - 116,875,443NCBIRnor6.0
Rnor_5.08116,229,368 - 116,229,524UniSTSRnor5.0
RGSC_v3.48113,365,774 - 113,365,930UniSTSRGSC3.4
Celera8108,090,629 - 108,090,785UniSTS
RH 3.4 Map81116.7UniSTS
Cytogenetic Map8q32UniSTS
BE097610  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,790,188 - 108,790,380 (+)MAPPERmRatBN7.2
Rnor_6.08116,879,061 - 116,879,252NCBIRnor6.0
Rnor_5.08116,233,142 - 116,233,333UniSTSRnor5.0
RGSC_v3.48113,369,548 - 113,369,739UniSTSRGSC3.4
Celera8108,094,403 - 108,094,594UniSTS
RH 3.4 Map81120.9UniSTS
Cytogenetic Map8q32UniSTS
D8Wox11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,784,680 - 108,784,789 (+)MAPPERmRatBN7.2
Rnor_6.08116,873,553 - 116,873,661NCBIRnor6.0
Rnor_5.08116,227,634 - 116,227,742UniSTSRnor5.0
RGSC_v3.48113,364,040 - 113,364,148UniSTSRGSC3.4
Celera8108,088,893 - 108,089,001UniSTS
Cytogenetic Map8q32UniSTS


Genetic Models
This gene Bsn is modified in the following models/strains:


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 46 113 74 73 42 25 42 6 191 92 93 41 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000042528   ⟹   ENSRNOP00000039162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl8116,873,721 - 116,965,396 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082113   ⟹   ENSRNOP00000072024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8108,788,542 - 108,875,819 (-)Ensembl
Rnor_6.0 Ensembl8116,877,251 - 116,893,057 (-)Ensembl
RefSeq Acc Id: NM_019146   ⟹   NP_062019
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88117,663,447 - 117,754,412 (-)NCBI
mRatBN7.28108,784,849 - 108,875,819 (-)NCBI
Rnor_6.08116,873,721 - 116,965,396 (-)NCBI
Rnor_5.08116,227,802 - 116,319,071 (-)NCBI
RGSC_v3.48113,364,208 - 113,455,766 (-)RGD
Celera8108,089,061 - 108,180,178 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_062019 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA76287 (Get FASTA)   NCBI Sequence Viewer  
  EDL77188 (Get FASTA)   NCBI Sequence Viewer  
  EDL77189 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072024.2
GenBank Protein O88778 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062019   ⟸   NM_019146
- UniProtKB: O88778 (UniProtKB/Swiss-Prot),   G3V984 (UniProtKB/TrEMBL),   A6I338 (UniProtKB/TrEMBL),   A0A0G2K1X6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072024   ⟸   ENSRNOT00000082113
Ensembl Acc Id: ENSRNOP00000039162   ⟸   ENSRNOT00000042528
Protein Domains
Zinc finger piccolo-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696291
Promoter ID:EPDNEW_R6816
Type:single initiation site
Name:Bsn_1
Description:bassoon
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08116,965,404 - 116,965,464EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2223 AgrOrtholog
BioCyc Gene G2FUF-29156 BioCyc
Ensembl Genes ENSRNOG00000030714 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082113.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Bsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Presynaptic_Scaffold_Bsn/Pclo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_piccolo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29138 UniProtKB/TrEMBL
NCBI Gene 29138 ENTREZGENE
PANTHER PICCOLO/BASSOON UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14113:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-piccolo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bsn PhenoGen
RatGTEx ENSRNOG00000030714 RatGTEx
Superfamily-SCOP SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K1X6 ENTREZGENE, UniProtKB/TrEMBL
  A6I338 ENTREZGENE, UniProtKB/TrEMBL
  BSN_RAT UniProtKB/Swiss-Prot
  G3V984 ENTREZGENE
  O88778 ENTREZGENE
UniProt Secondary G3V984 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-14 Bsn  bassoon (presynaptic cytomatrix protein)  Bsn  bassoon  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Bsn  bassoon      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the axon terminals of hippocampal neurons 69780
gene_cellular_localization presynaptic cytomatrix protein 69780
gene_domains contains two double-zinc fingers, several coiled-coil domains, and a stretch of polyglutamines 69780