(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BRCA1 mRNA] CTD PMID:31150632 (-)-alpha-phellandrene decreases expression ISO RGD:10246 6480464 alpha phellandrene results in decreased expression of BRCA1 protein CTD PMID:24861204 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:69132 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of BRCA1 mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate increases expression ISO RGD:69132 6480464 epigallocatechin gallate results in increased expression of BRCA1 mRNA CTD PMID:25839702 (S)-naringenin multiple interactions ISO RGD:69132 6480464 [naringenin co-treated with bisphenol A] results in increased expression of BRCA1 mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of BRCA1 mRNA CTD PMID:36235125 (S)-nicotine decreases expression ISO RGD:69132 6480464 Nicotine results in decreased expression of BRCA1 mRNA CTD PMID:18247414 (S)-nicotine multiple interactions ISO RGD:69132 6480464 Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of BRCA1 protein modified form] CTD PMID:23907605 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:69132 6480464 o, p'-DDT results in increased expression of BRCA1 mRNA CTD PMID:20206645 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO RGD:69132 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [o more ... CTD PMID:20206645 1,1-dichloroethene increases expression ISO RGD:10246 6480464 vinylidene chloride results in increased expression of BRCA1 mRNA CTD PMID:26682919 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of BRCA1 mRNA CTD PMID:30723492 1-nitropyrene decreases expression ISO RGD:69132 6480464 1-nitropyrene results in decreased expression of BRCA1 mRNA CTD PMID:21540303 17beta-estradiol increases expression ISO RGD:10246 6480464 Estradiol results in increased expression of BRCA1 mRNA CTD PMID:25210133 17beta-estradiol decreases expression ISO RGD:69132 6480464 Estradiol results in decreased expression of BRCA1 mRNA CTD PMID:23373633 17beta-estradiol increases expression ISO RGD:69132 6480464 Estradiol results in increased expression of BRCA1 mRNA, Estradiol results in increased expression of BRCA1 protein CTD PMID:12473173 more ... 17beta-estradiol affects localization ISO RGD:69132 6480464 Estradiol affects the localization of BRCA1 protein CTD PMID:16061635 17beta-estradiol multiple interactions ISO RGD:69132 6480464 2 more ... CTD PMID:11110848 more ... 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:69132 6480464 Metribolone results in increased expression of BRCA1 mRNA CTD PMID:17010196 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:69132 6480464 2 more ... CTD PMID:12473173 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:20566336 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10246 6480464 [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of BRCA1 mRNA CTD PMID:21167638 2,3,7,8-tetrachlorodibenzodioxine increases methylation ISO RGD:69132 6480464 Tetrachlorodibenzodioxin results in increased methylation of BRCA1 promoter CTD PMID:22197621 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69132 6480464 Tetrachlorodibenzodioxin results in decreased expression of BRCA1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of BRCA1 protein CTD PMID:20631324 , PMID:22197621 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:69132 6480464 Tetrachlorodibenzodioxin affects the expression of BRCA1 mRNA CTD PMID:22298810 , PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine increases methylation EXP 6480464 Tetrachlorodibenzodioxin results in increased methylation of BRCA1 promoter CTD PMID:24136580 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of BRCA1 mRNA CTD PMID:22298810 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of BRCA1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of BRCA1 protein CTD PMID:24136580 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 BRCA1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] more ... CTD PMID:16567799 , PMID:24136580 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10246 6480464 Tetrachlorodibenzodioxin results in increased expression of BRCA1 mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:69132 6480464 [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] promotes the reaction [AHR protein binds to BRCA1 promoter]] inhibits the reaction [Estradiol results in increased expression of BRCA1 mRNA] more ... CTD PMID:12473173 more ... 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of BRCA1 mRNA CTD PMID:19167416 2-butoxyethanol increases expression ISO RGD:10246 6480464 n-butoxyethanol results in increased expression of BRCA1 mRNA CTD PMID:19812364 2-methylcholine affects expression ISO RGD:69132 6480464 beta-methylcholine affects the expression of BRCA1 mRNA CTD PMID:21179406 2-naphthylamine decreases expression ISO RGD:69132 6480464 2-Naphthylamine results in decreased expression of BRCA1 mRNA CTD PMID:18247414 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3-methylcholanthrene multiple interactions ISO RGD:69132 6480464 Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein] CTD PMID:18259752 3-methylcholanthrene increases expression ISO RGD:10246 6480464 Methylcholanthrene results in increased expression of BRCA1 mRNA CTD PMID:20713471 4,4'-sulfonyldiphenol multiple interactions ISO RGD:69132 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in increased methylation of BRCA1 gene CTD PMID:31601247 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO RGD:10246 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BRCA1 mRNA CTD PMID:21167638 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:10246 6480464 [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of BRCA1 mRNA CTD PMID:21167638 5-aza-2'-deoxycytidine affects localization ISO RGD:69132 6480464 Decitabine affects the localization of BRCA1 protein modified form CTD PMID:17991895 5-fluorouracil increases expression ISO RGD:69132 6480464 Fluorouracil results in increased expression of BRCA1 mRNA CTD PMID:16101138 , PMID:16557594 5-fluorouracil decreases expression ISO RGD:69132 6480464 Fluorouracil results in decreased expression of BRCA1 mRNA CTD PMID:15607317 , PMID:17982676 5-fluorouracil multiple interactions ISO RGD:69132 6480464 TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA] CTD PMID:17982676 7,12-dimethyltetraphene affects response to substance ISO RGD:69132 6480464 BRCA1 protein affects the susceptibility to 9 more ... CTD PMID:21507987 7,12-dimethyltetraphene increases expression ISO RGD:10246 6480464 9 more ... CTD PMID:25448685 7,12-dimethyltetraphene multiple interactions ISO RGD:10246 6480464 9 more ... CTD PMID:25448685 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:23969067 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression ISO RGD:10246 6480464 Uric Acid results in decreased expression of BRCA1 mRNA CTD PMID:23619996 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:10246 6480464 NLRP3 gene mutant form inhibits the reaction [Uric Acid results in decreased expression of BRCA1 mRNA] CTD PMID:23619996 8-hydroxy-2'-deoxyguanosine multiple interactions ISO RGD:10246 6480464 [BRCA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:26629949 acetamide increases expression EXP 6480464 acetamide results in increased expression of BRCA1 mRNA CTD PMID:31881176 acetylsalicylic acid decreases expression ISO RGD:69132 6480464 Aspirin results in decreased expression of BRCA1 mRNA CTD PMID:20457246 , PMID:20514442 acrolein multiple interactions ISO RGD:69132 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of BRCA1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of BRCA1 mRNA CTD PMID:32699268 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of BRCA1 mRNA CTD PMID:28606764 Aflatoxin G1 increases activity ISO RGD:69132 6480464 aflatoxin G1 results in increased activity of BRCA1 protein CTD PMID:23907605 Aflatoxin G1 increases expression ISO RGD:69132 6480464 aflatoxin G1 results in increased expression of BRCA1 protein modified form CTD PMID:23907605 Aflatoxin G1 multiple interactions ISO RGD:69132 6480464 Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of BRCA1 protein modified form], Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of BRCA1 protein modified form] CTD PMID:23907605 all-trans-retinoic acid increases expression ISO RGD:69132 6480464 Tretinoin results in increased expression of BRCA1 mRNA CTD PMID:16054129 all-trans-retinoic acid decreases expression ISO RGD:69132 6480464 Tretinoin results in decreased expression of BRCA1 mRNA CTD PMID:15498508 , PMID:33167477 all-trans-retinoic acid increases expression ISO RGD:10246 6480464 Tretinoin results in increased expression of BRCA1 mRNA CTD PMID:17198874 allethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of BRCA1 protein CTD PMID:34896426 alpha-naphthoflavone multiple interactions ISO RGD:69132 6480464 alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein], alpha-naphthoflavone inhibits the reaction [Estradiol results in increased expression of BRCA1 mRNA] CTD PMID:16489025 , PMID:18259752 alpha-phellandrene decreases expression ISO RGD:10246 6480464 alpha phellandrene results in decreased expression of BRCA1 protein CTD PMID:24861204 alpha-pinene multiple interactions ISO RGD:69132 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of BRCA1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of BRCA1 mRNA CTD PMID:32699268 amiodarone increases expression ISO RGD:10246 6480464 Amiodarone results in increased expression of BRCA1 mRNA CTD PMID:24489787 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of BRCA1 mRNA CTD PMID:16483693 arecoline decreases expression ISO RGD:69132 6480464 Arecoline results in decreased expression of BRCA1 mRNA CTD PMID:17682004 arsane affects methylation ISO RGD:69132 6480464 Arsenic affects the methylation of BRCA1 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:69132 6480464 Arsenic affects the methylation of BRCA1 gene CTD PMID:25304211 arsenite(3-) decreases expression ISO RGD:69132 6480464 arsenite results in decreased expression of BRCA1 mRNA CTD PMID:31646340 arsenous acid increases expression ISO RGD:69132 6480464 Arsenic Trioxide results in increased expression of BRCA1 mRNA CTD PMID:20458559 asbestos affects response to substance ISO RGD:69132 6480464 BRCA1 alternative form affects the susceptibility to Asbestos CTD PMID:28687356 atrazine decreases expression ISO RGD:69132 6480464 Atrazine results in decreased expression of BRCA1 mRNA CTD PMID:22378314 benzo[a]pyrene multiple interactions ISO RGD:69132 6480464 ARNT protein affects the reaction [BRCA1 protein affects the susceptibility to Benzo(a)pyrene] more ... CTD PMID:11782367 more ... benzo[a]pyrene affects methylation ISO RGD:69132 6480464 Benzo(a)pyrene affects the methylation of BRCA1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:69132 6480464 Benzo(a)pyrene results in decreased expression of BRCA1 mRNA CTD PMID:11782367 more ... benzo[a]pyrene increases expression ISO RGD:69132 6480464 Benzo(a)pyrene results in increased expression of BRCA1 mRNA CTD PMID:28461126 more ... benzo[a]pyrene affects response to substance ISO RGD:10246 6480464 BRCA1 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:21507987 benzo[a]pyrene increases expression ISO RGD:10246 6480464 Benzo(a)pyrene results in increased expression of BRCA1 mRNA CTD PMID:20713471 benzo[a]pyrene decreases expression ISO RGD:10246 6480464 Benzo(a)pyrene results in decreased expression of BRCA1 mRNA CTD PMID:17942131 benzo[a]pyrene affects response to substance ISO RGD:69132 6480464 BRCA1 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:21507987 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:69132 6480464 TP53 protein promotes the reaction [7 more ... CTD PMID:11782367 benzo[a]pyrene diol epoxide I affects expression ISO RGD:69132 6480464 7 more ... CTD PMID:34454013 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:69132 6480464 7 more ... CTD PMID:11782367 , PMID:20382639 benzophenanthridine decreases expression ISO RGD:69132 6480464 Benzophenanthridines analog results in decreased expression of BRCA1 mRNA CTD PMID:23117580 beta-hexachlorocyclohexane multiple interactions ISO RGD:69132 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of BRCA1 mRNA], fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of BRCA1 mRNA] CTD PMID:20206645 beta-hexachlorocyclohexane increases expression ISO RGD:69132 6480464 beta-hexachlorocyclohexane results in increased expression of BRCA1 mRNA CTD PMID:20206645 bifenthrin affects binding ISO RGD:69132 6480464 bifenthrin binds to BRCA1 protein CTD PMID:32278787 biphenyl-4-amine decreases expression ISO RGD:69132 6480464 4-biphenylamine results in decreased expression of BRCA1 mRNA CTD PMID:24857880 , PMID:32905825 biphenyl-4-amine multiple interactions ISO RGD:69132 6480464 TP53 protein inhibits the reaction [4-biphenylamine results in decreased expression of BRCA1 mRNA] CTD PMID:32905825 bis(2-chloroethyl) sulfide decreases expression ISO RGD:69132 6480464 Mustard Gas results in decreased expression of BRCA1 mRNA CTD PMID:33491125 bisphenol A increases methylation ISO RGD:69132 6480464 bisphenol A results in increased methylation of BRCA1 gene CTD PMID:22258036 bisphenol A increases methylation ISO RGD:10246 6480464 bisphenol A results in increased methylation of BRCA1 promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of BRCA1 mRNA CTD PMID:27208089 , PMID:32145629 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of BRCA1 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:69132 6480464 bisphenol A results in increased expression of BRCA1 mRNA, bisphenol A results in increased expression of BRCA1 protein CTD PMID:22576693 , PMID:25933419 bisphenol A increases response to substance ISO RGD:10246 6480464 BRCA1 gene mutant form results in increased susceptibility to bisphenol A CTD PMID:20868731 bisphenol A affects response to substance ISO RGD:69132 6480464 BRCA1 protein affects the susceptibility to bisphenol A CTD PMID:20868731 bisphenol A multiple interactions ISO RGD:69132 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of BRCA1 gene more ... CTD PMID:20868731 more ... bisphenol A decreases expression ISO RGD:69132 6480464 bisphenol A results in decreased expression of BRCA1 mRNA CTD PMID:16029874 bortezomib decreases expression ISO RGD:69132 6480464 Bortezomib results in decreased expression of BRCA1 mRNA CTD PMID:21917757 bortezomib multiple interactions ISO RGD:10246 6480464 BRCA1 protein inhibits the reaction [BRCA1 gene mutant form results in increased susceptibility to Bortezomib] CTD PMID:25522274 bortezomib increases response to substance ISO RGD:10246 6480464 BRCA1 gene mutant form results in increased susceptibility to Bortezomib CTD PMID:25522274 bortezomib multiple interactions ISO RGD:69132 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in decreased expression of AKR7A2 mRNA more ... CTD PMID:25522274 bortezomib decreases ubiquitination ISO RGD:69132 6480464 Bortezomib results in decreased ubiquitination of BRCA1 protein CTD PMID:21917757 bortezomib increases response to substance ISO RGD:69132 6480464 BRCA1 mutant form results in increased susceptibility to Bortezomib CTD PMID:25522274 bromoacetate decreases expression ISO RGD:69132 6480464 bromoacetate results in decreased expression of BRCA1 mRNA CTD PMID:19753638 cadmium atom decreases expression ISO RGD:69132 6480464 Cadmium results in decreased expression of BRCA1 mRNA, Cadmium results in decreased expression of BRCA1 protein CTD PMID:20049202 , PMID:31646340 cadmium dichloride decreases expression ISO RGD:69132 6480464 Cadmium Chloride results in decreased expression of BRCA1 mRNA CTD PMID:26525392 caffeine affects phosphorylation ISO RGD:69132 6480464 Caffeine affects the phosphorylation of BRCA1 protein CTD PMID:35688186 calcitriol multiple interactions ISO RGD:69132 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of BRCA1 mRNA more ... CTD PMID:21592394 calcitriol decreases expression ISO RGD:69132 6480464 Calcitriol results in decreased expression of BRCA1 mRNA CTD PMID:21592394 Calcium propionate affects response to substance ISO RGD:69132 6480464 BRCA1 exon mutant form affects the susceptibility to calcium propionate CTD PMID:31333813 camptothecin decreases response to substance ISO RGD:69132 6480464 BRCA1 mRNA results in decreased susceptibility to Camptothecin CTD PMID:25269479 camptothecin decreases expression ISO RGD:69132 6480464 Camptothecin results in decreased expression of BRCA1 mRNA CTD PMID:10344722 cannabidiol decreases expression ISO RGD:69132 6480464 Cannabidiol results in decreased expression of BRCA1 mRNA CTD PMID:33244087 , PMID:36519830 cannabidiol multiple interactions ISO RGD:69132 6480464 [Cannabidiol co-treated with moringin] results in increased expression of BRCA1 mRNA CTD PMID:30096889 cannabidiol increases expression ISO RGD:69132 6480464 Cannabidiol results in increased expression of BRCA1 mRNA CTD PMID:27918106 carboplatin decreases activity ISO RGD:69132 6480464 Carboplatin results in decreased activity of BRCA1 protein CTD PMID:20878461 carfilzomib increases response to substance ISO RGD:69132 6480464 BRCA1 mutant form results in increased susceptibility to carfilzomib CTD PMID:25522274 casticin increases expression ISO RGD:69132 6480464 casticin results in increased expression of BRCA1 protein CTD PMID:29098808 ceric oxide decreases expression EXP 6480464 ceric oxide results in decreased expression of BRCA1 mRNA CTD PMID:29463257 CGP 52608 multiple interactions ISO RGD:69132 6480464 CGP 52608 promotes the reaction [RORA protein binds to BRCA1 gene] CTD PMID:28238834 chlorpyrifos decreases expression ISO RGD:10246 6480464 Chlorpyrifos results in decreased expression of BRCA1 mRNA CTD PMID:37019170 choline multiple interactions ISO RGD:10246 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BRCA1 mRNA CTD PMID:20938992 cisplatin multiple interactions ISO RGD:69132 6480464 [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of BRCA1 mRNA more ... CTD PMID:20623183 more ... cisplatin increases expression ISO RGD:69132 6480464 Cisplatin results in increased expression of BRCA1 mRNA, Cisplatin results in increased expression of BRCA1 protein CTD PMID:20623183 , PMID:27594783 cisplatin decreases response to substance ISO RGD:69132 6480464 BRCA1 protein results in decreased susceptibility to Cisplatin, BRCA1 results in decreased susceptibility to Cisplatin CTD PMID:20603439 more ... cisplatin increases phosphorylation ISO RGD:10246 6480464 Cisplatin results in increased phosphorylation of BRCA1 protein CTD PMID:22006019 cisplatin increases expression ISO RGD:10246 6480464 Cisplatin results in increased expression of BRCA1 mRNA CTD PMID:21151649 cisplatin decreases response to substance ISO RGD:10246 6480464 BRCA1 results in decreased susceptibility to Cisplatin CTD PMID:21771338 cisplatin decreases activity ISO RGD:69132 6480464 Cisplatin results in decreased activity of BRCA1 protein CTD PMID:20878461 cobalt dichloride decreases expression ISO RGD:69132 6480464 cobaltous chloride results in decreased expression of BRCA1 mRNA CTD PMID:19376846 copper atom multiple interactions ISO RGD:69132 6480464 [Chelating Agents binds to Copper] which results in increased expression of BRCA1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:69132 6480464 [Chelating Agents binds to Copper] which results in increased expression of BRCA1 mRNA CTD PMID:30911355 copper(II) sulfate affects expression ISO RGD:69132 6480464 Copper Sulfate affects the expression of BRCA1 mRNA CTD PMID:19549813 coumarin affects phosphorylation ISO RGD:69132 6480464 coumarin affects the phosphorylation of BRCA1 protein CTD PMID:35688186 coumestrol multiple interactions ISO RGD:69132 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 coumestrol increases expression ISO RGD:69132 6480464 Coumestrol results in increased expression of BRCA1 mRNA CTD PMID:19167446 crocidolite asbestos affects expression ISO RGD:69132 6480464 Asbestos, Crocidolite affects the expression of BRCA1 mRNA CTD PMID:17331233 cycloheximide multiple interactions ISO RGD:69132 6480464 Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA] CTD PMID:10344722 cycloheximide multiple interactions ISO RGD:10246 6480464 Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] CTD PMID:29576526 cyclosporin A decreases expression ISO RGD:10246 6480464 Cyclosporine results in decreased expression of BRCA1 mRNA CTD PMID:17942131 , PMID:19770486 cyclosporin A decreases expression ISO RGD:69132 6480464 Cyclosporine results in decreased expression of BRCA1 mRNA CTD PMID:21632981 , PMID:25562108 cyhalothrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of BRCA1 protein CTD PMID:34896426 cypermethrin decreases expression ISO RGD:69132 6480464 cypermethrin results in decreased expression of BRCA1 protein CTD PMID:36063984 cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of BRCA1 protein CTD PMID:34896426 daidzein increases expression ISO RGD:69132 6480464 daidzein results in increased expression of BRCA1 mRNA CTD PMID:17266178 DDE increases expression ISO RGD:69132 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of BRCA1 mRNA CTD PMID:20206645 DDE multiple interactions ISO RGD:69132 6480464 fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BRCA1 mRNA] CTD PMID:20206645 Decamethylcyclopentasiloxane decreases expression ISO RGD:69132 6480464 decamethylcyclopentasiloxane results in decreased expression of BRCA1 protein CTD PMID:27601420 Decamethylcyclopentasiloxane affects expression ISO RGD:69132 6480464 decamethylcyclopentasiloxane affects the expression of BRCA1 mRNA CTD PMID:27601420 deguelin decreases expression ISO RGD:69132 6480464 deguelin results in decreased expression of BRCA1 mRNA CTD PMID:22227970 diamminedichloroplatinum decreases activity ISO RGD:69132 6480464 transplatin results in decreased activity of BRCA1 protein CTD PMID:20878461 diarsenic trioxide increases expression ISO RGD:69132 6480464 Arsenic Trioxide results in increased expression of BRCA1 mRNA CTD PMID:20458559 dibenzofuran decreases expression EXP 6480464 dibenzofuran analog results in decreased expression of BRCA1 mRNA CTD PMID:20566336 dibutyl phthalate decreases expression ISO RGD:10246 6480464 Dibutyl Phthalate results in decreased expression of BRCA1 mRNA, Dibutyl Phthalate results in decreased expression of BRCA1 protein CTD PMID:21266533 , PMID:31318015 diclofenac increases expression ISO RGD:10246 6480464 Diclofenac results in increased expression of BRCA1 mRNA CTD PMID:26934552 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of BRCA1 mRNA CTD PMID:22546817 dioxygen decreases expression ISO RGD:69132 6480464 Oxygen deficiency results in decreased expression of BRCA1 mRNA, Oxygen deficiency results in decreased expression of BRCA1 protein CTD PMID:17599377 more ... disodium selenite decreases expression ISO RGD:69132 6480464 Sodium Selenite results in decreased expression of BRCA1 mRNA CTD PMID:10344722 doxorubicin decreases expression ISO RGD:69132 6480464 Doxorubicin results in decreased expression of BRCA1 mRNA CTD PMID:10344722 more ... doxorubicin multiple interactions ISO RGD:69132 6480464 Doxorubicin inhibits the reaction [[RBBP8 protein binds to BRCA1 protein binds to E2F1 protein] which results in increased expression of ATM mRNA], Doxorubicin inhibits the reaction [BRCA1 protein binds to ATM promoter] CTD PMID:22832221 emetine multiple interactions ISO RGD:10246 6480464 Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] CTD PMID:29576526 endosulfan affects expression ISO RGD:69132 6480464 Endosulfan affects the expression of BRCA1 mRNA CTD PMID:29705383 endosulfan multiple interactions ISO RGD:69132 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Endosulfan affects the expression of BRCA1 mRNA] CTD PMID:29705383 Enterolactone multiple interactions ISO RGD:69132 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BRCA1 mRNA CTD PMID:19167446 erlotinib hydrochloride multiple interactions ISO RGD:69132 6480464 [Erlotinib Hydrochloride results in decreased activity of EGFR protein] which results in decreased phosphorylation of BRCA1 protein CTD PMID:23548265 ethanol multiple interactions ISO RGD:10246 6480464 [BRCA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine more ... CTD PMID:26629949 ethanol increases response to substance ISO RGD:10246 6480464 BRCA1 gene mutant form results in increased susceptibility to Ethanol CTD PMID:26629949 etoposide multiple interactions ISO RGD:69132 6480464 BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein] more ... CTD PMID:16417649 , PMID:26259609 etoposide increases expression ISO RGD:69132 6480464 Etoposide results in increased expression of BRCA1 protein CTD PMID:26259609 etoposide decreases expression ISO RGD:69132 6480464 Etoposide results in decreased expression of BRCA1 mRNA CTD PMID:15607317 fenthion decreases expression ISO RGD:69132 6480464 Fenthion results in decreased expression of BRCA1 mRNA CTD PMID:33221015 fenvalerate affects binding ISO RGD:69132 6480464 fenvalerate binds to BRCA1 protein CTD PMID:32278787 fenvalerate multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of BRCA1 protein CTD PMID:34896426 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of BRCA1 mRNA CTD PMID:30307764 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of BRCA1 mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:10246 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BRCA1 mRNA CTD PMID:20938992 folic acid multiple interactions ISO RGD:69132 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of BRCA1 mRNA CTD PMID:24657277 fulvestrant decreases expression ISO RGD:69132 6480464 Fulvestrant results in decreased expression of BRCA1 mRNA CTD PMID:20206645 , PMID:31646340 fulvestrant multiple interactions ISO RGD:69132 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in increased methylation of BRCA1 gene more ... CTD PMID:12473173 more ... furan increases expression EXP 6480464 furan results in increased expression of BRCA1 mRNA CTD PMID:22079235 furan decreases expression EXP 6480464 furan results in decreased expression of BRCA1 mRNA CTD PMID:25539665 gemcitabine decreases response to substance ISO RGD:10246 6480464 BRCA1 results in decreased susceptibility to Gemcitabine CTD PMID:21771338 gemcitabine increases expression ISO RGD:69132 6480464 Gemcitabine results in increased expression of BRCA1 mRNA CTD PMID:20103597 genistein multiple interactions ISO RGD:69132 6480464 [indole-3-carbinol co-treated with Genistein] results in increased expression of BRCA1 protein, Genistein inhibits the reaction [sodium arsenite inhibits the reaction [Estradiol results in increased expression of BRCA1 protein]] CTD PMID:16434996 , PMID:30664189 genistein increases expression ISO RGD:69132 6480464 Genistein results in increased expression of BRCA1 mRNA, Genistein results in increased expression of BRCA1 protein CTD PMID:16434996 , PMID:17266178 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of BRCA1 mRNA CTD PMID:33387578 geraniol decreases expression ISO RGD:69132 6480464 geraniol results in decreased expression of BRCA1 mRNA CTD PMID:27683099 glyphosate decreases expression ISO RGD:69132 6480464 glyphosate results in decreased expression of BRCA1 mRNA CTD PMID:31295307 gold atom multiple interactions ISO RGD:69132 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of BRCA1 mRNA CTD PMID:28433809 gold atom decreases expression ISO RGD:69132 6480464 Gold analog results in decreased expression of BRCA1 mRNA CTD PMID:36057382 gold(0) multiple interactions ISO RGD:69132 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of BRCA1 mRNA CTD PMID:28433809 gold(0) decreases expression ISO RGD:69132 6480464 Gold analog results in decreased expression of BRCA1 mRNA CTD PMID:36057382 hexamethylcyclotrisiloxane affects expression ISO RGD:69132 6480464 hexamethylcyclotrisiloxane affects the expression of BRCA1 mRNA CTD PMID:27601420 hexamethylcyclotrisiloxane decreases expression ISO RGD:69132 6480464 hexamethylcyclotrisiloxane results in decreased expression of BRCA1 protein CTD PMID:27601420 hydrogen peroxide decreases response to substance ISO RGD:69132 6480464 BRCA1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:15520196 hydrogen peroxide multiple interactions ISO RGD:10246 6480464 N-(oxo-5 more ... CTD PMID:31494107 hydrogen peroxide increases expression ISO RGD:69132 6480464 Hydrogen Peroxide results in increased expression of BRCA1 mRNA CTD PMID:22539617 hydroquinone increases expression ISO RGD:69132 6480464 hydroquinone results in increased expression of BRCA1 protein CTD PMID:29421518 indole-3-methanol multiple interactions ISO RGD:69132 6480464 [indole-3-carbinol co-treated with Genistein] results in increased expression of BRCA1 protein more ... CTD PMID:11110848 more ... indole-3-methanol increases expression ISO RGD:69132 6480464 indole-3-carbinol results in increased expression of BRCA1 mRNA, indole-3-carbinol results in increased expression of BRCA1 protein CTD PMID:11110848 , PMID:16434996 L-methionine multiple interactions ISO RGD:10246 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BRCA1 mRNA CTD PMID:20938992 Lasiocarpine multiple interactions ISO RGD:69132 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRCA1 mRNA CTD PMID:33884520 Lasiocarpine increases expression ISO RGD:69132 6480464 lasiocarpine results in increased expression of BRCA1 mRNA CTD PMID:32234424 lead diacetate decreases expression ISO RGD:10246 6480464 lead acetate results in decreased expression of BRCA1 mRNA CTD PMID:22613225 leptomycin B decreases expression ISO RGD:69132 6480464 leptomycin B results in decreased expression of BRCA1 mRNA CTD PMID:20803015 leptomycin B multiple interactions ISO RGD:69132 6480464 [leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of BRCA1 mRNA CTD PMID:20803015 lucanthone decreases expression ISO RGD:69132 6480464 Lucanthone results in decreased expression of BRCA1 mRNA CTD PMID:21148553 methotrexate multiple interactions ISO RGD:69132 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of BRCA1 mRNA, BRCA1 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Methotrexate] CTD PMID:21875941 , PMID:24657277 methotrexate increases expression ISO RGD:69132 6480464 Methotrexate results in increased expression of BRCA1 mRNA CTD PMID:21678067 methoxsalen multiple interactions ISO RGD:69132 6480464 Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of BRCA1 protein modified form] CTD PMID:23907605 methyl methanesulfonate increases expression ISO RGD:69132 6480464 Methyl Methanesulfonate results in increased expression of BRCA1 mRNA CTD PMID:23649840 mitomycin C increases response to substance ISO RGD:69132 6480464 BRCA1 protein mutant form results in increased susceptibility to Mitomycin CTD PMID:26320175 Monobutylphthalate affects expression EXP 6480464 monobutyl phthalate affects the expression of BRCA1 mRNA CTD PMID:20864626 myristicin decreases expression ISO RGD:69132 6480464 myristicin results in decreased expression of BRCA1 mRNA CTD PMID:24792648 N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO RGD:69132 6480464 Methylnitronitrosoguanidine results in increased expression of BRCA1 mRNA CTD PMID:12634122 N-nitrosodiethylamine increases expression ISO RGD:10246 6480464 Diethylnitrosamine results in increased expression of BRCA1 mRNA CTD PMID:17854601 N-nitrosodiethylamine multiple interactions ISO RGD:10246 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BRCA1 mRNA] CTD PMID:17854601 nickel dichloride decreases expression ISO RGD:69132 6480464 nickel chloride results in decreased expression of BRCA1 mRNA, nickel chloride results in decreased expression of BRCA1 protein CTD PMID:28472268 nicotine decreases expression ISO RGD:69132 6480464 Nicotine results in decreased expression of BRCA1 mRNA CTD PMID:18247414 nicotine multiple interactions ISO RGD:69132 6480464 Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of BRCA1 protein modified form] CTD PMID:23907605 nitrogen mustard decreases expression ISO RGD:69132 6480464 Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA CTD PMID:10344722 nitrogen mustard multiple interactions ISO RGD:69132 6480464 Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA] CTD PMID:10344722 O-methyleugenol decreases expression EXP 6480464 methyleugenol results in decreased expression of BRCA1 mRNA CTD PMID:21659616 , PMID:26011634 octamethylcyclotetrasiloxane decreases expression ISO RGD:69132 6480464 octamethylcyclotetrasiloxane results in decreased expression of BRCA1 protein CTD PMID:27601420 octamethylcyclotetrasiloxane affects expression ISO RGD:69132 6480464 octamethylcyclotetrasiloxane affects the expression of BRCA1 mRNA CTD PMID:27601420 olaparib affects response to substance ISO RGD:69132 6480464 BRCA1 affects the susceptibility to olaparib CTD PMID:21633166 ouabain decreases expression ISO RGD:69132 6480464 Ouabain results in decreased expression of BRCA1 protein CTD PMID:31436044 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of BRCA1 mRNA CTD PMID:25729387 oxaliplatin decreases activity ISO RGD:69132 6480464 oxaliplatin results in decreased activity of BRCA1 protein CTD PMID:20878461 oxybenzone increases expression ISO RGD:69132 6480464 oxybenzone results in increased expression of BRCA1 mRNA CTD PMID:36581016 ozone decreases expression ISO RGD:10246 6480464 Ozone results in decreased expression of BRCA1 mRNA CTD PMID:24336422 ozone increases expression ISO RGD:69132 6480464 Ozone results in increased expression of BRCA1 mRNA CTD PMID:23033980 ozone multiple interactions ISO RGD:69132 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of BRCA1 mRNA more ... CTD PMID:32699268 ozone multiple interactions ISO RGD:10246 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of BRCA1 mRNA more ... CTD PMID:25658374 more ... paclitaxel decreases expression ISO RGD:69132 6480464 Paclitaxel results in decreased expression of BRCA1 mRNA CTD PMID:15607317 paracetamol affects expression ISO RGD:10246 6480464 Acetaminophen affects the expression of BRCA1 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of BRCA1 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:10246 6480464 Acetaminophen results in increased expression of BRCA1 protein CTD PMID:29540258 paracetamol increases activity EXP 6480464 Acetaminophen results in increased activity of BRCA1 protein CTD PMID:25858767 paracetamol increases expression ISO RGD:69132 6480464 Acetaminophen results in increased expression of BRCA1 mRNA CTD PMID:22230336 paracetamol decreases expression ISO RGD:10246 6480464 Acetaminophen results in decreased expression of BRCA1 mRNA CTD PMID:17942131 paraquat decreases response to substance ISO RGD:69132 6480464 BRCA1 protein results in decreased susceptibility to Paraquat CTD PMID:15520196 paraquat multiple interactions ISO RGD:10246 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BRCA1 mRNA CTD PMID:28012437 PCB138 multiple interactions ISO RGD:69132 6480464 2 more ... CTD PMID:12473173 phenobarbital affects expression ISO RGD:69132 6480464 Phenobarbital affects the expression of BRCA1 mRNA CTD PMID:19159669 phenobarbital affects expression ISO RGD:10246 6480464 Phenobarbital affects the expression of BRCA1 mRNA CTD PMID:23091169 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased expression of BRCA1 protein CTD PMID:12203372 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10246 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BRCA1 mRNA CTD PMID:16368122 phosphoramide mustard affects expression EXP 6480464 phosphoramide mustard affects the expression of BRCA1 mRNA CTD PMID:25497287 phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of BRCA1 mRNA, phosphoramide mustard results in increased expression of BRCA1 protein CTD PMID:25497287 , PMID:26708502 pirinixic acid multiple interactions ISO RGD:10246 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of BRCA1 mRNA] CTD PMID:17950772 pirinixic acid decreases expression ISO RGD:10246 6480464 pirinixic acid results in decreased expression of BRCA1 mRNA CTD PMID:23811191 pirinixic acid increases expression ISO RGD:10246 6480464 pirinixic acid results in increased expression of BRCA1 mRNA CTD PMID:17950772 potassium bromate increases expression ISO RGD:69132 6480464 potassium bromate results in increased expression of BRCA1 mRNA CTD PMID:22539617 potassium chromate decreases expression ISO RGD:69132 6480464 potassium chromate(VI) results in decreased expression of BRCA1 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:69132 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of BRCA1 mRNA CTD PMID:22079256 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:10246 6480464 [1 more ... CTD PMID:23626729 procyanidin B2 increases expression ISO RGD:69132 6480464 procyanidin B2 results in increased expression of BRCA1 mRNA CTD PMID:25839702 promethazine decreases expression EXP 6480464 Promethazine results in decreased expression of BRCA1 mRNA CTD PMID:26011634 propanal decreases expression ISO RGD:69132 6480464 propionaldehyde results in decreased expression of BRCA1 mRNA CTD PMID:26079696 pyrethrins decreases expression EXP 6480464 Pyrethrins results in decreased expression of BRCA1 protein CTD PMID:34896426 quercetin increases expression ISO RGD:69132 6480464 Quercetin results in increased expression of BRCA1 mRNA CTD PMID:14715546 , PMID:21632981 reactive oxygen species multiple interactions ISO RGD:69132 6480464 BRCA1 inhibits the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species], NFE2L2 protein inhibits the reaction [BRCA1 inhibits the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species]] CTD PMID:22192953 resveratrol increases expression ISO RGD:69132 6480464 resveratrol results in increased expression of BRCA1 mRNA, resveratrol results in increased expression of BRCA1 protein CTD PMID:15149879 , PMID:25533949 resveratrol decreases expression EXP 6480464 Resveratrol results in decreased expression of BRCA1 mRNA CTD PMID:33775663 resveratrol affects localization ISO RGD:69132 6480464 resveratrol affects the localization of BRCA1 protein CTD PMID:19559722 resveratrol multiple interactions ISO RGD:69132 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of BRCA1 mRNA more ... CTD PMID:19167446 more ... resveratrol increases expression EXP 6480464 resveratrol results in increased expression of BRCA1 mRNA, resveratrol results in increased expression of BRCA1 protein CTD PMID:24136580 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter]] more ... CTD PMID:24136580 riddelliine multiple interactions ISO RGD:69132 6480464 [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA1 mRNA CTD PMID:33884520 rotenone increases expression ISO RGD:69132 6480464 Rotenone results in increased expression of BRCA1 mRNA CTD PMID:18191903 silicon dioxide increases expression ISO RGD:10246 6480464 Silicon Dioxide results in increased expression of BRCA1 mRNA CTD PMID:29341224 sodium arsenite affects expression ISO RGD:10246 6480464 sodium arsenite affects the expression of BRCA1 mRNA CTD PMID:16507464 sodium arsenite increases methylation ISO RGD:69132 6480464 sodium arsenite results in increased methylation of BRCA1 gene CTD PMID:30664189 sodium arsenite decreases expression ISO RGD:69132 6480464 sodium arsenite results in decreased expression of BRCA1 mRNA, sodium arsenite results in decreased expression of BRCA1 protein CTD PMID:30664189 sodium arsenite multiple interactions ISO RGD:69132 6480464 Genistein inhibits the reaction [sodium arsenite inhibits the reaction [Estradiol results in increased expression of BRCA1 protein]] more ... CTD PMID:30664189 sodium arsenite multiple interactions ISO RGD:10246 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BRCA1 mRNA CTD PMID:16368122 sodium arsenite increases expression ISO RGD:69132 6480464 sodium arsenite results in increased expression of BRCA1 mRNA CTD PMID:12760830 , PMID:29301061 sodium dichromate increases expression ISO RGD:10246 6480464 sodium bichromate results in increased expression of BRCA1 mRNA CTD PMID:22155349 succimer multiple interactions ISO RGD:10246 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of BRCA1 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of BRCA1 mRNA CTD PMID:21641980 , PMID:26378955 sulindac decreases expression ISO RGD:69132 6480464 Sulindac results in decreased expression of BRCA1 mRNA CTD PMID:16273229 tamibarotene decreases expression ISO RGD:69132 6480464 tamibarotene results in decreased expression of BRCA1 mRNA CTD PMID:15498508 tamoxifen affects activity ISO RGD:69132 6480464 BRCA1 affects the activity of Tamoxifen CTD PMID:15750629 tamoxifen multiple interactions ISO RGD:10246 6480464 [Tamoxifen co-treated with BRCA1 protein mutant form] results in decreased expression of ESR1 protein CTD PMID:15750629 tamoxifen increases response to substance ISO RGD:69132 6480464 BRCA1 protein results in increased susceptibility to Tamoxifen CTD PMID:18997820 tamoxifen multiple interactions ISO RGD:69132 6480464 [Tamoxifen co-treated with Estradiol] results in increased expression of BRCA1 protein more ... CTD PMID:18997820 , PMID:30664189 terbufos decreases expression ISO RGD:69132 6480464 terbufos results in decreased expression of BRCA1 mRNA CTD PMID:33221015 testosterone multiple interactions ISO RGD:69132 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of BRCA1 mRNA more ... CTD PMID:21592394 testosterone decreases expression ISO RGD:69132 6480464 Testosterone results in decreased expression of BRCA1 mRNA CTD PMID:21592394 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of BRCA1 mRNA CTD PMID:12734012 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BRCA1 mRNA] CTD PMID:31150632 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of BRCA1 mRNA CTD PMID:31150632 tetrachloromethane increases expression ISO RGD:10246 6480464 Carbon Tetrachloride results in increased expression of BRCA1 mRNA CTD PMID:17484886 tetramethrin affects binding ISO RGD:69132 6480464 tetramethrin binds to BRCA1 protein CTD PMID:32278787 thapsigargin increases expression ISO RGD:69132 6480464 Thapsigargin results in increased expression of BRCA1 mRNA, Thapsigargin results in increased expression of BRCA1 protein CTD PMID:16434996 thapsigargin affects localization ISO RGD:10246 6480464 Thapsigargin affects the localization of BRCA1 mRNA CTD PMID:29576526 thapsigargin multiple interactions ISO RGD:10246 6480464 Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA], Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] CTD PMID:29576526 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of BRCA1 mRNA CTD PMID:26011634 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of BRCA1 mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of BRCA1 mRNA CTD PMID:25729387 toxaphene increases expression ISO RGD:69132 6480464 Toxaphene results in increased expression of BRCA1 mRNA CTD PMID:12473173 transplatin decreases activity ISO RGD:69132 6480464 transplatin results in decreased activity of BRCA1 protein CTD PMID:20878461 Tributyltin oxide decreases expression ISO RGD:10246 6480464 bis(tri-n-butyltin)oxide results in decreased expression of BRCA1 mRNA CTD PMID:17942131 trichostatin A decreases expression ISO RGD:69132 6480464 trichostatin A results in decreased expression of BRCA1 mRNA CTD PMID:23770000 triclosan decreases expression ISO RGD:69132 6480464 Triclosan results in decreased expression of BRCA1 mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:10246 6480464 trimellitic anhydride results in increased expression of BRCA1 mRNA CTD PMID:19042947 troglitazone decreases expression ISO RGD:69132 6480464 troglitazone results in decreased expression of BRCA1 mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO RGD:10246 6480464 trovafloxacin results in decreased expression of BRCA1 mRNA CTD PMID:35537566 tungsten decreases expression ISO RGD:10246 6480464 Tungsten results in decreased expression of BRCA1 mRNA CTD PMID:30912803 tunicamycin increases expression ISO RGD:69132 6480464 Tunicamycin results in increased expression of BRCA1 protein CTD PMID:16434996 urethane decreases expression ISO RGD:69132 6480464 Urethane results in decreased expression of BRCA1 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:69132 6480464 Valproic Acid results in decreased expression of BRCA1 mRNA CTD PMID:20585447 , PMID:28001369 valproic acid decreases expression ISO RGD:10246 6480464 Valproic Acid results in decreased expression of BRCA1 mRNA CTD PMID:24913804 valproic acid increases expression ISO RGD:10246 6480464 Valproic Acid results in increased expression of BRCA1 mRNA CTD PMID:24913804 valproic acid increases methylation ISO RGD:69132 6480464 Valproic Acid results in increased methylation of BRCA1 gene CTD PMID:29154799 veliparib affects response to substance ISO RGD:69132 6480464 BRCA1 affects the susceptibility to veliparib CTD PMID:21633166 veliparib decreases response to substance ISO RGD:69132 6480464 BRCA1 protein results in decreased susceptibility to veliparib CTD PMID:21707865 vorinostat multiple interactions ISO RGD:69132 6480464 vorinostat inhibits the reaction [BRCA1 results in decreased susceptibility to Cisplatin] CTD PMID:21854619 vorinostat decreases expression ISO RGD:69132 6480464 vorinostat results in decreased expression of BRCA1 protein CTD PMID:21854619 zearalenone increases expression ISO RGD:10246 6480464 Zearalenone results in increased expression of BRCA1 mRNA CTD PMID:28552778 zearalenone increases expression ISO RGD:69132 6480464 Zearalenone results in increased expression of BRCA1 mRNA CTD PMID:28965971
