Bgn (biglycan) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Bgn (biglycan) Rattus norvegicus
Analyze
Symbol: Bgn
Name: biglycan
RGD ID: 2207
Description: Predicted to enable cytokine binding activity; extracellular matrix binding activity; and glycosaminoglycan binding activity. Involved in blood vessel remodeling. Predicted to be located in several cellular components, including cell surface; sarcolemma; and transport vesicle. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Meester-Loeys syndrome and X-linked spondyloepimetaphyseal dysplasia. Orthologous to human BGN (biglycan); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: bone/cartilage proteclycan 1; bone/cartilage proteclycan 1 precursor; bone/cartilage proteoglycan I; BSPG1; PG-S1; small proteoglycan I (biglycan); Small proteoglycan I (biglycan) bone (BSPG1) (bone/cartilage proteclycan 1 precursor); Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,348,633 - 156,360,797 (+)NCBIGRCr8
mRatBN7.2X151,197,296 - 151,209,458 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,197,273 - 151,209,461 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX153,338,436 - 153,350,608 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,901,667 - 156,913,844 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,573,498 - 154,585,670 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,319,042 - 157,331,204 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,319,046 - 157,331,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01153,067,990 - 153,080,152 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,380,557 - 159,393,409 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X159,453,989 - 159,466,841 (+)NCBI
Celera1136,680,181 - 136,692,331 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
aluminium atom  (ISO)
aluminium oxide  (ISO)
aluminium(0)  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-D-glucosamine  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium silicate  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chromium atom  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
DDT  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazepam  (ISO)
diazinon  (ISO)
dioxygen  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
erastin  (ISO)
ethanol  (ISO)
fentanyl  (EXP)
flutamide  (EXP)
folpet  (ISO)
furan  (EXP)
glutathione  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
malonaldehyde  (ISO)
Mesaconitine  (EXP)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
niclosamide  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl caffeate  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP,ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
Soman  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Increased expression of biglycan mRNA in pressure-overloaded rat heart. Ayada Y, etal., Clin Exp Hypertens 2001 Nov;23(8):633-43.
2. Vascular smooth muscle biglycan represents a highly conserved proteoglycan within the arterial wall. Dreher KL, etal., Eur J Cell Biol 1990 Dec;53(2):296-304.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Identification and Analysis of Key Genes Driving Gastric Cancer Through Bioinformatics. Liu Z, etal., Genet Test Mol Biomarkers. 2021 Jan;25(1):1-11. doi: 10.1089/gtmb.2020.0126.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:2212616   PMID:12719420   PMID:15489334   PMID:16810681   PMID:18757743   PMID:19056867   PMID:19701788   PMID:19932218   PMID:20551380   PMID:22206666   PMID:23376485   PMID:23504199  
PMID:23533145   PMID:23900597   PMID:24006456   PMID:25931508   PMID:26316108   PMID:27068509   PMID:27559042   PMID:30361391  


Genomics

Comparative Map Data
Bgn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,348,633 - 156,360,797 (+)NCBIGRCr8
mRatBN7.2X151,197,296 - 151,209,458 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,197,273 - 151,209,461 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX153,338,436 - 153,350,608 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,901,667 - 156,913,844 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,573,498 - 154,585,670 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,319,042 - 157,331,204 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,319,046 - 157,331,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01153,067,990 - 153,080,152 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,380,557 - 159,393,409 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X159,453,989 - 159,466,841 (+)NCBI
Celera1136,680,181 - 136,692,331 (-)NCBICelera
Cytogenetic MapXq37NCBI
BGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,494,980 - 153,509,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX153,494,980 - 153,509,546 (+)EnsemblGRCh38hg38GRCh38
GRCh37X152,760,438 - 152,775,004 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,413,605 - 152,428,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X152,281,257 - 152,295,851NCBI
CeleraX152,994,048 - 153,008,701 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX141,428,414 - 141,433,357 (+)NCBIHuRef
CHM1_1X152,634,856 - 152,649,511 (+)NCBICHM1_1
T2T-CHM13v2.0X151,768,553 - 151,783,109 (+)NCBIT2T-CHM13v2.0
Bgn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,527,207 - 72,539,542 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,527,208 - 72,539,539 (+)EnsemblGRCm39 Ensembl
GRCm38X73,483,601 - 73,495,936 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,483,602 - 73,495,933 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X70,728,974 - 70,741,275 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X69,736,364 - 69,748,651 (+)NCBIMGSCv36mm8
CeleraX64,737,508 - 64,749,795 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.33NCBI
Bgn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580252,139 - 263,663 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955580252,183 - 263,179 (+)NCBIChiLan1.0ChiLan1.0
BGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X153,534,986 - 153,549,745 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X153,538,710 - 153,553,349 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,045,298 - 143,059,892 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X152,931,608 - 152,946,292 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX152,931,608 - 152,946,292 (+)Ensemblpanpan1.1panPan2
BGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X121,330,371 - 121,334,634 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX121,330,259 - 121,334,634 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX106,652,078 - 106,665,354 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X124,463,956 - 124,477,899 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX124,463,911 - 124,477,891 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X120,233,690 - 120,246,965 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X122,748,802 - 122,762,079 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,510,823 - 122,524,101 (+)NCBIUU_Cfam_GSD_1.0
Bgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X118,637,802 - 118,651,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936809375,543 - 389,756 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936809375,589 - 389,718 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,275,305 - 124,295,445 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,282,048 - 124,295,450 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,845,604 - 141,858,856 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X127,926,018 - 127,940,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX127,926,009 - 127,941,164 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606565,787,635 - 65,802,224 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bgn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946230,519 - 241,850 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946230,529 - 241,448 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bgn
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:163
Count of miRNA genes:120
Interacting mature miRNAs:140
Transcripts:ENSRNOT00000023920
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000085201   ⟹   ENSRNOP00000072449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,197,273 - 151,209,456 (+)Ensembl
Rnor_6.0 EnsemblX157,319,046 - 157,331,204 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098825   ⟹   ENSRNOP00000096760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,203,548 - 151,209,459 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104560   ⟹   ENSRNOP00000090168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,197,281 - 151,209,451 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119907   ⟹   ENSRNOP00000078269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,197,281 - 151,209,461 (+)Ensembl
RefSeq Acc Id: NM_017087   ⟹   NP_058783
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,348,633 - 156,360,797 (+)NCBI
mRatBN7.2X151,197,296 - 151,209,458 (+)NCBI
Rnor_6.0X157,319,042 - 157,331,204 (-)NCBI
Rnor_5.01153,067,990 - 153,080,152 (-)NCBI
RGSC_v3.4X159,380,557 - 159,393,409 (+)RGD
Celera1136,680,181 - 136,692,331 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_058783 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA58797 (Get FASTA)   NCBI Sequence Viewer  
  AAH72480 (Get FASTA)   NCBI Sequence Viewer  
  EDL85047 (Get FASTA)   NCBI Sequence Viewer  
  EDL85048 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072449.2
  ENSRNOP00000078269.1
  ENSRNOP00000090168.1
  ENSRNOP00000096760.1
GenBank Protein P47853 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058783   ⟸   NM_017087
- Peptide Label: precursor
- UniProtKB: P47853 (UniProtKB/Swiss-Prot),   A6KRY1 (UniProtKB/TrEMBL),   A0A8L2R772 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072449   ⟸   ENSRNOT00000085201
Ensembl Acc Id: ENSRNOP00000090168   ⟸   ENSRNOT00000104560
Ensembl Acc Id: ENSRNOP00000096760   ⟸   ENSRNOT00000098825
Ensembl Acc Id: ENSRNOP00000078269   ⟸   ENSRNOT00000119907
Protein Domains
LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47853-F1-model_v2 AlphaFold P47853 1-369 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702060
Promoter ID:EPDNEW_R12583
Type:initiation region
Name:Bgn_1
Description:biglycan
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X157,331,221 - 157,331,281EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2207 AgrOrtholog
BioCyc Gene G2FUF-674 BioCyc
Ensembl Genes ENSRNOG00000055962 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000085201.2 UniProtKB/TrEMBL
  ENSRNOT00000098825.1 UniProtKB/TrEMBL
  ENSRNOT00000104560.1 UniProtKB/TrEMBL
  ENSRNOT00000119907.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104041 IMAGE-MGC_LOAD
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLRP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLRP_I_decor/aspor/byglycan UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25181 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91754 IMAGE-MGC_LOAD
NCBI Gene 25181 ENTREZGENE
PANTHER AGAP008170-PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45712:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bgn PhenoGen
PIRSF SLRP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000055962 RatGTEx
SMART LRR_BAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228603
UniProt A0A8I6A8T9_RAT UniProtKB/TrEMBL
  A0A8I6AMG2_RAT UniProtKB/TrEMBL
  A0A8L2R772 ENTREZGENE, UniProtKB/TrEMBL
  A6KRY1 ENTREZGENE, UniProtKB/TrEMBL
  P47853 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2001-07-23 Bgn  biglycan      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED
2001-07-23 Bgn  Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)      Name withdrawn 67952 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in rat myocardium 631310
gene_function proteoglycan 631713
gene_homology has 88% homology to human protein 631713
gene_process may contribute to ventricular and vascular remodeling in response to pressure overload in the heart 631310
gene_regulation mRNA expression is regulated by collagen, fibronectin, and laminin 631713