Anxa5 (annexin A5) - Rat Genome Database

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Gene: Anxa5 (annexin A5) Rattus norvegicus
Analyze
Symbol: Anxa5
Name: annexin A5
RGD ID: 2120
Description: Enables several functions, including P-type calcium transporter activity; calcium-dependent phospholipid binding activity; and receptor tyrosine kinase binding activity. Involved in several processes, including cellular response to gonadotropin-releasing hormone; cellular response to lead ion; and negative regulation of prolactin secretion. Located in several cellular components, including Z disc; intercalated disc; and perikaryon. Is active in synaptic vesicle membrane. Biomarker of several diseases, including Wilson disease; cryptorchidism; glomerulonephritis; hyperthyroidism; and myocardial infarction. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: anchorin CII; annexin 5; Annexin V; annexin-5; Anx5; calphobindin I; CBP-I; CPB-I; endonexin II; LC5; lipocortin V; MGC93655; PAP-I; placental anticoagulant protein 4; placental anticoagulant protein I; PP4; thromboplastin inhibitor; VAC-alpha; vascular anticoagulant-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82121,242,133 - 121,272,935 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2121,242,136 - 121,281,400 (-)EnsemblGRCr8
mRatBN7.22119,314,007 - 119,344,703 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2119,314,007 - 119,353,369 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2125,868,632 - 125,899,139 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02123,981,142 - 124,011,637 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02118,610,122 - 118,640,625 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02123,162,477 - 123,194,730 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2123,162,461 - 123,193,130 (-)Ensemblrn6Rnor6.0
Rnor_5.02142,777,624 - 142,808,420 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42122,949,210 - 122,979,757 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2114,271,560 - 114,302,133 (-)NCBICelera
RGSC_v3.12122,894,171 - 122,924,719 (-)NCBI
RH 3.4 Map2623.7RGD
Cytogenetic Map2q25NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(Z)-3-butylidenephthalide  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
Allylamine  (EXP)
ammonium chloride  (EXP)
amphibole asbestos  (ISO)
Ampullosporin  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
atrazine  (EXP,ISO)
bacitracin  (EXP)
benzatropine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beryllium sulfate  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
buspirone  (EXP)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
Destruxin B  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP)
entinostat  (ISO)
enzyme inhibitor  (ISO)
fenthion  (ISO)
fentin chloride  (ISO)
fluoxetine  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
furfural  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glucose  (ISO)
glycidyl methacrylate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
graphite  (ISO)
griseofulvin  (ISO)
hyaluronic acid  (EXP)
hydrazine  (ISO)
hydrogen peroxide  (EXP,ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
isoflavones  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
kojic acid  (ISO)
L-ascorbic acid  (EXP,ISO)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
lithocholic acid  (ISO)
lovastatin  (ISO)
mercury dichloride  (ISO)
methidathion  (ISO)
microcystin-LR  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (ISO)
Myrtucommulone A  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
naphthalene  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
nitrates  (ISO)
nitric oxide  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
Ptaquiloside  (ISO)
quartz  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
ruthenium atom  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Sodium salicylate  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sulindac sulfide  (ISO)
T-2 toxin  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)
zearalenone  (ISO)
zinc pyrithione  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Microarray analysis of differential gene expression in lead-exposed astrocytes. Bouton CM, etal., Toxicol Appl Pharmacol. 2001 Oct 1;176(1):34-53.
2. Rat annexin V crystal structure: Ca(2+)-induced conformational changes. Concha NO, etal., Science. 1993 Sep 3;261(5126):1321-4.
3. Proteomic and tissue array profiling identifies elevated hypoxia-regulated proteins in pancreatic ductal adenocarcinoma. Cui Y, etal., Cancer Invest. 2009 Aug;27(7):747-55.
4. In vivo modulation of annexins I, II and V expression by thyroxine and methylthiouracil. el Btaouri H, etal., Eur J Biochem. 1996 Dec 15;242(3):506-11.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Immunohistochemical localization of annexin V (CaBP33) in rat organs. Giambanco I, etal., J Histochem Cytochem. 1991 Sep;39(9):1189-98.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Annexins I-VI in secretory ameloblasts and odontoblasts of rat incisor. Goldberg M, etal., J Biol Buccale. 1990 Dec;18(4):289-98.
9. A common polymorphism in the annexin V Kozak sequence (-1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients. Gonzalez-Conejero R, etal., Blood. 2002 Sep 15;100(6):2081-6.
10. Preferential localization of annexin V to the axon terminal. Gotow T, etal., Neuroscience. 1996 Nov;75(2):507-21.
11. Anti-annexin v antibodies: association with vascular involvement and disease outcome in patients with systemic sclerosis. Habeeb RA, etal., Clin Med Insights Arthritis Musculoskelet Disord. 2010 Apr 28;3:15-23.
12. Structure of rat annexin V gene and molecular diversity of its transcripts. Imai Y and Kohsaka S, Eur J Biochem 1995 Sep 1;232(2):327-34.
13. The -1C to T polymorphism in the annexin A5 gene is not associated with the risk of acute myocardial infarction or sudden cardiac death in middle-aged Finnish males. Kaikkonen KS, etal., Scand J Clin Lab Invest. 2005;65(2):133-40.
14. Measurement of plasma annexin V by ELISA in the early detection of acute myocardial infarction. Kaneko N, etal., Clin Chim Acta. 1996 Jul 15;251(1):65-80.
15. Purification of cardiac annexin V from the beagle dog heart and changes in its localization in the ischemic rat heart. Kaneko N, etal., Heart Vessels. 1994;9(3):148-54.
16. Association of annexin V with prolactin in the rat anterior pituitary gland. Kawaminami M, etal., Biochem Biophys Res Commun. 1992 Jul 31;186(2):894-8.
17. Annexin 5 inhibits thyrotropin releasing hormone (TRH) stimulated prolactin release in the primary culture of rat anterior pituitary cells. Kawaminami M, etal., Endocr J. 2004 Jun;51(3):349-54.
18. Ovariectomy enhances the expression and nuclear translocation of annexin 5 in rat anterior pituitary gonadotrophs. Kawaminami M, etal., Mol Cell Endocrinol. 1998 Jun 25;141(1-2):73-8.
19. Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage. Kirsch T, etal., Osteoarthritis Cartilage. 2000 Jul;8(4):294-302.
20. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
21. Association of neovascular age-related macular degeneration with specific gene expression patterns in peripheral white blood cells. Lederman M, etal., Invest Ophthalmol Vis Sci. 2010 Jan;51(1):53-8. Epub 2009 Aug 13.
22. Proteomic analysis of the hepatic tissue of Long-Evans Cinnamon (LEC) rats according to the natural course of Wilson disease. Lee BH, etal., Proteomics. 2011 Sep;11(18):3698-705. doi: 10.1002/pmic.201100122. Epub 2011 Aug 9.
23. Identification of a 35 kDa protein in rat spinal ganglia and sensory fibers. Li Q, etal., Neuroreport. 2004 Sep 15;15(13):2083-7.
24. Upregulation of annexins I, II, and V after traumatic spinal cord injury in adult rats. Liu N, etal., J Neurosci Res. 2004 Aug 1;77(3):391-401.
25. Presence and comparison of Ca2+ transport activity of annexins I, II, V, and VI in large unilamellar vesicles. Matsuda R, etal., Biochem Biophys Res Commun. 1997 Aug 28;237(3):499-503.
26. Localization of annexin V in rat normal kidney and experimental glomerulonephritis. Matsuda R, etal., Res Exp Med (Berl). 2001 Jan;200(2):77-92.
27. Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces. Mo Y, etal., J Biol Chem 2003 Jan 24;278(4):2437-43.
28. Myocyte apoptosis during acute myocardial infarction in rats is related to early sarcolemmal translocation of annexin A5 in border zone. Monceau V, etal., Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H965-71. Epub 2006 Feb 24.
29. Externalization of endogenous annexin A5 participates in apoptosis of rat cardiomyocytes. Monceau V, etal., Cardiovasc Res. 2004 Dec 1;64(3):496-506.
30. Pressure overload induces overexpression of annexins II and V in aortic-banded rats. Moraru II, etal., Ann N Y Acad Sci. 1998 Sep 16;853:329-32.
31. Differential expression of annexins I-VI in the rat dorsal root ganglia and spinal cord. Naciff JM, etal., J Comp Neurol. 1996 May 6;368(3):356-70.
32. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
33. Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure. Ohsawa K, etal., J Neurochem 1996 Jul;67(1):89-97.
34. Five distinct calcium and phospholipid binding proteins share homology with lipocortin I. Pepinsky RB, etal., J Biol Chem 1988 Aug 5;263(22):10799-811.
35. GOA pipeline RGD automated data pipeline
36. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
37. Purification, crystallization, and preliminary X-ray diffraction analysis of rat kidney annexin V, a calcium-dependent phospholipid-binding protein. Seaton BA, etal., J Biol Chem. 1990 Mar 15;265(8):4567-9.
38. Urinary annexin V in children with nephrotic syndrome: a new prognostic marker? Simsek B, etal., Pediatr Nephrol. 2008 Jan;23(1):79-82. Epub 2007 Nov 13.
39. Evaluation of annexin A5 as a biomarker for Alzheimer's disease and dementia with lewy bodies. Sohma H, etal., Front Aging Neurosci. 2013 Apr 5;5:15. doi: 10.3389/fnagi.2013.00015. eCollection 2013.
40. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
41. [Expression of rat annexin 5 and its effect on human sperm motility in vitro]. Tao XQ, etal., Zhonghua Nan Ke Xue. 2010 May;16(5):400-4.
42. Decreased concentration of annexin V in parkinsonian cerebrospinal fluid: speculation on the underlying cause. Vermes I, etal., Mov Disord. 1999 Nov;14(6):1008-10.
43. Annexin V is localized in association with Z-line of rat cardiac myocytes. Wang L, etal., Cardiovasc Res. 1995 Sep;30(3):363-71.
44. Lipocortin V may function as a signaling protein for vascular endothelial growth factor receptor-2/Flk-1. Wen Y, etal., Biochem Biophys Res Commun. 1999 May 19;258(3):713-21.
45. Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue. Wever KE, etal., PLoS One. 2011;6(8):e24276. doi: 10.1371/journal.pone.0024276. Epub 2011 Aug 30.
46. Investigation of annexin A5 as a biomarker for Alzheimer's disease using neuronal cell culture and mouse model. Yamaguchi M, etal., J Neurosci Res. 2010 Sep;88(12):2682-92. doi: 10.1002/jnr.22427.
47. Stimulation of annexin A5 expression by gonadotropin releasing hormone (GnRH) in the Leydig cells of rats. Yao B and Kawaminami M, J Reprod Dev. 2008 Aug;54(4):259-64. Epub 2008 May 27.
48. Testicular annexin A5 expression augmented by experimental cryptorchidism and could affect germ cell apoptosis in rats. Yao B, etal., Urology. 2009 Jun;73(6):1412-6. doi: 10.1016/j.urology.2008.11.021. Epub 2009 Apr 18.
Additional References at PubMed
PMID:2138016   PMID:7583670   PMID:9609693   PMID:12865345   PMID:16085777   PMID:16455971   PMID:17082577   PMID:19056867   PMID:19623612   PMID:19893283   PMID:19934022   PMID:19946888  
PMID:20458337   PMID:20978343   PMID:21362503   PMID:21423176   PMID:21508411   PMID:22871113   PMID:23376485   PMID:23533145   PMID:25002582   PMID:26316108   PMID:28543594   PMID:31515275  
PMID:33840679   PMID:37595881  


Genomics

Comparative Map Data
Anxa5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82121,242,133 - 121,272,935 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2121,242,136 - 121,281,400 (-)EnsemblGRCr8
mRatBN7.22119,314,007 - 119,344,703 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2119,314,007 - 119,353,369 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2125,868,632 - 125,899,139 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02123,981,142 - 124,011,637 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02118,610,122 - 118,640,625 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02123,162,477 - 123,194,730 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2123,162,461 - 123,193,130 (-)Ensemblrn6Rnor6.0
Rnor_5.02142,777,624 - 142,808,420 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42122,949,210 - 122,979,757 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2114,271,560 - 114,302,133 (-)NCBICelera
RGSC_v3.12122,894,171 - 122,924,719 (-)NCBI
RH 3.4 Map2623.7RGD
Cytogenetic Map2q25NCBI
ANXA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384121,667,946 - 121,696,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4121,667,396 - 121,697,061 (-)Ensemblhg38GRCh38
GRCh374122,589,101 - 122,618,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364122,808,598 - 122,837,626 (-)NCBIBuild 36Build 36hg18NCBI36
Build 344122,946,752 - 122,975,781NCBI
Celera4119,974,664 - 120,003,661 (-)NCBICelera
Cytogenetic Map4q27ENTREZGENE
HuRef4118,316,005 - 118,345,109 (-)NCBIHuRef
CHM1_14122,565,582 - 122,594,573 (-)NCBICHM1_1
T2T-CHM13v2.04124,971,975 - 125,001,007 (-)NCBIT2T-CHM13v2.0
Anxa5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39336,503,072 - 36,530,036 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl336,503,072 - 36,530,043 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38336,448,923 - 36,475,887 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl336,448,923 - 36,475,894 (-)Ensemblmm10GRCm38
MGSCv37336,347,845 - 36,374,809 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36336,640,474 - 36,667,247 (-)NCBIMGSCv36mm8
Celera336,332,154 - 36,359,060 (-)NCBICelera
Cytogenetic Map3BNCBI
cM Map317.46NCBI
Anxa5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542818,873,782 - 18,907,955 (+)Ensembl
ChiLan1.0NW_00495542818,873,782 - 18,907,955 (+)NCBIChiLan1.0ChiLan1.0
ANXA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23119,463,763 - 119,492,850 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14119,732,681 - 119,761,758 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04113,868,218 - 113,897,243 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14125,006,038 - 125,034,972 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4125,006,038 - 125,034,972 (-)EnsemblpanPan2panpan1.1
ANXA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11918,419,936 - 18,450,088 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1918,407,587 - 18,570,378 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1918,636,905 - 18,666,325 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01918,538,322 - 18,568,429 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1918,538,347 - 18,569,685 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11918,489,737 - 18,519,390 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01918,771,009 - 18,800,422 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01919,247,832 - 19,277,209 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Anxa5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530166,159,815 - 66,193,477 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936662925,940 - 939,451 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936662926,302 - 959,964 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANXA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8102,388,103 - 102,425,750 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18102,387,833 - 102,420,868 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28109,609,049 - 109,641,864 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANXA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1768,940,365 - 68,970,324 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl768,940,304 - 68,970,811 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603747,900,616 - 47,930,596 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anxa5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247771,919,602 - 1,970,059 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247771,921,354 - 1,969,772 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Anxa5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13117,508,000 - 117,538,898 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Anxa5
24 total Variants
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir1rno-miR-1-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23436819

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:50
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000019554
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)2105628029150628029Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)282947902127947902Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)284056790132859658Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
2317886Alcrsp23Alcohol response QTL 232.40.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)295142371140142371Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2120039407159440891Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2100807373145807373Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2106869825151869825Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
5135226Leukc2Leukocyte quantity QTL 2eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)2120039407151869825Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)293602631145807373Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)282214549127214549Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
7488933Bp368Blood pressure QTL 3680.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2104957381149957381Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2120339555165339555Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2114032149150226270Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)2114440891159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1354594Despr10Despair related QTL 102e-06locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2116804572161804572Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat

Markers in Region
RH129836  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22119,314,032 - 119,314,235 (+)MAPPERmRatBN7.2
Rnor_6.02123,162,503 - 123,162,705NCBIRnor6.0
Rnor_5.02142,777,650 - 142,777,852UniSTSRnor5.0
RGSC_v3.42122,949,218 - 122,949,420UniSTSRGSC3.4
Celera2114,271,568 - 114,271,770UniSTS
RH 3.4 Map2664.1UniSTS
Cytogenetic Map2q25UniSTS
RH94545  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22119,314,025 - 119,314,207 (+)MAPPERmRatBN7.2
Rnor_6.02123,162,496 - 123,162,677NCBIRnor6.0
Rnor_5.02142,777,643 - 142,777,824UniSTSRnor5.0
RGSC_v3.42122,949,211 - 122,949,392UniSTSRGSC3.4
Celera2114,271,561 - 114,271,742UniSTS
RH 3.4 Map2623.7UniSTS
Cytogenetic Map2q25UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF051895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D42137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC533519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M21730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019554   ⟹   ENSRNOP00000019552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2121,242,136 - 121,272,960 (-)Ensembl
mRatBN7.2 Ensembl2119,314,010 - 119,344,795 (-)Ensembl
Rnor_6.0 Ensembl2123,162,461 - 123,193,130 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104744   ⟹   ENSRNOP00000087773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2121,242,136 - 121,260,351 (-)Ensembl
mRatBN7.2 Ensembl2119,314,007 - 119,344,610 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108710   ⟹   ENSRNOP00000090883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2121,242,136 - 121,260,350 (-)Ensembl
mRatBN7.2 Ensembl2119,314,010 - 119,344,795 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109811   ⟹   ENSRNOP00000086538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2121,242,136 - 121,260,551 (-)Ensembl
mRatBN7.2 Ensembl2119,314,007 - 119,344,600 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111490   ⟹   ENSRNOP00000097911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2121,242,136 - 121,281,400 (-)Ensembl
mRatBN7.2 Ensembl2119,314,014 - 119,353,369 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113833   ⟹   ENSRNOP00000082480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2119,314,014 - 119,332,426 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116052   ⟹   ENSRNOP00000088704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2119,314,014 - 119,353,369 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116908   ⟹   ENSRNOP00000094623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2121,242,136 - 121,274,646 (-)Ensembl
mRatBN7.2 Ensembl2119,314,014 - 119,353,369 (-)Ensembl
RefSeq Acc Id: NM_013132   ⟹   NP_037264
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82121,242,151 - 121,272,696 (-)NCBI
mRatBN7.22119,314,025 - 119,344,571 (-)NCBI
Rnor_6.02123,162,495 - 123,193,040 (-)NCBI
Rnor_5.02142,777,624 - 142,808,420 (-)NCBI
RGSC_v3.42122,949,210 - 122,979,757 (-)RGD
Celera2114,271,560 - 114,302,133 (-)RGD
Sequence:
RefSeq Acc Id: XM_006232268   ⟹   XP_006232330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82121,242,133 - 121,272,925 (-)NCBI
mRatBN7.22119,314,007 - 119,344,703 (-)NCBI
Rnor_6.02123,162,477 - 123,193,175 (-)NCBI
Rnor_5.02142,777,624 - 142,808,420 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063281375   ⟹   XP_063137445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82121,242,133 - 121,272,935 (-)NCBI
RefSeq Acc Id: NP_037264   ⟸   NM_013132
- UniProtKB: P14668 (UniProtKB/Swiss-Prot),   Q66HH8 (UniProtKB/TrEMBL),   A6IHX7 (UniProtKB/TrEMBL),   A0A8I6GGH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232330   ⟸   XM_006232268
- Peptide Label: isoform X2
- UniProtKB: P14668 (UniProtKB/Swiss-Prot),   Q66HH8 (UniProtKB/TrEMBL),   A6IHX7 (UniProtKB/TrEMBL),   A0A8I6GGH9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019552   ⟸   ENSRNOT00000019554
Ensembl Acc Id: ENSRNOP00000086538   ⟸   ENSRNOT00000109811
Ensembl Acc Id: ENSRNOP00000097911   ⟸   ENSRNOT00000111490
Ensembl Acc Id: ENSRNOP00000094623   ⟸   ENSRNOT00000116908
Ensembl Acc Id: ENSRNOP00000090883   ⟸   ENSRNOT00000108710
Ensembl Acc Id: ENSRNOP00000082480   ⟸   ENSRNOT00000113833
Ensembl Acc Id: ENSRNOP00000088704   ⟸   ENSRNOT00000116052
Ensembl Acc Id: ENSRNOP00000087773   ⟸   ENSRNOT00000104744
RefSeq Acc Id: XP_063137445   ⟸   XM_063281375
- Peptide Label: isoform X1
- UniProtKB: O70371 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P14668-F1-model_v2 AlphaFold P14668 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691289
Promoter ID:EPDNEW_R1814
Type:initiation region
Name:Anxa5_1
Description:annexin A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02123,193,087 - 123,193,147EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2120 AgrOrtholog
BioCyc Gene G2FUF-53319 BioCyc
Ensembl Genes ENSRNOG00000014453 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000019554 ENTREZGENE
  ENSRNOT00000111490 ENTREZGENE
Gene3D-CATH 1.10.220.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7192977 IMAGE-MGC_LOAD
InterPro Annexin UniProtKB/Swiss-Prot
  Annexin_repeat UniProtKB/Swiss-Prot
  Annexin_repeat_CS UniProtKB/Swiss-Prot
  Annexin_sf UniProtKB/Swiss-Prot
  ANX5 UniProtKB/Swiss-Prot
KEGG Report rno:25673 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93655 IMAGE-MGC_LOAD
NCBI Gene 25673 ENTREZGENE
PANTHER ANNEXIN UniProtKB/Swiss-Prot
  PTHR10502:SF26 UniProtKB/Swiss-Prot
Pfam Annexin UniProtKB/Swiss-Prot
PhenoGen Anxa5 PhenoGen
PRINTS ANNEXIN UniProtKB/Swiss-Prot
  ANNEXINV UniProtKB/Swiss-Prot
PROSITE ANNEXIN UniProtKB/Swiss-Prot
  ANNEXIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014453 RatGTEx
SMART ANX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47874 UniProtKB/Swiss-Prot
UniProt A0A6F8X2H2_RAT UniProtKB/TrEMBL
  A0A8I6A3S1_RAT UniProtKB/TrEMBL
  A0A8I6A6E5_RAT UniProtKB/TrEMBL
  A0A8I6ADG8_RAT UniProtKB/TrEMBL
  A0A8I6AM08_RAT UniProtKB/TrEMBL
  A0A8I6AS27_RAT UniProtKB/TrEMBL
  A0A8I6GGH9 ENTREZGENE, UniProtKB/TrEMBL
  A6IHX7 ENTREZGENE
  A6IHX8_RAT UniProtKB/TrEMBL
  ANXA5_RAT UniProtKB/Swiss-Prot
  F7FN61_RAT UniProtKB/TrEMBL
  O70371 ENTREZGENE, UniProtKB/TrEMBL
  P14668 ENTREZGENE
  Q66HH8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Anxa5  annexin A5    annexin 5  Name updated 1299863 APPROVED
2002-11-06 Anxa5  annexin 5  Anx5  Annexin V  Symbol and Name updated 625702 APPROVED
2002-06-10 Anx5  Annexin V      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in all tissues examined 634647
gene_function binds phospholipid membranes, binding is calcium dependent 634648
gene_product member of a family of calcium and phospholipid binding proteins 634647
gene_product member of a family of calcium and phospholipid binding proteins 634648
gene_transcript at least four distinct transcripts are detected that may arise via alternative splicing 634647