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Gene: Anxa1 (annexin A1) Rattus norvegicus
Symbol: Anxa1
Name: annexin A1
RGD ID: 2118
Description: Exhibits several functions, including double-stranded DNA helicase activity; nucleic acid binding activity; and phospholipase A2 inhibitor activity. Contributes to single-stranded RNA binding activity. Involved in several processes, including estrous cycle; gland development; and peptide hormone secretion. Localizes to several cellular components, including mast cell granule; mitochondrial membrane; and synaptic membrane. Predicted to colocalize with actin filament. Used to study acute kidney failure; brain ischemia; pleurisy; and uveitis. Biomarker of several diseases, including carcinoma (multiple); cerebral infarction; eye disease (multiple); hyperthyroidism; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in brain ischemia and pancreatic cancer. Orthologous to human ANXA1 (annexin A1); PARTICIPATES IN cyclooxygenase mediated pathway of arachidonic acid metabolism; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
Also known as: annexin 1; Annexin 1 (p35) (Lipocortin 1); annexin I; annexin-1; Anx1; calpactin II; calpactin-2; chromobindin-9; lipocortin 1; lipocortin I; p35; phospholipase A2 inhibitory protein
Homo sapiens (human) : ANXA1 (annexin A1)  HGNC  Alliance
Mus musculus (house mouse) : Anxa1 (annexin A1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Anxa1 (annexin A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANXA1 (annexin A1)
Canis lupus familiaris (dog) : ANXA1 (annexin A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Anxa1 (annexin A1)
Sus scrofa (pig) : ANXA1 (annexin A1)
Chlorocebus sabaeus (African green monkey) : ANXA1 (annexin A1)
Heterocephalus glaber (naked mole-rat) : Anxa1 (annexin A1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01237,893,983 - 237,910,002 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1237,893,966 - 237,910,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,192,875 - 245,220,057 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,478,436 - 223,494,455 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11223,642,460 - 223,658,478 (-)NCBI
Celera1215,138,950 - 215,154,969 (-)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Anxa1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2118
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.