Aldoa (aldolase, fructose-bisphosphate A) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Aldoa (aldolase, fructose-bisphosphate A) Rattus norvegicus
Analyze
Symbol: Aldoa
Name: aldolase, fructose-bisphosphate A
RGD ID: 2089
Description: Predicted to enable several functions, including fructose binding activity; fructose-bisphosphate aldolase activity; and identical protein binding activity. Involved in several processes, including methylglyoxal biosynthetic process; response to estrogen; and response to lipopolysaccharide. Located in cytoplasm and heterochromatin. Orthologous to human ALDOA (aldolase, fructose-bisphosphate A); PARTICIPATES IN Fanconi syndrome pathway; fructose and mannose metabolic pathway; fructose-1,6-bisphosphatase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Aldo1; aldolase A; Aldolase A fructose-bisphosphate; aldolase A, fructose-bisphosphate; fructose-bisphosphate aldolase A; muscle-type aldolase; RNALDOG5
RGD Orthologs
Human
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Aldoa-ps1   Aldoa-ps2   Aldoa-ps3   Aldoa-ps4   Aldoa-ps5   Aldoa-ps6   Aldoa-ps7  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,832,820 - 190,838,021 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1190,832,820 - 190,838,211 (-)EnsemblGRCr8
mRatBN7.21181,402,275 - 181,407,476 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,402,275 - 181,406,182 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,753,603 - 189,758,803 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,939,676 - 196,944,877 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,607,009 - 189,612,203 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,228,387 - 198,233,988 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,228,387 - 198,233,588 (-)Ensemblrn6Rnor6.0
Rnor_5.01205,208,255 - 205,213,627 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,970,658 - 185,974,615 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1179,057,793 - 179,062,995 (-)NCBICelera
RGSC_v3.11186,120,538 - 186,124,496 (-)NCBI
RH 2.0 Map1968.2RGD
Cytogenetic Map1q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,10-phenanthroline  (ISO)
1-naphthyl isothiocyanate  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
ampicillin  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arotinoid acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
beta-D-fructofuranose 1,6-bisphosphate  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcidiol  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chloroacetaldehyde  (ISO)
chloroform  (EXP)
chloropicrin  (ISO)
chlorpromazine  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
clozapine  (EXP)
cobalt dichloride  (EXP,ISO)
cobalt(2+) sulfate  (ISO)
copper(II) chloride  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-fructofuranose 1,6-bisphosphate  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethyl maleate  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dopamine  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP)
fenvalerate  (EXP)
flutamide  (EXP)
FR900359  (ISO)
furan  (EXP)
furfural  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
haloperidol  (EXP)
ibuprofen  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
isoflavones  (EXP)
ivermectin  (ISO)
keto-D-fructose 1,6-bisphosphate  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (EXP)
Macrosphelide A  (ISO)
manganese(II) chloride  (EXP)
metformin  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
metronidazole  (EXP)
N-nitrosodiethylamine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
nefazodone  (EXP)
neomycin  (EXP)
nitrofurantoin  (EXP)
obeticholic acid  (ISO)
okadaic acid  (ISO)
ozone  (EXP)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
PhIP  (EXP)
phorone  (EXP)
pirinixic acid  (EXP)
quercetin  (EXP,ISO)
quinidine  (EXP)
ranitidine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
sarin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP)
tetracycline  (EXP)
thapsigargin  (EXP)
thifluzamide  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
XAV939  (ISO)
Yessotoxin  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin cytoskeleton  (ISO)
cytoplasm  (IDA,IEA,ISO)
cytosol  (IBA)
extracellular exosome  (ISO)
heterochromatin  (IDA,ISO)
I band  (IEA)
M band  (IEA)
sperm head  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Estrogen regulation of the rat anterior pituitary gland proteome. Blake CA, etal., Exp Biol Med (Maywood). 2005 Dec;230(11):800-7.
2. Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma. Cui Y, etal., Pancreatology. 2009;9(1-2):89-98. Epub 2008 Dec 12.
3. Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine. Dukes AA, etal., J Neurochem. 2008 Jul;106(1):333-46. Epub 2008 Jul 1.
4. Simvastatin induces apoptosis of cultured rat cardiomyocytes. El-Ani D and Zimlichman R, J Basic Clin Physiol Pharmacol. 2001;12(4):325-38.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Location of adult and fetal aldolases A, B, and C by immunoperoxidase technique in LF fast-growing rat hepatomas. Hatzfeld A, etal., Cancer Res. 1978 Jan;38(1):16-22.
8. Proteins differentially expressed in response to nicotine in five rat brain regions: identification using a 2-DE/MS-based proteomics approach. Hwang YY and Li MD, Proteomics. 2006 May;6(10):3138-53.
9. Identification of major Ca(2+)/calmodulin-dependent protein kinase phosphatase-binding proteins in brain: biochemical analysis of the interaction. Ishida A, etal., Arch Biochem Biophys. 2005 Mar 1;435(1):134-46.
10. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
11. Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome. Liu J, etal., Cardiovasc Res. 2011 Dec 1;92(3):494-503. doi: 10.1093/cvr/cvr239. Epub 2011 Sep 2.
12. Aldolase A is present in smooth muscle cell nuclei. Mamczur P and Dzugaj A, Acta Biochim Pol. 2008;55(4):799-805. Epub 2008 Dec 16.
13. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
14. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans. Oppelt SA, etal., Mol Genet Metab. 2015 Mar;114(3):445-50. doi: 10.1016/j.ymgme.2015.01.001. Epub 2015 Jan 22.
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
19. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
20. GOA pipeline RGD automated data pipeline
21. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Comprehensive gene review and curation RGD comprehensive gene curation
24. Aldolase variants: structure and physiological significance. Rutter WJ, etal., Ann N Y Acad Sci. 1968 Jun 14;151(1):102-17.
25. LPS increases hepatic HIF-1alpha protein and expression of the HIF-1-dependent gene aldolase A in rats. Scharte M, etal., J Surg Res. 2006 Oct;135(2):262-7. Epub 2006 Aug 23.
26. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
27. Differential activation of some transcription factors during rat liver ischemia, reperfusion, and heat shock. Tacchini L, etal., J Cell Physiol. 1999 Aug;180(2):255-62.
28. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
29. Two different aldolase A mRNA species in rat tissues. Tsutsumi R, etal., Eur J Biochem 1984 Jul 2;142(1):161-4.
Additional References at PubMed
PMID:1959592   PMID:2416636   PMID:3753977   PMID:3783705   PMID:6696436   PMID:8780723   PMID:9244396   PMID:10048322   PMID:11785984   PMID:12519789   PMID:14615364   PMID:14760703  
PMID:14766013   PMID:15277470   PMID:15389646   PMID:15489334   PMID:16687649   PMID:17634366   PMID:17641064   PMID:17659271   PMID:18676612   PMID:18698006   PMID:19056867   PMID:19199708  
PMID:19946888   PMID:20458337   PMID:21482559   PMID:21630459   PMID:22206666   PMID:22681889   PMID:22871113   PMID:23106098   PMID:23355646   PMID:23376485   PMID:23495010   PMID:23533145  
PMID:23580065   PMID:24006456   PMID:25416956   PMID:25468996   PMID:26316108   PMID:29476059   PMID:32357304   PMID:36755387  


Genomics

Comparative Map Data
Aldoa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,832,820 - 190,838,021 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1190,832,820 - 190,838,211 (-)EnsemblGRCr8
mRatBN7.21181,402,275 - 181,407,476 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,402,275 - 181,406,182 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,753,603 - 189,758,803 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,939,676 - 196,944,877 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,607,009 - 189,612,203 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,228,387 - 198,233,988 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,228,387 - 198,233,588 (-)Ensemblrn6Rnor6.0
Rnor_5.01205,208,255 - 205,213,627 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,970,658 - 185,974,615 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1179,057,793 - 179,062,995 (-)NCBICelera
RGSC_v3.11186,120,538 - 186,124,496 (-)NCBI
RH 2.0 Map1968.2RGD
Cytogenetic Map1q36NCBI
ALDOA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,064,279 - 30,070,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,064,164 - 30,070,457 (+)Ensemblhg38GRCh38
GRCh371630,075,600 - 30,081,741 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map16p11.2NCBI
HuRef1627,725,968 - 27,743,009 (+)NCBIHuRef
CHM1_11631,280,168 - 31,297,498 (+)NCBICHM1_1
T2T-CHM13v2.01630,346,925 - 30,353,065 (+)NCBIT2T-CHM13v2.0
ALDOA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,814,063 - 30,820,272 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,405,588 - 35,411,803 (-)NCBINHGRI_mPanPan1
ALDOA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,077,241 - 18,083,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,655,871 - 19,661,649 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0618,213,209 - 18,218,992 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,205,846 - 18,218,992 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,012,169 - 18,017,945 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,927,573 - 17,933,346 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,243,185 - 18,248,968 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
ALDOA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,253,384 - 18,260,163 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1318,246,036 - 18,260,167 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ALDOA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl526,588,868 - 26,592,112 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660682,944,202 - 2,950,473 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Aldoa
18 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:45
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000032362
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
61326Eae6Experimental allergic encephalomyelitis QTL 65.3body mass (VT:0001259)change in body weight (CMO:0002045)1172949660181830018Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1123556856242907031Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1117917486196963478Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1123556856196963478Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
2325725Eae31Experimental allergic encephalomyelitis QTL 31nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1178810256188377506Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1174133260196383668Rat

Markers in Region
D1Arb19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,406,902 - 181,407,091 (+)MAPPERmRatBN7.2
Rnor_6.01198,233,015 - 198,233,203NCBIRnor6.0
Rnor_5.01205,212,888 - 205,213,076UniSTSRnor5.0
RGSC_v3.41185,975,285 - 185,975,474RGDRGSC3.4
RGSC_v3.41185,975,286 - 185,975,474UniSTSRGSC3.4
Celera1179,062,422 - 179,062,610UniSTS
RGSC_v3.11186,125,166 - 186,125,355RGD
Cytogenetic Map1q36UniSTS
D1Mco16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,402,086 - 181,402,308 (+)MAPPERmRatBN7.2
Rnor_6.01198,228,199 - 198,228,420NCBIRnor6.0
Rnor_5.01205,208,067 - 205,208,288UniSTSRnor5.0
RGSC_v3.41185,970,469 - 185,970,691RGDRGSC3.4
RGSC_v3.41185,970,470 - 185,970,691UniSTSRGSC3.4
Celera1179,057,605 - 179,057,826UniSTS
RGSC_v3.11186,120,350 - 186,120,572RGD
Cytogenetic Map1q36UniSTS
D1Wox41  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,406,863 - 181,406,982 (+)MAPPERmRatBN7.2
Rnor_6.01198,232,976 - 198,233,094NCBIRnor6.0
Rnor_5.01205,212,849 - 205,212,967UniSTSRnor5.0
RGSC_v3.41185,975,247 - 185,975,365UniSTSRGSC3.4
Celera1179,062,383 - 179,062,501UniSTS
Cytogenetic Map1q36UniSTS
RH47250  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,402,672 - 181,402,798 (+)MAPPERmRatBN7.2
mRatBN7.21334,330,138 - 34,330,264 (+)MAPPERmRatBN7.2
Rnor_6.01339,163,263 - 39,163,388NCBIRnor6.0
Rnor_6.01198,228,785 - 198,228,910NCBIRnor6.0
Rnor_5.01344,288,027 - 44,288,152UniSTSRnor5.0
Rnor_5.01205,208,653 - 205,208,778UniSTSRnor5.0
RGSC_v3.41185,971,056 - 185,971,181UniSTSRGSC3.4
RGSC_v3.41335,262,315 - 35,262,440UniSTSRGSC3.4
Celera1334,151,560 - 34,151,685UniSTS
Celera1179,058,191 - 179,058,316UniSTS
Cytogenetic Map1q36UniSTS
ALDOA  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21829,096,639 - 29,096,885 (+)MAPPERmRatBN7.2
Rnor_6.01830,466,289 - 30,466,534NCBIRnor6.0
Rnor_5.01830,173,484 - 30,173,729UniSTSRnor5.0
RGSC_v3.41830,200,938 - 30,201,183UniSTSRGSC3.4
Celera1828,792,419 - 28,792,664UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map1q36UniSTS
Aldoa  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21829,095,655 - 29,096,644 (+)MAPPERmRatBN7.2
Rnor_6.01830,465,305 - 30,466,293NCBIRnor6.0
Rnor_5.01830,172,500 - 30,173,488UniSTSRnor5.0
RGSC_v3.41830,199,954 - 30,200,942UniSTSRGSC3.4
Celera1828,791,435 - 28,792,423UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map1q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001177305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC064440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB750468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF975930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO383722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO398643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000080988   ⟹   ENSRNOP00000068764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1190,832,820 - 190,836,731 (-)Ensembl
mRatBN7.2 Ensembl1181,402,275 - 181,406,182 (-)Ensembl
Rnor_6.0 Ensembl1198,228,387 - 198,232,344 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087928   ⟹   ENSRNOP00000069507
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1190,832,820 - 190,836,821 (-)Ensembl
mRatBN7.2 Ensembl1181,402,275 - 181,406,182 (-)Ensembl
Rnor_6.0 Ensembl1198,228,387 - 198,233,215 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088473   ⟹   ENSRNOP00000069540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1190,832,820 - 190,838,211 (-)Ensembl
Rnor_6.0 Ensembl1198,228,387 - 198,233,588 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112001   ⟹   ENSRNOP00000093578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1190,832,820 - 190,836,797 (-)Ensembl
mRatBN7.2 Ensembl1181,402,437 - 181,406,181 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000169085   ⟹   ENSRNOP00000111387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1190,832,820 - 190,838,211 (-)Ensembl
RefSeq Acc Id: NM_001177305   ⟹   NP_001170776
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81190,832,820 - 190,837,648 (-)NCBI
mRatBN7.21181,402,275 - 181,407,103 (-)NCBI
Rnor_6.01198,228,387 - 198,233,215 (-)NCBI
Rnor_5.01205,208,255 - 205,213,627 (-)NCBI
Celera1179,057,793 - 179,062,622 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271536   ⟹   NP_001258465
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81190,832,820 - 190,838,021 (-)NCBI
mRatBN7.21181,402,275 - 181,407,476 (-)NCBI
Rnor_6.01198,228,387 - 198,233,588 (-)NCBI
Rnor_5.01205,208,255 - 205,213,627 (-)NCBI
Celera1179,057,793 - 179,062,995 (-)NCBI
Sequence:
RefSeq Acc Id: NM_012495   ⟹   NP_036627
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81190,832,820 - 190,836,777 (-)NCBI
mRatBN7.21181,402,275 - 181,406,232 (-)NCBI
Rnor_6.01198,228,387 - 198,232,344 (-)NCBI
Rnor_5.01205,208,255 - 205,213,627 (-)NCBI
RGSC_v3.41185,970,658 - 185,974,615 (-)RGD
Celera1179,057,793 - 179,061,750 (-)NCBI
Sequence:
RefSeq Acc Id: NP_036627   ⟸   NM_012495
- UniProtKB: Q63038 (UniProtKB/Swiss-Prot),   P05065 (UniProtKB/Swiss-Prot),   A6I9E6 (UniProtKB/TrEMBL),   A0A8L2R123 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001170776   ⟸   NM_001177305
- UniProtKB: Q63038 (UniProtKB/Swiss-Prot),   P05065 (UniProtKB/Swiss-Prot),   A6I9E6 (UniProtKB/TrEMBL),   A0A8L2R123 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258465   ⟸   NM_001271536
- UniProtKB: Q63038 (UniProtKB/Swiss-Prot),   P05065 (UniProtKB/Swiss-Prot),   A6I9E6 (UniProtKB/TrEMBL),   A0A8L2R123 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069507   ⟸   ENSRNOT00000087928
Ensembl Acc Id: ENSRNOP00000068764   ⟸   ENSRNOT00000080988
Ensembl Acc Id: ENSRNOP00000069540   ⟸   ENSRNOT00000088473
Ensembl Acc Id: ENSRNOP00000093578   ⟸   ENSRNOT00000112001
Ensembl Acc Id: ENSRNOP00000111387   ⟸   ENSRNOT00000169085

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05065-F1-model_v2 AlphaFold P05065 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690413
Promoter ID:EPDNEW_R936
Type:initiation region
Name:Aldoa_2
Description:aldolase, fructose-bisphosphate A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R937  EPDNEW_R938  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01198,232,297 - 198,232,357EPDNEW
RGD ID:13690414
Promoter ID:EPDNEW_R937
Type:multiple initiation site
Name:Aldoa_1
Description:aldolase, fructose-bisphosphate A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R936  EPDNEW_R938  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01198,233,219 - 198,233,279EPDNEW
RGD ID:13690416
Promoter ID:EPDNEW_R938
Type:initiation region
Name:Aldoa_3
Description:aldolase, fructose-bisphosphate A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R936  EPDNEW_R937  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01198,233,553 - 198,233,613EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2089 AgrOrtholog
BioCyc Gene G2FUF-57418 BioCyc
BioCyc Pathway ANAGLYCOLYSIS-PWY [glycolysis III (from glucose)] BioCyc
  PWY66-373 [sucrose degradation V (sucrose alpha-glucosidase)] BioCyc
  PWY66-399 [gluconeogenesis III] BioCyc
BioCyc Pathway Image ANAGLYCOLYSIS-PWY BioCyc
  PWY66-373 BioCyc
  PWY66-399 BioCyc
Ensembl Genes ENSRNOG00000052802 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000088473 ENTREZGENE
  ENSRNOT00000112001 ENTREZGENE
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5623628 IMAGE-MGC_LOAD
InterPro Aldolase_I_AS UniProtKB/Swiss-Prot
  Aldolase_TIM UniProtKB/Swiss-Prot
  FBA_I UniProtKB/Swiss-Prot
KEGG Report rno:24189 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72550 IMAGE-MGC_LOAD
NCBI Gene 24189 ENTREZGENE
PANTHER PTHR11627 UniProtKB/Swiss-Prot
Pfam Glycolytic UniProtKB/Swiss-Prot
PhenoGen Aldoa PhenoGen
PROSITE ALDOLASE_CLASS_I UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000052802 RatGTEx
Superfamily-SCOP Aldolase UniProtKB/Swiss-Prot
TIGR TC204161
UniProt A0A8I6AKC0_RAT UniProtKB/TrEMBL
  A0A8L2R0P3_RAT UniProtKB/TrEMBL
  A0A8L2R123 ENTREZGENE, UniProtKB/TrEMBL
  A6I9D9_RAT UniProtKB/TrEMBL
  A6I9E2_RAT UniProtKB/TrEMBL
  A6I9E3_RAT UniProtKB/TrEMBL
  A6I9E6 ENTREZGENE, UniProtKB/TrEMBL
  A6I9E7_RAT UniProtKB/TrEMBL
  A6I9E8_RAT UniProtKB/TrEMBL
  A6I9E9_RAT UniProtKB/TrEMBL
  A6I9F2_RAT UniProtKB/TrEMBL
  ALDOA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q63038 ENTREZGENE
UniProt Secondary Q63038 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Aldoa  aldolase, fructose-bisphosphate A  Aldoa  aldolase A, fructose-bisphosphate  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Aldoa  aldolase A, fructose-bisphosphate  Aldoa  aldolase A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Aldoa  aldolase A    Aldolase A, fructose-bisphosphate  Name updated 625702 APPROVED
2002-06-10 Aldoa  Aldolase A, fructose-bisphosphate      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease expressed in hepatoma cells 632186
gene_product member of the aldolase enzyme family 632186
gene_transcript has three transcripts that differ in the 5 noncoding region 632186