Alb (albumin) - Rat Genome Database

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Gene: Alb (albumin) Rattus norvegicus
Symbol: Alb
Name: albumin
RGD ID: 2085
Description: Enables several functions, including fatty acid binding activity; modified amino acid binding activity; and zinc ion binding activity. Involved in several processes, including positive regulation of circadian sleep/wake cycle, non-REM sleep; response to biphenyl; and response to platinum ion. Located in basement membrane and extracellular space. Used to study familial hyperlipidemia. Biomarker of Reye syndrome; obstructive jaundice; and protein-energy malnutrition. Human ortholog(s) of this gene implicated in several diseases, including blood protein disease; hepatobiliary system cancer (multiple); hyperthyroxinemia; middle cerebral artery infarction; and psoriasis. Orthologous to human ALB (albumin); PARTICIPATES IN forkhead class A signaling pathway; organophosphate response pathway; INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; (R,R,R)-alpha-tocopherol.
Type: protein-coding
Previously known as: Alb1; Albza; serum albumin
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
GRCr81417,891,564 - 17,907,043 (-)NCBIGRCr8
mRatBN7.21417,607,397 - 17,622,814 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,607,381 - 17,622,836 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,592,501 - 17,607,638 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,911,425 - 18,926,564 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,610,395 - 17,625,561 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01419,176,275 - 19,191,793 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1419,176,277 - 19,191,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01419,083,045 - 19,098,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41419,126,935 - 19,142,214 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11419,126,964 - 19,142,199 (-)NCBI
Celera1416,973,318 - 16,987,975 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
acute kidney failure  (ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (IDA)
adult respiratory distress syndrome  (ISO)
Albuminuria  (IEP,ISO)
alcoholic hepatitis  (ISO)
allergic disease  (ISO)
Analbuminemia  (ISO)
angioedema  (ISO)
Animal Disease Models  (ISO)
anuria  (ISO)
aseptic meningitis  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
azoospermia  (ISO)
biliary tract benign neoplasm  (ISO)
blood protein disease  (ISO)
brain disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Burns  (ISO)
Carcinoid Tumor  (ISO)
cardiovascular system disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemically-Induced Disorders  (ISO)
cholangiocarcinoma  (ISO)
cholestasis  (ISO)
Chronic Allograft Nephropathy  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
Delayed Hypersensitivity  (ISO)
depressive disorder  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (IEP,ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
echinococcosis  (ISO)
Ehlers-Danlos syndrome arthrochalasia type 1  (ISO)
end stage renal disease  (ISO)
epilepsy  (ISO)
esophageal varix  (ISO)
Experimental Arthritis  (ISO)
Experimental Liver Cirrhosis  (IEP,ISO)
Experimental Sarcoma  (ISO)
extrahepatic cholestasis  (ISO)
Familial Dysalbuminemic Hyperthyroxinemia  (ISO)
familial hyperlipidemia  (IAGP)
Fibrosis  (ISO)
gastric cardia adenocarcinoma  (ISO)
genetic disease  (ISO)
glomerulonephritis  (ISO)
Hantavirus hemorrhagic fever with renal syndrome  (ISO)
heart disease  (ISO)
hemolytic-uremic syndrome  (ISO)
Hepatic Insufficiency  (ISO)
hepatitis  (ISO)
hepatocellular carcinoma  (ISO)
Hepatomegaly  (ISO)
HIV Seropositivity  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hydrops Fetalis  (ISO)
hypertension  (ISO)
hyperthyroxinemia  (ISO)
Hypoalbuminemia  (ISO)
Hypoproteinemia  (IAGP,ISO)
Hypotension  (ISO)
interstitial nephritis  (ISO)
Keloid  (ISO)
kidney disease  (ISO)
leukemia  (ISO)
liver cirrhosis  (ISO)
lung adenocarcinoma  (ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
membranoproliferative glomerulonephritis  (ISO)
membranous glomerulonephritis  (ISO)
middle cerebral artery infarction  (ISO)
multiple myeloma  (ISO)
muscular disease  (ISO)
Myocardial Reperfusion Injury  (ISO)
nephritis  (ISO)
nephrosis  (ISO)
nephrotic syndrome  (ISO)
obstructive jaundice  (IEP)
Occupational Diseases  (ISO)
Pain  (ISO)
pancreas disease  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
Pancreatic Fistula  (ISO)
pancreatitis  (ISO)
Paroxysmal Atrial Fibrillation  (ISO)
Perennial Allergic Rhinitis  (ISO)
pneumonia  (ISO)
Poisoning  (ISO)
Postoperative Complications  (ISO)
pre-eclampsia  (ISO)
primary biliary cholangitis  (ISO)
protein-energy malnutrition  (IEP)
proteinuria  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
Reperfusion Injury  (IEP)
respiratory system disease  (ISO)
Reye syndrome  (IEP)
root caries  (ISO)
Sepsis  (ISO)
Serum Sickness  (ISO)
Stevens-Johnson syndrome  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
suppurative otitis media  (ISO)
thrombocytopenia  (ISO)
twin-to-twin transfusion syndrome  (ISO)
ulcerative colitis  (ISO)
urticaria  (ISO)
uveitis  (ISO)
Zollinger-Ellison syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
(E)-1,3-dichloropropene  (ISO)
(R)-lipoic acid  (EXP,ISO)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2-benzoquinone  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1,2-naphthoquinone  (ISO)
1,3-dinitrobenzene  (EXP)
1,4-benzoquinone  (EXP,ISO)
1,4-naphthoquinone  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-Cyano-2-hydroxy-3-butene  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,5'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-D  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,6-dihydroxybenzoic acid  (ISO)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-galactopyranose  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-fluorobenzoic acid  (ISO)
2-Methoxy-4-methylphenol  (ISO)
2-methoxyethanol  (EXP)
2-propionyl-6-dimethylaminonaphthalene  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3,5-dihydroxybenzoic acid  (ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-fluorobenzoic acid  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4,4'-methylene-bis-(2-chloroaniline)  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-aminophenol  (EXP)
4-Ethyl-2-methoxyphenol  (ISO)
4-fluorobenzoic acid  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitroaniline  (EXP)
4-nitrophenol  (EXP,ISO)
5,5-dimethyl-1-pyrroline N-oxide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (ISO)
5-butyl-1-cyclohexylbarbituric acid  (ISO)
5-fluorouracil  (ISO)
5-formyltetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
7,8-dihydroxycoumarin  (EXP)
8-Br-cAMP  (ISO)
9-anthroic acid  (ISO)
abacavir  (ISO)
acetamide  (EXP)
acetohexamide  (ISO)
acetylcholine  (ISO)
acetylsalicylic acid  (ISO)
acid red 29  (ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP)
alcohol  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (EXP,ISO)
aldosterone  (ISO)
alfacalcidol  (ISO)
all-trans-retinal  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allicin  (ISO)
alpha-amanitin  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiloride  (EXP)
aminoguanidine  (EXP,ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
amsacrine  (ISO)
aniline  (EXP,ISO)
anthracen-2-amine  (EXP)
anthraflavic acid  (ISO)
apocynin  (EXP)
aristolochic acid A  (EXP,ISO)
arotinoid acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
astaxanthin  (EXP)
atazanavir sulfate  (ISO)
atrazine  (EXP,ISO)
auranofin  (ISO)
Azaspiracid  (ISO)
azathioprine  (EXP)
bafilomycin A1  (ISO)
baicalin  (ISO)
barium chloride  (EXP)
barium sulfate  (EXP)
benoxaprofen  (ISO)
bentazone  (EXP)
benzalkonium chloride  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (EXP)
beta-D-glucosamine  (EXP)
beta-naphthoflavone  (ISO)
bilirubin IXalpha  (EXP,ISO)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis-4-nitrophenyl phosphate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Brevetoxin B  (ISO)
bromobenzene  (EXP)
Bromocresolgreen  (ISO)
buta-1,3-diene  (ISO)
butachlor  (ISO)
butane-2,3-dione  (EXP,ISO)
butyric acid  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcium silicate  (ISO)
Calphostin C  (ISO)
camptothecin  (ISO)
capsaicin  (ISO)
carbamazepine-10,11-epoxide  (ISO)
carbaryl  (EXP,ISO)
carbendazim  (EXP)
carbofuran  (EXP,ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
carnosine  (ISO)
celecoxib  (EXP)
ceric oxide  (EXP,ISO)
cerium trichloride  (ISO)
ceruletide  (EXP)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chlordecone  (EXP,ISO)
chlorogenic acid  (EXP,ISO)
chlorohydrocarbon  (ISO)
chloromethylisothiazolinone  (ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
choline  (EXP)
chromium trioxide  (EXP)
chrysazin  (ISO)
chrysin  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
clozapine  (EXP,ISO)
cobalt atom  (EXP,ISO)
cobalt dichloride  (EXP)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (EXP)
corosolic acid  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
Cuprizon  (EXP)
curcumin  (EXP)
cyanuric acid  (EXP)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP)
cylindrospermopsin  (ISO)
cypermethrin  (EXP)
D-glucose  (EXP,ISO)
dehydroacetic acid  (EXP)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
Di-n-octyl phthalate  (ISO)
diarsenic trioxide  (ISO)
diazepam  (ISO)
diazinon  (ISO)
diazoxon  (ISO)
dibenziodolium  (ISO)
dicamba  (EXP)
dichlorvos  (ISO)
diclofenac  (EXP,ISO)
diclofop-methyl  (ISO)
dicofol  (ISO)
dicoumarol  (ISO)
dicrotophos  (ISO)
didanosine  (ISO)
diethylstilbestrol  (EXP)
dihydroartemisinin  (ISO)
diisopropyl fluorophosphate  (EXP,ISO)
dimethoate  (ISO)
dimethyl sulfoxide  (EXP,ISO)
dimethylarsinic acid  (ISO)
dioxygen  (EXP,ISO)
diphenylmethane-4,4'-diisocyanate  (EXP,ISO)
disodium selenite  (EXP)
dithionitrobenzoic acid  (ISO)
donepezil hydrochloride  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ecothiopate iodide  (ISO)
efavirenz  (ISO)
elemental selenium  (EXP)
ellagic acid  (ISO)
emtricitabine  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
Erionite  (ISO)
estriol  (ISO)
ethanol  (EXP,ISO)
ethylisopropylamiloride  (ISO)
ethylmercuric chloride  (ISO)
etomidate  (ISO)
fenofibrate  (ISO)
fenoprofen  (ISO)
fenvalerate  (EXP)
ferric ammonium citrate  (ISO)
ferroheme b  (ISO)
ferulic acid  (ISO)
fipronil  (EXP)
flavonoids  (EXP)
flucloxacillin  (ISO)
flurbiprofen  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (EXP)
fructosamine  (ISO)
fructose  (ISO)
furan  (EXP)
furosemide  (ISO)
gallic acid  (EXP)
gamma-tocopherol  (EXP)
genistein  (EXP)
gentamycin  (EXP)
Ginkgoic acid  (EXP)
Ginkgolide A  (ISO)
gliclazide  (EXP,ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glyburide  (ISO)
glycerol  (ISO)
glycidol  (EXP)
glycidyl methacrylate  (ISO)
glycine betaine  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
glycyrrhizinic acid  (ISO)
glyphosate  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
guaiacol  (ISO)
guanidine  (ISO)
gusperimus  (ISO)
halothane  (ISO)
heme b  (ISO)
hemin  (ISO)
heptachlor  (ISO)
hesperetin  (EXP)
hesperidin  (ISO)
Hexachloro-1,3-butadiene  (EXP)
hexadecanoic acid  (ISO)
hexaflumuron  (EXP)
homocysteine  (EXP)
huperzine A  (ISO)
hyaluronic acid  (ISO)
hydralazine  (ISO)
hydrogen chloride  (EXP)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
hydrogencarbonate  (ISO)
hydroquinone  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
hydroxamic acid  (EXP)
hypericin  (ISO)
ibrutinib  (ISO)
ibuprofen  (ISO)
imidacloprid  (EXP)
imipramine  (ISO)
inulin  (ISO)
irbesartan  (ISO)
irinotecan  (ISO)
iron atom  (ISO)
iron trichloride  (EXP)
iron(0)  (ISO)
iron(III) citrate  (ISO)
isocyanuric acid  (EXP)
isoniazide  (ISO)
isotretinoin  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
ketoconazole  (EXP)
ketoprofen  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-cysteine  (ISO)
lamivudine  (ISO)
lead diacetate  (EXP)
lead oxide  (EXP)
lead(0)  (EXP,ISO)
limonene  (EXP)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lithocholic acid  (ISO)
losartan  (ISO)
m-toluic acid  (ISO)
malaoxon  (ISO)
malonaldehyde  (ISO)
mancozeb  (ISO)
maneb  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
mefenamic acid  (ISO)
melamine  (EXP)
melatonin  (EXP)
menadione  (ISO)
menthofuran  (EXP)
meprednisone  (ISO)
mercury atom  (EXP,ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP,ISO)
mesalamine  (EXP)
metformin  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methiocarb  (EXP,ISO)
methotrexate  (EXP,ISO)
methyl beta-cyclodextrin  (EXP)
methylglyoxal  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (EXP)
microcystin RR  (ISO)
microcystin-LR  (EXP,ISO)
mitogen  (EXP)
monocrotaline  (EXP)
montelukast  (EXP)
morphine  (EXP)
Muraglitazar  (ISO)
mycophenolic acid  (ISO)
myricetin  (EXP)
N-acetyl-L-cysteine  (EXP)
N-ethylmaleimide  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naphthalene  (ISO)
naphthalene 1,2-oxide  (ISO)
naproxen  (EXP,ISO)
nefazodone  (ISO)
nelfinavir  (ISO)
nevirapine  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP)
nicorandil  (ISO)
nicotine  (EXP,ISO)
nitrofen  (EXP)
nitrogen dioxide  (ISO)
nitrogen mustard  (ISO)
norelgestromin  (ISO)
o-cresol  (ISO)
O-methyleugenol  (ISO)
o-toluic acid  (ISO)
obeticholic acid  (EXP,ISO)
ochratoxin A  (EXP,ISO)
octadecanoic acid  (ISO)
olanzapine  (ISO)
oleic acid  (ISO)
olmesartan  (ISO)
oltipraz  (EXP)
oridonin  (ISO)
ozone  (EXP,ISO)
p-cresol  (ISO)
p-toluic acid  (ISO)
panaxydol  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
Paraoxon-methyl  (ISO)
paraquat  (EXP)
parathion  (ISO)
parathion-methyl  (ISO)
PD 0325901  (EXP)
pendimethalin  (ISO)
pentanal  (ISO)
peptidoglycan  (ISO)
perfluorobutanesulfonic acid  (EXP,ISO)
perfluorobutyric acid  (EXP,ISO)
perfluorodecanoic acid  (EXP)
perfluorododecanoic acid  (EXP)
perfluorohexanoic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
perindopril  (EXP,ISO)
permethrin  (EXP)
peroxynitrous acid  (ISO)
phenobarbital  (EXP,ISO)
phenol  (ISO)
phenthoate  (ISO)
phenylhydrazine  (EXP)
phlorizin  (ISO)
phorate  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosgene  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
physostigmine  (ISO)
piperine  (EXP)
pirinixic acid  (ISO)
potassium atom  (EXP)
potassium dichromate  (EXP,ISO)
prednisolone  (EXP,ISO)
prednisone  (ISO)
procyanidin B2  (EXP)
profenofos  (ISO)
progesterone  (ISO)
propane-1,2-diol  (ISO)
protein kinase inhibitor  (EXP)
puerarin  (EXP,ISO)
Pyridostigmine bromide  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quinalphos  (EXP)
quinizarin  (ISO)
quinolone  (ISO)
ranitidine  (EXP)
resveratrol  (EXP,ISO)
retinyl acetate  (ISO)
rhodium atom  (ISO)
ritonavir  (ISO)
rivaroxaban  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
salicin  (ISO)
salicyl alcohol  (ISO)
salicylates  (ISO)
salicyluric acid  (ISO)
saquinavir  (ISO)
sarin  (EXP,ISO)
saxitoxin  (ISO)
SB 203580  (ISO)
scoparone  (ISO)
selenium atom  (EXP)
sertraline  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium atom  (EXP)
sodium aurothiosulfate  (ISO)
sodium cholate  (EXP)
sodium cyanide  (ISO)
sodium fluoride  (EXP)
sodium sulfite  (ISO)
sorbinil  (ISO)
stavudine  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
styrene oxide  (ISO)
sulfamethoxazole  (ISO)
sulfisoxazole  (ISO)
sulforaphane  (ISO)
sulindac  (EXP)
Sunset Yellow FCF  (ISO)
superoxide  (ISO)
tacrine  (ISO)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
tartrazine  (ISO)
telmisartan  (ISO)
terephthalic acid  (EXP)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetradecanoic acid  (ISO)
thiabendazole  (EXP)
thiacloprid  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP,ISO)
thiophanate-methyl  (ISO)
thyroxine  (ISO)
titanium dioxide  (ISO)
tolbutamide  (ISO)
tolfenamic acid  (ISO)
tolmetin  (ISO)
Tolmetin glucuronide  (ISO)
toluene  (EXP,ISO)
toluene 2,4-diisocyanate  (ISO)
toluene 2,6-diisocyanate  (ISO)
tolvaptan  (ISO)
tremolite asbestos  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (EXP)
troglitazone  (ISO)
tyloxapol  (ISO)
tyrphostin AG 1478  (ISO)
urea  (ISO)
Ursonic acid  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vanadyl sulfate  (ISO)
vancomycin  (ISO)
venlafaxine hydrochloride  (EXP)
vitamin D  (ISO)
vitamin E  (EXP,ISO)
vorinostat  (ISO)
warfarin  (EXP,ISO)
wogonin  (ISO)
XAV939  (ISO)
zalcitabine  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zileuton  (ISO)
zinc atom  (EXP,ISO)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (ISO)
zinc sulfate  (EXP)
zinc(0)  (EXP,ISO)
ziprasidone  (EXP,ISO)
zoledronic acid  (ISO)
zomepirac  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
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33. Serum albumin level is a significant prognostic factor reflecting disease severity in symptomatic multiple myeloma. Kim JE, etal., Ann Hematol. 2010 Apr;89(4):391-7. doi: 10.1007/s00277-009-0841-4. Epub 2009 Oct 21.
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36. Serum albumin levels in patients with the Zollinger-Ellison syndrome. Lamers CB, etal., Gastroenterology. 1977 Nov;73(5):975-9.
37. Serum albumin and clinical outcome in pediatric cardiac surgery. Leite HP, etal., Nutrition. 2005 May;21(5):553-8.
38. Clinical and pathological investigation of severe COVID-19 patients. Li S, etal., JCI Insight. 2020 May 19. pii: 138070. doi: 10.1172/jci.insight.138070.
39. Preoperative serum albumin level is a prognostic indicator for adenocarcinoma of the gastric cardia. Lien YC, etal., J Gastrointest Surg. 2004 Dec;8(8):1041-8.
40. The amelioration of streptozoticin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription. Liu IM, etal., J Ethnopharmacol. 2009 Apr 24.
41. Albumin levels predict survival in patients with heart failure and preserved ejection fraction. Liu M, etal., Eur J Heart Fail. 2012 Jan;14(1):39-44. doi: 10.1093/eurjhf/hfr154. Epub 2011 Dec 7.
42. Application of albumin prior to delayed thrombolysis reduces brain edema and blood brain barrier permeability in an embolic stroke model. Lu HT, etal., Brain Res. 2012 Feb 15;1438:75-84. doi: 10.1016/j.brainres.2011.12.026. Epub 2011 Dec 20.
43. Polskie Archiwum Medycyny Wewnetrznej Marczewski K, etal., Pol Arch Med Wewn. 1996 Jan;95(1):29-34.
44. Pathophysiology of hypoalbuminemia associated with carcinoid tumor. Mariani G, etal., Cancer. 1976 Aug;38(2):854-60.
45. Protein adducts as biomarkers of exposure to organophosphorus compounds. Marsillach J, etal., Toxicology. 2013 May 10;307:46-54. doi: 10.1016/j.tox.2012.12.007. Epub 2012 Dec 20.
46. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
47. The endothelial nitric oxide synthase gene and risk of diabetic nephropathy and development of cardiovascular disease in type 1 diabetes. Mollsten A, etal., Mol Genet Metab. 2009 May;97(1):80-4. Epub 2009 Feb 3.
48. Factors influencing survival after bypass procedures in patients with advanced pancreatic adenocarcinomas. Muller MW, etal., Am J Surg. 2008 Feb;195(2):221-8.
49. Relationship between serum albumin and parenteral nutrition-associated cholestasis. Nanji AA and Anderson FH, JPEN J Parenter Enteral Nutr. 1984 Jul-Aug;8(4):438-9.
50. Albumin enhances sleep in the young rat. Obal F Jr, etal., Physiol Behav. 1998 Jun 1;64(3):261-6.
51. Gene expression of albumin and liver-specific nuclear transcription factors in liver of protein-deprived rats. Ogawa A, etal., J Nutr. 1997 Jul;127(7):1328-32.
52. Phase II study of second line gemcitabine single chemotherapy for biliary tract cancer patients with 5-fluorouracil refractoriness. Oh SY, etal., Invest New Drugs. 2010 Apr 1.
53. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
54. Assessment of ischaemia-modified albumin level in patients with psoriasis. Ozdemir M, etal., Clin Exp Dermatol. 2012 May 21. doi: 10.1111/j.1365-2230.2012.04384.x.
55. Natural History and Prognostic Factors of Advanced Cholangiocarcinoma without Surgery, Chemotherapy, or Radiotherapy: A Large-Scale Observational Study. Park J, etal., Gut Liver. 2009 Dec;3(4):298-305. Epub 2009 Dec 31.
56. Suckling a protein-restricted rat dam leads to diminished albuminuria in her male offspring in adult life: a longitudinal study. Petry CJ, etal., BMC Nephrol. 2006 Sep 29;7:14.
57. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
58. Upregulation of albumin expression in focal ischemic rat brain. Prajapati KD, etal., Brain Res. 2010 Apr 23;1327:118-24. Epub 2010 Feb 26.
59. Factors associated with increased survival after photodynamic therapy for cholangiocarcinoma. Prasad GA, etal., Clin Gastroenterol Hepatol. 2007 Jun;5(6):743-8.
60. [Relationship between serum albumin level and prognosis in children with sepsis, severe sepsis or septic shock]. Qian SY and Liu J, Zhonghua Er Ke Za Zhi. 2012 Mar;50(3):184-7.
61. Renal protective effect of chronic inhibition of COX-2 with SC-58236 in streptozotocin-diabetic rats. Quilley J, etal., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2316-22. Epub 2011 Mar 25.
62. Catalysis of S-nitrosothiols formation by serum albumin: the mechanism and implication in vascular control. Rafikova O, etal., Proc Natl Acad Sci U S A 2002 Apr 30;99(9):5913-8.
63. Evaluation of nutritional and inflammatory status of advanced colorectal cancer patients and its correlation with survival. Read JA, etal., Nutr Cancer. 2006;55(1):78-85.
64. The albumin receptor effect may be due to a surface-induced conformational change in albumin. Reed RG and Burrington CM, J Biol Chem. 1989 Jun 15;264(17):9867-72.
65. Serum blood urea nitrogen and serum albumin on the first postoperative day predict pancreatic fistula and major complications after pancreaticoduodenectomy. Relles DM, etal., J Gastrointest Surg. 2013 Feb;17(2):326-31. doi: 10.1007/s11605-012-2093-1. Epub 2012 Dec 6.
66. GOA pipeline RGD automated data pipeline
67. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
68. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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70. Nucleotide sequence of cloned rat serum albumin messenger RNA. Sargent TD, etal., Proc Natl Acad Sci U S A 1981 Jan;78(1):243-6.
71. High-resolution analysis of a histone H1 binding site in a rat albumin gene. Sevall JS Biochemistry 1988 Jul 12;27(14):5038-44.
72. Exon skipping during splicing of albumin mRNA precursors in Nagase analbuminemic rats. Shalaby F and Shafritz DA, Proc Natl Acad Sci U S A 1990 Apr;87(7):2652-6.
73. Unique features of non-obstructive emphysema and pure airway obstruction. Sheen S, etal., Int J Tuberc Lung Dis. 2014 Jan;18(1):109-16. doi: 10.5588/ijtld.13.0258.
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75. Albumin endocytosis in endothelial cells induces TGF-beta receptor II signaling. Siddiqui SS, etal., Am J Physiol Lung Cell Mol Physiol. 2004 May;286(5):L1016-26. Epub 2004 Jan 16.
76. The impact of pretransplant hypoalbuminemia on survival in patients with leukemia who underwent allogeneic hematopoietic stem cell transplantation (alloHSCT): a nutritional problem? Sivgin S, etal., Transplant Proc. 2013 Nov;45(9):3371-4. doi: 10.1016/j.transproceed.2013.02.144.
77. Identification of albumin as the plasma carrier for zinc absorption by perfused rat intestine. Smith KT, etal., Biochem J. 1979 Dec 15;184(3):627-33.
78. An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families. Sunthornthepvarakul T, etal., Biochem Biophys Res Commun. 1994 Jul 29;202(2):781-7.
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Additional References at PubMed
PMID:80265   PMID:564345   PMID:893447   PMID:956149   PMID:2437111   PMID:4646766   PMID:6234017   PMID:7798939   PMID:8200992   PMID:8607965   PMID:11197537   PMID:11581259  
PMID:12477932   PMID:12571074   PMID:12970360   PMID:15174051   PMID:15489334   PMID:15576401   PMID:16106354   PMID:16153637   PMID:16169013   PMID:16201370   PMID:16245148   PMID:16283771  
PMID:16289007   PMID:16307046   PMID:16394536   PMID:16405401   PMID:16413734   PMID:16413740   PMID:16413837   PMID:16880525   PMID:17634366   PMID:17879097   PMID:19056867   PMID:19932685  
PMID:19996109   PMID:20452583   PMID:20458337   PMID:21147258   PMID:21276792   PMID:21362503   PMID:21630459   PMID:21805676   PMID:21858039   PMID:22198013   PMID:22516433   PMID:22664934  
PMID:22815976   PMID:23376485   PMID:23533145   PMID:23580065   PMID:25888796   PMID:26025362   PMID:26316108   PMID:26554815   PMID:26806786   PMID:26887834   PMID:28586018   PMID:28805677  
PMID:31691325   PMID:35352799  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
GRCr81417,891,564 - 17,907,043 (-)NCBIGRCr8
mRatBN7.21417,607,397 - 17,622,814 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,607,381 - 17,622,836 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,592,501 - 17,607,638 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,911,425 - 18,926,564 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,610,395 - 17,625,561 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01419,176,275 - 19,191,793 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1419,176,277 - 19,191,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01419,083,045 - 19,098,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41419,126,935 - 19,142,214 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11419,126,964 - 19,142,199 (-)NCBI
Celera1416,973,318 - 16,987,975 (-)NCBICelera
Cytogenetic Map14p22NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38473,404,287 - 73,421,482 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl473,397,114 - 73,421,482 (+)EnsemblGRCh38hg38GRCh38
GRCh37474,270,004 - 74,287,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36474,488,870 - 74,505,996 (+)NCBINCBI36Build 36hg18NCBI36
Build 34474,635,040 - 74,652,167NCBI
Celera471,629,770 - 71,646,928 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef470,081,138 - 70,098,456 (+)NCBIHuRef
CHM1_1474,306,138 - 74,323,296 (+)NCBICHM1_1
T2T-CHM13v2.0476,747,989 - 76,765,185 (+)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39590,608,729 - 90,624,461 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl590,608,756 - 90,624,461 (+)EnsemblGRCm39 Ensembl
GRCm38590,460,870 - 90,476,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,460,897 - 90,476,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37590,889,915 - 90,905,629 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36591,536,101 - 91,551,800 (+)NCBIMGSCv36mm8
Celera588,622,143 - 88,637,838 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.7NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0NW_0049554479,327 - 21,212 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan1-v2356,641,369 - 56,806,795 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1456,829,061 - 56,995,814 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0450,773,244 - 50,790,474 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1456,605,322 - 56,622,418 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl456,605,322 - 56,622,418 (-)Ensemblpanpan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.11362,133,747 - 62,169,349 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1362,053,814 - 62,294,709 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1361,822,278 - 61,838,968 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01362,962,229 - 62,978,876 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1362,962,188 - 62,978,873 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11362,573,750 - 62,590,441 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01362,066,831 - 62,083,527 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01363,202,547 - 63,219,341 (+)NCBIUU_Cfam_GSD_1.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl869,531,487 - 69,721,696 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1869,643,427 - 69,663,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2873,610,472 - 73,630,119 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap8q12NCBI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1721,872,036 - 21,890,095 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl721,876,132 - 21,891,407 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666084909,150 - 931,036 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_00462473534,104,537 - 34,123,624 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473534,105,237 - 34,123,479 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Alb
194 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:17
Count of miRNA genes:16
Interacting mature miRNAs:17
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: