Camk2n1<sup>em1Tja</sup> (calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja) - Rat Genome Database

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Gene: Camk2n1em1Tja (calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja) Rattus norvegicus
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Symbol: Camk2n1em1Tja
Name: calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja
RGD ID: 19259465
Description: This 38-bp deletion mutant allele was generated on an SHR/NCrl background by microinjecting zinc-finger nuclease (ZFN) mRNA (Sigma), targeted to exon 1 of Camk2n1,
INVOLVED IN calcium ion homeostasis; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of systemic arterial blood pressure; ASSOCIATED WITH decreased brown adipose tissue mass; decreased epididymal fat pad weight; decreased heart left ventricle weight
Type: allele  of Camk2n1  
Is Marker For: Strains:   SHR-Camk2n1em1Tja-/-  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Camk2n1 Is a Negative Regulator of Blood Pressure, Left Ventricular Mass, Insulin Sensitivity, and Promotes Adiposity. Alfazema N, etal., Hypertension. 2019 Sep;74(3):687-696. doi: 10.1161/HYPERTENSIONAHA.118.12409. Epub 2019 Jul 22.

Genomics


Related Rat Strains
The following Strains have been annotated to Camk2n1em1Tja


Expression


Sequence

Nucleotide Sequences


Additional Information