Dcxr (dicarbonyl and L-xylulose reductase) - Rat Genome Database

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Gene: Dcxr (dicarbonyl and L-xylulose reductase) Heterocephalus glaber
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Symbol: Dcxr
Name: dicarbonyl and L-xylulose reductase
RGD ID: 18935253
Description: ENCODES a protein that exhibits identical protein binding (ortholog); oxidoreductase activity, acting on CH-OH group of donors (ortholog); oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (ortholog); INVOLVED IN D-glucuronate catabolic process to D-xylulose 5-phosphate (ortholog); NADP metabolic process (ortholog); positive regulation of reactive oxygen species metabolic process (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); obesity (ortholog); pentosuria (ortholog); FOUND IN brush border (ortholog); cytoplasmic microtubule (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: L-xylulose reductase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,865,219 - 10,868,060 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,866,264 - 10,868,064 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dcxr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,865,219 - 10,868,060 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,866,264 - 10,868,064 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DCXR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381782,035,858 - 82,037,697 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1782,035,136 - 82,037,709 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,993,734 - 79,995,573 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,587,046 - 77,588,862 (-)NCBINCBI36Build 36hg18NCBI36
Build 341777,587,045 - 77,588,862NCBI
Celera1776,587,448 - 76,589,264 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,393,877 - 75,395,693 (-)NCBIHuRef
CHM1_11780,079,960 - 80,081,776 (-)NCBICHM1_1
T2T-CHM13v2.01782,903,016 - 82,904,855 (-)NCBIT2T-CHM13v2.0
Dcxr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,615,372 - 120,618,110 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,616,225 - 120,618,107 (-)EnsemblGRCm39 Ensembl
GRCm3811120,724,546 - 120,727,284 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,725,399 - 120,727,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,586,687 - 120,588,595 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,541,491 - 120,543,370 (-)NCBIMGSCv36mm8
Celera11132,460,832 - 132,462,740 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.47NCBI
Dcxr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,504,730 - 106,506,619 (-)NCBIGRCr8
mRatBN7.210106,006,404 - 106,008,293 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx10111,110,399 - 111,112,288 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,573,434 - 110,575,323 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,926,854 - 105,928,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,906,119 - 109,909,696 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,906,815 - 109,909,715 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,499,388 - 109,501,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10104,550,346 - 104,552,236 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
DCXR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,570,108 - 98,572,755 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,470,818 - 103,473,450 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,439,645 - 76,442,282 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11782,145,224 - 82,147,257 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,145,224 - 82,147,257 (-)Ensemblpanpan1.1panPan2
DCXR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19289,864 - 291,518 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9289,889 - 291,480 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha9891,671 - 893,706 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09882,891 - 884,926 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9882,938 - 884,888 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.19908,059 - 910,094 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,034,747 - 1,036,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,113,334 - 1,115,369 (+)NCBIUU_Cfam_GSD_1.0
LOC101967786
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602877,786 - 879,695 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,531,560 - 5,538,105 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,532,264 - 5,534,129 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCXR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12978,139 - 982,259 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112978,131 - 980,042 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DCXR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,923,170 - 73,925,025 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,919,463 - 73,925,277 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,390,184 - 45,392,044 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014225   ⟹   ENSHGLP00000014082
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480110,865,219 - 10,868,060 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014226   ⟹   ENSHGLP00000014083
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480110,866,345 - 10,867,976 (-)Ensembl
RefSeq Acc Id: XM_004861002   ⟹   XP_004861059
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480110,866,264 - 10,868,055 (-)NCBI
RefSeq Acc Id: XM_013078104   ⟹   XP_012933558
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480110,866,264 - 10,868,064 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004861059 (Get FASTA)   NCBI Sequence Viewer  
  XP_012933558 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014082
  ENSHGLP00100024443
GenBank Protein JAO00881 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_012933558   ⟸   XM_013078104
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R4C9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861059   ⟸   XM_004861002
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JBZ7 (UniProtKB/TrEMBL),   G5BJ92 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014082   ⟸   ENSHGLT00000014225
Ensembl Acc Id: ENSHGLP00000014083   ⟸   ENSHGLT00000014226


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010061 Ensembl, ENTREZGENE
  ENSHGLG00100017947 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014225 ENTREZGENE
  ENSHGLT00100024693 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro L-xylulose/Carbonyl_redctase UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
KEGG Report hgl:101724611 UniProtKB/TrEMBL
NCBI Gene Dcxr ENTREZGENE
PANTHER D-ERYTHRULOSE REDUCTASE UniProtKB/TrEMBL
  L-XYLULOSE REDUCTASE UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  adh_short_C2 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0P6JBZ7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R4C9 ENTREZGENE, UniProtKB/TrEMBL
  G5BJ92 ENTREZGENE, UniProtKB/TrEMBL