Cldn1 (claudin 1) - Rat Genome Database

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Gene: Cldn1 (claudin 1) Heterocephalus glaber
Analyze
Symbol: Cldn1
Name: claudin 1
RGD ID: 18933915
Description: ENCODES a protein that exhibits identical protein binding (inferred); structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cellular response to butyrate (ortholog); cellular response to lead ion (ortholog); cellular response to transforming growth factor beta stimulus (ortholog); ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); atopic dermatitis (ortholog); Breast Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); bicellular tight junction (ortholog); cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Claudin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473066,885,319 - 66,903,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473066,885,674 - 66,902,345 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cldn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473066,885,319 - 66,903,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473066,885,674 - 66,902,345 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CLDN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383190,305,707 - 190,322,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3190,305,707 - 190,322,446 (-)EnsemblGRCh38hg38GRCh38
GRCh373190,023,496 - 190,040,235 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363191,506,187 - 191,522,909 (-)NCBINCBI36Build 36hg18NCBI36
Build 343191,506,195 - 191,522,917NCBI
Celera3188,453,968 - 188,470,713 (-)NCBICelera
Cytogenetic Map3q28NCBI
HuRef3187,423,222 - 187,439,968 (-)NCBIHuRef
CHM1_13189,986,455 - 190,003,201 (-)NCBICHM1_1
T2T-CHM13v2.03193,121,997 - 193,138,734 (-)NCBIT2T-CHM13v2.0
Cldn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391626,175,395 - 26,190,589 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1626,175,392 - 26,190,591 (-)EnsemblGRCm39 Ensembl
GRCm381626,356,645 - 26,371,839 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1626,356,642 - 26,371,841 (-)EnsemblGRCm38mm10GRCm38
MGSCv371626,356,737 - 26,371,925 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361626,272,000 - 26,287,188 (-)NCBIMGSCv36mm8
Celera1626,899,939 - 26,915,115 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1618.0NCBI
Cldn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81187,926,376 - 87,941,533 (+)NCBIGRCr8
mRatBN7.21174,421,569 - 74,436,728 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,421,569 - 74,436,724 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1183,230,293 - 83,245,398 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01175,865,333 - 75,880,440 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01174,926,942 - 74,942,078 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01177,815,216 - 77,830,373 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1177,815,181 - 77,830,416 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,888,890 - 82,904,926 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,473,654 - 76,488,809 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,531,242 - 76,546,394 (+)NCBI
Celera1173,332,294 - 73,347,451 (+)NCBICelera
Cytogenetic Map11q22NCBI
Cldn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542017,798,974 - 17,815,205 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542017,798,974 - 17,815,049 (+)NCBIChiLan1.0ChiLan1.0
CLDN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22188,174,529 - 188,191,447 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13188,179,246 - 188,196,102 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03187,328,629 - 187,345,360 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13195,882,239 - 195,898,990 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3195,882,239 - 195,899,248 (-)Ensemblpanpan1.1panPan2
CLDN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13422,303,058 - 22,319,101 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3422,303,850 - 22,319,033 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3426,396,629 - 26,412,654 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03422,237,734 - 22,253,834 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3422,238,526 - 22,254,024 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13422,258,709 - 22,274,790 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03422,245,945 - 22,262,037 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03422,487,908 - 22,503,999 (-)NCBIUU_Cfam_GSD_1.0
Cldn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602114,006,644 - 114,021,281 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493657898,273 - 113,153 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493657898,489 - 113,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLDN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13127,712,777 - 127,730,657 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113127,714,857 - 127,730,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213136,971,674 - 136,987,446 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CLDN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11584,518,464 - 84,533,587 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1584,516,478 - 84,532,969 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604158,103,316 - 58,119,871 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025715   ⟹   ENSHGLP00000025489
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473066,885,319 - 66,903,079 (+)Ensembl
RefSeq Acc Id: XM_004834786   ⟹   XP_004834843
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473066,885,674 - 66,902,345 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834843 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08519 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025489
GenBank Protein JAO01420 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004834843   ⟸   XM_004834786
- UniProtKB: G5BGV8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025489   ⟸   ENSHGLT00000025715


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018158 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025715 ENTREZGENE
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro Claudin UniProtKB/TrEMBL
  Claudin1 UniProtKB/TrEMBL
  Claudin_CS UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
KEGG Report hgl:101709404 UniProtKB/TrEMBL
NCBI Gene Cldn1 ENTREZGENE
PANTHER PTHR12002 UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
PRINTS CLAUDIN UniProtKB/TrEMBL
  CLAUDIN1 UniProtKB/TrEMBL
PROSITE CLAUDIN UniProtKB/TrEMBL
UniProt G5BGV8 ENTREZGENE, UniProtKB/TrEMBL